-
1
-
-
0035475642
-
Dynamic mutations: A decade of unstable expanded repeats in human genetic disease
-
Richards,R.I. (2001) Dynamic mutations: a decade of unstable expanded repeats in human genetic disease. Hum. Mol. Genet., 10, 2187-2194.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2187-2194
-
-
Richards, R.I.1
-
2
-
-
0035800434
-
Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9
-
Liquori,C.L., Ricker,K., Moseley,M.L., Jacobsen,J.F., Kress,W., Naylor,S.L., Day,J.W. and Ranum,L.P. (2001) Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9. Science, 293, 864-867.
-
(2001)
Science
, vol.293
, pp. 864-867
-
-
Liquori, C.L.1
Ricker, K.2
Moseley, M.L.3
Jacobsen, J.F.4
Kress, W.5
Naylor, S.L.6
Day, J.W.7
Ranum, L.P.8
-
3
-
-
0026767610
-
Dynamic mutations: A new class of mutations causing human disease
-
Richards,R.I. and Sutherland,G.R. (1992) Dynamic mutations: a new class of mutations causing human disease. Cell, 70, 709-713.
-
(1992)
Cell
, vol.70
, pp. 709-713
-
-
Richards, R.I.1
Sutherland, G.R.2
-
4
-
-
0028873248
-
Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: Small pool PCR analyses
-
Monckton,D.G., Wong,L.-J.C., Ashizawa,T. and Caskey,C.T. (1995) Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses. Hum. Mol. Genet., 4, 1-8.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 1-8
-
-
Monckton, D.G.1
Wong, L.-J.C.2
Ashizawa, T.3
Caskey, C.T.4
-
5
-
-
0034641887
-
Dramatic mutation instability in HD mouse striatum: Does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
-
Kennedy,L. and Shelbourne,P.F. (2000) Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease? Hum. Mol. Genet., 9, 2539-2544.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2539-2544
-
-
Kennedy, L.1
Shelbourne, P.F.2
-
6
-
-
0032907359
-
Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients
-
Sato,T., Oyake,M., Nakamura,K., Nakao,K., Fukusima,Y., Onodera,O., Igarashi,S., Takano,H., Kikugawa,K., Ishida,Y. et al. (1999) Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients. Hum. Mol. Genet., 8, 99-106.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 99-106
-
-
Sato, T.1
Oyake, M.2
Nakamura, K.3
Nakao, K.4
Fukusima, Y.5
Onodera, O.6
Igarashi, S.7
Takano, H.8
Kikugawa, K.9
Ishida, Y.10
-
7
-
-
0030975726
-
Mosaicism of the CAG repeat in CNS tissue in relation to age at death in spinocerebellar ataxia type 1 and Machado-Joseph disease patients
-
Maciel,P., Lopes-Cendes,I., Kish,S., Sequeiros,J. and Rouleau,G.A. (1997) Mosaicism of the CAG repeat in CNS tissue in relation to age at death in spinocerebellar ataxia type 1 and Machado-Joseph disease patients. Am. J. Hum. Genet., 60, 993-996.
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 993-996
-
-
Maciel, P.1
Lopes-Cendes, I.2
Kish, S.3
Sequeiros, J.4
Rouleau, G.A.5
-
8
-
-
0032712586
-
n DNA repeat expansions in the sperm of two spinocerebellar ataxia type 7 males
-
n DNA repeat expansions in the sperm of two spinocerebellar ataxia type 7 males. Hum. Mol. Genet., 8, 2473-2478.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 2473-2478
-
-
Monckton, D.G.1
Cayuela, M.L.2
Gould, F.K.3
Brock, G.J.R.4
de Silva, R.5
Ashizawa, T.6
-
9
-
-
0027257735
-
Larger expansions of the CTG repeat in muscle compared to lymphocytes from patients with myotonic dystrophy
-
Anvret,M., Ahlberg,G., Grandell,U., Hedberg,B., Johnson,K. and Edstrom,L. (1993) Larger expansions of the CTG repeat in muscle compared to lymphocytes from patients with myotonic dystrophy. Hum. Mol. Genet., 2, 1397-1400.
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 1397-1400
-
-
Anvret, M.1
Ahlberg, G.2
Grandell, U.3
Hedberg, B.4
Johnson, K.5
Edstrom, L.6
-
10
-
-
0027716510
-
Somatic instability of CTG repeat in myotonic dystrophy
-
Ashizawa,T., Dubel,J.R. and Harati,Y. (1993) Somatic instability of CTG repeat in myotonic dystrophy. Neurology, 43, 2674-2678.
