메뉴 건너뛰기




Volumn 35, Issue 4, 2011, Pages 831-841

Elucidating biological risk factors in suicide: Role of protein kinase A

Author keywords

Animal models; Depression; G proteins; Human postmortem brain; Protein kinase A; Suicide

Indexed keywords

ADENYLATE CYCLASE; ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM ION; CLOZAPINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOCORTICOID; GUANINE NUCLEOTIDE BINDING PROTEIN; HALOPERIDOL; MITOGEN ACTIVATED PROTEIN KINASE; NEUROLEPTIC AGENT; RAP1 PROTEIN;

EID: 79956044874     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2010.08.025     Document Type: Short Survey
Times cited : (28)

References (160)
  • 1
    • 41449118891 scopus 로고    scopus 로고
    • Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinase
    • Abel T., Nguyen P.V. Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinase. Prog Brain Res 2008, 169:97-115.
    • (2008) Prog Brain Res , vol.169 , pp. 97-115
    • Abel, T.1    Nguyen, P.V.2
  • 2
    • 0028898390 scopus 로고
    • Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase
    • Adams J.A., McGlone M.L., Gibson R., Taylor S.S. Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase. Biochemistry 1995, 34:2447-2454.
    • (1995) Biochemistry , vol.34 , pp. 2447-2454
    • Adams, J.A.1    McGlone, M.L.2    Gibson, R.3    Taylor, S.S.4
  • 3
    • 0026456736 scopus 로고
    • Morphometric analysis of synaptic contacts in the anterior limbic cortex in the endogenous psychoses
    • Aganova E.A., Uranova N.A. Morphometric analysis of synaptic contacts in the anterior limbic cortex in the endogenous psychoses. Neurosci Behav Physiol 1992, 22:59-65.
    • (1992) Neurosci Behav Physiol , vol.22 , pp. 59-65
    • Aganova, E.A.1    Uranova, N.A.2
  • 4
    • 0037333670 scopus 로고    scopus 로고
    • Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study
    • Altamura A.C., Bassetti R., Bignotti S., Pioli R., Mundo E. Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study. Schizophr Res 2003, 60:47-55.
    • (2003) Schizophr Res , vol.60 , pp. 47-55
    • Altamura, A.C.1    Bassetti, R.2    Bignotti, S.3    Pioli, R.4    Mundo, E.5
  • 5
    • 1842334441 scopus 로고    scopus 로고
    • Anterograde transport of brain-derived neurotrophic factor and its role in the brain
    • Altar C.A., Cai N., Bliven T., Juhasz M., Conner J.M., Acheson A.L., et al. Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature 1997, 389:856-860.
    • (1997) Nature , vol.389 , pp. 856-860
    • Altar, C.A.1    Cai, N.2    Bliven, T.3    Juhasz, M.4    Conner, J.M.5    Acheson, A.L.6
  • 6
    • 0025195973 scopus 로고
    • The hippocampus and parahippocampus in schizophrenia, suicide, and control brains
    • Altshuler L.L., Casanova M.F., Goldberg T.E., Kleinman J.E. The hippocampus and parahippocampus in schizophrenia, suicide, and control brains. Arch Gen Psychiatry 1990, 47:1029-1034.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 1029-1034
    • Altshuler, L.L.1    Casanova, M.F.2    Goldberg, T.E.3    Kleinman, J.E.4
  • 8
    • 0031029294 scopus 로고    scopus 로고
    • Reduced G protein functions and immunoreactive levels in mononuclear leukocytes of patients with depression
    • Avissar S., Nechamkin Y., Roitman G., Schreiber G. Reduced G protein functions and immunoreactive levels in mononuclear leukocytes of patients with depression. Am J Psychiatry 1997, 154:211-217.
    • (1997) Am J Psychiatry , vol.154 , pp. 211-217
    • Avissar, S.1    Nechamkin, Y.2    Roitman, G.3    Schreiber, G.4
  • 9
    • 0031438050 scopus 로고    scopus 로고
    • BDNF enhances neuronal growth and synaptic activity in hippocampal cell cultures
    • Bartrup J.T., Moorman J.M., Newberry N.R. BDNF enhances neuronal growth and synaptic activity in hippocampal cell cultures. NeuroReport 1997, 8:3791-3794.
    • (1997) NeuroReport , vol.8 , pp. 3791-3794
    • Bartrup, J.T.1    Moorman, J.M.2    Newberry, N.R.3
  • 10
    • 0028491081 scopus 로고
    • The cAMP-dependent protein kinases and cAMP signal transduction
    • Beebe S.J. The cAMP-dependent protein kinases and cAMP signal transduction. Semin Cancer Biol 1994, 5:285-294.
    • (1994) Semin Cancer Biol , vol.5 , pp. 285-294
    • Beebe, S.J.1
  • 11
    • 4544249056 scopus 로고    scopus 로고
    • Suicide in the world: an epidemiological overview, 1959-2000
    • Dunitz, London, England, D. Wasserman (Ed.)
    • Bertolote J.M. Suicide in the world: an epidemiological overview, 1959-2000. Suicide: an Unnecessary Death 2001, 3-10. Dunitz, London, England. D. Wasserman (Ed.).
    • (2001) Suicide: an Unnecessary Death , pp. 3-10
    • Bertolote, J.M.1
  • 12
    • 0032904758 scopus 로고    scopus 로고
    • Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle
    • Bornfeldt K.E., Krebs E.G. Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle. Cell Signal 1999, 11:465-477.
    • (1999) Cell Signal , vol.11 , pp. 465-477
    • Bornfeldt, K.E.1    Krebs, E.G.2
  • 15
    • 0032525114 scopus 로고    scopus 로고
    • Defective motor behavior and neural gene expression in RIIβ-protein kinase A mutant mice
    • Brandon E.P., Logue S.F., Adams M.R., et al. Defective motor behavior and neural gene expression in RIIβ-protein kinase A mutant mice. J Neurosci 1998, 18:3639-3649.
    • (1998) J Neurosci , vol.18 , pp. 3639-3649
    • Brandon, E.P.1    Logue, S.F.2    Adams, M.R.3
  • 17
    • 0027520971 scopus 로고
    • Adolescent psychiatric inpatients' risk of suicide attempt at 6-month follow-up
    • Brent D., Kolko D., Wartella M., et al. Adolescent psychiatric inpatients' risk of suicide attempt at 6-month follow-up. J Am Acad Child Adolesc Psychiatry 1993, 32:95-105.
    • (1993) J Am Acad Child Adolesc Psychiatry , vol.32 , pp. 95-105
    • Brent, D.1    Kolko, D.2    Wartella, M.3
  • 18
    • 0029751944 scopus 로고    scopus 로고
    • Suicidal behavior runs in families: a controlled family study of adolescent suicide victims
    • Brent D., Bridge J., Johnson B., Connolly J. Suicidal behavior runs in families: a controlled family study of adolescent suicide victims. Arch Gen Psychiatry 1996, 53:1145-1149.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 1145-1149
    • Brent, D.1    Bridge, J.2    Johnson, B.3    Connolly, J.4
  • 19
    • 0033084222 scopus 로고    scopus 로고
    • Regulation of Ca2+ release by cAMP-dependent protein kinase: a mechanism for agonist-specific calcium signalingβ
    • Bugrim A.E. Regulation of Ca2+ release by cAMP-dependent protein kinase: a mechanism for agonist-specific calcium signalingβ. Cell Calcium 1999, 25:219-226.
    • (1999) Cell Calcium , vol.25 , pp. 219-226
    • Bugrim, A.E.1
  • 20
    • 0025221258 scopus 로고
    • Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides
    • Cadd G.G., Uhler M.D., McKnight G.S. Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides. J Biol Chem 1990, 265:19502-19506.
    • (1990) J Biol Chem , vol.265 , pp. 19502-19506
    • Cadd, G.G.1    Uhler, M.D.2    McKnight, G.S.3
  • 21
    • 0031888577 scopus 로고    scopus 로고
    • Physiological phosphorylation of protein kinase A at Thr-197 is by a protein kinase A kinase
    • Cauthron R.D., Carter K.B., Liauw S., Steinberg R.A. Physiological phosphorylation of protein kinase A at Thr-197 is by a protein kinase A kinase. Mol Cell Biol 1998, 18:1416-1423.
