-
1
-
-
70349957947
-
Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans
-
Artal-Sanz M, Tavernarakis N (2009) Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans. Nature 461:793-797
-
(2009)
Nature
, vol.461
, pp. 793-797
-
-
Artal-Sanz, M.1
Tavernarakis, N.2
-
2
-
-
0033972463
-
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
-
Barja G, Herrero A (2000) Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J 14:312-318 (Pubitemid 30086068)
-
(2000)
FASEB Journal
, vol.14
, Issue.2
, pp. 312-318
-
-
Barja, G.1
Herrero, A.2
-
3
-
-
0031574362
-
Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging
-
DOI 10.1016/S0169-328X(97)00278-7, PII S0169328X97002787
-
Barrientos A, Casademont J, Cardellach F et al (1997) Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging. Brain Res Mol Brain Res 52:284-289 (Pubitemid 28043472)
-
(1997)
Molecular Brain Research
, vol.52
, Issue.2
, pp. 284-289
-
-
Barrientos, A.1
Casademont, J.2
Cardellach, F.3
Estivill, X.4
Urbano-Marquez, A.5
Nunes, V.6
-
4
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB, Ames BN (1998) The free radical theory of aging matures. Physiol Rev 78:547-581 (Pubitemid 28182903)
-
(1998)
Physiological Reviews
, vol.78
, Issue.2
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
5
-
-
33846002728
-
+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth
-
DOI 10.1016/j.ccr.2006.10.020, PII S1535610806003722
-
Bonnet S, Archer SL, Allalunis-Turner J et al (2007) A mitochondria- K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 11:37-51 (Pubitemid 46054520)
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
Haromy, A.4
Beaulieu, C.5
Thompson, R.6
Lee, C.T.7
Lopaschuk, G.D.8
Puttagunta, L.9
Bonnet, S.10
Harry, G.11
Hashimoto, K.12
Porter, C.J.13
Andrade, M.A.14
Thebaud, B.15
Michelakis, E.D.16
-
6
-
-
79958128149
-
Studies of the common aerobic spore-forming bacilli: I. Staining for fat with Sudan black B-safranin
-
Burdon KL, Stokes JC, Kimbrough CE (1942) Studies of the common aerobic spore-forming bacilli: I. Staining for fat with Sudan black B-safranin. J Bacteriol 43:717-724
-
(1942)
J Bacteriol
, vol.43
, pp. 717-724
-
-
Burdon, K.L.1
Stokes, J.C.2
Kimbrough, C.E.3
-
7
-
-
62149086299
-
Number matters: Control of mammalian mitochondrial DNA copy number
-
Clay Montier LL, Deng JJ, Bai Y (2009) Number matters: control of mammalian mitochondrial DNA copy number. J Genet Genomics 36:125-131
-
(2009)
J Genet Genomics
, vol.36
, pp. 125-131
-
-
Clay Montier, L.L.1
Deng, J.J.2
Bai, Y.3
-
8
-
-
0007148187
-
Psychology of the scientist: X. Observer bias in classical conditioning of the planaria
-
Cordaro L, Ison JR (1963) Psychology of the scientist: X. Observer bias in classical conditioning of the planaria. Psychol Rep 13:787-789
-
(1963)
Psychol Rep
, vol.13
, pp. 787-789
-
-
Cordaro, L.1
Ison, J.R.2
-
10
-
-
34648813720
-
ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
-
DOI 10.1038/nrm2256, PII NRM2256
-
D'Autreaux B, Toledano MB (2007) ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 8:813-824 (Pubitemid 47462134)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.10
, pp. 813-824
-
-
D'Autreaux, B.1
Toledano, M.B.2
-
11
-
-
0030463813
-
Effect of colour of drugs: Systematic review of perceived effect of drugs and of their effectiveness
-
de Craen AJ, Roos PJ, Leonard dV et al (1996) Effect of colour of drugs: systematic review of perceived effect of drugs and of their effectiveness. BMJ 313:1624-1626
