An active site aromatic triad in escherichia coli DNA pol IV coordinates cell survival and mutagenesis in different DNA damaging agents

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Benson, Ryan W ^a   Norton, Matthew D ^a   Lin, Ida ^a   du Comb, William S ^a   Godoy, Veronica G ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL ENZYME; DNA POLYMERASE IV; MESYLIC ACID METHYL ESTER; UNCLASSIFIED DRUG; AMINO ACID; DINB PROTEIN, E COLI; DNA DIRECTED DNA POLYMERASE BETA; ESCHERICHIA COLI PROTEIN; NITROFURAL;

ALKYLATION; ALLELE; ARTICLE; BACTERIAL GENE; CATALYSIS; CELL SURVIVAL; DINB GENE; DNA DAMAGE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE EXPRESSION; MUTAGENESIS; NONHUMAN; POINT MUTATION; BIOCATALYSIS; CHEMISTRY; DNA REPAIR; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; HUMAN; METABOLISM; MICROBIAL VIABILITY; MUTATION; PHENOTYPE; PROTEIN MOTIF;

ESCHERICHIA COLI;

ALLELES; AMINO ACID MOTIFS; AMINO ACIDS; BIOCATALYSIS; CATALYTIC DOMAIN; DNA DAMAGE; DNA POLYMERASE BETA; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENE REGULATORY NETWORKS; GENES, BACTERIAL; HUMANS; METHYL METHANESULFONATE; MICROBIAL VIABILITY; MUTAGENESIS; MUTATION; NITROFURAZONE; PHENOTYPE; SOS RESPONSE (GENETICS);

EID: 79956137276     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019944     Document Type: Article

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