-
(1993)
Neurology
, vol.43
, pp. 2674-2678
-
-
Ashizawa, T.1
Dubel, J.R.2
Harati, Y.3
-
11
-
-
0027957470
-
Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes
-
Thornton,C.A., Johnson,K.J. and Moxley,R.T. (1994) Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes. Ann. Neurol., 35, 104-107.
-
(1994)
Ann. Neurol.
, vol.35
, pp. 104-107
-
-
Thornton, C.A.1
Johnson, K.J.2
Moxley, R.T.3
-
12
-
-
0346752132
-
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
-
Kennedy,L., Evans,E., Chen,C.M., Craven,L., Detloff,P.J., Ennis,M. and Shelbourne,P.F. (2003) Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis. Hum. Mol. Genet., 12, 3359-3367.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3359-3367
-
-
Kennedy, L.1
Evans, E.2
Chen, C.M.3
Craven, L.4
Detloff, P.J.5
Ennis, M.6
Shelbourne, P.F.7
-
13
-
-
0034329159
-
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
-
Gusella,J.F. and MacDonald,M.E. (2000) Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease. Nature Rev. Neurosci., 1, 109-115.
-
(2000)
Nature Rev. Neurosci.
, vol.1
, pp. 109-115
-
-
Gusella, J.F.1
MacDonald, M.E.2
-
14
-
-
0034622926
-
Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat
-
Mankodi,A., Logigian,E., Callahan,L., McClain,C., White,R., Henderson,D., Krym,M. and Thornton,C.A. (2000) Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat. Science, 289, 1769-1773.
-
(2000)
Science
, vol.289
, pp. 1769-1773
-
-
Mankodi, A.1
Logigian, E.2
Callahan, L.3
McClain, C.4
White, R.5
Henderson, D.6
Krym, M.7
Thornton, C.A.8
-
15
-
-
0030841672
-
Expansion of a CUG trinucleotide repeat in the 3′ untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts
-
Davis,B.M., McCurrach,M.E., Taneja,K.L., Singer,R.H. and Housman,D.E. (1997) Expansion of a CUG trinucleotide repeat in the 3′ untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts. Proc. Natl Acad. Sci. USA, 94, 7388-7393.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7388-7393
-
-
Davis, B.M.1
McCurrach, M.E.2
Taneja, K.L.3
Singer, R.H.4
Housman, D.E.5
-
16
-
-
0033120042
-
Sticky DNA: Self-association properties of long GAA·TTC repeats in R·R·Y triplex structures from Friedreich's ataxia
-
Sakamoto,N., Chastain,P.D., Parniewski,P., Ohshima,K., Pandolfo,M., Griffith,J.D. and Wells,R.D. (1999) Sticky DNA: self-association properties of long GAA·TTC repeats in R· R·Y triplex structures from Friedreich's ataxia. Mol. Cell, 3, 465-475.
-
(1999)
Mol. Cell
, vol.3
, pp. 465-475
-
-
Sakamoto, N.1
Chastain, P.D.2
Parniewski, P.3
Ohshima, K.4
Pandolfo, M.5
Griffith, J.D.6
Wells, R.D.7
-
17
-
-
0030845879
-
Trinucleotide repeat expansion at the myotonic dystrophy locus reduces expression of DMAHP
-
Klesert,T.R., Otten,A.D., Bird,T.D. and Tapscott,S.J. (1997) Trinucleotide repeat expansion at the myotonic dystrophy locus reduces expression of DMAHP. Nature Genet., 16, 402-406.
-
(1997)
Nature Genet.
, vol.16
, pp. 402-406
-
-
Klesert, T.R.1
Otten, A.D.2
Bird, T.D.3
Tapscott, S.J.4
-
18
-
-
0034639857
-
Understanding the molecular basis of fragile X syndrome
-
Jin,P. and Warren,S.T. (2000) Understanding the molecular basis of fragile X syndrome. Hum. Mol. Genet., 9, 901-908.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 901-908
-
-
Jin, P.1
Warren, S.T.2
-
19
-
-
0032900772
-
An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8)
-
Koob,M.D., Moseley,M.L., Schut,L.J., Benzow,K.A., Bird,T.D., Day,J.W. and Ranum,L.P. (1999) An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8). Nature Genet., 21, 379-384.