-
(1996)
BMJ
, vol.313
, pp. 1624-1626
-
-
De Craen, A.J.1
Roos, P.J.2
DV, L.3
-
12
-
-
29744435923
-
Cells discover fire: Employing reactive oxygen species in development and consequences for aging
-
de Magalhaes JP, Church GM (2006) Cells discover fire: employing reactive oxygen species in development and consequences for aging. Exp Gerontol 41:1-10
-
(2006)
Exp Gerontol
, vol.41
, pp. 1-10
-
-
De Magalhaes, J.P.1
Church, G.M.2
-
14
-
-
13744258936
-
The influence of genes on the aging process of mice: A statistical assessment of the genetics of aging
-
DOI 10.1534/genetics.104.032292
-
de Magalhaes JP, Cabral JA, Magalhaes D (2005) The influence of genes on the aging process of mice: a statistical assessment of the genetics of aging. Genetics 169: 265-274 (Pubitemid 40239169)
-
(2005)
Genetics
, vol.169
, Issue.1
, pp. 265-274
-
-
De Magalhaes, J.P.1
Cabral, J.A.S.2
Magalhaes, D.3
-
15
-
-
0029065413
-
The effects of dichloroacetate on lactate accumulation and endurance in an exercising rat model
-
Durkot MJ, De Garavilla L, Caretti D et al (1995) The effects of dichloroacetate on lactate accumulation and endurance in an exercising rat model. Int J Sports Med 16:167-171
-
(1995)
Int J Sports Med
, vol.16
, pp. 167-171
-
-
Durkot, M.J.1
De Garavilla, L.2
Caretti, D.3
-
18
-
-
0025196557
-
Slow mortality rate accelerations during aging in some animals approximate that of humans
-
Finch CE, Pike MC, Witten M (1990) Slow mortality rate accelerations during aging in some animals approximate that of humans. Science 249:902-905
-
(1990)
Science
, vol.249
, pp. 902-905
-
-
Finch, C.E.1
Pike, M.C.2
Witten, M.3
-
19
-
-
79958081236
-
Measuring reactive oxygen species in C. elegans using DCFDA - A word of caution
-
Fong S, Gruber J, Halliwell B (2010) Measuring reactive oxygen species in C. elegans using DCFDA - a word of caution. Worm Breeder's Gaz 18:11
-
(2010)
Worm Breeder's Gaz
, vol.18
, pp. 11
-
-
Fong, S.1
Gruber, J.2
Halliwell, B.3
-
20
-
-
65749097288
-
Changing course in ageing research: The healthy ageing phenotype
-
Franco OH, Karnik K, Osborne G et al (2009) Changing course in ageing research: the healthy ageing phenotype. Maturitas 63:13-19
-
(2009)
Maturitas
, vol.63
, pp. 13-19
-
-
Franco, O.H.1
Karnik, K.2
Osborne, G.3
-
21
-
-
0026712284
-
Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats
-
Gadaleta MN, Rainaldi G, Lezza AM et al (1992) Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats. Mutat Res 275:181-193
-
(1992)
Mutat Res
, vol.275
, pp. 181-193
-
-
Gadaleta, M.N.1
Rainaldi, G.2
Lezza, A.M.3
-
22
-
-
0018894725
-
A simple method for maintaining large, aging populations of Caenorhabditis elegans
-
DOI 10.1016/0047-6374(80)90090-1
-
Gandhi S, Santelli J, Mitchell DH et al (1980) A simple method for maintaining large, aging populations of Caenorhabditis elegans. Mech Ageing Dev 12:137-150 (Pubitemid 10113067)
-
(1980)
Mechanisms of Ageing and Development
, vol.12
, Issue.2
, pp. 137-150
-
-
Gandhi, S.1
Santelli, J.2
Mitchell, D.H.3
-
23
-
-
5444244873
-
Aging in a very short-lived nematode
-
DOI 10.1016/j.exger.2004.06.011, PII S0531556504002128
-
Gardner MP, Gems D, Viney ME (2004) Aging in a very short-lived nematode. Exp Gerontol 39:1267-1276 (Pubitemid 39360367)
-
(2004)
Experimental Gerontology
, vol.39
, Issue.9
, pp. 1267-1276
-
-
Gardner, M.P.1
