Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models

Gene Therapy

Volumn 15, Issue 19, 2008, Pages 1330-1343

  Lattanzi, W ^a   Parrilla, C ^a   Fetoni, A ^a   Logroscino, G ^a   Straface, G ^a   Pecorini, G ^a   Stigliano, E ^a   Tampieri, A ^b   Bedini, R ^c   Pecci, R ^c   Michetti, F ^a,d   Gambotto, A ^e   Robbins, P D ^e   Pola, E ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b CNR   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d Latium Musculoskeletal Tissue Bank   (Italy)

^e UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BIOMATERIAL; CELL PROTEIN; COLLAGEN; HYDROXYAPATITE; LIM MINERALIZATION PROTEIN 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOTRANSPLANTATION; BONE DEFECT; BONE DEVELOPMENT; BONE MINERALIZATION; BONE RADIOGRAPHY; CELL BASED GENE THERAPY; CONTROLLED STUDY; EX VIVO GENE TRANSFER; EXTRACELLULAR MATRIX; FRACTURE HEALING; GENE EXPRESSION; GENETIC TRANSDUCTION; HISTOLOGY; MALE; MANDIBLE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; PRIORITY JOURNAL; RAT; SKIN FIBROBLAST; THREE DIMENSIONAL IMAGING;

ADENOVIRIDAE; ANIMALS; BONE AND BONES; BONE DISEASES; FIBROBLASTS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; OSTEOGENESIS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE SCAFFOLDS; TOMOGRAPHY, X-RAY COMPUTED; TRANSDUCTION, GENETIC; TRANSPLANTATION, AUTOLOGOUS;

ANIMALIA; RATTUS; RODENTIA;

EID: 52049086443     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2008.116     Document Type: Article

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