    • (1998) Mol Cell Biol , vol.18 , pp. 1416-1423
    • Cauthron, R.D.1    Carter, K.B.2    Liauw, S.3    Steinberg, R.A.4
  • 22
    • 0032544011 scopus 로고    scopus 로고
    • Phosphorylation and activation of cAMP dependent protein kinase by phosphoinositide-dependent protein kinase
    • Cheng X., Ma Y., Moore M., Hemmings B.A., Taylor S.S. Phosphorylation and activation of cAMP dependent protein kinase by phosphoinositide-dependent protein kinase. Proc Natl Acad Sci USA 1998, 95:9849-9854.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9849-9854
    • Cheng, X.1    Ma, Y.2    Moore, M.3    Hemmings, B.A.4    Taylor, S.S.5
  • 23
    • 15244352198 scopus 로고    scopus 로고
    • Emerging role for ERK as a key regulator of neuronal apoptosis
    • Cheung E.C., Slack R.S. Emerging role for ERK as a key regulator of neuronal apoptosis. Sci STKE 2004, 251:PE45.
    • (2004) Sci STKE , vol.251
    • Cheung, E.C.1    Slack, R.S.2
  • 26
    • 0011564219 scopus 로고
    • Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase
    • Clegg C.H., McKnight G.S. Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 1988, 85:3703-3707.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3703-3707
    • Clegg, C.H.1    McKnight, G.S.2
  • 27
    • 0037166333 scopus 로고    scopus 로고
    • CAMP-dependent protein kinase types I and II differentially regulate cAMP response element-mediated gene expression
    • Constantinescu A., Gordon A.S., Diamond I. cAMP-dependent protein kinase types I and II differentially regulate cAMP response element-mediated gene expression. J Biol Chem 2002, 277:18810-18816.
    • (2002) J Biol Chem , vol.277 , pp. 18810-18816
    • Constantinescu, A.1    Gordon, A.S.2    Diamond, I.3
  • 28
    • 0036129469 scopus 로고    scopus 로고
    • Reduced neuronal size and glial cell density in area 9 of the dorsolateral prefrontal cortex in subjects with major depressive disorder
    • Cotter D., Mackay D., Chana G., Beasley C., Landau S., Everall I.P. Reduced neuronal size and glial cell density in area 9 of the dorsolateral prefrontal cortex in subjects with major depressive disorder. Cereb Cortex 2002, 12:386-394.
    • (2002) Cereb Cortex , vol.12 , pp. 386-394
    • Cotter, D.1    Mackay, D.2    Chana, G.3    Beasley, C.4    Landau, S.5    Everall, I.P.6
  • 29
    • 0028088929 scopus 로고
    • Adenylyl cyclase activity and G-protein subunit levels in postmortem frontal cortex of suicide victims
    • Cowburn R.F., Marcusson J.O., Eriksson A., Wiehager B., O'Neill C. Adenylyl cyclase activity and G-protein subunit levels in postmortem frontal cortex of suicide victims. Brain Res 1994, 633:297-304.
    • (1994) Brain Res , vol.633 , pp. 297-304
    • Cowburn, R.F.1    Marcusson, J.O.2    Eriksson, A.3    Wiehager, B.4    O'Neill, C.5
  • 30
    • 35548935578 scopus 로고    scopus 로고
    • Reduced overflow of BDNF from the brain is linked with suicide risk in depressive illness
    • Dawood T., Anderson J., Barton D., Lambert E., Esler M., Hotchkin E. Reduced overflow of BDNF from the brain is linked with suicide risk in depressive illness. Mol Psychiatry 2007, 12:981-983.
    • (2007) Mol Psychiatry , vol.12 , pp. 981-983
    • Dawood, T.1    Anderson, J.2    Barton, D.3    Lambert, E.4    Esler, M.5    Hotchkin, E.6
  • 31
    • 40349086089 scopus 로고    scopus 로고
    • Serum BDNF levels in suicide attempters related to psychosocial stressors: a comparative study with depression
    • Deveci A., Aydemir O., Taskin O., Taneli F., Esen-Danaci A. Serum BDNF levels in suicide attempters related to psychosocial stressors: a comparative study with depression. Neuropsychobiology 2007, 56:93-97.
    • (2007) Neuropsychobiology , vol.56 , pp. 93-97
    • Deveci, A.1    Aydemir, O.2    Taskin, O.3    Taneli, F.4    Esen-Danaci, A.5
  • 32
    • 0032576396 scopus 로고    scopus 로고
    • Increased temporal cortex CREB concentrations and antidepression treatment in major depression
    • Dowlatshahi D., MacQueen G.M., Wang J.F., Young L.T. Increased temporal cortex CREB concentrations and antidepression treatment in major depression. Lancet 1998, 352:1754-1755.
    • (1998) Lancet , vol.352 , pp. 1754-1755
    • Dowlatshahi, D.1    MacQueen, G.M.2    Wang, J.F.3    Young, L.T.4
  • 34
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R.S., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 2006, 59:1116-1127.
    • (2006) Biol Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 36
    • 36349009592 scopus 로고    scopus 로고
    • The concept of dysregulated signal transduction and gene expression in the pathophysiology of mood disorders
    • Dwivedi Y. The concept of dysregulated signal transduction and gene expression in the pathophysiology of mood disorders. Curr Psychiatry Rev 2005, 1:227-254.
    • (2005) Curr Psychiatry Rev , vol.1 , pp. 227-254
    • Dwivedi, Y.1
  • 37
    • 36349009592 scopus 로고    scopus 로고
    • The concept of dysregulated signal transduction and gene expression in the pathophysiology of mood disorders
    • Dwivedi Y. The concept of dysregulated signal transduction and gene expression in the pathophysiology of mood disorders. Curr Psychiatry Rev 2006, 1:227-257.
    • (2006) Curr Psychiatry Rev , vol.1 , pp. 227-257
    • Dwivedi, Y.1
  • 38
    • 77953102584 scopus 로고    scopus 로고
    • BDNF in suicide pathogenesis
    • Dwivedi Y. BDNF in suicide pathogenesis. Ann Med 2010, 42:87-96.
    • (2010) Ann Med , vol.42 , pp. 87-96
    • Dwivedi, Y.1
  • 39
    • 0033942985 scopus 로고    scopus 로고
    • Adrenal glucocorticoids modulate [3H]cyclic AMP binding to protein kinase A (PKA), cyclic AMP-dependent PKA activity, and protein levels of selective regulatory and catalytic subunit isoforms of PKA in rat brain
    • Dwivedi Y., Pandey G.N. Adrenal glucocorticoids modulate [3H]cyclic AMP binding to protein kinase A (PKA), cyclic AMP-dependent PKA activity, and protein levels of selective regulatory and catalytic subunit isoforms of PKA in rat brain. J Pharmacol Exp Ther 2000, 294:103-116.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 103-116
    • Dwivedi, Y.1    Pandey, G.N.2
  • 40
    • 0035020808 scopus 로고    scopus 로고
    • Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects
    • Dwivedi Y., Rizavi H.S., Roberts R.C., Conley R.C., Tamminga C.A., Pandey G.N. Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects. J Neurochem 2001, 77:916-928.
    • (2001) J Neurochem , vol.77 , pp. 916-928
    • Dwivedi, Y.1    Rizavi, H.S.2    Roberts, R.C.3    Conley, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 41
    • 0036356209 scopus 로고    scopus 로고
    • [3H]cAMP binding sites and protein kinase A activity in the prefrontal cortex of suicide victims
    • Dwivedi Y., Conley R.R., Roberts R.C., Tamminga C.A., Pandey G.N. [3H]cAMP binding sites and protein kinase A activity in the prefrontal cortex of suicide victims. Am J Psychiatry 2002, 159:66-73.