Gems, D.2
Viney, M.E.3
-
24
-
-
70350660932
-
Ageing and oxidants in the nematode Caenorhabditis elegans
-
Gems D (2009) Ageing and oxidants in the nematode Caenorhabditis elegans. SEB Exp Biol Ser 62:31-56
-
(2009)
SEB Exp Biol Ser
, vol.62
, pp. 31-56
-
-
Gems, D.1
-
25
-
-
0035370372
-
Insulin/IGF signalling and ageing: Seeing the bigger picture
-
DOI 10.1016/S0959-437X(00)00192-1
-
Gems D, Partridge L (2001) Insulin/IGF signalling and ageing: seeing the bigger picture. Curr Opin Genet Dev 11: 287-292 (Pubitemid 32480295)
-
(2001)
Current Opinion in Genetics and Development
, vol.11
, Issue.3
, pp. 287-292
-
-
Gems, D.1
Partridge, L.2
-
26
-
-
71849114694
-
Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers
-
Giustarini D, Dalle-Donne I, Tsikas D et al (2009) Oxidative stress and human diseases: origin, link, measurement, mechanisms, and biomarkers. Crit Rev Clin Lab Sci 46:241-281
-
(2009)
Crit Rev Clin Lab Sci
, vol.46
, pp. 241-281
-
-
Giustarini, D.1
Dalle-Donne, I.2
Tsikas, D.3
-
27
-
-
70350149982
-
A novel function of lipid droplets in regulating longevity
-
Goldberg AA, Bourque SD, Kyryakov P et al (2009) A novel function of lipid droplets in regulating longevity. Biochem Soc Trans 37:1050-1055
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 1050-1055
-
-
Goldberg, A.A.1
Bourque, S.D.2
Kyryakov, P.3
-
28
-
-
1042268861
-
Mitochondrial complex I mutations in Caenorhabditis elegans produce cytochrome c oxidase deficiency, oxidative stress and vitamin-responsive lactic acidosis
-
DOI 10.1093/hmg/ddh027
-
Grad LI, Lemire BD (2004) Mitochondrial complex I mutations in Caenorhabditis elegans produce cytochrome c oxidase deficiency, oxidative stress and vitaminresponsive lactic acidosis. Hum Mol Genet 13:303-314 (Pubitemid 38196170)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.3
, pp. 303-314
-
-
Grad, L.I.1
Lemire, B.D.2
-
29
-
-
50249094970
-
The mitochondrial free radical theory of ageing - Where do we stand?
-
Gruber J, Schaffer S, Halliwell B (2008) The mitochondrial free radical theory of ageing - where do we stand? Front Biosci 13:6554-6579
-
(2008)
Front Biosci
, vol.13
, pp. 6554-6579
-
-
Gruber, J.1
Schaffer, S.2
Halliwell, B.3
-
30
-
-
70350676299
-
Deceptively simple but simply deceptive - Caenorhabditis elegans lifespan studies: Considerations for aging and antioxidant effects
-
Gruber J, Ng LF, Poovathingal SK et al (2009) Deceptively simple but simply deceptive - Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects. FEBS Lett 583:3377-3387
-
(2009)
FEBS Lett
, vol.583
, pp. 3377-3387
-
-
Gruber, J.1
Ng, L.F.2
Poovathingal, S.K.3
-
31
-
-
77952369216
-
Caenorhabditis elegans life span studies: The challenge of maintaining synchronous cohorts
-
Gruber J, Poovathingal SK, Schaffer S et al (2010) Caenorhabditis elegans life span studies: the challenge of maintaining synchronous cohorts. Rejuvenation Res 13: 347-349
-
(2010)
Rejuvenation Res
, vol.13
, pp. 347-349
-
-
Gruber, J.1
Poovathingal, S.K.2
Schaffer, S.3
-
32
-
-
0033042955
-
Establishing the significance and optimal intake of dietary antioxidants: The biomarker concept
-
Halliwell B (1999) Establishing the significance and optimal intake of dietary antioxidants: the biomarker concept. Nutr Rev 57:104-113
-
(1999)
Nutr Rev
, vol.57
, pp. 104-113
-
-
Halliwell, B.1
-
34
-
-
2942572700
-
Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean?
