Pivotal role of the β-clamp in translesion DNA synthesis and mutagenesis in E. coli cells

DNA Repair

Volumn 1, Issue 9, 2002, Pages 703-708

  Becherel, Olivier J ^a,b   Fuchs, Robert P P ^a   Wagner, J ^a  

^a IRCAD   (France)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

DNA polymerases; Escherichia coli; Mutagenesis

Indexed keywords

BACTERIAL DNA; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE V, E COLI; ESCHERICHIA COLI PROTEIN; PROTEIN SUBUNIT; BACTERIAL ENZYME; DNA POLYMERASE;

ARTICLE; BIOSYNTHESIS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; MUTAGENESIS; MUTATION; PHYSIOLOGY; AMINO ACID SEQUENCE; BACTERIAL CELL; BACTERIAL MUTATION; BACTERIAL STRAIN; BINDING SITE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION;

DNA DAMAGE; DNA POLYMERASE BETA; DNA POLYMERASE II; DNA REPAIR; DNA REPLICATION; DNA, BACTERIAL; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MUTAGENESIS; MUTATION; PROTEIN SUBUNITS;

ESCHERICHIA COLI;

EID: 0037019606     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(02)00106-4     Document Type: Article

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14. The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication
15. UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli Pol V
16. In vivo stability of the Umu mutagenesis proteins: A major role for RecA
17. The ring-type polymerase sliding clamp family
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