    • (2002) Am J Psychiatry , vol.159 , pp. 66-73
    • Dwivedi, Y.1    Conley, R.R.2    Roberts, R.C.3    Tamminga, C.A.4    Pandey, G.N.5
  • 42
    • 0036193404 scopus 로고    scopus 로고
    • Differential effects of haloperidol and clozapine on [(3)H]cAMP binding, protein kinase A (PKA) activity, and mRNA and protein expression of selective regulatory and catalytic subunit isoforms of PKA in rat brain
    • Dwivedi Y., Rizavi H.S., Pandey G.N. Differential effects of haloperidol and clozapine on [(3)H]cAMP binding, protein kinase A (PKA) activity, and mRNA and protein expression of selective regulatory and catalytic subunit isoforms of PKA in rat brain. J Pharmacol Exp Ther 2002, 301:197-209.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 197-209
    • Dwivedi, Y.1    Rizavi, H.S.2    Pandey, G.N.3
  • 43
    • 0037338519 scopus 로고    scopus 로고
    • Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element-binding protein in postmortem brain of suicide subjects
    • Dwivedi Y., Rao J.S., Rizavi H.S., et al. Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element-binding protein in postmortem brain of suicide subjects. Arch Gen Psychiatry 2003, 60:273-282.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 273-282
    • Dwivedi, Y.1    Rao, J.S.2    Rizavi, H.S.3
  • 44
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects
    • Dwivedi Y., Rizavi H.S., Conley R.R., Roberts R.C., Tamminga C.A., Pandey G.N. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 2003, 60:804-815.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 804-815
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Roberts, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 45
    • 9144253896 scopus 로고    scopus 로고
    • Protein kinase A in postmortem brain of depressed suicide victims: altered expression of specific regulatory and catalytic subunits
    • Dwivedi Y., Rizavi H.S., Shukla P.K., Lyons J., Faludi G., Palkovits M., et al. Protein kinase A in postmortem brain of depressed suicide victims: altered expression of specific regulatory and catalytic subunits. Biol Psychiatry 2004, 55:234-243.
    • (2004) Biol Psychiatry , vol.55 , pp. 234-243
    • Dwivedi, Y.1    Rizavi, H.S.2    Shukla, P.K.3    Lyons, J.4    Faludi, G.5    Palkovits, M.6
  • 46
    • 23644440990 scopus 로고    scopus 로고
    • Suicide brain is associated with decreased expression of neurotrophins
    • Dwivedi Y., Mondal A.C., Rizavi H.S., Conley R.R. Suicide brain is associated with decreased expression of neurotrophins. Biol Psychiatry 2005, 58:315-324.
    • (2005) Biol Psychiatry , vol.58 , pp. 315-324
    • Dwivedi, Y.1    Mondal, A.C.2    Rizavi, H.S.3    Conley, R.R.4
  • 47
    • 32844458346 scopus 로고    scopus 로고
    • ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf
    • Dwivedi Y., Rizavi H.S., Conley R.R., Pandey G.N. ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf. Mol Psychiatry 2006, 11:86-98.
    • (2006) Mol Psychiatry , vol.11 , pp. 86-98
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Pandey, G.N.4
  • 48
    • 58349088923 scopus 로고    scopus 로고
    • Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide
    • Dwivedi Y., Rizavi H., Zhang H., Mondal A., Roberts R.C., Conley R.R., et al. Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide. Biol Psychiatry 2009, 65:319-328.
    • (2009) Biol Psychiatry , vol.65 , pp. 319-328
    • Dwivedi, Y.1    Rizavi, H.2    Zhang, H.3    Mondal, A.4    Roberts, R.C.5    Conley, R.R.6
  • 49
    • 0031030327 scopus 로고    scopus 로고
    • Symptoms, subtype, and suicidality in patients with schizophrenia spectrum disorders
    • Fenton W.S., McGlashan T.H., Victor B.J., Blyler C.R. Symptoms, subtype, and suicidality in patients with schizophrenia spectrum disorders. Am J Psychiatry 1997, 154:199-204.
    • (1997) Am J Psychiatry , vol.154 , pp. 199-204
    • Fenton, W.S.1    McGlashan, T.H.2    Victor, B.J.3    Blyler, C.R.4
  • 50
    • 0032848914 scopus 로고    scopus 로고
    • Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action
    • Francis S.H., Corbin J.D. Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action. Crit Rev Clin Lab Sci 1999, 36:275-328.
    • (1999) Crit Rev Clin Lab Sci , vol.36 , pp. 275-328
    • Francis, S.H.1    Corbin, J.D.2
  • 52
    • 0029899904 scopus 로고    scopus 로고
    • The major catalytic subunit isoforms of cAMP-dependent protein kinase have distinct biochemical properties in vitro and in vivo
    • Gamm D.M., Baude E.J., Uhler M.D. The major catalytic subunit isoforms of cAMP-dependent protein kinase have distinct biochemical properties in vitro and in vivo. J Biol Chem 1996, 271:15736-15742.
    • (1996) J Biol Chem , vol.271 , pp. 15736-15742
    • Gamm, D.M.1    Baude, E.J.2    Uhler, M.D.3
  • 53
    • 0036397762 scopus 로고    scopus 로고
    • Stress, synaptic plasticity, and psychopathology
    • Garcia R. Stress, synaptic plasticity, and psychopathology. Rev Neurosci 2002, 13:195-208.
    • (2002) Rev Neurosci , vol.13 , pp. 195-208
    • Garcia, R.1
  • 54
    • 0023062991 scopus 로고
    • G proteins: transducers of receptor-generated signals
    • Gilman A.G. G proteins: transducers of receptor-generated signals. Annu Rev Biochem 1987, 56:615-649.
    • (1987) Annu Rev Biochem , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 55
    • 2942737059 scopus 로고    scopus 로고
    • Patterns of concomitant psychotropic medication use during a 2-year study comparing clozapine and olanzapine for the prevention of suicidal behavior
    • Glick I.D., Zaninelli R., Hsu C., Young F.K., Weiss L., Gunay I., et al. Patterns of concomitant psychotropic medication use during a 2-year study comparing clozapine and olanzapine for the prevention of suicidal behavior. J Clin Psychiatry 2004, 65:679-685.
    • (2004) J Clin Psychiatry , vol.65 , pp. 679-685
    • Glick, I.D.1    Zaninelli, R.2    Hsu, C.3    Young, F.K.4    Weiss, L.5    Gunay, I.6
  • 57
    • 0034602181 scopus 로고    scopus 로고
    • Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap1-extracellular signal-regulated kinase pathway
    • Grewal S.S., Fass D.M., Yao H., Ellig C.L., Goodman R.H., Stork P.J. Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap1-extracellular signal-regulated kinase pathway. J Biol Chem 2000, 275:34433-34441.
    • (2000) J Biol Chem , vol.275 , pp. 34433-34441
    • Grewal, S.S.1    Fass, D.M.2    Yao, H.3    Ellig, C.L.4    Goodman, R.H.5    Stork, P.J.6
  • 58
    • 36349027843 scopus 로고    scopus 로고
    • Is it time to reassess the BDNF hypothesis of depression?
    • Groves J.O. Is it time to reassess the BDNF hypothesis of depression?. Mol Psychiatry 2007, 12:1079-1088.
    • (2007) Mol Psychiatry , vol.12 , pp. 1079-1088
    • Groves, J.O.1
  • 59
    • 17144385440 scopus 로고    scopus 로고
    • Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus
    • Hajsza T., MacLusky N.J., Leranth C. Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus. Eur J Neurosci 2005, 21:1299-1303.
    • (2005) Eur J Neurosci , vol.21 , pp. 1299-1303
    • Hajsza, T.1    MacLusky, N.J.2    Leranth, C.3
  • 60
    • 0031984517 scopus 로고    scopus 로고
    • The many faces of G protein signaling
    • Hamm H.E. The many faces of G protein signaling. J Biol Chem 1998, 273:669-672.
    • (1998) J Biol Chem , vol.273 , pp. 669-672
    • Hamm, H.E.1
  • 61
    • 0025909632 scopus 로고
    • Enhancement of the actions of smg p21 GDP/GTP exchange protein by the protein kinase A-catalyzed phosphorylation of smg p21
    • Hata Y., Kaibuchi K., Kawamura S., Hiroyoshi M., Shirataki H., Takai Y. Enhancement of the actions of smg p21 GDP/GTP exchange protein by the protein kinase A-catalyzed phosphorylation of smg p21. J Biol Chem 1991, 266:6571-6577.
