메뉴 건너뛰기




Volumn 3, Issue 7, 2006, Pages 1178-1186

Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; VON HIPPEL LINDAU PROTEIN; CARBON DIOXIDE; FRUCTOSE BISPHOSPHATE ALDOLASE; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; OXYGEN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN; VHL PROTEIN, HUMAN;

EID: 33746398489     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0030290     Document Type: Article
Times cited : (162)

References (44)
  • 1
    • 8344237449 scopus 로고    scopus 로고
    • Hydroxylation of HIF-1: Oxygen sensing at the molecular level
    • Bethesda
    • Semenza GL (2004) Hydroxylation of HIF-1: Oxygen sensing at the molecular level. Physiology (Bethesda) 19: 176-182.
    • (2004) Physiology , vol.19 , pp. 176-182
    • Semenza, G.L.1
  • 2
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell P, Wiesener M, Chang G, Clifford S, Vaux E, et al. (1999) The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399: 271-275.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.1    Wiesener, M.2    Chang, G.3    Clifford, S.4    Vaux, E.5
  • 3
    • 0033776536 scopus 로고    scopus 로고
    • Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
    • Ohh M, Park CW, Ivan M, Hoffman MA, Kim TY, et al. (2000) Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat Cell Biol 2: 423-427.
    • (2000) Nat Cell Biol , vol.2 , pp. 423-427
    • Ohh, M.1    Park, C.W.2    Ivan, M.3    Hoffman, M.A.4    Kim, T.Y.5
  • 6
    • 2642515744 scopus 로고    scopus 로고
    • HIF at the crossroads between ischemia and carcinogenesis
    • Paul SA, Simons JW, Mabjeesh NJ (2004) HIF at the crossroads between ischemia and carcinogenesis. J Cell Physiol 200: 20-30.
    • (2004) J Cell Physiol , vol.200 , pp. 20-30
    • Paul, S.A.1    Simons, J.W.2    Mabjeesh, N.J.3
  • 8
    • 18744373593 scopus 로고    scopus 로고
    • Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
    • Ang S, Chen H, Hirota K, Gordeuk V, Jelinek J, et al. (2002) Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nat Genet 32: 614-621.
    • (2002) Nat Genet , vol.32 , pp. 614-621
    • Ang, S.1    Chen, H.2    Hirota, K.3    Gordeuk, V.4    Jelinek, J.5
  • 9
    • 0042744741 scopus 로고    scopus 로고
    • Chuvash-type congenital polycythemia in 4 families of Asian and Western European ancestry
    • Percy MJ, McMullin MF, Jowitt SN, Potter M, Treacy M, et al. (2003) Chuvash-type congenital polycythemia in 4 families of Asian and Western European ancestry. Blood 102: 1097-1099.
    • (2003) Blood , vol.102 , pp. 1097-1099
    • Percy, M.J.1    McMullin, M.F.2    Jowitt, S.N.3    Potter, M.4    Treacy, M.5
  • 10
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 11
    • 0019958152 scopus 로고
    • A prediction-correction scheme for forcing alveolar gases along certain time courses
    • Robbins PA, Swanson GD, Howson MG (1982) A prediction-correction scheme for forcing alveolar gases along certain time courses. J Appl Physiol 52: 1353-1357.
    • (1982) J Appl Physiol , vol.52 , pp. 1353-1357
    • Robbins, P.A.1    Swanson, G.D.2    Howson, M.G.3
  • 12
    • 0002021436 scopus 로고
    • The properties of a turbine device for measuring respiratory volumes in man
    • Howson MG, Khamnei S, O'Connor DF, Robbins PA (1986) The properties of a turbine device for measuring respiratory volumes in man. J Physiol 382: 12P.
    • (1986) J Physiol , vol.382
    • Howson, M.G.1    Khamnei, S.2    O'Connor, D.F.3    Robbins, P.A.4
  • 13
    • 0021143486 scopus 로고
    • Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation
    • Yock PG, Popp RL (1984) Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation. Circulation 70: 657-662.
    • (1984) Circulation , vol.70 , pp. 657-662
    • Yock, P.G.1    Popp, R.L.2
  • 14
    • 14144253561 scopus 로고    scopus 로고
    • Two temporal components within the human pulmonary vascular response to ∼2 h of isocapnic hypoxia
    • Talbot NP, Balanos GM, Dorrington KL, Robbins PA (2005) Two temporal components within the human pulmonary vascular response to ∼2 h of isocapnic hypoxia. J Appl Physiol 98: 1125-1139.