-
Halliwell B, Whiteman M (2004) Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br J Pharmacol 142:231-255
-
(2004)
Br J Pharmacol
, vol.142
, pp. 231-255
-
-
Halliwell, B.1
Whiteman, M.2
-
35
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11:298-300
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
36
-
-
0038160752
-
The induction of oxidative stress and cellular death by the drinking water disinfection by-products, dichloroacetate and trichloroacetate in J774.A1 cells
-
DOI 10.1016/S1532-0456(03)00082-6
-
Hassoun EA, Ray S (2003) The induction of oxidative stress and cellular death by the drinking water disinfection by-products, dichloroacetate and trichloroacetate in J774.A1 cells. Comp Biochem Physiol C 135:119-128 (Pubitemid 36835923)
-
(2003)
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology
, vol.135
, Issue.2
, pp. 119-128
-
-
Hassoun, E.A.1
Ray, S.2
-
37
-
-
0034626766
-
The future of ageing
-
Hayflick L (2000) The future of ageing. Nature 408:267-269
-
(2000)
Nature
, vol.408
, pp. 267-269
-
-
Hayflick, L.1
-
38
-
-
1842685103
-
Markers of protein oxidation: Different oxidants give rise to variable yields of bound and released carbonyl products
-
DOI 10.1016/j.freeradbiomed.2004.02.017, PII S0891584904001352
-
Headlam HA, Davies MJ (2004) Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products. Free Radic Biol Med 36: 1175-1184 (Pubitemid 38479871)
-
(2004)
Free Radical Biology and Medicine
, vol.36
, Issue.9
, pp. 1175-1184
-
-
Headlam, H.A.1
Davies, M.J.2
-
39
-
-
0037167855
-
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
-
DOI 10.1038/nature01135
-
Herndon LA, Schmeissner PJ, Dudaronek JM et al (2002) Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419:808-814 (Pubitemid 35238561)
-
(2002)
Nature
, vol.419
, Issue.6909
, pp. 808-814
-
-
Herndon, L.A.1
Schmeissner, P.J.2
Dudaronek, J.M.3
Brown, P.A.4
Listner, K.M.5
Sakano, Y.6
Paupard, M.C.7
Hall, D.H.8
Driscoll, M.9
-
40
-
-
65349121253
-
Quantitative lipid analysis and life span of the fat-3 mutant of Caenorhabditis elegans
-
Hillyard SL, German JB (2009) Quantitative lipid analysis and life span of the fat-3 mutant of Caenorhabditis elegans. J Agric Food Chem 57:3389-3396
-
(2009)
J Agric Food Chem
, vol.57
, pp. 3389-3396
-
-
Hillyard, S.L.1
German, J.B.2
-
41
-
-
22144488142
-
Metabolism, physiology and stress defense in three aging Ins/IGF-1 mutants of the nematode Caenorhabditis elegans
-
DOI 10.1111/j.1474-9726.2005.00150.x
-
Houthoofd K, Fidalgo MA, Hoogewijs D et al (2005) Metabolism, physiology and stress defense in three aging Ins/ IGF-1 mutants of the nematode Caenorhabditis elegans. Aging Cell 4:87-95 (Pubitemid 41632907)
-
(2005)
Aging Cell
, vol.4
, Issue.2
, pp. 87-95
-
-
Houthoofd, K.1
Fidalgo, M.A.2
Hoogewijs, D.3
Braeckman, B.P.4
Lenaerts, I.5
Brys, K.6
Matthijssens, F.7
De Vreese, A.8
Van Eygen, S.9
Munoz, M.J.10
Vanfleteren, J.R.11
-
43
-
-
14744296990
-
On the importance of fatty acid composition of membranes for aging
-
Hulbert AJ (2005) On the importance of fatty acid composition of membranes for aging. J Theor Biol 234:277-288
-
(2005)
J Theor Biol
, vol.234
, pp. 277-288
-
-
Hulbert, A.J.1
-
44
-
-
2942674875
-
Ill or just old? Towards a conceptual framework of the relation between ageing and disease
-
