-
1
-
-
0028270016
-
-
Blood 83:1791-1798,1994.
-
Ahlers, A., K. Engel, C. Sott, M. Gaestel, F. Herrmann, and M. A. Brach. Interleukin-3 and granulocyte-macrophage colonystimulating factor induce activation of the MAPKAP kinase 2 resulting in in vitro serine phosphorylation of the small heat shock protein (Hsp 27). Blood 83:1791-1798,1994.
-
K. Engel, C. Sott, M. Gaestel, F. Herrmann, and M. A. Brach. Interleukin-3 and Granulocyte-macrophage Colonystimulating Factor Induce Activation of the MAPKAP Kinase 2 Resulting in in Vitro Serine Phosphorylation of the Small Heat Shock Protein (Hsp 27).
-
-
Ahlers, A.1
-
4
-
-
0028984841
-
-
J. Exp. Med. 182:811-820,1995.
-
Appleby, M. W., J. D. kerner, S. Chien, C. R. Maliszewski, S. Bondada, and R. M. Perlmutter. Involvement of p59fynT in IL-5 receptor signaling. J. Exp. Med. 182:811-820,1995.
-
J. D. Kerner, S. Chien, C. R. Maliszewski, S. Bondada, and R. M. Perlmutter. Involvement of P59fynT in IL-5 Receptor Signaling.
-
-
Appleby, M.W.1
-
5
-
-
0028916417
-
-
EMBOJ. 14:1402-1411,1995.
-
Azam, M., H. Erdjument-Bromage, B. L. Kreider, M. Xia, F. W. Quelle, R. Basu, C. Saris, P. Tempst, J. N. Ihle, and C. Schindler. Interleukin-3 signals through multiple isoibrms of StatS. EMBOJ. 14:1402-1411,1995.
-
H. Erdjument-Bromage, B. L. Kreider, M. Xia, F. W. Quelle, R. Basu, C. Saris, P. Tempst, J. N. Ihle, and C. Schindler. Interleukin-3 Signals through Multiple Isoibrms of StatS.
-
-
Azam, M.1
-
11
-
-
0030056861
-
-
J. Biol. Chem. 271:3562-3567,1996.
-
Brizzi, M. F., M. G. Aronica, A. Rosso, G. P. Bagnara, Y., Yarden, and L. Pegoraro. Granulocyte-macrophage colonystimulating factor stimulates Jak2 signaling pathway and rapidly activates p93fes, STAT1 p91, and STATS p92 in polymorphonuclear leukocytes. J. Biol. Chem. 271:3562-3567,1996.
-
M. G. Aronica, A. Rosso, G. P. Bagnara, Y., Yarden, and L. Pegoraro. Granulocyte-macrophage Colonystimulating Factor Stimulates Jak2 Signaling Pathway and Rapidly Activates P93fes, STAT1 P91, and STATS P92 in Polymorphonuclear Leukocytes.
-
-
Brizzi, M.F.1
-
13
-
-
85177146843
-
-
J. Biol. Chem. 270:25778-25784,1995.
-
Caldenhoven, E., T. van Dijk, J. A. Raaijmakers, J. W. Lammers, L. Koenderman, and R. P. de Groot. Activation of the STATS/acute phase response factor transcription factor by interleukin-5. J. Biol. Chem. 270:25778-25784,1995.
-
T. Van Dijk, J. A. Raaijmakers, J. W. Lammers, L. Koenderman, and R. P. De Groot. Activation of the STATS/acute Phase Response Factor Transcription Factor by Interleukin-5.
-
-
Caldenhoven, E.1
-
15
-
-
0024591512
-
-
Blood 73: 1504-1512, 1989.
-
Clutterbuck, E. J., E. M. Hirst, and C. J. Sanderson. Human interIeukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GM-CSF. Blood 73: 1504-1512, 1989.
-
E. M. Hirst, and C. J. Sanderson. Human InterIeukin-5 (IL-5) Regulates the Production of Eosinophils in Human Bone Marrow Cultures: Comparison and Interaction with IL-1, IL-3, IL-6, and GM-CSF.
-
-
Clutterbuck, E.J.1
-
16
-
-
0032055541
-
-
Blood 91:2547-2557,1998.
-
Coffer, P. J., R. C. Schweizer, G. R. Dubois, T. Maikoe, J. J. Lammers, and L. Koenderman. Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper-2-derived cytokines interleukin-4 and interleukin-5. Blood 91:2547-2557,1998.