    • (2005) J Appl Physiol , vol.98 , pp. 1125-1139
    • Talbot, N.P.1    Balanos, G.M.2    Dorrington, K.L.3    Robbins, P.A.4
  • 15
    • 0037377639 scopus 로고    scopus 로고
    • Human pulmonary vascular response to 4 h of hypercapnia and hypocapnia measured using Doppler echocardiography
    • Balanos GM, Talbot NP, Dorrington KL, Robbins PA (2003) Human pulmonary vascular response to 4 h of hypercapnia and hypocapnia measured using Doppler echocardiography. J Appl Physiol 94: 1543-1551.
    • (2003) J Appl Physiol , vol.94 , pp. 1543-1551
    • Balanos, G.M.1    Talbot, N.P.2    Dorrington, K.L.3    Robbins, P.A.4
  • 16
    • 3543120077 scopus 로고    scopus 로고
    • Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: A randomized, double-blind, placebo-controlled crossover trial
    • Ghofrani HA, Reichenberger F, Kohstall MG, Mrosek EH, Seeger T, et al. (2004) Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: A randomized, double-blind, placebo-controlled crossover trial. Ann Intern Med 141: 169-177.
    • (2004) Ann Intern Med , vol.141 , pp. 169-177
    • Ghofrani, H.A.1    Reichenberger, F.2    Kohstall, M.G.3    Mrosek, E.H.4    Seeger, T.5
  • 17
    • 0343619355 scopus 로고    scopus 로고
    • Stress doppler echocardiography for identification of susceptibility to high altitude pulmonary edema
    • Grunig E, Mereles D, Hildebrandt W, Swenson ER, Kubler W, et al. (2000) Stress doppler echocardiography for identification of susceptibility to high altitude pulmonary edema. J Am Coll Cardiol 35: 980-987.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 980-987
    • Grunig, E.1    Mereles, D.2    Hildebrandt, W.3    Swenson, E.R.4    Kubler, W.5
  • 18
    • 0025074664 scopus 로고
    • Estimation of pulmonary artery pressure by Doppler echocardiography in normal subjects made hypoxic
    • Peacock AJ, Challenor V, Sutherland G (1990) Estimation of pulmonary artery pressure by Doppler echocardiography in normal subjects made hypoxic. Respir Med 84: 335-337.
    • (1990) Respir Med , vol.84 , pp. 335-337
    • Peacock, A.J.1    Challenor, V.2    Sutherland, G.3
  • 19
    • 0033713243 scopus 로고    scopus 로고
    • Echocardiographic and invasive measurements of pulmonary artery pressure correlate closely at high altitude
    • Allemann Y, Sartori C, Lepori M, Pierre S, Melot C, et al. (2000) Echocardiographic and invasive measurements of pulmonary artery pressure correlate closely at high altitude. Am J Physiol Heart Circ Physiol 279: H2013-H2016.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Allemann, Y.1    Sartori, C.2    Lepori, M.3    Pierre, S.4    Melot, C.5
  • 20
    • 6344280687 scopus 로고    scopus 로고
    • New formula for predicting mean pulmonary artery pressure using systolic pulmonary artery pressure
    • Chemla D, Castelain V, Humbert M, Hebert JL, Simonneau G, et al. (2004) New formula for predicting mean pulmonary artery pressure using systolic pulmonary artery pressure. Chest 126: 1313-1317.
    • (2004) Chest , vol.126 , pp. 1313-1317
    • Chemla, D.1    Castelain, V.2    Humbert, M.3    Hebert, J.L.4    Simonneau, G.5
  • 21
    • 0023639981 scopus 로고
    • Operation Everest II: Elevated high-altitude pulmonary resistance unresponsive to oxygen
    • Groves BM, Reeves JT, Sutton JR, Wagner PD, Cymerman A, et al. (1987) Operation Everest II: Elevated high-altitude pulmonary resistance unresponsive to oxygen. J Appl Physiol 63: 521-530.
    • (1987) J Appl Physiol , vol.63 , pp. 521-530
    • Groves, B.M.1    Reeves, J.T.2    Sutton, J.R.3    Wagner, P.D.4    Cymerman, A.5
  • 22
    • 5344233478 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • Farber HW, Loscalzo J (2004) Pulmonary arterial hypertension. N Engl J Med 351: 1655-1665.