Izaks GJ, Westendorp RG (2003) Ill or just old? Towards a conceptual framework of the relation between ageing and disease. BMC Geriatr 3:7
-
(2003)
BMC Geriatr
, vol.3
, pp. 7
-
-
Izaks, G.J.1
Westendorp, R.G.2
-
45
-
-
0014869029
-
Development of fluorescence between o-phthaldialdehyde and thiols
-
Jocelyn PC, Kamminga A (1970) Development of fluorescence between o-phthaldialdehyde and thiols. Anal Biochem 37:417-421
-
(1970)
Anal Biochem
, vol.37
, pp. 417-421
-
-
Jocelyn, P.C.1
Kamminga, A.2
-
46
-
-
0024314677
-
Effect of dichloroacetate on regional energy metabolites and pyruvate dehydrogenase activity during ischemia and reperfusion in gerbil brain
-
DOI 10.1111/j.1471-4159.1989.tb07262.x
-
Katayama Y, Welsh FA (1989) Effect of dichloroacetate on regional energy metabolites and pyruvate dehydrogenase activity during ischemia and reperfusion in gerbil brain. J Neurochem 52:1817-1822 (Pubitemid 19140768)
-
(1989)
Journal of Neurochemistry
, vol.52
, Issue.6
, pp. 1817-1822
-
-
Katayama, Y.1
Welsh, F.A.2
-
47
-
-
77950200010
-
The genetics of ageing
-
Kenyon CJ (2010) The genetics of ageing. Nature 464:504-512
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
48
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
DOI 10.1126/science.277.5328.942
-
Kimura KD, Tissenbaum HA, Liu Y et al (1997) Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277:942-946 (Pubitemid 27366677)
-
(1997)
Science
, vol.277
, Issue.5328
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
49
-
-
0031239286
-
Activation of pyruvate dehydrogenase improves heart function and metabolism after hemorrhagic shock
-
DOI 10.1006/jmcc.1997.0483
-
Kline JA, Maiorano PC, Schroeder JD et al (1997) Activation of pyruvate dehydrogenase improves heart function and metabolism after hemorrhagic shock. J Mol Cell Cardiol 29:2465-2474 (Pubitemid 27404438)
-
(1997)
Journal of Molecular and Cellular Cardiology
, vol.29
, Issue.9
, pp. 2465-2474
-
-
Kline, J.A.1
Maiorano, P.C.2
Schroeder, J.D.3
Grattan, R.M.4
Vary, T.C.5
Watts, J.A.6
-
50
-
-
0027365312
-
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
-
DOI 10.1016/0891-5849(93)90165-Q
-
Ku HH, Brunk UT, Sohal RS (1993) Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Radic Biol Med 15:621-627 (Pubitemid 23353411)
-
(1993)
Free Radical Biology and Medicine
, vol.15
, Issue.6
, pp. 621-627
-
-
Ku, H.-H.1
Brunk, U.T.2
Sohal, R.S.3
-
51
-
-
73749087580
-
Mitochondrial function as a determinant of life span
-
Lanza IR, Nair KS (2010) Mitochondrial function as a determinant of life span. Pflug Arch 459:277-289
-
(2010)
Pflug Arch
, vol.459
, pp. 277-289
-
-
Lanza, I.R.1
Nair, K.S.2
-
54
-
-
34247623639
-
Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging
-
Lee HC, Wei YH (2007) Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging. Exp Biol Med 232: 592-606
-
(2007)
Exp Biol Med
, vol.232
, pp. 592-606
-
-
Lee, H.C.1
Wei, Y.H.2
-
55
-
-
0027263281
-
Effects of dichloroacetate on exercise performance in healthy volunteers
-
Ludvik B, Mayer G, Stifter S et al (1993) Effects of dichloroacetate on exercise performance in healthy volunteers. Pflug Arch 423:251-254 (Pubitemid 23137301)
-
(1993)
Pflugers Archiv European Journal of Physiology
, vol.423
, Issue.3-4
, pp. 251-254
-
-
Ludvik, B.1
Mayer, G.2
Stifter, S.3
Putz, D.4
Barnas, U.5
Graf, H.6
-
56
-
-
77749304032
-
Signaling by ROS drives inflammasome activation
-