-
(1999)
Nature Genet.
, vol.21
, pp. 379-384
-
-
Koob, M.D.1
Moseley, M.L.2
Schut, L.J.3
Benzow, K.A.4
Bird, T.D.5
Day, J.W.6
Ranum, L.P.7
-
20
-
-
0033771685
-
Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10
-
Matsuura,T., Yamagata,T., Burgess,D.L., Rasmussen,A., Grewal,R.P., Watase,K., Khajavi,M., McCall,A.E., Davis,C.F., Zu,L. et al. (2000) Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10. Nature Genet., 26, 191-194.
-
(2000)
Nature Genet.
, vol.26
, pp. 191-194
-
-
Matsuura, T.1
Yamagata, T.2
Burgess, D.L.3
Rasmussen, A.4
Grewal, R.P.5
Watase, K.6
Khajavi, M.7
McCall, A.E.8
Davis, C.F.9
Zu, L.10
-
21
-
-
0037321290
-
Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum
-
Wheeler,V.C., Lebel,L.A., Vrbanac,V., Teed,A., Te Riele,H. and MacDonald,M.E. (2003) Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum. Hum. Mol. Genet., 12, 273-281.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 273-281
-
-
Wheeler, V.C.1
Lebel, L.A.2
Vrbanac, V.3
Teed, A.4
Te Riele, H.5
MacDonald, M.E.6
-
22
-
-
0031056685
-
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation
-
Mangiarini,L., Sathasivam,K., Mahal,A., Mott,R., Seller,M. and Bates,G.P. (1997) Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation. Nature Genet., 15, 197-200.
-
(1997)
Nature Genet.
, vol.15
, pp. 197-200
-
-
Mangiarini, L.1
Sathasivam, K.2
Mahal, A.3
Mott, R.4
Seller, M.5
Bates, G.P.6
-
23
-
-
0031827446
-
Somatic instability of the CTG repeat in mice transgenic for the myotonic dystrophy region is age dependent but not correlated to the relative intertissue transcription levels and proliferative capacities
-
Lia,A.S., Seznec,H., Hofmann Radvanyi,H., Radvanyi,F., Duros,C., Saquet,C., Blanche,M., Junien,C. and Gourdon,G. (1998) Somatic instability of the CTG repeat in mice transgenic for the myotonic dystrophy region is age dependent but not correlated to the relative intertissue transcription levels and proliferative capacities. Hum. Mol. Genet., 7, 1285-1291.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 1285-1291
-
-
Lia, A.S.1
Seznec, H.2
Hofmann Radvanyi, H.3
Radvanyi, F.4
Duros, C.5
Saquet, C.6
Blanche, M.7
Junien, C.8
Gourdon, G.9
-
24
-
-
0034639711
-
Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability
-
Fortune,M.T., Vassilopoulos,C., Coolbaugh,M.I., Siciliano,M.J. and Monckton,D.G. (2000) Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability. Hum. Mol. Genet., 9, 439-445.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 439-445
-
-
Fortune, M.T.1
Vassilopoulos, C.2
Coolbaugh, M.I.3
Siciliano, M.J.4
Monckton, D.G.5
-
25
-
-
0035311021
-
Mouse tissue culture models of unstable triplet repeats: In vitro selection for larger alleles, mutational expansion bias and tissue specificity, but no association with cell division rates
-
Gomes-Pereira,M., Fortune,M.T. and Monckton,D.G. (2001) Mouse tissue culture models of unstable triplet repeats: in vitro selection for larger alleles, mutational expansion bias and tissue specificity, but no association with cell division rates. Hum. Mol. Genet., 10, 845-854.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 845-854
-
-
Gomes-Pereira, M.1
Fortune, M.T.2
Monckton, D.G.3
-
26
-
-
0032708840
-
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice
-
Manley,K., Shirley,T.L., Flaherty,L. and Messer,A. (1999) Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice. Nature Genet., 23, 471-473.
-
(1999)
Nature Genet.
