Comparative study on the bioactivation mechanisms and cytotoxicity of Te-phenyl-L-tellurocysteine, Se-Phenyl-L-selenocysteine, and S-Phenyl-L-cysteine

Chemical Research in Toxicology

Volumn 15, Issue 12, 2002, Pages 1610-1618

  Rooseboom, Martijn ^a   Vermeulen, Nico P E ^a   Durgut, Fatma ^a   Commandeur, Jan N M ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID OXIDASE; ANTIOXIDANT; BETA LYASE; CYSTEINE DERIVATIVE; CYTOCHROME P450 1A1; LYASE; PARACETAMOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SELENIUM DERIVATIVE; SELENIUM PHENYLSELENOCYSTEINE; SULFOPHENYLCYSTEINE; SULFUR DERIVATIVE; TELLURIUM DERIVATIVE; TELLURIUM PHENYLTELLUROCYSTEINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONJUGATION; CYTOTOXICITY; DRUG ACTIVITY; DRUG MECHANISM; ELIMINATION REACTION; ENZYME INHIBITION; EVALUATION; INTERMETHOD COMPARISON; LIVER CELL; METABOLITE; STATISTICAL SIGNIFICANCE; STRUCTURE ACTIVITY RELATION; TIME;

ANIMALS; BIOTRANSFORMATION; CYSTEINE; CYTOCHROME P-450 CYP1A1; D-AMINO-ACID OXIDASE; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTATHIONE TRANSFERASE; HEPATOCYTES; HUMANS; KIDNEY; KINETICS; LYASES; MALE; MICROSOMES, LIVER; ORGANOMETALLIC COMPOUNDS; RATS; RATS, WISTAR; SELENOCYSTEINE; TELLURIUM;

ILEX COOKII;

EID: 0036917330     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx020034f     Document Type: Article

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