    • (1991) J Biol Chem , vol.266 , pp. 6571-6577
    • Hata, Y.1    Kaibuchi, K.2    Kawamura, S.3    Hiroyoshi, M.4    Shirataki, H.5    Takai, Y.6
  • 62
    • 0142024483 scopus 로고    scopus 로고
    • Rap1 GTPase: functions, regulation, and malignancy
    • Hattori M., Minato N. Rap1 GTPase: functions, regulation, and malignancy. J Biochem 2003, 134:479-484.
    • (2003) J Biochem , vol.134 , pp. 479-484
    • Hattori, M.1    Minato, N.2
  • 63
    • 12144282766 scopus 로고    scopus 로고
    • Suicidal risk during treatment with clozapine: a meta-analysis
    • Hennen J., Baldessarini R.J. Suicidal risk during treatment with clozapine: a meta-analysis. Schizophr Res 2005, 73:139-145.
    • (2005) Schizophr Res , vol.73 , pp. 139-145
    • Hennen, J.1    Baldessarini, R.J.2
  • 64
    • 0030771361 scopus 로고    scopus 로고
    • Role of subunit diversity in signaling by heterotrimeric G proteins
    • Hildebrandt J.D. Role of subunit diversity in signaling by heterotrimeric G proteins. Biochem Pharmacol 1997, 54:325-339.
    • (1997) Biochem Pharmacol , vol.54 , pp. 325-339
    • Hildebrandt, J.D.1
  • 65
    • 0034889602 scopus 로고    scopus 로고
    • Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controls
    • Hiroi N., Wong M.L., Licinio J. Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controls. Mol Psychiatry 2001, 6:540-546.
    • (2001) Mol Psychiatry , vol.6 , pp. 540-546
    • Hiroi, N.1    Wong, M.L.2    Licinio, J.3
  • 66
    • 0033091035 scopus 로고    scopus 로고
    • Assessing the machinery of mind: synapses in neuropsychiatric disorders
    • Honer W.G. Assessing the machinery of mind: synapses in neuropsychiatric disorders. J Psychiatry Neurosci 1999, 24:116-121.
    • (1999) J Psychiatry Neurosci , vol.24 , pp. 116-121
    • Honer, W.G.1
  • 67
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: roles in neuronal development and function
    • Huang E., Reichardt L.F. Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci 2001, 24:677-736.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 677-736
    • Huang, E.1    Reichardt, L.F.2
  • 68
    • 0032191933 scopus 로고    scopus 로고
    • Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation
    • Impey S., Obrietan K., Wong S.T., Poser S., Yano S., Wayman G., et al. Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron 1998, 21:869-883.
    • (1998) Neuron , vol.21 , pp. 869-883
    • Impey, S.1    Obrietan, K.2    Wong, S.T.3    Poser, S.4    Yano, S.5    Wayman, G.6
  • 69
    • 17844386097 scopus 로고    scopus 로고
    • Effects of chronic stress on structure and cell function in rat hippocampus and hypothalamus
    • Joëls M., Karst H., Alfarez D., Heine V.M., Qin Y., van Riel E., et al. Effects of chronic stress on structure and cell function in rat hippocampus and hypothalamus. Stress 2004, 7:221-231.
    • (2004) Stress , vol.7 , pp. 221-231
    • Joëls, M.1    Karst, H.2    Alfarez, D.3    Heine, V.M.4    Qin, Y.5    van Riel, E.6
  • 71
    • 0034644509 scopus 로고    scopus 로고
    • Signaling networks: the origins of cellular multitasking
    • Jordan J.D., Landau E.M., Iyengar R. Signaling networks: the origins of cellular multitasking. Cell 2000, 103:193-200.
    • (2000) Cell , vol.103 , pp. 193-200
    • Jordan, J.D.1    Landau, E.M.2    Iyengar, R.3
  • 72
    • 0031942984 scopus 로고    scopus 로고
    • The effect of clinical outcome on platelet G proteins of major depressed patients
    • Karege F., Bovier P., Stepanian R., Malafosse A. The effect of clinical outcome on platelet G proteins of major depressed patients. Eur Neuropsychopharmacol 1998, 8:89-94.
    • (1998) Eur Neuropsychopharmacol , vol.8 , pp. 89-94
    • Karege, F.1    Bovier, P.2    Stepanian, R.3    Malafosse, A.4
  • 73
    • 0037119177 scopus 로고    scopus 로고
    • Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets
    • Karege F., Schwald M., Cisse M. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 2002, 328:261-264.
    • (2002) Neurosci Lett , vol.328 , pp. 261-264
    • Karege, F.1    Schwald, M.2    Cisse, M.3
  • 74
    • 18944406852 scopus 로고    scopus 로고
    • Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs
    • Karege F., Vaudan G., Schwald M., Perroud N., La Harpe R. Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res Mol Brain Res 2005, 136:29-37.
    • (2005) Brain Res Mol Brain Res , vol.136 , pp. 29-37
    • Karege, F.1    Vaudan, G.2    Schwald, M.3    Perroud, N.4    La Harpe, R.5
  • 75
    • 0024263345 scopus 로고
    • A novel small molecular weight GTP-binding protein with the same putative effector domain as the ras proteins in bovine brain membranes: purification, determination of primary structure, and characterization
    • Kawata M., Matsui Y., Kondo J., Hishida T., Teranishi Y., Takai Y. A novel small molecular weight GTP-binding protein with the same putative effector domain as the ras proteins in bovine brain membranes: purification, determination of primary structure, and characterization. J Biol Chem 1988, 263:18965-18971.
    • (1988) J Biol Chem , vol.263 , pp. 18965-18971
    • Kawata, M.1    Matsui, Y.2    Kondo, J.3    Hishida, T.4    Teranishi, Y.5    Takai, Y.6
  • 76
    • 0342288642 scopus 로고    scopus 로고
    • The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia
    • Keck P.E., Strakowski S.M., McElroy S.L. The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia. J Clin Psychiatry 2000, 61(Suppl 3):4-9.
    • (2000) J Clin Psychiatry , vol.61 , Issue.SUPPL 3 , pp. 4-9
    • Keck, P.E.1    Strakowski, S.M.2    McElroy, S.L.3
  • 77
    • 0036773659 scopus 로고    scopus 로고
    • Neuroleptics and mortality in schizophrenia: prospective analysis of deaths in a French cohort of schizophrenic patients
    • Montout C., Casadebaig F., Lagnaoui R., et al. Neuroleptics and mortality in schizophrenia: prospective analysis of deaths in a French cohort of schizophrenic patients. Schizophr Res 2002, 57:147-156.
    • (2002) Schizophr Res , vol.57 , pp. 147-156
    • Montout, C.1    Casadebaig, F.2    Lagnaoui, R.3
  • 78
    • 0034849763 scopus 로고    scopus 로고
    • Symptom reduction and suicide risk among patients treated with placebo in antipsychotic clinical trials: an analysis of the Food and Drug Administration database
    • Khan A., Khan S.R., Leventhal R.M., Brown W.A. Symptom reduction and suicide risk among patients treated with placebo in antipsychotic clinical trials: an analysis of the Food and Drug Administration database. Am J Psychiatry 2001, 158:1449-1454.
    • (2001) Am J Psychiatry , vol.158 , pp. 1449-1454
    • Khan, A.1    Khan, S.R.2    Leventhal, R.M.3    Brown, W.A.4
  • 80
    • 0034653487 scopus 로고    scopus 로고
    • Neural cell adhesion molecule-stimulated neurite outgrowth depends on activation of protein kinase C and the Ras-mitogen-activated protein kinase pathway
    • Kolkova K., Novitskaya V., Pedersen N., Berzin V., Bock E. Neural cell adhesion molecule-stimulated neurite outgrowth depends on activation of protein kinase C and the Ras-mitogen-activated protein kinase pathway. J Neurosci 2000, 20:2238-2246.
    • (2000) J Neurosci , vol.20 , pp. 2238-2246
    • Kolkova, K.1    Novitskaya, V.2    Pedersen, N.3    Berzin, V.4    Bock, E.5
  • 81
    • 0037351557 scopus 로고    scopus 로고
    • Interactions of cyclic adenosine monophosphate, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor treatment on the survival and growth of postnatal mesencephalic dopamine neurons in vitro
    • Lara J., Kusano K., House S., Gainer H. Interactions of cyclic adenosine monophosphate, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor treatment on the survival and growth of postnatal mesencephalic dopamine neurons in vitro. Exp Neurol 2003, 180:32-45.
