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Volumn 197, Issue , 2010, Pages 143-170

Viral vectors for gene transfer: Current status of gene therapeutics

Author keywords

Adeno associated virus; Gene therapy; Lentivirus; Production methods; Retrovirus; Safety considerations; Viral vectors

Indexed keywords

CELL RECEPTOR; DNA; LENTIVIRUS VECTOR; ONCORETROVIRUS VECTOR; PARVOVIRUS VECTOR; RETROVIRUS VECTOR; RNA; SELF INACTIVATING ONCORETROVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 77953251302     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-00477-3_5     Document Type: Review
Times cited : (91)

References (48)
  • 1
    • 0030773892 scopus 로고    scopus 로고
    • Coupled effects of polybrene and calf serum on the efficiency of retroviral transduction and the stability of retroviral vectors
    • Andreadis S, Palsson BO (1997) Coupled effects of polybrene and calf serum on the efficiency of retroviral transduction and the stability of retroviral vectors. Hum Gene Ther 8:285-291
    • (1997) Hum Gene Ther , vol.8 , pp. 285-291
    • Andreadis, S.1    Palsson, B.O.2
  • 2
    • 0030865201 scopus 로고    scopus 로고
    • Moloney murine leukemia virus-derived retroviral vectors decay intracellularly with a half-life in the range of 5.5 to 7.5 h
    • Andreadis ST, Brott D, Fuller AO, Palsson BO (1997) Moloney murine leukemia virus-derived retroviral vectors decay intracellularly with a half-life in the range of 5.5 to 7.5 h. J Virol 71:7541-7548
    • (1997) J Virol , vol.71 , pp. 7541-7548
    • Andreadis, S.T.1    Brott, D.2    Fuller, A.O.3    Palsson, B.O.4
  • 5
    • 44849130087 scopus 로고    scopus 로고
    • Genotoxicity in gene therapy: An account of vector integration and designer nucleases
    • Bohne J, Cathomen T (2008) Genotoxicity in gene therapy: an account of vector integration and designer nucleases. Curr Opin Mol Ther 10:214-223
    • (2008) Curr Opin Mol Ther , vol.10 , pp. 214-223
    • Bohne, J.1    Cathomen, T.2
  • 8
    • 0033054126 scopus 로고    scopus 로고
    • Hightiter recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type i vector expressing AAV-2 rep and cap
    • Conway J, Rhys C, Zolotukhin I, Zolotukhin S, Muzyczka N, Hayward G, Byrne B (1999) Hightiter recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 rep and cap. Gene Ther 6:986-993
    • (1999) Gene Ther , vol.6 , pp. 986-993
    • Conway, J.1    Rhys, C.2    Zolotukhin, I.3    Zolotukhin, S.4    Muzyczka, N.5    Hayward, G.6    Byrne, B.7
  • 9
    • 0035835599 scopus 로고    scopus 로고
    • Supplemental guidance on testing for replication-competent retrovirus in retroviral vector-based gene therapy products and during follow-up of patients in clinical trials using retroviral vectors
    • FDA
    • FDA (2001) Supplemental guidance on testing for replication-competent retrovirus in retroviral vector-based gene therapy products and during follow-up of patients in clinical trials using retroviral vectors. Hum Gene Ther 12:315-320
    • (2001) Hum Gene Ther , vol.12 , pp. 315-320
  • 10
    • 15744365969 scopus 로고    scopus 로고
    • Integration of retroviruses: A fine balance between efficiency and danger
    • Fischer A, Cavazzana-Calvo M (2005) Integration of retroviruses: a fine balance between efficiency and danger. PLoS Med 2:e10
    • (2005) PLoS Med , vol.2
    • Fischer, A.1    Cavazzana-Calvo, M.2
  • 12
    • 0001469617 scopus 로고    scopus 로고
    • Knipe DM, Howley PM (eds) Fields Virology, Lippincott, Philadelphia
    • Goff S (2001) Retroviridae: the retroviruses and theit replication. In: Knipe DM, Howley PM (eds) Fields Virology, vol 2. Lippincott, Philadelphia, pp 1871-1940
    • (2001) Retroviridae: The Retroviruses and Theit Replication , vol.2 , pp. 1871-1940
    • Goff, S.1
  • 13
    • 1542369977 scopus 로고    scopus 로고
    • From virus evolution to vector revolution: Use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy
    • Grimm D, Kay MA (2003) From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Curr Gene Ther 3:281-304
    • (2003) Curr Gene Ther , vol.3 , pp. 281-304
    • Grimm, D.1    Kay, M.A.2
  • 14
    • 0038150506 scopus 로고    scopus 로고
    • Helper virus-free, optically controllable, and twoplasmid- based production of adeno-associated virus vectors of serotypes 1 to 6
    • Grimm D, Kay MA, Kleinschmidt JA (2003) Helper virus-free, optically controllable, and twoplasmid- based production of adeno-associated virus vectors of serotypes 1 to 6. Mol Ther 7:839-850
    • (2003) Mol Ther , vol.7 , pp. 839-850
    • Grimm, D.1    Kay, M.A.2    Kleinschmidt, J.A.3
  • 15
    • 0032506752 scopus 로고    scopus 로고
    • Novel tools for production and purification of recombinant adenoassociated virus vectors
    • Grimm D, Kern A, Rittner K, Kleinschmidt JA (1998) Novel tools for production and purification of recombinant adenoassociated virus vectors. Hum Gene Ther 9:2745-2760
    • (1998) Hum Gene Ther , vol.9 , pp. 2745-2760
    • Grimm, D.1    Kern, A.2    Rittner, K.3    Kleinschmidt, J.A.4
  • 18
    • 0344442392 scopus 로고    scopus 로고
    • SsDNA-dependent colocalization of adeno-associated virus Rep and herpes simplex virus ICP8 in nuclear replication domains
    • Heilbronn R, Engstler M, Weger S, Krahn A, Schetter C, Boshart M (2003) ssDNA-dependent colocalization of adeno-associated virus Rep and herpes simplex virus ICP8 in nuclear replication domains. Nucleic Acids Res 31:6206-6213
    • (2003) Nucleic Acids Res , vol.31 , pp. 6206-6213
    • Heilbronn, R.1    Engstler, M.2    Weger, S.3    Krahn, A.4    Schetter, C.5    Boshart, M.6
  • 20
    • 59449108477 scopus 로고    scopus 로고
    • Gene therapy fulfilling its promise
    • Kohn DB, Candotti F (2009) Gene therapy fulfilling its promise. N Engl J Med 360:518-521
    • (2009) N Engl J Med , vol.360 , pp. 518-521
    • Kohn, D.B.1    Candotti, F.2
  • 23
    • 0037431266 scopus 로고    scopus 로고
    • Real-time quantitative reverse transcriptase-polymerase chain reaction as a method for determining lentiviral vector titers and measuring transgene expression
    • Lizee G, Aerts JL, Gonzales MI, Chinnasamy N, Morgan RA, Topalian SL (2003) Real-time quantitative reverse transcriptase-polymerase chain reaction as a method for determining lentiviral vector titers and measuring transgene expression. Hum Gene Ther 14:497-507
    • (2003) Hum Gene Ther , vol.14 , pp. 497-507
    • Lizee, G.1    Aerts, J.L.2    Gonzales, M.I.3    Chinnasamy, N.4    Morgan, R.A.5    Topalian, S.L.6
  • 25
    • 4644323951 scopus 로고    scopus 로고
    • State-of-the-art of the production of retroviral vectors
    • Merten OW (2004) State-of-the-art of the production of retroviral vectors. J Gene Med 6(Suppl 1): S105-124
    • (2004) J Gene Med , vol.6 , Issue.SUPPL. 1
    • Merten, O.W.1
  • 26
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller DG, Adam MA, Miller AD (1990) Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 10:4239-4242
    • (1990) Mol Cell Biol , vol.10 , pp. 4239-4242
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 27
    • 23844556421 scopus 로고    scopus 로고
    • Large-scale analysis of adeno-associated virus vector integration sites in normal human cells
    • Miller DG, Trobridge GD, Petek LM, Jacobs MA, Kaul R, Russell DW (2005) Large-scale analysis of adeno-associated virus vector integration sites in normal human cells. J Virol 79:11434-11442
    • (2005) J Virol , vol.79 , pp. 11434-11442
    • Miller, D.G.1    Trobridge, G.D.2    Petek, L.M.3    Jacobs, M.A.4    Kaul, R.5    Russell, D.W.6
  • 29
    • 33750624015 scopus 로고    scopus 로고
    • Cellculture assays reveal the importance of retroviral vector design for insertional genotoxicity
    • Modlich U, Bohne J, Schmidt M, von Kalle C, Knoss S, Schambach A, Baum C (2006) Cellculture assays reveal the importance of retroviral vector design for insertional genotoxicity. Blood 108:2545-2553
