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Volumn 1, Issue , 2009, Pages 203-213

Signal Transduction in Allergic and Inflammatory Cells

Author keywords

Activation of specific proteins through GTP binding; Epidermal growth factor (EGF) receptors; Immune cells and resident tissue cells participating in allergic diseases; NF B pathway and pathways for cell activation, survival, differentiation; Signal amplification mechanism and signaling through lipid raft; Signal transduction cellular process for environmental cues and cellular response; Signal transduction in allergic and inflammatory cells; Signal transduction in mast cells; Signaling integration and activation of MAPKs

Indexed keywords


EID: 79955977646     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781444300918.ch10     Document Type: Chapter
Times cited : (1)

References (58)
  • 1
    • 0037204953 scopus 로고    scopus 로고
    • A road map for those who don't know JAK-STAT
    • Aaronson, D.S. & Horvath, C.M. (2002) A road map for those who don't know JAK-STAT. Science 296, 1653-5.
    • (2002) Science , vol.296 , pp. 1653-1655
    • Aaronson, D.S.1    Horvath, C.M.2
  • 2
    • 33746769770 scopus 로고    scopus 로고
    • The mechanism of IL-5 signal transduction
    • Adachi, T. & Alam, R. (1998) The mechanism of IL-5 signal transduction. Am J Physiol 275, C623-C633.
    • (1998) Am J Physiol , vol.275
    • Adachi, T.1    Alam, R.2
  • 3
    • 2542478996 scopus 로고    scopus 로고
    • The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
    • Alexander, W.S. & Hilton, D.J. (2004) The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu Rev Immunol 22, 503-29.
    • (2004) Annu Rev Immunol , vol.22 , pp. 503-529
    • Alexander, W.S.1    Hilton, D.J.2
  • 4
    • 33746256913 scopus 로고    scopus 로고
    • You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling
    • Barrow, A.D. & Trowsdale, J. (2006) You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling. Eur J Immunol 36, 1646-53.
    • (2006) Eur J Immunol , vol.36 , pp. 1646-1653
    • Barrow, A.D.1    Trowsdale, J.2
  • 5
    • 7944223078 scopus 로고    scopus 로고
    • Structure and regulation of Src family kinases
    • Boggon, T.J. & Eck, M.J. (2004) Structure and regulation of Src family kinases. Oncogene 23, 7918-27.
    • (2004) Oncogene , vol.23 , pp. 7918-7927
    • Boggon, T.J.1    Eck, M.J.2
  • 6
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L.C. (2002) The phosphoinositide 3-kinase pathway. Science 296, 1655-7.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 7
    • 0037424246 scopus 로고    scopus 로고
    • Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
    • Cen, O., Gorska, M.M., Stafford, S.J., Sur, S. & Alam, R. (2003) Identification of UNC119 as a novel activator of SRC-type tyrosine kinases. J Biol Chem 278, 8837-45.
    • (2003) J Biol Chem , vol.278 , pp. 8837-8845
    • Cen, O.1    Gorska, M.M.2    Stafford, S.J.3    Sur, S.4    Alam, R.5
  • 8
    • 0028340167 scopus 로고
    • ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency
    • Chan, A.C., Kadlecek, T.A., Elder, M.E. et al. (1994) ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 264, 1599-601.
    • (1994) Science , vol.264 , pp. 1599-1601
    • Chan, A.C.1    Kadlecek, T.A.2    Elder, M.E.3
  • 9
    • 16644370412 scopus 로고    scopus 로고
    • Human RAS superfamily proteins and related GTPases
    • Colicelli, J. (2004) Human RAS superfamily proteins and related GTPases. Sci STKE 2004(250), RE13.
    • (2004) Sci STKE , vol.2004 , Issue.250
    • Colicelli, J.1
  • 10
    • 0035898442 scopus 로고    scopus 로고
    • Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice
    • Daheshia, M., Friend, D.S., Grusby, M.J., Austen, K.F. & Katz, H.R. (2001) Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice. J Exp Med 194, 227-33.
    • (2001) J Exp Med , vol.194 , pp. 227-233
    • Daheshia, M.1    Friend, D.S.2    Grusby, M.J.3    Austen, K.F.4    Katz, H.R.5
  • 11
    • 33744830286 scopus 로고    scopus 로고
    • Targeting mitrogen-activated protein kinases for asthma
    • Duan, W. & Wong, W.S. (2006) Targeting mitrogen-activated protein kinases for asthma. Curr Drug Targets 7, 691-8.