    • (2003) Exp Neurol , vol.180 , pp. 32-45
    • Lara, J.1    Kusano, K.2    House, S.3    Gainer, H.4
  • 83
    • 34249933662 scopus 로고    scopus 로고
    • Decreased plasma BDNF level in depressive patients
    • Lee B.H., Kim H., Park S.H., Kim Y.K. Decreased plasma BDNF level in depressive patients. J Affect Disord 2007, 101:239-244.
    • (2007) J Affect Disord , vol.101 , pp. 239-244
    • Lee, B.H.1    Kim, H.2    Park, S.H.3    Kim, Y.K.4
  • 84
    • 0029947711 scopus 로고    scopus 로고
    • Regulation by cAMP-dependent protein kinase of a G-protein-mediated phospholipase C
    • Liu M., Simon M.I. Regulation by cAMP-dependent protein kinase of a G-protein-mediated phospholipase C. Nature 1996, 382:83-87.
    • (1996) Nature , vol.382 , pp. 83-87
    • Liu, M.1    Simon, M.I.2
  • 85
    • 0026452610 scopus 로고
    • Localization and quantification of pro-opiomelanocortin mRNA and glucocorticoid receptor mRNA in pituitaries of suicide victims
    • Lopez J.F., Palkovits M., Arato M., Mansour A., Akil H., Watson S.J. Localization and quantification of pro-opiomelanocortin mRNA and glucocorticoid receptor mRNA in pituitaries of suicide victims. Neuroendocrinology 1992, 56:491-501.
    • (1992) Neuroendocrinology , vol.56 , pp. 491-501
    • Lopez, J.F.1    Palkovits, M.2    Arato, M.3    Mansour, A.4    Akil, H.5    Watson, S.J.6
  • 86
    • 0030610938 scopus 로고    scopus 로고
    • Brain [3H]cAMP binding sites are unaltered in depressed suicides, but decreased by antidepressants
    • Lowther S., Katona C.L., Crompton M.R., Horton R.W. Brain [3H]cAMP binding sites are unaltered in depressed suicides, but decreased by antidepressants. Brain Res 1997, 758:223-228.
    • (1997) Brain Res , vol.758 , pp. 223-228
    • Lowther, S.1    Katona, C.L.2    Crompton, M.R.3    Horton, R.W.4
  • 87
    • 0025301644 scopus 로고
    • Immunocytochemical localization of the neural-specific regulatory subunit of the type II cyclic AMP-dependent protein kinase to postsynaptic structures in the rat brain
    • Ludvig N., Ribak C.E., Scott J.D., Rubin C.S. Immunocytochemical localization of the neural-specific regulatory subunit of the type II cyclic AMP-dependent protein kinase to postsynaptic structures in the rat brain. Brain Res 1990, 520:90-102.
    • (1990) Brain Res , vol.520 , pp. 90-102
    • Ludvig, N.1    Ribak, C.E.2    Scott, J.D.3    Rubin, C.S.4
  • 88
    • 0034142085 scopus 로고    scopus 로고
    • Is CREB a key to neuronal survival?
    • Marshall R., Dragunow M. Is CREB a key to neuronal survival?. Trends Neurosci 2000, 23:48-53.
    • (2000) Trends Neurosci , vol.23 , pp. 48-53
    • Marshall, R.1    Dragunow, M.2
  • 89
    • 0033537710 scopus 로고    scopus 로고
    • Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinase
    • Matsushita M., Nairn A.C. Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinase. J Biol Chem 1999, 274:10086-10093.
    • (1999) J Biol Chem , vol.274 , pp. 10086-10093
    • Matsushita, M.1    Nairn, A.C.2
  • 90
    • 0032912252 scopus 로고    scopus 로고
    • Stress and hippocampal plasticity
    • McEwen B.S. Stress and hippocampal plasticity. Annu Rev Neurosci 1999, 22:105-122.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 105-122
    • McEwen, B.S.1
  • 91
    • 0034667292 scopus 로고    scopus 로고
    • Effects of adverse experiences for brain structure and function
    • McEwen B.S. Effects of adverse experiences for brain structure and function. Biol Psychiatry 2000, 48:713-714.
    • (2000) Biol Psychiatry , vol.48 , pp. 713-714
    • McEwen, B.S.1
  • 92
    • 21344474235 scopus 로고    scopus 로고
    • Decreasing suicide in schizophrenia
    • Meltzer H.Y. Decreasing suicide in schizophrenia. Psychiatr Times 2001, 18:1-5.
    • (2001) Psychiatr Times , vol.18 , pp. 1-5
    • Meltzer, H.Y.1
  • 93
    • 0028869668 scopus 로고
    • Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment
    • Meltzer H.Y., Okayli G. Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment. Am J Psychiatry 1995, 152:183-190.
    • (1995) Am J Psychiatry , vol.152 , pp. 183-190
    • Meltzer, H.Y.1    Okayli, G.2
  • 94
    • 0037227192 scopus 로고    scopus 로고
    • International Suicide Prevention Trial Study Group. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT)
    • Meltzer H.Y., Alphs L., Green A.I., Altamura A.C., Anand R., Bertoldi A., et al. International Suicide Prevention Trial Study Group. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch Gen Psychiatry 2003, 60:82-91.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 82-91
    • Meltzer, H.Y.1    Alphs, L.2    Green, A.I.3    Altamura, A.C.4    Anand, R.5    Bertoldi, A.6
  • 96
    • 0023461701 scopus 로고
    • Epidemiology of suicide
    • Monk M. Epidemiology of suicide. Epidemiol Rev 1987, 9:51-69.
    • (1987) Epidemiol Rev , vol.9 , pp. 51-69
    • Monk, M.1
  • 97
    • 0041346211 scopus 로고    scopus 로고
    • Rap1 couples cAMP signaling to a distinct pool of p42/44 MAPK regulating excitability, synaptic plasticity, learning, and memory
    • Morozov A., Muzzio I.A., Bourtcholadze R., Van-Strien N., Lapidus K., Yin D.Q. Rap1 couples cAMP signaling to a distinct pool of p42/44 MAPK regulating excitability, synaptic plasticity, learning, and memory. Cell 2003, 39:309-325.
    • (2003) Cell , vol.39 , pp. 309-325
    • Morozov, A.1    Muzzio, I.A.2    Bourtcholadze, R.3    Van-Strien, N.4    Lapidus, K.5    Yin, D.Q.6
  • 98
    • 0003454670 scopus 로고
    • Advance report of final mortality statistics
    • National Center for Health Statistics
    • National Center for Health Statistics Advance report of final mortality statistics. NCHS Monthly Vital Stat Rep 1992, 40.
    • (1992) NCHS Monthly Vital Stat Rep , vol.40
  • 99
    • 0028860268 scopus 로고
    • Heterotrimeric G proteins: organizers of transmembrane signals
    • Neer E.J. Heterotrimeric G proteins: organizers of transmembrane signals. Cell 1995, 80:249-257.
    • (1995) Cell , vol.80 , pp. 249-257
    • Neer, E.J.1
  • 100
    • 0003024039 scopus 로고
    • Protein phosphorylation and the regulation of neuronal function
    • Little Brown Press, Boston, MA, G.J. Siegel, R.W. Albers, B.W. Agranoff, P. Molinoff (Eds.)
    • Nestler E.J., Greengard P. Protein phosphorylation and the regulation of neuronal function. Basic Neurochemistry: Molecular, Cellular, and Medical Aspects 1994, 449-474. Little Brown Press, Boston, MA. G.J. Siegel, R.W. Albers, B.W. Agranoff, P. Molinoff (Eds.).
    • (1994) Basic Neurochemistry: Molecular, Cellular, and Medical Aspects , pp. 449-474
    • Nestler, E.J.1    Greengard, P.2
  • 103
    • 0029992189 scopus 로고    scopus 로고
    • Chronic antidepressant administration increases the expression of cAMP response element-binding protein (CREB) in rat hippocampus
    • Nibuya M., Nestler E.J., Duman R.S. Chronic antidepressant administration increases the expression of cAMP response element-binding protein (CREB) in rat hippocampus. J Neurosci 1996, 16:2365-2372.