    • (2006) Blood , vol.108 , pp. 2545-2553
    • Modlich, U.1    Bohne, J.2    Schmidt, M.3    Von Kalle, C.4    Knoss, S.5    Schambach, A.6    Baum, C.7
  • 31
  • 34
    • 34447134838 scopus 로고    scopus 로고
    • Use of nonintegrating lentiviral vectors for gene therapy
    • Philpott NJ, Thrasher AJ (2007) Use of nonintegrating lentiviral vectors for gene therapy. Hum Gene Ther 18:483-489
    • (2007) Hum Gene Ther , vol.18 , pp. 483-489
    • Philpott, N.J.1    Thrasher, A.J.2
  • 36
    • 34248526597 scopus 로고    scopus 로고
    • Purification of retroviral vectors for clinical application: Biological implications and technological challenges
    • Rodrigues T, Carrondo MJ, Alves PM, Cruz PE (2007) Purification of retroviral vectors for clinical application: biological implications and technological challenges. J Biotechnol 127:520-541
    • (2007) J Biotechnol , vol.127 , pp. 520-541
    • Rodrigues, T.1    Carrondo, M.J.2    Alves, P.M.3    Cruz, P.E.4
  • 37
    • 0036713630 scopus 로고    scopus 로고
    • Titering lentiviral vectors: Comparison of DNA, RNA and marker expression methods
    • Sastry L, Johnson T, Hobson MJ, Smucker B, Cornetta K (2002) Titering lentiviral vectors: comparison of DNA, RNA and marker expression methods. Gene Ther 9:1155-1162
    • (2002) Gene Ther , vol.9 , pp. 1155-1162
    • Sastry, L.1    Johnson, T.2    Hobson, M.J.3    Smucker, B.4    Cornetta, K.5
  • 38
    • 20344394438 scopus 로고    scopus 로고
    • A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography
    • Segura MM, Kamen A, Trudel P, Garnier A (2005) A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography. Biotechnol Bioeng 90:391-404
    • (2005) Biotechnol Bioeng , vol.90 , pp. 391-404
    • Segura, M.M.1    Kamen, A.2    Trudel, P.3    Garnier, A.4
  • 39
    • 33645888418 scopus 로고    scopus 로고
    • Downstream processing of oncoretroviral and lentiviral gene therapy vectors
    • Segura MM, Kamen A, Garnier A (2006) Downstream processing of oncoretroviral and lentiviral gene therapy vectors. Biotechnol Adv 24:321-337
    • (2006) Biotechnol Adv , vol.24 , pp. 321-337
    • Segura, M.M.1    Kamen, A.2    Garnier, A.3
  • 40
    • 0036811528 scopus 로고    scopus 로고
    • Production of clinical-grade recombinant adeno-associated virus vectors
    • Snyder RO, Flotte TR (2002) Production of clinical-grade recombinant adeno-associated virus vectors. Curr Opin Biotechnol 13:418-423
    • (2002) Curr Opin Biotechnol , vol.13 , pp. 418-423
    • Snyder, R.O.1    Flotte, T.R.2
  • 42
    • 13644257036 scopus 로고    scopus 로고
    • Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines
    • Toublanc E, Benraiss A, Bonnin D, Blouin V, Brument N, Cartier N, Epstein AL, Moullier P, Salvetti A (2004) Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines. J Gene Med 6:555-564
    • (2004) J Gene Med , vol.6 , pp. 555-564
    • Toublanc, E.1    Benraiss, A.2    Bonnin, D.3    Blouin, V.4    Brument, N.5    Cartier, N.6    Epstein, A.L.7    Moullier, P.8    Salvetti, A.9
  • 43
    • 0036431701 scopus 로고    scopus 로고
    • Insect cells as a factory to produce adeno-associated virus type 2 vectors
    • Urabe M, Ding C, Kotin RM (2002) Insect cells as a factory to produce adeno-associated virus type 2 vectors. Hum Gene Ther 13:1935-1943
    • (2002) Hum Gene Ther , vol.13 , pp. 1935-1943
    • Urabe, M.1    Ding, C.2    Kotin, R.M.3
  • 45
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao X, Li J, Samulski RJ (1998) Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 72:2224-2232
    • (1998) J Virol , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 47
    • 19644381507 scopus 로고    scopus 로고
    • Production of recombinant adeno-associated virus vectors
    • Zolotukhin S (2005) Production of recombinant adeno-associated virus vectors. Hum Gene Ther 16:551-557
    • (2005) Hum Gene Ther , vol.16 , pp. 551-557
    • Zolotukhin, S.1


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