Crosstalk between Gαi- and Gαq-coupled receptors is mediated by Gβγ exchange

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 19, 1999, Pages 10626-10631

  Quitterer, Ursula ^a   Lohse, Martin J ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BRADYKININ B2 RECEPTOR; BRADYKININ RECEPTOR; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; INOSITOL PHOSPHATE; PHOSPHOLIPASE C; URIDINE TRIPHOSPHATE; ADENOSINE A1 RECEPTOR; ALPHA 2C ADRENERGIC RECEPTOR; BRADYKININ; PURINE P2Y RECEPTOR;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL STRAIN COS1; DOSE RESPONSE; GENETIC TRANSFECTION; IMMUNOBLOTTING; METABOLISM; MUTAGENESIS; PHYSIOLOGY; SIGNAL TRANSDUCTION; TIME; ANIMAL CELL; BINDING AFFINITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RECEPTOR BINDING; RECEPTOR UPREGULATION;

ANIMALS; CALCIUM; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEINS; IMMUNOBLOTTING; INOSITOL PHOSPHATES; MODELS, BIOLOGICAL; MUTAGENESIS; PHOSPHOLIPASE C; RECEPTOR CROSS-TALK; RECEPTOR, BRADYKININ B2; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, BRADYKININ; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; URIDINE TRIPHOSPHATE;

EID: 0032588307     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.19.10626     Document Type: Article

References (34)

1. Kleuss, C., Scherübl, H., Hescheler, J., Schultz, G. & Wittig, B. (1993) Science 259, 832-834.
2. Kalkbrenner, F., Degtiar, V. E., Schenker, M., Brendel, S., Zobel, A., Hescheler, J., Wittig, B. & Schultz, G. (1995) EMBO J. 14, 4728-4737.
3. Macrez-Leprêtre, N., Kalkbrenner, F., Morel, J.-L., Schultz, G. & Mironneau, J. (1997) J. Biol. Chem. 272, 10095-10102.
4. Dippel, E., Kalkbrenner, F., Wittig, B. & Schultz, G. (1996) Proc. Natl. Acad. Sci. USA 93, 1391-1396.
5. Wang, Q., Mullah, B., Hansen, C., Asundi, J. & Robishaw, J. D. (1997) J. Biol. Chem. 272, 26040-26048.
6. Zhu, X. & Birnbaumer, L. (1996) Proc. Natl. Acad. Sci. USA 93, 2827-2831.
7. Iñiguez-Lluhi, J. A., Simon, M. I., Robishaw, J. D. & Gilman, A. G. (1992) J. Biol. Chem. 267, 23409-23417.
8. Müller, S., Hekman, M. & Lohse, M. J. (1993) Proc. Natl. Acad. Sci. USA 90, 10439-10443.
9. Ueda, N., Iñiguez-Lluhi, J. A., Lee, E., Smrcka, A. V., Robishaw, J. D. & Gilman, A. G. (1994) J. Biol. Chem. 269, 4388-4395.
10. Müller, S., Straub, A., Schröder, S., Bauer, P. & Lohse, M. J. (1996) J. Biol. Chem. 271, 11781-11786.
11. Hollingsworth, E. B., de la Cruz, R. A. & Daly, J. W. (1986) Eur. J. Pharmacol. 122, 45-50.
12. Neer, E. J. (1995) Cell 80, 249-257.
13. Müller, S. & Lohse, M. J. (1995) Biochem. Soc. Trans. 23, 141-148.
14. Freund, S., Ungerer, M. & Lohse, M. J. (1994) Naunyn-Schmiedeberg's Arch. Pharmacol. 350, 49-56.
15. Gerwins, P. & Fredholm, B. B. (1992) Proc. Natl. Acad. Sci. USA 89, 7330-7334.
16. Tomura, H., Itoh, H., Sho, K., Sato, K., Nagao, M., Ui, M., Kondo, Y. & Okajima, F. (1997) J. Biol. Chem. 272, 23130-23137.
17. Camps, M., Carozzi, A., Schnabel, P., Scheer, A., Parker, P. J. & Gierschik, P. (1992) Nature (London) 360, 684-686.
18. Smrcka, A. V. & Sternweis. P. C. (1993) J. Biol. Chem. 268, 9667-9674.
19. Hepler, K. R., Kozasa, T., Smrcka, A. V., Simon, M. I., Ree, S. G., Sternweis, P. C. & Gilman, A. G. (1993) J. Biol. Chem. 268, 14367-14375.
20. McEachern, A. E., Shelton, E. R., Bhakta, S., Obernolte, R., Bach, C., Zuppan, P., Fujisaki, J., Aldrich, R. W. & Jarnagin, K. (1991) Proc. Natl. Acad. Sci. USA 88, 7724-7728.
21. Fredholm, B. B., Abracchio, M. P., Burnstock, G., Dubyak, G. R., Harden, T. K., Jacobson, K. A., Schwabe, U. & Williams M. (1997) Trends Pharmacol. Sci. 18, 79-82.
22. Seyedi, N., Win, T., Lander, H. M. & Levi, R. (1997) Circ. Res. 81, 774-784.
23. Zhang, S., Coso, O. A., Collins, R., Gutkind, J. S. & Simonds, W. F. (1996) J. Biol. Chem. 271, 20208-20212.
24. AbdAlla, S., Quitterer, U., Grigoriev, S., Maidhof, A., Haasemann, M., Jarnagin, K. & Müller-Esterl, W. (1996) J. Biol. Chem. 271, 1748-1755.
25. Quitterer, U., Zaki, E. & AbdAlla, S. (1999) J. Biol. Chem. 274, 14773-14778.
26. Kisselev, O. G., Ermolaeva, M. V. & Gautam, N. (1994) J. Biol. Chem. 269, 21399-21402.
27. Pronin, A. N. & Gautam, N. (1992) Proc. Natl. Acad. Sci. USA 89, 6220-6224.
28. Schmidt, C. J., Thomas, T. C., Levine, M. A. & Neer, E. J. (1992) J. Biol. Chem. 267, 13807-13810.
29. Phillips, W. J., Wong, S. C. & Cerione, R. A. (1992) J. Biol. Chem. 267, 17040-17046.
30. Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649.
31. Biden, T. J. & Browne C. L. (1993) Biochem. J. 293, 721-728.
32. Jiang, H., Kuang, Y., Wu, Y., Smrcka, A., Simon, M. I. & Wu, D. (1996) J. Biol. Chem. 271, 13430-13434.
33. Cheng, D. Y., DeWitt, B. J., Suzuki, F., Neely, C. F. & Kadowitz, P. J. (1996) Am. J. Physiol. 270, H200-H297.
34. Boehm, S. & Huck, S. (1997) Br. J. Pharmacol. 122, 455-462.