    • (1996) J Neurosci , vol.16 , pp. 2365-2372
    • Nibuya, M.1    Nestler, E.J.2    Duman, R.S.3
  • 104
    • 0035917794 scopus 로고    scopus 로고
    • Cyclic AMP-mediated signaling components are upregulated in the prefrontal cortex of depressed suicide victims
    • Odagaki Y., Garcia-Sevilla J.A., Huguelet P., La Harpe R., Koyama T., Guimon J. Cyclic AMP-mediated signaling components are upregulated in the prefrontal cortex of depressed suicide victims. Brain Res 2001, 898:224-231.
    • (2001) Brain Res , vol.898 , pp. 224-231
    • Odagaki, Y.1    Garcia-Sevilla, J.A.2    Huguelet, P.3    La Harpe, R.4    Koyama, T.5    Guimon, J.6
  • 105
    • 0027329830 scopus 로고
    • Imbalance of the Gs and Gi/o function in postmortem human brain of depressed patients
    • Ozawa H., Gsell W., Frolich L., et al. Imbalance of the Gs and Gi/o function in postmortem human brain of depressed patients. J Neural Transm Gen Sect 1993, 94:63-69.
    • (1993) J Neural Transm Gen Sect , vol.94 , pp. 63-69
    • Ozawa, H.1    Gsell, W.2    Frolich, L.3
  • 107
    • 33745833987 scopus 로고    scopus 로고
    • Monoamine receptors and signal transduction mechanisms in suicide
    • Pandey G.N., Dwivedi Y. Monoamine receptors and signal transduction mechanisms in suicide. Curr Psychiatry Rev 2006, 2:51-75.
    • (2006) Curr Psychiatry Rev , vol.2 , pp. 51-75
    • Pandey, G.N.1    Dwivedi, Y.2
  • 108
    • 34250176934 scopus 로고    scopus 로고
    • Noradrenergic function in suicide
    • Pandey G.N., Dwivedi Y. Noradrenergic function in suicide. Arch Suicide Res 2007, 11:235-246.
    • (2007) Arch Suicide Res , vol.11 , pp. 235-246
    • Pandey, G.N.1    Dwivedi, Y.2
  • 109
    • 23844458271 scopus 로고    scopus 로고
    • Brain region specific alterations in the protein and mRNA levels of protein kinase A subunits in the postmortem brain of teenage suicide victims
    • Pandey G.N., Dwivedi Y., Ren X., et al. Brain region specific alterations in the protein and mRNA levels of protein kinase A subunits in the postmortem brain of teenage suicide victims. Neuropsychopharmacology 2005, 30:1548-1556.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1548-1556
    • Pandey, G.N.1    Dwivedi, Y.2    Ren, X.3
  • 110
    • 42449119452 scopus 로고    scopus 로고
    • Cyclic AMP response element-binding protein in postmortem brain of teenage suicide victims: specific decrease in the prefrontal cortex but not the hippocampus
    • Pandey G.N., Dwivedi Y., Ren X., Rizavi H.S., Roberts R.C., Conley R.R. Cyclic AMP response element-binding protein in postmortem brain of teenage suicide victims: specific decrease in the prefrontal cortex but not the hippocampus. Int J Neuropsychopharmacol 2006, 18:1-9.
    • (2006) Int J Neuropsychopharmacol , vol.18 , pp. 1-9
    • Pandey, G.N.1    Dwivedi, Y.2    Ren, X.3    Rizavi, H.S.4    Roberts, R.C.5    Conley, R.R.6
  • 111
    • 0033019227 scopus 로고    scopus 로고
    • Abnormalities of cyclic adenosine monophosphate signaling in platelets from untreated patients with bipolar disorder
    • Perez J., Tardito D., Mori S., Racagni G., Smeraldi E., Zanardi R. Abnormalities of cyclic adenosine monophosphate signaling in platelets from untreated patients with bipolar disorder. Arch Gen Psychiatry 1999, 56:248-253.
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 248-253
    • Perez, J.1    Tardito, D.2    Mori, S.3    Racagni, G.4    Smeraldi, E.5    Zanardi, R.6
  • 112
    • 0034162071 scopus 로고    scopus 로고
    • Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder
    • Perez J., Tardito D., Mori S., Racagni G., Smeraldi E., Zanardi R. Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder. J Psychiatr Res 2000, 34:99-104.
    • (2000) J Psychiatr Res , vol.34 , pp. 99-104
    • Perez, J.1    Tardito, D.2    Mori, S.3    Racagni, G.4    Smeraldi, E.5    Zanardi, R.6
  • 113
    • 0035136797 scopus 로고    scopus 로고
    • Protein kinase A and Rap1 levels in platelets of untreated patients with major depression
    • Perez J., Tardito D., Mori S., Racagni G., Smeraldi E., Zanardi R. Protein kinase A and Rap1 levels in platelets of untreated patients with major depression. Mol Psychiatry 2001, 6:44-49.
    • (2001) Mol Psychiatry , vol.6 , pp. 44-49
    • Perez, J.1    Tardito, D.2    Mori, S.3    Racagni, G.4    Smeraldi, E.5    Zanardi, R.6
  • 114
    • 0036183526 scopus 로고    scopus 로고
    • CAMP signaling pathway in depressed patients with psychotic features
    • Perez J., Tardito D., Racagni G., Smeraldi E., Zanardi R. cAMP signaling pathway in depressed patients with psychotic features. Mol Psychiatry 2002, 7:208-212.
    • (2002) Mol Psychiatry , vol.7 , pp. 208-212
    • Perez, J.1    Tardito, D.2    Racagni, G.3    Smeraldi, E.4    Zanardi, R.5
  • 115
    • 0018595618 scopus 로고
    • Reversal of learned helplessness by imipramine
    • Petty F., Sherman A.D. Reversal of learned helplessness by imipramine. Commun Psychopharmacol 1979, 3:371-373.
    • (1979) Commun Psychopharmacol , vol.3 , pp. 371-373
    • Petty, F.1    Sherman, A.D.2
  • 116
    • 0038314475 scopus 로고    scopus 로고
    • Suicide and schizophrenia: a review of literature for the decade (1990-1999) and implications for mental health nursing
    • Pinikahana J., Happell B., Keks N.A. Suicide and schizophrenia: a review of literature for the decade (1990-1999) and implications for mental health nursing. Issues Ment Health Nurs 2003, 24:27-43.
    • (2003) Issues Ment Health Nurs , vol.24 , pp. 27-43
    • Pinikahana, J.1    Happell, B.2    Keks, N.A.3
  • 117
    • 0023801510 scopus 로고
    • Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B)
    • Pizon V., Lerosey I., Chardin P., Tavitian A. Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B). Nucleic Acids Res 1988, 16:7719.
    • (1988) Nucleic Acids Res , vol.16 , pp. 7719
    • Pizon, V.1    Lerosey, I.2    Chardin, P.3    Tavitian, A.4
  • 118
    • 9044233633 scopus 로고    scopus 로고
    • Impaired hippocampal plasticity in mice lacking the Cβ catalytic subunit of cAMP-dependent protein kinase
    • Qi M., Zhuo M., Skalhegg B.S., et al. Impaired hippocampal plasticity in mice lacking the Cβ catalytic subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 1996, 93:1571-1576.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1571-1576
    • Qi, M.1    Zhuo, M.2    Skalhegg, B.S.3
  • 119
    • 0034644733 scopus 로고    scopus 로고
    • Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins
    • Qiu W., Zhuang S., von Lintig F.C., Boss G.R., Pilz R.B. Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins. J Biol Chem 2000, 275:31921-31929.
    • (2000) J Biol Chem , vol.275 , pp. 31921-31929
    • Qiu, W.1    Zhuang, S.2    von Lintig, F.C.3    Boss, G.R.4    Pilz, R.B.5
  • 121
    • 0032869709 scopus 로고    scopus 로고
    • Suicidal behavior in patients with schizophrenia and other psychotic disorders
    • Radomsky E.D., Haas G.L., Mann J.J., Sweeney J.A. Suicidal behavior in patients with schizophrenia and other psychotic disorders. Am J Psychiatry 1999, 156:1590-1595.
    • (1999) Am J Psychiatry , vol.156 , pp. 1590-1595
    • Radomsky, E.D.1    Haas, G.L.2    Mann, J.J.3    Sweeney, J.A.4
  • 122
    • 0031590701 scopus 로고    scopus 로고
    • Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients
    • Rajkowska G. Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients. Ann NY Acad Sci U S A 1997, 836:253-268.