, vol.23
, pp. 471-473
-
-
Manley, K.1
Shirley, T.L.2
Flaherty, L.3
Messer, A.4
-
27
-
-
0037081784
-
(n) repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins
-
(n) repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins. Hum. Mol. Genet., 11, 191-198.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 191-198
-
-
vanDenBroek, W.J.1
Nelen, M.R.2
Wansink, D.G.3
Coerwinkel, M.M.4
te Riele, H.5
Groenen, P.J.6
Wieringa, B.7
-
28
-
-
0037543991
-
CTG repeat instability and size variation timing in DNA repair-deficient mice
-
Savouret,C., Brisson,E., Essers,J., Kanaar,R., Pastink,A., te Riele,H., Junien,C. and Gourdon,G. (2003) CTG repeat instability and size variation timing in DNA repair-deficient mice. EMBO J., 22, 2264-2273.
-
(2003)
EMBO J.
, vol.22
, pp. 2264-2273
-
-
Savouret, C.1
Brisson, E.2
Essers, J.3
Kanaar, R.4
Pastink, A.5
te Riele, H.6
Junien, C.7
Gourdon, G.8
-
29
-
-
17944402318
-
Hydrogen peroxide induced mutations at the HPRT locus in primary human T-lymphocytes
-
Diaz-Llera,S., Podlutsky,A., Osterholm,A.M., Hou,S.M. and Lambert,B. (2000) Hydrogen peroxide induced mutations at the HPRT locus in primary human T-lymphocytes. Mutat. Res., 469, 51-61.
-
(2000)
Mutat. Res.
, vol.469
, pp. 51-61
-
-
Diaz-Llera, S.1
Podlutsky, A.2
Osterholm, A.M.3
Hou, S.M.4
Lambert, B.5
-
30
-
-
0037427193
-
Characterization of trimethylpsoralen as a mutagen for mouse embryonic stem cells
-
Greber,B., Lehrach,H. and Himmelbauer,H. (2003) Characterization of trimethylpsoralen as a mutagen for mouse embryonic stem cells. Mutat. Res., 525, 67-76.
-
(2003)
Mutat. Res.
, vol.525
, pp. 67-76
-
-
Greber, B.1
Lehrach, H.2
Himmelbauer, H.3
-
31
-
-
0036942161
-
Transmission of mutations in the lacI transgene to the offspring of ENU-treated Big Blue male mice
-
Barnett,L.B., Tyl,R.W., Shane,B.S., Shelby,M.D. and Lewis,S.E. (2002) Transmission of mutations in the lacI transgene to the offspring of ENU-treated Big Blue male mice. Environ. Mol. Mutagen., 40, 251-257.
-
(2002)
Environ. Mol. Mutagen
, vol.40
, pp. 251-257
-
-
Barnett, L.B.1
Tyl, R.W.2
Shane, B.S.3
Shelby, M.D.4
Lewis, S.E.5
-
32
-
-
0028229761
-
Radiation induction of germline mutation at a hypervariable mouse minisatellite locus
-
Sadamoto,S., Suzuki,S., Kamiya,K., Kominami,R., Dohi,K. and Niwa,O. (1994) Radiation induction of germline mutation at a hypervariable mouse minisatellite locus. Int. J. Radiat. Biol., 65, 549-557.
-
(1994)
Int. J. Radiat. Biol.
, vol.65
, pp. 549-557
-
-
Sadamoto, S.1
Suzuki, S.2
Kamiya, K.3
Kominami, R.4
Dohi, K.5
Niwa, O.6
-
33
-
-
0029965291
-
Human minisatellite mutation-rate after the Chernobyl accident
-
Dubrova,Y.E., Nesterov,V.N., Krouchinsky,N.G., Ostapenko,V.A., Neumann,R., Neil,D.L. and Jeffreys,A.J. (1996) Human minisatellite mutation-rate after the Chernobyl accident. Nature, 380, 683-686.
-
(1996)
Nature
, vol.380
, pp. 683-686
-
-
Dubrova, Y.E.1
Nesterov, V.N.2
Krouchinsky, N.G.3
Ostapenko, V.A.4
Neumann, R.5
Neil, D.L.6
Jeffreys, A.J.7
-
34
-
-
0242548492
-
Germline mutation induction at mouse repeat DNA loci by chemical mutagens
-
Vilarino-Guell,C., Smith,A.G. and Dubrova,Y.E. (2003) Germline mutation induction at mouse repeat DNA loci by chemical mutagens. Mutat. Res., 526, 63-73.
-
(2003)
Mutat. Res.