    • (2006) Curr Drug Targets , vol.7 , pp. 691-698
    • Duan, W.1    Wong, W.S.2
  • 12
    • 0035854542 scopus 로고    scopus 로고
    • Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation
    • Dupuis, S., Dargemont, C., Fieschi, C. et al. (2001) Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation. Science 293, 300-3.
    • (2001) Science , vol.293 , pp. 300-303
    • Dupuis, S.1    Dargemont, C.2    Fieschi, C.3
  • 13
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S. & Hall, A. (2002) Rho GTPases in cell biology. Nature 420, 629-35.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 14
    • 0029242481 scopus 로고
    • The tyrosine activation motif as a target of protein tyrosine kinases and SH2 domains
    • Flaswinkel, H., Barner, M. & Reth, M. (1995) The tyrosine activation motif as a target of protein tyrosine kinases and SH2 domains. Semin Immunol 7, 21-7.
    • (1995) Semin Immunol , vol.7 , pp. 21-27
    • Flaswinkel, H.1    Barner, M.2    Reth, M.3
  • 15
    • 33344470236 scopus 로고    scopus 로고
    • Integrated signalling pathways for mast-cell activation
    • Gilfillan, A.M. & Tkaczyk, C. (2006) Integrated signalling pathways for mast-cell activation. Nat Rev Immunol 6, 218-30.
    • (2006) Nat Rev Immunol , vol.6 , pp. 218-230
    • Gilfillan, A.M.1    Tkaczyk, C.2
  • 16
    • 0032527136 scopus 로고    scopus 로고
    • Defective expression of p56lck in an infant with severe combined immunodeficiency
    • Goldman, F.D., Ballas, Z.K., Schutte, B.C. et al. (1998) Defective expression of p56lck in an infant with severe combined immunodeficiency. J Clin Invest 102, 421-9.
    • (1998) J Clin Invest , vol.102 , pp. 421-429
    • Goldman, F.D.1    Ballas, Z.K.2    Schutte, B.C.3
  • 17
    • 1342321661 scopus 로고    scopus 로고
    • Unc119, a novel activator of Lck/Fyn, is essential for T cell activation
    • Gorska, M.M., Stafford, S.J., Cen, O., Sur, S. & Alam, R. (2004) Unc119, a novel activator of Lck/Fyn, is essential for T cell activation. J Exp Med 199, 369-79.
    • (2004) J Exp Med , vol.199 , pp. 369-379
    • Gorska, M.M.1    Stafford, S.J.2    Cen, O.3    Sur, S.4    Alam, R.5
  • 18
    • 27444440633 scopus 로고    scopus 로고
    • Cell signalling diversity of the Gqalpha family of heterotrimeric G proteins
    • Hubbard, K.B. & Hepler, J.R. (2006) Cell signalling diversity of the Gqalpha family of heterotrimeric G proteins. Cell Signal 18, 135-50.
    • (2006) Cell Signal , vol.18 , pp. 135-150
    • Hubbard, K.B.1    Hepler, J.R.2
  • 19
    • 0038239874 scopus 로고    scopus 로고
    • Regulation of cytokine receptor signaling by SOCS1
    • Ilangumaran, S. & Rottapel, R. (2003) Regulation of cytokine receptor signaling by SOCS1. Immunol Rev 192, 196-211.
    • (2003) Immunol Rev , vol.192 , pp. 196-211
    • Ilangumaran, S.1    Rottapel, R.2
  • 20
    • 19944433253 scopus 로고    scopus 로고
    • Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness
    • Inoue, H., Kato, R., Fukuyama, S. et al. (2005) Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness. J Exp Med 201, 73-82.
    • (2005) J Exp Med , vol.201 , pp. 73-82
    • Inoue, H.1    Kato, R.2    Fukuyama, S.3
  • 21
    • 0030891713 scopus 로고    scopus 로고
    • ITIMs and ITAMs. The Yin and Yang of antigen and Fc receptor-linked signaling machinery
    • Isakov, N. (1997) ITIMs and ITAMs. The Yin and Yang of antigen and Fc receptor-linked signaling machinery. Immunol Res 16, 85-100.
    • (1997) Immunol Res , vol.16 , pp. 85-100
    • Isakov, N.1
  • 22
    • 27744520682 scopus 로고    scopus 로고
    • Rab proteins, connecting transport and vesicle fusion
    • Jordens, I., Marsman, M., Kuijl, C. & Neefjes, J. (2005) Rab proteins, connecting transport and vesicle fusion. Traffic 6, 1070-7.