    • (1997) Ann NY Acad Sci U S A , vol.836 , pp. 253-268
    • Rajkowska, G.1
  • 123
    • 0036782251 scopus 로고    scopus 로고
    • Cell pathology in mood disorders
    • Rajkowska G. Cell pathology in mood disorders. Semin Clin Neuropsychiatry 2002, 7:281-292.
    • (2002) Semin Clin Neuropsychiatry , vol.7 , pp. 281-292
    • Rajkowska, G.1
  • 124
    • 0034115267 scopus 로고    scopus 로고
    • Structural abnormalities of subicular dendrites in subjects with schizophrenia and mood disorders: preliminary findings
    • Rosoklija G., Toomayan G., Ellis S.P., Keilp J., Mann J.J., Latov N. Structural abnormalities of subicular dendrites in subjects with schizophrenia and mood disorders: preliminary findings. Arch Gen Psychiatry 2000, 57:349-356.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 349-356
    • Rosoklija, G.1    Toomayan, G.2    Ellis, S.P.3    Keilp, J.4    Mann, J.J.5    Latov, N.6
  • 125
    • 0034938284 scopus 로고    scopus 로고
    • Functional brain circuits in depression and remission
    • Sackeim H.A. Functional brain circuits in depression and remission. Arch Gen Psychiatry 2001, 58:649-650.
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 649-650
    • Sackeim, H.A.1
  • 126
    • 0021186718 scopus 로고
    • Identification of a calmodulin-binding protein that co-purifies with the regulatory subunit of brain protein kinase II
    • Sarkar D., Erlichman J., Rubin C.S. Identification of a calmodulin-binding protein that co-purifies with the regulatory subunit of brain protein kinase II. J Biol Chem 1984, 259:9840-9846.
    • (1984) J Biol Chem , vol.259 , pp. 9840-9846
    • Sarkar, D.1    Erlichman, J.2    Rubin, C.S.3
  • 127
    • 0023388024 scopus 로고
    • The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain
    • Scott J.D., Glaccum M.B., Zoller M.J., Uhler M.D., Helfman D.M., McKnight G.S., et al. The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proc Natl Acad Sci USA 1987, 84:5192-5196.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5192-5196
    • Scott, J.D.1    Glaccum, M.B.2    Zoller, M.J.3    Uhler, M.D.4    Helfman, D.M.5    McKnight, G.S.6
  • 128
    • 0025606328 scopus 로고
    • Type II regulatory subunit dimerization determines the subcellular localization of the cAMP-dependent protein kinase
    • Scott J.D., Stofko R.E., McDonald J.R., Comer J.D., Vitalis E.A., Mangili J.A. Type II regulatory subunit dimerization determines the subcellular localization of the cAMP-dependent protein kinase. J Biol Chem 1990, 265:21561-21566.
    • (1990) J Biol Chem , vol.265 , pp. 21561-21566
    • Scott, J.D.1    Stofko, R.E.2    McDonald, J.R.3    Comer, J.D.4    Vitalis, E.A.5    Mangili, J.A.6
  • 129
    • 0014083436 scopus 로고
    • Failure to escape traumatic shock
    • Seligman M.E., Maier S.F. Failure to escape traumatic shock. J Exp Psychol 1967, 74:1-9.
    • (1967) J Exp Psychol , vol.74 , pp. 1-9
    • Seligman, M.E.1    Maier, S.F.2
  • 130
    • 33750703602 scopus 로고    scopus 로고
    • Crosstalk between cAMP-PKA and MAP kinase pathways is a key regulatory design necessary to regulate FLO11 expression
    • Sengupta N., Vinod P.K., Venkatesh K.V. Crosstalk between cAMP-PKA and MAP kinase pathways is a key regulatory design necessary to regulate FLO11 expression. Biophys Chem 2007, 125:59-71.
    • (2007) Biophys Chem , vol.125 , pp. 59-71
    • Sengupta, N.1    Vinod, P.K.2    Venkatesh, K.V.3
  • 131
    • 0034667293 scopus 로고    scopus 로고
    • 3D MRI studies of neuroanatomic changes in unipolar depression: the role of stress and medical comorbidity
    • Sheline Y.I. 3D MRI studies of neuroanatomic changes in unipolar depression: the role of stress and medical comorbidity. Biol Psychiatry 2000, 48:791-800.
    • (2000) Biol Psychiatry , vol.48 , pp. 791-800
    • Sheline, Y.I.1
  • 132
    • 79958127538 scopus 로고    scopus 로고
    • Protein kinases A and C in post-mortem prefrontal cortex from persons with major depression and normal controls
    • Shelton R.C., Hal Manier D., Lewis D.A. Protein kinases A and C in post-mortem prefrontal cortex from persons with major depression and normal controls. Int J Neuropsychopharmacol 2009, 12:1223-1232.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 1223-1232
    • Shelton, R.C.1    Hal Manier, D.2    Lewis, D.A.3
  • 133
    • 60149086219 scopus 로고    scopus 로고
    • Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A
    • Shelton R.C., Sanders-Bush E., Manier D.H., Lewis D.A. Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A. Neuroscience 2009, 158:1406-1415.
    • (2009) Neuroscience , vol.158 , pp. 1406-1415
    • Shelton, R.C.1    Sanders-Bush, E.2    Manier, D.H.3    Lewis, D.A.4
  • 134
    • 0020039911 scopus 로고
    • Specificity of the learned helplessness model of depression
    • Sherman A.D., Sacquitne J.L., Petty F. Specificity of the learned helplessness model of depression. Pharmacol Biochem Behav 1982, 16:449-454.
    • (1982) Pharmacol Biochem Behav , vol.16 , pp. 449-454
    • Sherman, A.D.1    Sacquitne, J.L.2    Petty, F.3
  • 135
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • Simon M.I., Strathmann M.P., Gautam N. Diversity of G proteins in signal transduction. Science 1991, 252:802-808.
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 136
    • 0034941624 scopus 로고    scopus 로고
    • Suicide and schizophrenia
    • Siris S.G. Suicide and schizophrenia. J Psychopharmacol 2001, 15:127-135.
    • (2001) J Psychopharmacol , vol.15 , pp. 127-135
    • Siris, S.G.1
  • 137
    • 0034241380 scopus 로고    scopus 로고
    • Specificity in the cAMP/PKA signaling pathway: differential expression, regulation, and subcellular localization of subunits of PKA
    • Skalhegg B.S., Tasken K. Specificity in the cAMP/PKA signaling pathway: differential expression, regulation, and subcellular localization of subunits of PKA. Front Biosci 2000, 5:D678-D693.
    • (2000) Front Biosci , vol.5
    • Skalhegg, B.S.1    Tasken, K.2
  • 138
    • 0027521591 scopus 로고
    • The ways in which hormones change cyclic adenosine 3'5'-monophosphate-dependent protein kinase subunits, and how such changes affect cell behavior
    • Spaulding S.W. The ways in which hormones change cyclic adenosine 3'5'-monophosphate-dependent protein kinase subunits, and how such changes affect cell behavior. Endocr Rev 1993, 14:632-650.
    • (1993) Endocr Rev , vol.14 , pp. 632-650
    • Spaulding, S.W.1
  • 140
    • 0027407640 scopus 로고
    • Autoactivation of catalytic (C alpha) subunit of cyclic AMP-dependent protein kinase by phosphorylation of threonine 197
    • Steinberg R.A., Cauthron R.D., Symcox M.M., Shuntoh H. Autoactivation of catalytic (C alpha) subunit of cyclic AMP-dependent protein kinase by phosphorylation of threonine 197. Mol Cell Biol 1993, 13:2332-2341.
    • (1993) Mol Cell Biol , vol.13 , pp. 2332-2341
    • Steinberg, R.A.1    Cauthron, R.D.2    Symcox, M.M.3    Shuntoh, H.4
  • 141
    • 0031590824 scopus 로고    scopus 로고
    • Neurobiology of serotonin in depression and suicide
    • Stockmeier C.A. Neurobiology of serotonin in depression and suicide. Ann NY Acad Sci 1997, 836:220-232.