, vol.526
, pp. 63-73
-
-
Vilarino-Guell, C.1
Smith, A.G.2
Dubrova, Y.E.3
-
35
-
-
0031054076
-
Hypermutable myotonic dystrophy CTG repeats in transgenic mice
-
Monckton,D.G., Coolbaugh,M.I., Ashizawa,K., Siciliano,M.J. and Caskey,C.T. (1997) Hypermutable myotonic dystrophy CTG repeats in transgenic mice. Nature Genet., 15, 193-196.
-
(1997)
Nature Genet.
, vol.15
, pp. 193-196
-
-
Monckton, D.G.1
Coolbaugh, M.I.2
Ashizawa, K.3
Siciliano, M.J.4
Caskey, C.T.5
-
36
-
-
0030586908
-
Instability of the expanded (CTG)n repeats in the myotonin protein kinase gene in cultured lymphoblastoid cell lines from patients with myotonic dystrophy
-
Ashizawa,T., Monckton,D.G., Vaishnav,S., Patel,B.J., Voskova,A. and Caskey,C.T. (1996) Instability of the expanded (CTG)n repeats in the myotonin protein kinase gene in cultured lymphoblastoid cell lines from patients with myotonic dystrophy. Genomics, 36, 47-53.
-
(1996)
Genomics
, vol.36
, pp. 47-53
-
-
Ashizawa, T.1
Monckton, D.G.2
Vaishnav, S.3
Patel, B.J.4
Voskova, A.5
Caskey, C.T.6
-
37
-
-
0033533725
-
Caffeine inhibits the checkpoint kinase ATM
-
Blasina,A., Price,B.D., Turenne,G.A. and McGowan,C.H. (1999) Caffeine inhibits the checkpoint kinase ATM. Curr. Biol., 9, 1135-1138.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1135-1138
-
-
Blasina, A.1
Price, B.D.2
Turenne, G.A.3
McGowan, C.H.4
-
38
-
-
0001406666
-
Detection of carcinogens as mutagens in the Salmonella/microsome test: Assay of 300 chemicals
-
McCann,J., Choi,E., Yamasaki,E. and Ames,B.N. (1975) Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals. Proc. Natl Acad. Sci. USA, 72, 5135-5139.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 5135-5139
-
-
McCann, J.1
Choi, E.2
Yamasaki, E.3
Ames, B.N.4
-
39
-
-
0034646080
-
Microsatellite instability induced by hydrogen peroxide in Escherichia coli
-
Jackson,A.L. and Loeb,L.A. (2000) Microsatellite instability induced by hydrogen peroxide in Escherichia coli. Mutat. Res., 447, 187-198.
-
(2000)
Mutat. Res.
, vol.447
, pp. 187-198
-
-
Jackson, A.L.1
Loeb, L.A.2
-
40
-
-
0016190692
-
Rhodamine 6G. A potent inhibitor of mitochondrial oxidative phosphorylation
-
Gear,A.R. (1974) Rhodamine 6G. A potent inhibitor of mitochondrial oxidative phosphorylation. J. Biol. Chem., 249, 3628-3637.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 3628-3637
-
-
Gear, A.R.1
-
41
-
-
0032530557
-
Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection
-
Ruschoff,J., Wallinger,S., Dietmaier,W., Bocker,T., Brockhoff,G., Hofstadter,F. and Fishel,R. (1998) Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection. Proc. Natl Acad. Sci. USA, 95, 11301-11306.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11301-11306
-
-
Ruschoff, J.1
Wallinger, S.2
Dietmaier, W.3
Bocker, T.4
Brockhoff, G.5
Hofstadter, F.6
Fishel, R.7
-
42
-
-
0033628701
-
Topoisomerase II as a target for anticancer drugs: When enzymes stop being nice
-
Fortune,J.M. and Osheroff,N. (2000) Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice. Prog. Nucleic Acid Res. Mol. Biol., 64, 221-253.
-
(2000)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.64
, pp. 221-253
-
-
Fortune, J.M.1
Osheroff, N.2
-
43
-
-
0028151343
-
Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann,R., Li,E. and Jaenisch,R. (1994) Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc. Natl Acad. Sci. USA, 91, 11797-11801.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11797-11801
-
-
Juttermann, R.1
Li, E.2
Jaenisch, R.3
-
44
-
-
0035400747
-
Imbalanced DNA synthesis induced by cytosine arabinoside and fludarabine in human leukemia cells
-
Carbone,G.M., Catapano,C.V. and Fernandes,D.J. (2001) Imbalanced DNA synthesis induced by cytosine arabinoside and fludarabine in human leukemia cells. Biochem. Pharmacol., 62, 101-110.