    • (2005) Traffic , vol.6 , pp. 1070-1077
    • Jordens, I.1    Marsman, M.2    Kuijl, C.3    Neefjes, J.4
  • 23
    • 0034651636 scopus 로고    scopus 로고
    • Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue
    • Kagami, S., Nakajima, H., Kumano, K. et al. (2000) Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue. Blood 95, 1370-7.
    • (2000) Blood , vol.95 , pp. 1370-1377
    • Kagami, S.1    Nakajima, H.2    Kumano, K.3
  • 24
    • 0034653460 scopus 로고    scopus 로고
    • Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases
    • Kampen, G.T., Stafford, S, Adachi, T. et al. (2000) Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases. Blood 95, 1911-17.
    • (2000) Blood , vol.95 , pp. 1911-1917
    • Kampen, G.T.1    Stafford, S.2    Adachi, T.3
  • 25
    • 0037138370 scopus 로고    scopus 로고
    • Signaling through the JAK/STAT pathway, recent advances and future challenges
    • Kisseleva, T., Bhattacharya, S., Braunstein, J. & Schindler, C.W. (2002) Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285, 1-24.
    • (2002) Gene , vol.285 , pp. 1-24
    • Kisseleva, T.1    Bhattacharya, S.2    Braunstein, J.3    Schindler, C.W.4
  • 26
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li, Q. & Verma, I.M. (2002) NF-kappaB regulation in the immune system. Nat Rev Immunol 2, 725-34.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 27
    • 0037306143 scopus 로고    scopus 로고
    • Transmembrane adapters: attractants for cytoplasmic effectors
    • Lindquist, J.A., Simeoni, L. & Schraven, B. (2003) Transmembrane adapters: attractants for cytoplasmic effectors. Immunol Rev 191, 165-82.
    • (2003) Immunol Rev , vol.191 , pp. 165-182
    • Lindquist, J.A.1    Simeoni, L.2    Schraven, B.3
  • 28
    • 0029164841 scopus 로고
    • Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)
    • Macchi, P., Villa, A., Giliani, S. et al. (1995) Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID). Nature 377, 65-8.
    • (1995) Nature , vol.377 , pp. 65-68
    • Macchi, P.1    Villa, A.2    Giliani, S.3
  • 29
    • 0035542919 scopus 로고    scopus 로고
    • Proteasomal regulation of betac signaling reveals a novel mechanism for cytokine receptor heterotypic desensitization
    • Martinez-Moczygemba, M. & Huston, D.P. (2001) Proteasomal regulation of betac signaling reveals a novel mechanism for cytokine receptor heterotypic desensitization. J Clin Invest 108, 1797-806.
    • (2001) J Clin Invest , vol.108 , pp. 1797-1806
    • Martinez-Moczygemba, M.1    Huston, D.P.2
  • 30
    • 0030956715 scopus 로고    scopus 로고
    • CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation
    • Matsumoto, A., Masuhara, M., Mitsui, K. et al. (1997) CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood 89, 3148-54.
    • (1997) Blood , vol.89 , pp. 3148-3154
    • Matsumoto, A.1    Masuhara, M.2    Mitsui, K.3
  • 31
    • 0033521148 scopus 로고    scopus 로고
    • An essential role for BLNK in human B cell development
    • Minegishi, Y., Rohrer, J., Coustan-Smith, E. et al. (1999) An essential role for BLNK in human B cell development. Science 286, 1954-7.
    • (1999) Science , vol.286 , pp. 1954-1957
    • Minegishi, Y.1    Rohrer, J.2    Coustan-Smith, E.3
  • 32
    • 33845897463 scopus 로고    scopus 로고
    • Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
    • Minegishi, Y., Saito, M., Morio, T. et al. (2006) Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 25, 745-55.
    • (2006) Immunity , vol.25 , pp. 745-755
    • Minegishi, Y.1    Saito, M.2    Morio, T.3
  • 33
    • 0035965317 scopus 로고    scopus 로고
    • Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients
    • Morra, M., Simarro-Grande, M., Martin, M. et al. (2001) Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients. J Biol Chem 276, 36809-16.
    • (2001) J Biol Chem , vol.276 , pp. 36809-36816
    • Morra, M.1    Simarro-Grande, M.2    Martin, M.3
  • 34
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy, K.M. & Reiner, S.L. (2002) The lineage decisions of helper T cells. Nat Rev Immunol 2, 933-44.