Martinon F (2010) Signaling by ROS drives inflammasome activation. Eur J Immunol 40:616-619
-
(2010)
Eur J Immunol
, vol.40
, pp. 616-619
-
-
Martinon, F.1
-
57
-
-
11144264697
-
Alpha MUPA mice: A transgenic model for longevity induced by caloric restriction
-
DOI 10.1016/j.mad.2004.08.018, PII S0047637404001988, The Voyage to Old Age: Searching for Human Longevity Genes
-
Miskin R, Tirosh O, Pardo M et al (2005) Alpha MUPA mice: a transgenic model for longevity induced by caloric restriction. Mech Ageing Dev 126:255-261 (Pubitemid 40038346)
-
(2005)
Mechanisms of Ageing and Development
, vol.126
, Issue.2
, pp. 255-261
-
-
Miskin, R.1
Tirosh, O.2
Pardo, M.3
Zusman, I.4
Schwartz, B.5
Yahav, S.6
Dubnov, G.7
Kohen, R.8
-
58
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy MP (2009) How mitochondria produce reactive oxygen species. Biochem J 417:1-13
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
59
-
-
46049096732
-
A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted
-
Nagendran J, Gurtu V, Fu DZ et al (2008) A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted. J Thorac Cardiovasc Surg 136:168-178
-
(2008)
J Thorac Cardiovasc Surg
, vol.136
, pp. 168-178
-
-
Nagendran, J.1
Gurtu, V.2
Fu, D.Z.3
-
60
-
-
29544436107
-
Platelet mitochondrial evaluation during cytochrome c and dichloroacetate treatments of MELAS
-
DOI 10.1016/j.mito.2005.10.002, PII S1567724905001169
-
Nakano K, Tarashima M, Tachikawa E et al (2005) Platelet mitochondrial evaluation during cytochrome c and dichloroacetate treatments of MELAS. Mitochondrion 5:426-433 (Pubitemid 43013024)
-
(2005)
Mitochondrion
, vol.5
, Issue.6
, pp. 426-433
-
-
Nakano, K.1
Tarashima, M.2
Tachikawa, E.3
Noda, N.4
Nakayama, T.5
Sasaki, K.6
Mizoguchi, E.7
Matsuzaki, M.8
Osawa, M.9
-
62
-
-
36048939348
-
Benchmarks for ageing studies
-
DOI 10.1038/450165a, PII 450165A
-
Partridge L, Gems D (2007) Benchmarks for ageing studies. Nature 450:165-167 (Pubitemid 350100518)
-
(2007)
Nature
, vol.450
, Issue.7167
, pp. 165-167
-
-
Partridge, L.1
Gems, D.2
-
63
-
-
34548790754
-
Mitochondria and ageing: Winning and losing in the numbers game
-
DOI 10.1002/bies.20634
-
Passos JF, von Zglinicki T, Kirkwood TB (2007) Mitochondria and ageing: winning and losing in the numbers game. Bioessays 29:908-917 (Pubitemid 47424900)
-
(2007)
BioEssays
, vol.29
, Issue.9
, pp. 908-917
-
-
Passos, J.F.1
Von Zglinicki, T.2
Kirkwood, T.B.L.3
-
65
-
-
73449083412
-
Stochastic drift in mitochondrial DNA point mutations: A novel perspective ex silico
-
Poovathingal SK, Gruber J, Halliwell B et al (2009) Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico. PLoS Comput Biol 5:e1000572
-
(2009)
PLoS Comput Biol
, vol.5
-
-
Poovathingal, S.K.1
Gruber, J.2
Halliwell, B.3
-
66
-
-
0019472444
-
Dichloroacetate: Effects on exercise endurance in untrained rats
-
Schneider SH, Komanicky PM, Goodman MN et al (1981) Dichloroacetate: effects on exercise endurance in untrained rats. Metabolism 30:590-595
-
(1981)
Metabolism
, vol.30
, pp. 590-595
-
-
Schneider, S.H.1
Komanicky, P.M.2
Goodman, M.N.3
-
67
-
-
0029652606
-
The methodologic quality of randomization as assessed from reports of trials in specialist and general medical journals
-
Schulz KF, Chalmers I, Altman DG et al (1995) The methodologic quality of randomization as assessed from reports of trials in specialist and general medical journals. Online J Curr Clin Trials Doc No 197:81
