Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: Von Hippel-Lindau disease and HIF-2α gain-of-function mutation

FASEB Journal

Volumn 25, Issue 6, 2011, Pages 2001-2011

  Formenti, Federico ^a,h   Beer, Philip A ^c   Croft, Quentin P P ^a   Dorrington, Keith L ^a   Gale, Daniel P ^d   Lappin, Terence R J ^e   Lucas, Guy S ^f   Maher, Eamonn R ^g   Maxwell, Patrick H ^d   McMullin, Mary F ^e   O'Connor, David F ^a   Percy, Melanie J ^e   Pugh, Christopher W ^b   Ratcliffe, Peter J ^b   Smith, Thomas G ^a   Talbot, Nick P ^a   Robbins, Peter A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^f MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^g UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^h UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Metabolism; Polycythemia; Pulmonary hypertension; Ventilation

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 2ALPHA;

ARTICLE; CARDIOPULMONARY FUNCTION; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GAIN OF FUNCTION MUTATION; GENETIC ASSOCIATION; HETEROZYGOTE; HUMAN; MALE; PHENOTYPE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; TACHYCARDIA; VON HIPPEL LINDAU DISEASE;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARBON DIOXIDE; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; CASE-CONTROL STUDIES; EXERCISE TEST; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MUTATION; OXYGEN; VON HIPPEL-LINDAU DISEASE;

EID: 79957901942     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-177378     Document Type: Article

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