    • (2002) Nat Rev Immunol , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 35
    • 0033753014 scopus 로고    scopus 로고
    • Signal transduction by the high-affinity immunoglobulin E receptor Fc epsilon RI: coupling form to function
    • Nadler, M.J., Matthews, S.A., Turner, H. & Kinet, J.P. (2000) Signal transduction by the high-affinity immunoglobulin E receptor Fc epsilon RI: coupling form to function. Adv Immunol 76, 325-55.
    • (2000) Adv Immunol , vol.76 , pp. 325-355
    • Nadler, M.J.1    Matthews, S.A.2    Turner, H.3    Kinet, J.P.4
  • 36
    • 2442668054 scopus 로고    scopus 로고
    • Development and function of T helper 1 cells
    • O'Garra, A. & Robinson, D. (2004) Development and function of T helper 1 cells. Adv Immunol 83, 133-62.
    • (2004) Adv Immunol , vol.83 , pp. 133-162
    • O'Garra, A.1    Robinson, D.2
  • 37
    • 0029835940 scopus 로고    scopus 로고
    • Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB
    • Ono, M., Bolland, S., Tempst, P. & Ravetch, J.V. (1996) Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB. Nature 383, 263-6.
    • (1996) Nature , vol.383 , pp. 263-266
    • Ono, M.1    Bolland, S.2    Tempst, P.3    Ravetch, J.V.4
  • 38
    • 0025845950 scopus 로고
    • Possible interactions between the Fcε receptor and a novel mast cell function-associated antigen
    • Ortega, E., Schneider, H. & Pecht, I. (1991) Possible interactions between the Fcε receptor and a novel mast cell function-associated antigen. Int Immunol 3, 333-42.
    • (1991) Int Immunol , vol.3 , pp. 333-342
    • Ortega, E.1    Schneider, H.2    Pecht, I.3
  • 39
    • 7944231534 scopus 로고    scopus 로고
    • Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation
    • Palacios, E.H. & Weiss, A. (2004) Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene 23, 7990-8000.
    • (2004) Oncogene , vol.23 , pp. 7990-8000
    • Palacios, E.H.1    Weiss, A.2
  • 40
    • 0037115764 scopus 로고    scopus 로고
    • Role of the protein tyrosine phosphatase SHP-1 (Src homology phosphatase-1) in the regulation of interleukin-3-induced survival, proliferation and signalling
    • Paling, N.R. & Welham, M.J. (2002) Role of the protein tyrosine phosphatase SHP-1 (Src homology phosphatase-1) in the regulation of interleukin-3-induced survival, proliferation and signalling. Biochem J 368, 885-94.
    • (2002) Biochem J , vol.368 , pp. 885-894
    • Paling, N.R.1    Welham, M.J.2
  • 41
    • 0028956998 scopus 로고
    • The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway
    • Pazdrak, K., Schreiber, D., Forsythe, P., Justement, L. & Alam, R. (1995) The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway. J Exp Med 181, 1827-34.
    • (1995) J Exp Med , vol.181 , pp. 1827-1834
    • Pazdrak, K.1    Schreiber, D.2    Forsythe, P.3    Justement, L.4    Alam, R.5
  • 42
    • 0037471003 scopus 로고    scopus 로고
    • Pyogenic bacterial infections in humans with IRAK-4 deficiency
    • Picard, C., Puel, A., Bonnet, M. et al. (2003) Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 299, 2076-9.
    • (2003) Science , vol.299 , pp. 2076-2079
    • Picard, C.1    Puel, A.2    Bonnet, M.3
  • 44
    • 0034700364 scopus 로고    scopus 로고
    • Molecular aspects of the cellular activities of ADP-ribosylation factors
    • Randazzo, P.A., Nie, Z., Miura, K. & Hsu, V.W. (2000) Molecular aspects of the cellular activities of ADP-ribosylation factors. Sci STKE 2000(59), RE1.
    • (2000) Sci STKE , vol.2000 , Issue.59
    • Randazzo, P.A.1    Nie, Z.2    Miura, K.3    Hsu, V.W.4
  • 45
    • 0027305921 scopus 로고
    • Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice
    • Rawlings, D.J., Saffran, D.C., Tsukada, S. et al. (1993) Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science 261, 358-61.
    • (1993) Science , vol.261 , pp. 358-361
    • Rawlings, D.J.1    Saffran, D.C.2    Tsukada, S.3
  • 46
    • 14644403593 scopus 로고    scopus 로고
    • NTAL/LAB and LAT: a balancing act in mast-cell activation and function
    • Rivera, J. (2005) NTAL/LAB and LAT: a balancing act in mast-cell activation and function. Trends Immunol 26, 119-22.