-
(1995)
Online J Curr Clin Trials Doc No
, vol.197
, pp. 81
-
-
Schulz, K.F.1
Chalmers, I.2
Altman, D.G.3
-
68
-
-
40849111674
-
Age-dependent kinetics and metabolism of dichloroacetate: Possible relevance to toxicity
-
DOI 10.1124/jpet.107.134593
-
Shroads AL, Guo X, Dixit V et al (2008) Age-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity. J Pharmacol Exp Ther 324:1163-1171 (Pubitemid 351397850)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.324
, Issue.3
, pp. 1163-1171
-
-
Shroads, A.L.1
Guo, X.2
Dixit, V.3
Liu, H.-P.4
James, M.O.5
Stacpoole, P.W.6
-
69
-
-
66049160126
-
The ageing epigenome: Damaged beyond repair?
-
Sinclair DA, Oberdoerffer P (2009) The ageing epigenome: damaged beyond repair? Ageing Res Rev 8:189-198
-
(2009)
Ageing Res Rev
, vol.8
, pp. 189-198
-
-
Sinclair, D.A.1
Oberdoerffer, P.2
-
70
-
-
0036710886
-
Mechanisms of aging: An appraisal of the oxidative stress hypothesis
-
DOI 10.1016/S0891-5849(02)00886-9, PII S0891584902008869
-
Sohal RS, Mockett RJ, Orr WC (2002) Mechanisms of aging: an appraisal of the oxidative stress hypothesis. Free Radic Biol Med 33:575-586 (Pubitemid 35245829)
-
(2002)
Free Radical Biology and Medicine
, vol.33
, Issue.5
, pp. 575-586
-
-
Sohal, R.S.1
Mockett, R.J.2
Orr, W.C.3
-
71
-
-
61449244533
-
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
-
Soukas AA, Kane EA, Carr CE et al (2009) Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev 23:496-511
-
(2009)
Genes Dev
, vol.23
, pp. 496-511
-
-
Soukas, A.A.1
Kane, E.A.2
Carr, C.E.3
-
72
-
-
0024452528
-
The pharmacology of dichloroacetate
-
Stacpoole PW (1989) The pharmacology of dichloroacetate. Metabolism 38:1124-1144
-
(1989)
Metabolism
, vol.38
, pp. 1124-1144
-
-
Stacpoole, P.W.1
-
73
-
-
0026448257
-
A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults
-
The Dichloroacetate-Lactic Acidosis Study Group
-
Stacpoole PW, Wright EC, Baumgartner TG et al (1992) A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group. N Engl J Med 327:1564-1569
-
(1992)
N Engl J Med
, vol.327
, pp. 1564-1569
-
-
Stacpoole, P.W.1
Wright, E.C.2
Baumgartner, T.G.3
-
75
-
-
74849137483
-
Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo
-
Sun RC, Fadia M, Dahlstrom JE et al (2010) Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo. Breast Cancer Res Treat 120:253-260
-
(2010)
Breast Cancer Res Treat
, vol.120
, pp. 253-260
-
-
Sun, R.C.1
Fadia, M.2
Dahlstrom, J.E.3
-
76
-
-
39149121832
-
Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes
-
Sutphin GL, Kaeberlein M (2008) Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes. Exp Gerontol 43:130-135
-
(2008)
Exp Gerontol
, vol.43
, pp. 130-135
-
-
Sutphin, G.L.1
Kaeberlein, M.2
-
77
-
-
0035005609
-
Dichloroacetate improves cardiac efficiency after ischemia independent of changes in mitochondrial proton leak
-
Taniguchi M, Wilson C, Hunter CA et al (2001) Dichloroacetate improves cardiac efficiency after ischemia independent of changes in mitochondrial proton leak. Am J Physiol Heart Circ Physiol 280:H1762-H1769
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Taniguchi, M.1
Wilson, C.2
Hunter, C.A.3
-
78
-
-
64949168686
-
Can we develop genetically tractable models to assess healthspan (rather than life span) in animal models?