    • (2004) N Engl J Med , vol.351 , pp. 1655-1665
    • Farber, H.W.1    Loscalzo, J.2
  • 23
    • 2342631195 scopus 로고    scopus 로고
    • Congenital disorder of oxygen sensing: Association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors
    • Gordeuk VR, Sergueeva AI, Miasnikova GY, Okhotin D, Voloshin Y, et al. (2004) Congenital disorder of oxygen sensing: Association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood 103: 3924-3932.
    • (2004) Blood , vol.103 , pp. 3924-3932
    • Gordeuk, V.R.1    Sergueeva, A.I.2    Miasnikova, G.Y.3    Okhotin, D.4    Voloshin, Y.5
  • 24
    • 0000625749 scopus 로고
    • Physiological observations made on Pike's Peak, Colorado, with special reference to adaptation to low barometric pressure
    • Douglas CG, Haldane JS, Henderson Y, Schneider EC (1913) Physiological observations made on Pike's Peak, Colorado, with special reference to adaptation to low barometric pressure. Philos Trans R Soc Lond B Biol Sci B203:: 185-318.
    • (1913) Philos Trans R Soc Lond B Biol Sci , vol.B203 , pp. 185-318
    • Douglas, C.G.1    Haldane, J.S.2    Henderson, Y.3    Schneider, E.C.4
  • 26
    • 0038216727 scopus 로고    scopus 로고
    • Hypoxic respiratory response during acute stable hypocapnia
    • Corne S, Webster K, Younes M (2003) Hypoxic respiratory response during acute stable hypocapnia. Am J Respir Crit Care Med 167: 1193-1199.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1193-1199
    • Corne, S.1    Webster, K.2    Younes, M.3
  • 27
    • 0034832857 scopus 로고    scopus 로고
    • Unexplained pulmonary hypertension in chronic myeloproliferative disorders
    • Dingli D, Utz JP, Krowka MJ, Oberg AL, Tefferi A (2001) Unexplained pulmonary hypertension in chronic myeloproliferative disorders. Chest 120: 801-808.
    • (2001) Chest , vol.120 , pp. 801-808
    • Dingli, D.1    Utz, J.P.2    Krowka, M.J.3    Oberg, A.L.4    Tefferi, A.5
  • 28
    • 0026556146 scopus 로고
    • Vascular and cardiac reactivity in pulmonary hypertension due to chronic obstructive lung disease: Assessment with various oxygen concentrations
    • Saadjian A, Philip-Joet F, Levy S, Arnaud A (1992) Vascular and cardiac reactivity in pulmonary hypertension due to chronic obstructive lung disease: Assessment with various oxygen concentrations. Eur Respir J 5: 525-530.
    • (1992) Eur Respir J , vol.5 , pp. 525-530
    • Saadjian, A.1    Philip-Joet, F.2    Levy, S.3    Arnaud, A.4
  • 29
    • 0016749904 scopus 로고
    • Blunted hypoxic pulmonary vasoconstriction by increased lung vascular pressures
    • Benumof JL, Wahrenbrock EA (1975) Blunted hypoxic pulmonary vasoconstriction by increased lung vascular pressures. J Appl Physiol 38: 846-850.
    • (1975) J Appl Physiol , vol.38 , pp. 846-850
    • Benumof, J.L.1    Wahrenbrock, E.A.2
  • 30
    • 33751261878 scopus 로고    scopus 로고
    • Time-course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia
    • Dorrington KL, Clar C, Young JD, Jonas M, Tansley JG, et al. (1997) Time-course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia. Am J Physiol 273: H1126-H1134.
    • (1997) Am J Physiol , vol.273
    • Dorrington, K.L.1    Clar, C.2    Young, J.D.3    Jonas, M.4    Tansley, J.G.5
  • 31
    • 0020523407 scopus 로고
    • Polycythemia and the acute hypoxic response in awake rats following chronic hypoxia
    • Fried R, Meyrick B, Rabinovitch M, Reid L (1983) Polycythemia and the acute hypoxic response in awake rats following chronic hypoxia. J Appl Physiol 55: 1167-1172.
    • (1983) J Appl Physiol , vol.55 , pp. 1167-1172
    • Fried, R.1    Meyrick, B.2    Rabinovitch, M.3    Reid, L.4
  • 32
    • 0014594291 scopus 로고
    • Decreased ventilatory response to hypoxia during acute polycythemia in the calf
    • Bisgard GE, Alvarez HG, Grover RF (1969) Decreased ventilatory response to hypoxia during acute polycythemia in the calf. Respir Physiol 7: 369-382.
