Novel strategies for drug discovery based on intrinsically disordered proteins (IDPs)

International Journal of Molecular Sciences

Volumn 12, Issue 5, 2011, Pages 3205-3219

  Wang, Jihua ^a,b   Cao, Zanxia ^a,b   Zhao, Liling ^a,b   Li, Shuqiang ^c  

^a Shandong Provincial Key Laboratory of Functional Macromolecular Biophysics   (China)

^b DEZHOU UNIVERSITY   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Drug discovery; Interaction networks; Intrinsically disordered proteins; Sequence characterizations; Structural characterizations

Indexed keywords

ALPHA SYNUCLEIN; EXIFONE; INTRINSICALLY DISORDERED PROTEIN; PROTEIN P53; ROTENONE; STRUCTURAL PROTEIN; TAU PROTEIN; UNCLASSIFIED DRUG;

ACETYLATION; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DESIGN; DRUG DEVELOPMENT; HUMAN; HYDROPHOBICITY; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE; POINT MUTATION; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; RAMAN SPECTROMETRY; REVIEW; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SYNAPSE VESICLE; THERMODYNAMICS; AMINO ACID SEQUENCE; CHEMISTRY; PROCEDURES; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; DRUG DISCOVERY; INTRINSICALLY DISORDERED PROTEINS; PROTEIN INTERACTION MAPS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, PROTEIN;

EID: 79957846007     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12053205     Document Type: Review

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