-
Tatar M (2009) Can we develop genetically tractable models to assess healthspan (rather than life span) in animal models? J Gerontol A Biol Sci Med Sci 64:161-163
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, pp. 161-163
-
-
Tatar, M.1
-
79
-
-
29144458899
-
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
-
DOI 10.1073/pnas.0508886102
-
Trifunovic A, Hansson A, Wredenberg A et al (2005) Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proc Natl Acad Sci USA 102:17993-17998 (Pubitemid 41798490)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.50
, pp. 17993-17998
-
-
Trifunovic, A.1
Hansson, A.2
Wredenberg, A.3
Rovio, A.T.4
Dufour, E.5
Khvorostov, I.6
Spelbrink, J.N.7
Wibom, R.8
Jacobs, H.T.9
Larsson, N.-G.10
-
80
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
Turrens JF (2003) Mitochondrial formation of reactive oxygen species. J Physiol 552:335-344
-
(2003)
J Physiol
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
81
-
-
61449184625
-
Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans
-
Van Raamsdonk JM, Hekimi S (2009) Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans. PLoS Genet 5:e1000361
-
(2009)
PLoS Genet
, vol.5
-
-
Van Raamsdonk, J.M.1
Hekimi, S.2
-
82
-
-
55849101681
-
Fat metabolism links germline stem cells and longevity in C. elegans
-
Wang MC, O'Rourke EJ, Ruvkun G (2008) Fat metabolism links germline stem cells and longevity in C. elegans. Science 322:957-960
-
(2008)
Science
, vol.322
, pp. 957-960
-
-
Wang, M.C.1
O'Rourke, E.J.2
Ruvkun, G.3
-
83
-
-
0026554863
-
Counting target molecules by exponential polymerase chain reaction: Copy number of mitochondrial DNA in rat tissues
-
Wiesner RJ, Ruegg JC, Morano I (1992) Counting target molecules by exponential polymerase chain reaction: copy number of mitochondrial DNA in rat tissues. Biochem Biophys Res Commun 183:553-559
-
(1992)
Biochem Biophys Res Commun
, vol.183
, pp. 553-559
-
-
Wiesner, R.J.1
Ruegg, J.C.2
Morano, I.3
-
84
-
-
33746787082
-
-
World Health Organization WHO document WHO/SDE/WSH/05.08/121
-
World Health Organization (2005) Dichloroacetic acid in drinking-water. WHO document WHO/SDE/WSH/05.08/121
-
(2005)
Dichloroacetic Acid in Drinking-water
-
-
-
85
-
-
33644958967
-
Visualizing hidden heterogeneity in isogenic populations of C. elegans
-
Wu D, Rea SL, Yashin AI et al (2006) Visualizing hidden heterogeneity in isogenic populations of C. elegans. Exp Gerontol 41:261-270
-
(2006)
Exp Gerontol
, vol.41
, pp. 261-270
-
-
Wu, D.1
Rea, S.L.2
Yashin, A.I.3
-
86
-
-
0032573066
-
Mitochondrial adenine nucleotide translocase is modified oxidatively during aging
-
Yan LJ, Sohal RS (1998) Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc Natl Acad Sci USA 95:12896-12901
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12896-12901
-
-
Yan, L.J.1
Sohal, R.S.2
-
87
-
-
77949425398
-
Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans
-
Yen K, Mobbs CV (2010) Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans. Age 32:39-49
-
(2010)
Age
, vol.32
, pp. 39-49
-
-
Yen, K.1
Mobbs, C.V.2
|