    • (2005) Trends Immunol , vol.26 , pp. 119-122
    • Rivera, J.1
  • 47
    • 12744262695 scopus 로고    scopus 로고
    • Merging complexes: properties of membrane raft assembly during lymphocyte signaling
    • Rodgers, W., Farris, D. & Mishra, S. (2005) Merging complexes: properties of membrane raft assembly during lymphocyte signaling. Trends Immunol 26, 97-103.
    • (2005) Trends Immunol , vol.26 , pp. 97-103
    • Rodgers, W.1    Farris, D.2    Mishra, S.3
  • 49
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
    • Roux, P.P. & Blenis, J. (2004) ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 68, 320-44.
    • (2004) Microbiol Mol Biol Rev , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 50
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • Shaw, R.J. & Cantley, L.C. (2006) Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441, 424-30.
    • (2006) Nature , vol.441 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 51
    • 0035340798 scopus 로고    scopus 로고
    • CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A
    • Shlapatska, L.M., Mikhalap, S.V., Berdova, A.G. et al. (2001) CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A. J Immunol 166, 5480-7.
    • (2001) J Immunol , vol.166 , pp. 5480-5487
    • Shlapatska, L.M.1    Mikhalap, S.V.2    Berdova, A.G.3
  • 52
    • 0026623013 scopus 로고
    • Interleukin-3 regulates the activity of the LYN protein-tyrosine kinase in myeloidcommitted leukemic cell lines
    • Torigoe, T., O'Connor, R., Santoli, D. & Reed, J.C. (1992) Interleukin-3 regulates the activity of the LYN protein-tyrosine kinase in myeloidcommitted leukemic cell lines. Blood 80, 617-24.
    • (1992) Blood , vol.80 , pp. 617-624
    • Torigoe, T.1    O'Connor, R.2    Santoli, D.3    Reed, J.C.4
  • 53
    • 0034795143 scopus 로고    scopus 로고
    • Inhibition of IgEmediated mast cell activation by the paired Ig-like receptor PIR-B
    • Uehara, T., Blery, M., Kang, D.W. et al. (2001) Inhibition of IgEmediated mast cell activation by the paired Ig-like receptor PIR-B. J Clin Invest 108, 1041-50.
    • (2001) J Clin Invest , vol.108 , pp. 1041-1050
    • Uehara, T.1    Blery, M.2    Kang, D.W.3
  • 54
    • 0028953733 scopus 로고
    • Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha
    • van der Bruggen, T., Caldenhoven, E., Kanters, D. et al. (1995) Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha. Blood 85, 1442-8.
    • (1995) Blood , vol.85 , pp. 1442-1448
    • Van Der Bruggen, T.1    Caldenhoven, E.2    Kanters, D.3
  • 55
    • 0035474470 scopus 로고    scopus 로고
    • The transmembrane adapter LAT plays a central role in immune receptor signaling
    • Wonerow, P. & Watson, S.P. (2001) The transmembrane adapter LAT plays a central role in immune receptor signaling. Oncogene 20, 297-305.
    • (2001) Oncogene , vol.20 , pp. 297-305
    • Wonerow, P.1    Watson, S.P.2
  • 56
    • 14844361808 scopus 로고    scopus 로고
    • Multisite protein modification and intramolecular signaling
    • Yang, X.J. (2005) Multisite protein modification and intramolecular signaling. Oncogene 24, 1653-62.
    • (2005) Oncogene , vol.24 , pp. 1653-1662
    • Yang, X.J.1
  • 57
    • 33745002702 scopus 로고    scopus 로고
    • An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
    • Zhang, X., Gureasko, J., Shen, K., Cole, P.A. & Kuriyan, J. (2006) An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell 125, 1137-49.
    • (2006) Cell , vol.125 , pp. 1137-1149
    • Zhang, X.1    Gureasko, J.2    Shen, K.3    Cole, P.A.4    Kuriyan, J.5
  • 58
    • 0033658369 scopus 로고    scopus 로고
    • A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO)
    • Zonana, J., Elder, M.E., Schneider, L.C. et al. (2000) A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO). Am J Hum Genet 67, 1555-62.
    • (2000) Am J Hum Genet , vol.67 , pp. 1555-1562
    • Zonana, J.1    Elder, M.E.2    Schneider, L.C.3


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