-
R. C. Schweizer, G. R. Dubois, T. Maikoe, J. J. Lammers, and L. Koenderman. Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-helper-2-derived Cytokines Interleukin-4 and Interleukin-5.
-
-
Coffer, P.J.1
-
17
-
-
0027201616
-
-
EMBOJ. 12: 2681-2690,1993.
-
Corey, S., A. Eguinoa, K. Puyana-Theall, J. B. Boten, L. Cantley, F. Mollinedo, T. R. Jackson, P. T. Hawkins, and L. R. Stephens. Granulocyte-macrophage colony-stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src-related tyrosine kinase(s) in human myeloid derived cells. EMBOJ. 12: 2681-2690,1993.
-
A. Eguinoa, K. Puyana-Theall, J. B. Boten, L. Cantley, F. Mollinedo, T. R. Jackson, P. T. Hawkins, and L. R. Stephens. Granulocyte-macrophage Colony-stimulating Factor Stimulates both Association and Activation of Phosphoinositide 3OH-kinase and Src-related Tyrosine Kinase(s) in Human Myeloid Derived Cells.
-
-
Corey, S.1
-
19
-
-
0029978202
-
-
Proc. Natl. Acad. Sei. USA 93: 16891693,1996.
-
Damen, J. E., L. Liu, P. Rosten, R. K. Humphries, A. B. Jefferson, P. W. Majerus, and G. Krystal. The 145-kD protein induced to associate with She multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. Proc. Natl. Acad. Sei. USA 93: 16891693,1996.
-
L. Liu, P. Rosten, R. K. Humphries, A. B. Jefferson, P. W. Majerus, and G. Krystal. the 145-kD Protein Induced to Associate with She Multiple Cytokines Is an Inositol Tetraphosphate and Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.
-
-
Damen, J.E.1
-
20
-
-
0029133702
-
-
Science 269: 1721-1723, 1995.
-
David, M., E. Petricoin, C. Benjamin, R. Pine, M. J. Weber, and A. C. Larner. Requirement for MAP kinase (ERK2) activity in Interferon a- and Interferon β-stimulated gene expression through STAT proteins. Science 269: 1721-1723, 1995.
-
E. Petricoin, C. Benjamin, R. Pine, M. J. Weber, and A. C. Larner. Requirement for MAP Kinase (ERK2) Activity in Interferon A- and Interferon β-Stimulated Gene Expression through STAT Proteins.
-
-
David, M.1
-
21
-
-
0031025335
-
-
J. Biol. Chem. 272:2319-2325,1997.
-
De Groot, R. P., T. B. van Dijk, E. Caldenhoven, P. J. Coffer, J. A. Raaijmakers, J. W. J. Lammers, and L. Koenderman. Activation of 12-O-tetradecanoylphorbol-13acetate response element- and dyad symmetry elementdependent transcription by interleukin-5 is mediated by Jun N-terminal kinase/stress-activated protein kinase. J. Biol. Chem. 272:2319-2325,1997.
-
T. B. Van Dijk, E. Caldenhoven, P. J. Coffer, J. A. Raaijmakers, J. W. J. Lammers, and L. Koenderman. Activation of 12-O-tetradecanoylphorbol-13acetate Response Element- and Dyad Symmetry Elementdependent Transcription by Interleukin-5 Is Mediated by Jun N-terminal Kinase/stress-activated Protein Kinase.
-
-
De Groot, R.P.1
-
22
-
-
1842333237
-
-
Science 278:687-689,1997.
-
Del Peso, L., M. Gonzalez-Garcia, C. Page, R. Herrera, and G. Nunez. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687-689,1997.
-
M. Gonzalez-Garcia, C. Page, R. Herrera, and G. Nunez. Interleukin-3-induced Phosphorylation of BAD through the Protein Kinase Akt.
-
-
Del Peso, L.1
-
23
-
-
0028329953
-
-
Cell 76:1025-1037,1994.
-
Derijard, B., M. Hibi, I. H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-jun activation domain. Cell 76:1025-1037,1994.
-
M. Hibi, I. H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. JNK1: a Protein Kinase Stimulated by UV Light and Ha-Ras that Binds and Phosphorylates the C-jun Activation Domain.
-
-
Derijard, B.1
-
26
-
-
0027979447
-
-
J. Exp. Med. 179: 703708,1994.
-
Dubucquoi, S., P. Desreumaux, A. Janin, O. Klein, M. Goldman, J. Tavernier, A, Capron, and M. Capron. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J. Exp. Med. 179: 703708,1994.