-
(2001)
Biochem. Pharmacol.
, vol.62
, pp. 101-110
-
-
Carbone, G.M.1
Catapano, C.V.2
Fernandes, D.J.3
-
45
-
-
0031984489
-
Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients
-
Martorell,L., Monckton,D.G., Gamez,J., Johnson,K.J., Gich,I., Lopez de Munain,A. and Baiget,M. (1998) Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients. Hum. Mol. Genet., 7, 307-312.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 307-312
-
-
Martorell, L.1
Monckton, D.G.2
Gamez, J.3
Johnson, K.J.4
Gich, I.5
Lopez de Munain, A.6
Baiget, M.7
-
46
-
-
0026457624
-
The correlation of age of onset with CTG trinucleotide repeat amplification in myotonic dystrophy
-
Hunter,A., Tsilfidis,C., Mettler,G., Jacob,P., Mahadevan,M., Surh,L. and Korneluk,R. (1992) The correlation of age of onset with CTG trinucleotide repeat amplification in myotonic dystrophy. J. Med. Genet., 29, 774-779.
-
(1992)
J. Med. Genet.
, vol.29
, pp. 774-779
-
-
Hunter, A.1
Tsilfidis, C.2
Mettler, G.3
Jacob, P.4
Mahadevan, M.5
Surh, L.6
Korneluk, R.7
-
47
-
-
0035311419
-
Mitotic drive of expanded CTG repeats in myotonic dystrophy type 1 (DM1)
-
Khajavi,M., Tari,A.M., Patel,N.B., Tsuji,K., Siwak,D.R., Meistrich,M.L., Terry,N.H. and Ashizawa,T. (2001) Mitotic drive of expanded CTG repeats in myotonic dystrophy type 1 (DM1). Hum. Mol. Genet., 10, 855-863.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 855-863
-
-
Khajavi, M.1
Tari, A.M.2
Patel, N.B.3
Tsuji, K.4
Siwak, D.R.5
Meistrich, M.L.6
Terry, N.H.7
Ashizawa, T.8
-
48
-
-
0035501562
-
Caffeine and the G2/M block override: A concept resulting from a misleading cell kinetic delay, independent of functional p53
-
Deplanque,G., Ceraline,J., Mah-Becherel,M.C., Cazenave,J.P., Bergerat,J.P. and Klein-Soyer,C. (2001) Caffeine and the G2/M block override: a concept resulting from a misleading cell kinetic delay, independent of functional p53. Int. J. Cancer, 94, 363-369.
-
(2001)
Int. J. Cancer
, vol.94
, pp. 363-369
-
-
Deplanque, G.1
Ceraline, J.2
Mah-Becherel, M.C.3
Cazenave, J.P.4
Bergerat, J.P.5
Klein-Soyer, C.6
-
49
-
-
0030935386
-
DNA polymerase delta is required for human mismatch repair in vitro
-
Longley,M.J., Pierce,A.J. and Modrich,P. (1997) DNA polymerase delta is required for human mismatch repair in vitro. J. Biol. Chem., 272, 10917-10921.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10917-10921
-
-
Longley, M.J.1
Pierce, A.J.2
Modrich, P.3
-
50
-
-
0027333102
-
Various inhibitors of DNA topoisomerases diminish repair-specific DNA incision in UV-irradiated human fibroblasts
-
Thielmann,H.W., Popanda,O., Gersbach,H. and Gilberg,F. (1993) Various inhibitors of DNA topoisomerases diminish repair-specific DNA incision in UV-irradiated human fibroblasts. Carcinogenesis, 14, 2341-2351.
-
(1993)
Carcinogenesis
, vol.14
, pp. 2341-2351
-
-
Thielmann, H.W.1
Popanda, O.2
Gersbach, H.3
Gilberg, F.4
-
51
-
-
3042715550
-
The unique alteration of electrophoretic mobility of fragile-X-expanded fragments in the presence of ethidium bromide
-
S016895259601054
-
Cummins,J.H. (1997) The unique alteration of electrophoretic mobility of fragile-X-expanded fragments in the presence of ethidium bromide. Tech. Tips Online, S016895259601054.
-
(1997)
Tech. Tips Online
-
-
Cummins, J.H.1
-
52
-
-
0029883805
-
Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci
-
Pearson,C.E. and Sinden,R.R. (1996) Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci. Biochemistry, 35, 5041-5053.
