Nucleotide Excision Repair Defect Influences Lethality and Mutagenicity Induced by Me-lex, a Sequence-Selective N3-Adenine Methylating Agent in the Absence of Base Excision Repair

Biochemistry

Volumn 43, Issue 19, 2004, Pages 5592-5599

  Monti, Paola ^a   Iannone, Raffaella ^a   Campomenosi, Paola ^b   Ciribilli, Yari ^a   Varadarajan, Sridhar ^c   Shah, Dharini ^c   Menichini, Paola ^a   Gold, Barry ^a   Fronza, Gilberto ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF INSUBRIA   (Italy)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS; DNA; ENZYMES; GENES; MUTAGENESIS; PROPANE; TOXICITY; YEAST;

BASE EXCISION REPAIR (BER); MUTATION FREQUENCY; MUTATION SPECTRUM; NUCLEOTIDE EXCISION REPAIR (NER);

BIOCHEMISTRY;

3 METHYLADENINE; AMIDE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA GLYCOSYLTRANSFERASE; GENE PRODUCT; ME LEX; PROTEIN MAG1; PROTEIN RAD14; PYRROLE DERIVATIVE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DNA METHYLATION; DNA REPAIR; ENZYME ACTIVITY; EXCISION REPAIR; GENE DELETION; GENE MUTATION; LETHALITY; MUTAGENICITY; MUTANT; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SHUTTLE VECTOR; WILD TYPE; YEAST;

ADENINE; BASE SEQUENCE; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; DNA REPAIR; GENE DELETION; GENE SILENCING; HUMANS; MUTAGENESIS; MUTAGENS; NETROPSIN; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

UNIDENTIFIED SHUTTLE VECTOR; ZIZIPHUS MAURITIANA;

EID: 2442616388     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035968x     Document Type: Article

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