-
P. Desreumaux, A. Janin, O. Klein, M. Goldman, J. Tavernier, A, Capron, and M. Capron. Interleukin 5 Synthesis by Eosinophils: Association with Granules and Immunoglobulin-dependent Secretion.
-
-
Dubucquoi, S.1
-
27
-
-
0026611951
-
-
Proc. Natl. Acad. Sei. USA 89:1587-1591,1992.
-
Duronio, V., M. J. Welham, S. Abraham, P. Dryden, and J. W. Schrader. p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein. Proc. Natl. Acad. Sei. USA 89:1587-1591,1992.
-
M. J. Welham, S. Abraham, P. Dryden, and J. W. Schrader. P21ras Activation via Hemopoietin Receptors and C-kit Requires Tyrosine Kinase Activity but not Tyrosine Phosphorylation of P21ras GTPase-activating Protein.
-
-
Duronio, V.1
-
29
-
-
33746749503
-
-
Prog. Immunol. 1: 355-368,1971.
-
Dutton, R. W., R. Falkoff, J. A, Hirst, M. Huffman, J. W. Kappler, J. R. Kettmann, J. F. Leseley, and D. Vann. Is there evidence for a non-antigen specific diffusable chemical mediator from the thymus-derived cell in the initiation of the immune response? Prog. Immunol. 1: 355-368,1971.
-
R. Falkoff, J. A, Hirst, M. Huffman, J. W. Kappler, J. R. Kettmann, J. F. Leseley, and D. Vann. Is There Evidence for a Non-antigen Specific Diffusable Chemical Mediator from the Thymus-derived Cell in the Initiation of the Immune Response?
-
-
Dutton, R.W.1
-
30
-
-
0024410530
-
-
Blood 73: 1809-1813,1989.
-
Enokihara, H., S. Furusawa, H. Nakakubo, H. Kajitani, S. Nagashima, K. Saito, H. Shishido, Y. Hitoshi, T. Noma, A. Shimizu, and T. Honjo. T cells from eosinophilic patients produce interleukin-5 with interleukin-2 stimulation. Blood 73: 1809-1813,1989.
-
S. Furusawa, H. Nakakubo, H. Kajitani, S. Nagashima, K. Saito, H. Shishido, Y. Hitoshi, T. Noma, A. Shimizu, and T. Honjo. T Cells from Eosinophilic Patients Produce Interleukin-5 with Interleukin-2 Stimulation.
-
-
Enokihara, H.1
-
31
-
-
0030930196
-
-
Blood 90:1768-1776,1997.
-
Feldman, G. M., L. A. Rosenthal, X. Liu, M. P. Hayes, A. Wynshaw-Boris, W. J. Leonard, L. Hennighausen, and D. S. Finbloom. STATSA-deficient mice demonstrate a defect in granulocyte-macrophage colony-stimulating factor-induced proliferation and gene expression. Blood 90:1768-1776,1997.
-
L. A. Rosenthal, X. Liu, M. P. Hayes, A. Wynshaw-Boris, W. J. Leonard, L. Hennighausen, and D. S. Finbloom. STATSA-deficient Mice Demonstrate a Defect in Granulocyte-macrophage Colony-stimulating Factor-induced Proliferation and Gene Expression.
-
-
Feldman, G.M.1
-
35
-
-
0027992342
-
-
J. Biol. Chem. 269: 5403-5412,1994.
-
Gold, M. R., V. Duronio, S. P. Saxena, J. W. Schrader, and R. Aebersold. Multiple cytokines activate phosphatidylinositol 3-kinase in hematopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. J. Biol. Chem. 269: 5403-5412,1994.
-
V. Duronio, S. P. Saxena, J. W. Schrader, and R. Aebersold. Multiple Cytokines Activate Phosphatidylinositol 3-kinase in Hematopoietic Cells. Association of the Enzyme with Various Tyrosine-phosphorylated Proteins.
-
-
Gold, M.R.1
-
37
-
-
0031056783
-
-
J. Cell Sei. 110:357-368,1997.
-
Guay, J., H. Lambert, G. Gingras-Breton, J. N. Lavoie, J. Huot, and J. Landry. Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein. J. Cell Sei. 110:357-368,1997.