    • (1969) Respir Physiol , vol.7 , pp. 369-382
    • Bisgard, G.E.1    Alvarez, H.G.2    Grover, R.F.3
  • 33
    • 0014531810 scopus 로고
    • Ventilatory response to hypoxia in acutely polycythemic dogs
    • Eisele JH, Pegg J, Severinghaus JW (1969) Ventilatory response to hypoxia in acutely polycythemic dogs. J Appl Physiol 26: 757-759.
    • (1969) J Appl Physiol , vol.26 , pp. 757-759
    • Eisele, J.H.1    Pegg, J.2    Severinghaus, J.W.3
  • 34
    • 0033032642 scopus 로고    scopus 로고
    • Ventilatory effects of 8 hours of isocapnic hypoxia with and without beta-blockade in humans
    • Clar C, Dorrington KL, Robbins PA (1999) Ventilatory effects of 8 hours of isocapnic hypoxia with and without beta-blockade in humans. J Appl Physiol 86: 1897-1904.
    • (1999) J Appl Physiol , vol.86 , pp. 1897-1904
    • Clar, C.1    Dorrington, K.L.2    Robbins, P.A.3
  • 36
    • 0343471958 scopus 로고    scopus 로고
    • Sympathetic modulation of hypoxic pulmonary vasoconstriction in intact dogs
    • Brimioulle S, Vachiery J, Brichant J, Delcroix M, Lejeune P, et al. (1997) Sympathetic modulation of hypoxic pulmonary vasoconstriction in intact dogs. Cardiovasc Res 34: 384-392.
    • (1997) Cardiovasc Res , vol.34 , pp. 384-392
    • Brimioulle, S.1    Vachiery, J.2    Brichant, J.3    Delcroix, M.4    Lejeune, P.5
  • 37
    • 0021139723 scopus 로고
    • Chronic propranolol treatment decreases pulmonary artery pressure in conscious dogs
    • Voelkel NF, Walker BR, Reeves JT (1984) Chronic propranolol treatment decreases pulmonary artery pressure in conscious dogs. Clin Physiol Biochem 2: 176-183.
    • (1984) Clin Physiol Biochem , vol.2 , pp. 176-183
    • Voelkel, N.F.1    Walker, B.R.2    Reeves, J.T.3
  • 38
    • 0037154262 scopus 로고    scopus 로고
    • Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
    • U S A
    • Kline DD, Peng YJ, Manalo DJ, Semenza GL, Prabhakar NR (2002) Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. Proc Natl Acad Sci U S A 99: 821-826.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 821-826
    • Kline, D.D.1    Peng, Y.J.2    Manalo, D.J.3    Semenza, G.L.4    Prabhakar, N.R.5
  • 39
    • 0033104847 scopus 로고    scopus 로고
    • Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
    • Yu AY, Shimoda LA, Iyer NV, Huso DL, Sun X, et al. (1999) Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. J Clin Invest 103: 691-696.
    • (1999) J Clin Invest , vol.103 , pp. 691-696
    • Yu, A.Y.1    Shimoda, L.A.2    Iyer, N.V.3    Huso, D.L.4    Sun, X.5
  • 41
    • 85047691081 scopus 로고    scopus 로고
    • Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
    • Brusselmans K, Compernolle V, Tjwa M, Wiesener MS, Maxwell PH, et al. (2003) Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. J Clin Invest 111: 1519-1527.
    • (2003) J Clin Invest , vol.111 , pp. 1519-1527
    • Brusselmans, K.1    Compernolle, V.2    Tjwa, M.3    Wiesener, M.S.4    Maxwell, P.H.5
  • 43
    • 0026577610 scopus 로고
    • Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia
    • Czyzyk-Krzeska MF, Bayliss DA, Lawson EE, Millhorn DE (1992) Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia. J Neurochem 58: 1538-1546.
    • (1992) J Neurochem , vol.58 , pp. 1538-1546
    • Czyzyk-Krzeska, M.F.1    Bayliss, D.A.2    Lawson, E.E.3    Millhorn, D.E.4
  • 44
    • 27644520812 scopus 로고    scopus 로고
    • Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies
    • Soliz J, Joseph V, Soulage C, Becskei C, Vogel J, et al. (2005) Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies. J Physiol 568: 559-571.
    • (2005) J Physiol , vol.568 , pp. 559-571
    • Soliz, J.1    Joseph, V.2    Soulage, C.3    Becskei, C.4    Vogel, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.