    • (1997) Ann NY Acad Sci , vol.836 , pp. 220-232
    • Stockmeier, C.A.1
  • 142
    • 2942550646 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in synaptic plasticity and memory
    • Sweatt J.D. Mitogen-activated protein kinases in synaptic plasticity and memory. Curr Opin Neurobiol 2004, 14:311-317.
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 311-317
    • Sweatt, J.D.1
  • 143
    • 0034656653 scopus 로고    scopus 로고
    • High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice
    • Thiele T.E., Willis B., Stadler J., Reynolds J.G., Bernstein I.L., McKnight G.S. High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice. J Neurosci 2000, 20:RC75.
    • (2000) J Neurosci , vol.20
    • Thiele, T.E.1    Willis, B.2    Stadler, J.3    Reynolds, J.G.4    Bernstein, I.L.5    McKnight, G.S.6
  • 144
    • 0028866230 scopus 로고
    • Neurotrophins and neuronal plasticity
    • Thoenen H. Neurotrophins and neuronal plasticity. Science 1995, 270:593-598.
    • (1995) Science , vol.270 , pp. 593-598
    • Thoenen, H.1
  • 145
    • 0023000363 scopus 로고
    • Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase
    • Uhler M.D., Chrivia J.C., McKnight G.S. Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem 1986, 261:15360-15363.
    • (1986) J Biol Chem , vol.261 , pp. 15360-15363
    • Uhler, M.D.1    Chrivia, J.C.2    McKnight, G.S.3
  • 146
    • 0034597723 scopus 로고    scopus 로고
    • Cortisol in violent suicide attempters: association with monoamines and personality
    • Van Heeringen K., Audenaert K., Van de Wiele L., Verstraete A. Cortisol in violent suicide attempters: association with monoamines and personality. J Affect Disord 2000, 60:181-189.
    • (2000) J Affect Disord , vol.60 , pp. 181-189
    • Van Heeringen, K.1    Audenaert, K.2    Van de Wiele, L.3    Verstraete, A.4
  • 147
    • 0031027331 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway
    • Villalba M., Bockaert J., Journot L. Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway. J Neurosci 1997, 17:83-90.
    • (1997) J Neurosci , vol.17 , pp. 83-90
    • Villalba, M.1    Bockaert, J.2    Journot, L.3
  • 148
    • 0030963439 scopus 로고    scopus 로고
    • CAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
    • Vossler M.R., Yao H., York R.D., Pan M.G., Rim C.S., Stork P.J. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 1997, 89:73-82.
    • (1997) Cell , vol.89 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.G.4    Rim, C.S.5    Stork, P.J.6
  • 149
    • 0037243460 scopus 로고    scopus 로고
    • Clozapine: in prevention of suicide in patients with schizophrenia or schizoaffective disorder
    • Wagstaff A., Perry C. Clozapine: in prevention of suicide in patients with schizophrenia or schizoaffective disorder. CNS Drugs 2003, 17:273-280.
    • (2003) CNS Drugs , vol.17 , pp. 273-280
    • Wagstaff, A.1    Perry, C.2
  • 151
    • 0014409394 scopus 로고
    • An adenosine 3',5'-monophosphate-dependant protein kinase from rabbit skeletal muscle
    • Walsh D.A., Perkins J.P., Krebs E.G. An adenosine 3',5'-monophosphate-dependant protein kinase from rabbit skeletal muscle. J Biol Chem 1968, 243:3763-3765.
    • (1968) J Biol Chem , vol.243 , pp. 3763-3765
    • Walsh, D.A.1    Perkins, J.P.2    Krebs, E.G.3
  • 152
    • 0026793294 scopus 로고
    • Protein kinase A inhibits phospholipase C activity and alters protein phosphorylation in rat myometrial plasma membranes
    • Wen Y., Anwer K., Singh S.P., Sanborn B.M. Protein kinase A inhibits phospholipase C activity and alters protein phosphorylation in rat myometrial plasma membranes. Endocrinology 1992, 131:1377-1382.
    • (1992) Endocrinology , vol.131 , pp. 1377-1382
    • Wen, Y.1    Anwer, K.2    Singh, S.P.3    Sanborn, B.M.4
  • 153
    • 0016715190 scopus 로고
    • The Iowa 500: suicide in mania, depression and schizophrenia
    • Winokur G., Tsuang M. The Iowa 500: suicide in mania, depression and schizophrenia. Am J Psychiatry 1975, 132:650-651.
    • (1975) Am J Psychiatry , vol.132 , pp. 650-651
    • Winokur, G.1    Tsuang, M.2
  • 154
    • 0033305003 scopus 로고    scopus 로고
    • Inducible binding of cyclic adenosine 3',5'-monophosphate (cAMP)-responsive element binding protein (CREB) to a cAMP-responsive promoter in vivo
    • Wolf S., Martinez C., Majzoub J.A. Inducible binding of cyclic adenosine 3',5'-monophosphate (cAMP)-responsive element binding protein (CREB) to a cAMP-responsive promoter in vivo. Mol Endocrinol 1999, 13:659-669.
    • (1999) Mol Endocrinol , vol.13 , pp. 659-669
    • Wolf, S.1    Martinez, C.2    Majzoub, J.A.3
  • 155
    • 0037507158 scopus 로고    scopus 로고
    • Reduced phosphorylation of cyclic AMP responsive element-binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder
    • Yamada S., Yamamoto M., Ozawa H., Piederer P., Saito T. Reduced phosphorylation of cyclic AMP responsive element-binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder. J Neural Transm 2003, 110:671-680.
    • (2003) J Neural Transm , vol.110 , pp. 671-680
    • Yamada, S.1    Yamamoto, M.2    Ozawa, H.3    Piederer, P.4    Saito, T.5
  • 156
    • 0035571955 scopus 로고    scopus 로고
    • Postreceptor pathways for signal transduction in depression and bipolar disorder
    • Young L.T. Postreceptor pathways for signal transduction in depression and bipolar disorder. J Psychiatry Neurosci 2001, 26(suppl):S17-S22.
    • (2001) J Psychiatry Neurosci , vol.26 , Issue.SUPPL.
    • Young, L.T.1
  • 157
    • 0027338135 scopus 로고
    • Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder
    • Young L.T., Li P.P., Kish S.J., et al. Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder. J Neurochem 1993, 61:890-898.
    • (1993) J Neurochem , vol.61 , pp. 890-898
    • Young, L.T.1    Li, P.P.2    Kish, S.J.3
  • 158
    • 1542346123 scopus 로고    scopus 로고
    • Amygdala cyclic adenosine monophosphate response element-binding protein phosphorylation in patients with mood disorders: effects of diagnosis, suicide, and drug treatment
    • Young L.T., Bezchlibnyk Y.B., Chen B., Wang J.-F., MacQueen G.M. Amygdala cyclic adenosine monophosphate response element-binding protein phosphorylation in patients with mood disorders: effects of diagnosis, suicide, and drug treatment. Biol Psychiatry 2004, 55:570-577.
    • (2004) Biol Psychiatry , vol.55 , pp. 570-577
    • Young, L.T.1    Bezchlibnyk, Y.B.2    Chen, B.3    Wang, J.-F.4    MacQueen, G.M.5
  • 159
    • 0037045146 scopus 로고    scopus 로고
    • Genetic linkage of region containing the CREB1 gene to depressive disorders in women from families with recurrent, early-onset, major depression
    • Zubenko G.S., Hughes H.B., Maher B.S., Stiffler J.S., Zubenko W.N., Marazita M.L. Genetic linkage of region containing the CREB1 gene to depressive disorders in women from families with recurrent, early-onset, major depression. Am J Med Genet 2002, 114:980-987.
    • (2002) Am J Med Genet , vol.114 , pp. 980-987
    • Zubenko, G.S.1    Hughes, H.B.2    Maher, B.S.3    Stiffler, J.S.4    Zubenko, W.N.5    Marazita, M.L.6
  • 160
    • 0033604512 scopus 로고    scopus 로고
    • Ras and Rap1: two highly related small GTPases with distinct function
    • Zwartkruis F.J.T., Bos J.L. Ras and Rap1: two highly related small GTPases with distinct function. Exp Cell Res 1999, 253:157-165.
    • (1999) Exp Cell Res , vol.253 , pp. 157-165
    • Zwartkruis, F.J.T.1    Bos, J.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.