-
H. Lambert, G. Gingras-Breton, J. N. Lavoie, J. Huot, and J. Landry. Regulation of Actin Filament Dynamics by P38 Map Kinase-mediated Phosphorylation of Heat Shock Protein.
-
-
Guay, J.1
-
39
-
-
0027413034
-
-
J. 12:1641-1646,1993.
-
Hanazono, Y., S. Chiba, K. Sasaki, H. Mano, A. Miyajima, K. Arai, Y. Yazaki, and H. Hirai. c-fps/fes protein tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3.EMBO J. 12:1641-1646,1993.
-
S. Chiba, K. Sasaki, H. Mano, A. Miyajima, K. Arai, Y. Yazaki, and H. Hirai. C-fps/fes Protein Tyrosine Kinase Is Implicated in a Signaling Pathway Triggered by Granulocyte-macrophage Colony-stimulating Factor and Interleukin-3.EMBO
-
-
Hanazono, Y.1
-
40
-
-
0030043033
-
-
Acta Haematol. 95: 236-242,1996.
-
Hanazono, Y., H. Odai, K. Sasaki, A. Iwamatsu, Y. Yazaki, and H. Hirai. Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells. Acta Haematol. 95: 236-242,1996.
-
H. Odai, K. Sasaki, A. Iwamatsu, Y. Yazaki, and H. Hirai. Proto-oncogene Products Vav and C-Cbl Are Involved in the Signal Transduction through Grb2/Ash in Hematopoietic Cells.
-
-
Hanazono, Y.1
-
41
-
-
0021813331
-
-
J. Immunol. 134:3944-3951,1985.
-
Harada, N., Y. Kikuchi, A. Tominaga, S. Takaki, and K. Takatsu. BCGFII activity on activated B cells of a purified murine T cell-replacing factor (TRF) from a T cell hybridoma (B151K12). J. Immunol. 134:3944-3951,1985.
-
Y. Kikuchi, A. Tominaga, S. Takaki, and K. Takatsu. BCGFII Activity on Activated B Cells of a Purified Murine T Cell-replacing Factor (TRF) from a T Cell Hybridoma (B151K12).
-
-
Harada, N.1
-
42
-
-
0028784215
-
-
Cell 83:301-311,1995.
-
Hibbs, M. L., D. M. Tarlinton, J. Armes, D. Grail, G. Hodgson, R. Maglitto, S. A. Stacker, and A. R. Dunn. Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell 83:301-311,1995.
-
D. M. Tarlinton, J. Armes, D. Grail, G. Hodgson, R. Maglitto, S. A. Stacker, and A. R. Dunn. Multiple Defects in the Immune System of Lyn-deficient Mice, Culminating in Autoimmune Disease.
-
-
Hibbs, M.L.1
-
43
-
-
0025149434
-
-
J. Exp. Med. 172: 1525-1528,1990.
-
Hirai, K., M. Yamaguchi, Y. Misaki, T. Takaishi, K. Ohta, Y. Morita, K. Ito, and T. Miyamoto. Enhancement of human basophil histamine release by interleukin 5. J. Exp. Med. 172: 1525-1528,1990.
-
M. Yamaguchi, Y. Misaki, T. Takaishi, K. Ohta, Y. Morita, K. Ito, and T. Miyamoto. Enhancement of Human Basophil Histamine Release by Interleukin 5.
-
-
Hirai, K.1
-
44
-
-
0027329865
-
-
Int. Immunol. 5: 11831190,1993.
-
Hitoshi, Y., E. Sonoda, Y. Kikuchi, S. Yonehara, H. Nakauchi, and K. Takatsu. IL-5 receptor positive B cells, but not eosinophils, are functionally and numerically influenced in mice carrying the X-linked immune defect. Int. Immunol. 5: 11831190,1993.
-
E. Sonoda, Y. Kikuchi, S. Yonehara, H. Nakauchi, and K. Takatsu. IL-5 Receptor Positive B Cells, but not Eosinophils, Are Functionally and Numerically Influenced in Mice Carrying the X-linked Immune Defect.
-
-
Hitoshi, Y.1
-
46
-
-
0030024851
-
-
Moraxella catarrhalis. J. Immunol. 156:1392-1401,1996.
-
Huston, M. M., J. P. Moore, H. J. Mettes, G. Tavana, and D. P. Huston. Human B cells express IL-5 receptor messenger ribonucleic acid and respond to IL-5 with enhanced IgM production after mitogenic stimulation with Moraxella catarrhalis. J. Immunol. 156:1392-1401,1996.
