Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 45, 2006, Pages 16764-16769

  Crick, Scott L ^a   Jayaraman, Murali ^b,d   Frieden, Carl ^c   Wetzel, Ronald ^b,d   Pappu, Rohit V ^b  

^a WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^b UNIVERSITY OF TENNESSEE MEDICAL CENTER   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Chain collapse; Poor solvent

Indexed keywords

MONOMER; POLYGLUTAMINE; SOLVENT;

AQUEOUS SOLUTION; ARTICLE; BINDING KINETICS; DIFFUSION; FLUORESCENCE CORRELATION SPECTROSCOPY; HUNTINGTON CHOREA; HYDRODYNAMICS; HYDROPHOBICITY; MOLECULAR BIOLOGY; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; THERMODYNAMICS;

CIRCULAR DICHROISM; HUMANS; HUNTINGTON DISEASE; HYDROPHOBICITY; LINEAR MODELS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS; WATER;

EID: 33750934185     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0608175103     Document Type: Article

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