-
(1996)
Biochemistry
, vol.35
, pp. 5041-5053
-
-
Pearson, C.E.1
Sinden, R.R.2
-
53
-
-
0016756802
-
Ethidium bromide as an uncoupler of oxidative phosphorylation
-
Miko,M. and Chance,B. (1975) Ethidium bromide as an uncoupler of oxidative phosphorylation. FEBS Lett., 54, 347-352.
-
(1975)
FEBS Lett.
, vol.54
, pp. 347-352
-
-
Miko, M.1
Chance, B.2
-
54
-
-
0036082617
-
Oxidative stress inactivates the human DNA mismatch repair system
-
Chang,C.L., Marra,G., Chauhan,D.P., Ha,H.T., Chang,D.K., Ricciardiello,L., Randolph,A., Carethers,J.M. and Boland,C.R. (2002) Oxidative stress inactivates the human DNA mismatch repair system. Am. J. Physiol. Cell Physiol., 283, C148-C154.
-
(2002)
Am. J. Physiol. Cell Physiol.
, vol.283
-
-
Chang, C.L.1
Marra, G.2
Chauhan, D.P.3
Ha, H.T.4
Chang, D.K.5
Ricciardiello, L.6
Randolph, A.7
Carethers, J.M.8
Boland, C.R.9
-
55
-
-
0032522301
-
Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines
-
Chen,K.H., Yakes,F.M., Srivastava,D.K., Singhal,R.K., Sobol,R.W., Horton,J.K., Van Houten,B. and Wilson,S.H. (1998) Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. Nucleic Acids Res., 26, 2001-2007.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2001-2007
-
-
Chen, K.H.1
Yakes, F.M.2
Srivastava, D.K.3
Singhal, R.K.4
Sobol, R.W.5
Horton, J.K.6
Van Houten, B.7
Wilson, S.H.8
-
56
-
-
0032971232
-
Cis-acting modifiers of expanded CAG/CTG triplet repeat expandability: Associations with flanking GC content and proximity to CpG islands
-
Brock,G.J.R., Anderson,N.H. and Monckton,D.G. (1999) Cis-acting modifiers of expanded CAG/CTG triplet repeat expandability: associations with flanking GC content and proximity to CpG islands. Hum. Mol. Genet., 8, 1061-1067.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1061-1067
-
-
Brock, G.J.R.1
Anderson, N.H.2
Monckton, D.G.3
-
57
-
-
0030038519
-
Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: Effects on cell cycle and apoptosis
-
Shiff,S.J., Koutsos,M.I., Qiao,L. and Rigas,B. (1996) Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis. Exp. Cell Res., 222, 179-188.
-
(1996)
Exp. Cell Res.
, vol.222
, pp. 179-188
-
-
Shiff, S.J.1
Koutsos, M.I.2
Qiao, L.3
Rigas, B.4
-
58
-
-
0242607211
-
Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells
-
Yang,Z., Lau,R., Marcadier,J.L., Chitayat,D. and Pearson,C.E. (2003) Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells. Am. J. Hum. Genet., 73, 1092-1105.
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 1092-1105
-
-
Yang, Z.1
Lau, R.2
Marcadier, J.L.3
Chitayat, D.4
Pearson, C.E.5
-
59
-
-
17944404576
-
Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1
-
Pineiro,E., Fernandez-Lopez,L., Gamez,J., Marcos,R., Surralles,J. and Velazquez,A. (2003) Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1. Nucleic Acids Res., 31, 6733-6740.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6733-6740
-
-
Pineiro, E.1
Fernandez-Lopez, L.2
Gamez, J.3
Marcos, R.4
Surralles, J.5
Velazquez, A.6
-
60
-
-
0036713922
-
The GAA triplet-repeat sequence in Friedreich ataxia shows a high level of somatic instability in vivo, with a significant predilection for large contractions
-
Sharma,R., Bhatti,S., Gomez,M., Clark,R.M., Murray,C., Ashizawa,T. and Bidichandani,S.I. (2002) The GAA triplet-repeat sequence in Friedreich ataxia shows a high level of somatic instability in vivo, with a significant predilection for large contractions. Hum. Mol. Genet., 11, 2175-2187.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2175-2187
-
-
Sharma, R.1
Bhatti, S.2
Gomez, M.3
Clark, R.M.4
Murray, C.5
Ashizawa, T.6
Bidichandani, S.I.7
|