NTAL/LAB and LAT: A balancing act in mast-cell activation and function

Trends in Immunology

Volumn 26, Issue 3, 2005, Pages 119-122

  Rivera, Juan ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPID; MEMBRANE PROTEIN;

B LYMPHOCYTE ACTIVATION; BINDING SITE; CELL FUNCTION; HUMAN; LIPID RAFT; MAST CELL; NONHUMAN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 14644403593     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2005.01.001     Document Type: Short Survey

References (21)

1. L.E. Samelson Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins Annu. Rev. Immunol. 20 2002 371 394
2. J.A. Lindquist Transmembrane adapters: attractants for cytoplasmic effectors Immunol. Rev. 191 2003 165 182
3. J. Rivera Molecular adapters in FcεRI signaling and the allergic response Curr. Opin. Immunol. 14 2002 688 693
4. S. Saitoh LAT is essential for FcεRI-mediated mast cell activation Immunity 12 2000 525 535
5. S. Saitoh The four distal tyrosines are required for LAT-dependent signaling in FcεRI-mediated mast cell activation J. Exp. Med. 198 2003 831 843
6. T. Brdicka Non-T cell activation linker (NTAL): A transmembrane adaptor protein involved in immunoreceptor signaling J. Exp. Med. 196 2002 1617 1626
7. E. Janssen Linker for activation of B cells: a functional equivalent of a mutant linker for activation of T cells deficient in phospholipase C-γ1 binding J. Immunol. 172 2004 6810 6819
8. S. Koonpaew The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB J. Biol. Chem. 279 2004 11229 11235
9. P. Volna Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL J. Exp. Med. 200 2004 1001 1013
10. M. Zhu Positive and negative regulation of FcεRI-mediated signaling by the adaptor protein LAB/NTAL J. Exp. Med. 200 2004 991 1000
11. S. Odom Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase J. Exp. Med. 199 2004 1491 1502
12. M. Huber The Src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation Proc. Natl. Acad. Sci. U. S. A. 95 1998 11330 11335
13. C. Tkaczyk NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following KIT activation and FcεRI aggregation Blood 104 2004 207 214
14. H. Gu Essential role for Gab2 in the allergic response Nature 412 2001 186 190
15. U. Blank The ins and outs of IgE-dependent mast cell exocytosis Trends Immunol. 25 2004 266 273
16. 2+-regulating signal circuit in B lymphocytes Immunity 21 2004 681 691
17. O. Malbec Linker for activation of T cells integrates positive and negative signaling in mast cells J. Immunol. 173 2004 5086 5094
18. V. Horejsi The roles of membrane microdomains (rafts) in T cell activation Immunol. Rev. 191 2003 148 164
19. B.S. Wilson Observing FcεRI signaling from inside of the mast cell membrane J. Cell Biol. 149 2000 1131 1142
20. B.S. Wilson High resolution mapping of mast cell membranes reveals primary and secondary domains of FcεRI and LAT J. Cell Biol. 154 2001 645 658
21. V. Parravicini Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation Nat. Immunol. 3 2002 741 748