-
J. P. Moore, H. J. Mettes, G. Tavana, and D. P. Huston. Human B Cells Express IL-5 Receptor Messenger Ribonucleic Acid and Respond to IL-5 with Enhanced IgM Production after Mitogenic Stimulation with
-
-
Huston, M.M.1
-
48
-
-
0029056076
-
-
Proc. Natl. Acad. Sei. USA 92: 8665-8669,1995.
-
Inborn, R. C., N. Carlesso, M. Durstin, D. A. Frank, and J. D. Griffin. Identification of a viability domain in the granulocyte/macrophaage colony-stimulating factor receptor β-chain involving tyrosine-750. Proc. Natl. Acad. Sei. USA 92: 8665-8669,1995.
-
N. Carlesso, M. Durstin, D. A. Frank, and J. D. Griffin. Identification of a Viability Domain in the Granulocyte/macrophaage Colony-stimulating Factor Receptor β-Chain Involving Tyrosine-750.
-
-
Inborn, R.C.1
-
50
-
-
0029887634
-
-
J. Biol. Chem. 271: 7587-7592, 1996.
-
Itoh,T.,A.Muto, S. Watanabe, A. Miyajima, T. Yokota, and K. Aral. Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling. J. Biol. Chem. 271: 7587-7592, 1996.
-
A.Muto, S. Watanabe, A. Miyajima, T. Yokota, and K. Aral. Granulocyte-macrophage Colony-stimulating Factor Provokes RAS Activation and Transcription of C-fos through Different Modes of Signaling.
-
-
Itoh, T.1
-
54
-
-
0025034224
-
-
Blood 76: 706-715,1990.
-
Kanakura, Y., B. Druker, 8. A. Cannistra, Y. Furukawa, Y. Torimoto, and J. D. Griffin. Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins. Blood 76: 706-715,1990.
-
B. Druker, 8. A. Cannistra, Y. Furukawa, Y. Torimoto, and J. D. Griffin. Signal Transduction of the Human Granulocyte-macrophage Colony-stimulating Factor and Interleukin-3 Receptors Involves Tyrosine Phosphorylation of a Common Set of Cytoplasmic Proteins.
-
-
Kanakura, Y.1
-
55
-
-
0026061602
-
-
Blood 77: 243-248,1991.
-
Kanakura, Y., B. Druker, K. W. Wood, H. J. Mamon, K. Okuda, T. M. Roberts, and J. D. Griffin. Granulocytemacrophage colony-stimulating factor and interIeukin-3 induce rapid phosphorylation and activation of the proto-oncogene Raf-1 in a human factor-dependent myeloid cell line. Blood 77: 243-248,1991.
-
B. Druker, K. W. Wood, H. J. Mamon, K. Okuda, T. M. Roberts, and J. D. Griffin. Granulocytemacrophage Colony-stimulating Factor and InterIeukin-3 Induce Rapid Phosphorylation and Activation of the Proto-oncogene Raf-1 in a Human Factor-dependent Myeloid Cell Line.
-
-
Kanakura, Y.1
-
59
-
-
0026689659
-
-
J. Immunol. 149:629-635,1992.
-
Kita, H., D. A. Weiler, R. Abu-Ghazaleh, C. J. Sanderson, and G. J. Gleich. Release of granule proteins from eosinophils cultured with IL-5. J. Immunol. 149:629-635,1992.
-
D. A. Weiler, R. Abu-Ghazaleh, C. J. Sanderson, and G. J. Gleich. Release of Granule Proteins from Eosinophils Cultured with IL-5.
-
-
Kita, H.1
-
60
-
-
0029943605
-
-
Mol. Cell. Biol. 16: 41174127,1996.
-
KHppel, A., C. Reinhard, W. M. Kavanaugh, G. Apell, M. A. Escobedo, and L. T. Williams. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol. Cell. Biol. 16: 41174127,1996.
-
C. Reinhard, W. M. Kavanaugh, G. Apell, M. A. Escobedo, and L. T. Williams. Membrane Localization of Phosphatidylinositol 3-kinase Is Sufficient to Activate Multiple Signal-transducing Kinase Pathways.
-
-
Khppel, A.1
-
61
-
-
0028968362
-
-
Oncogene 10: 907-917, 1995.
-
Lanfrancone, L., G. Pelicci, M. F. Brizzi, M. G. Arouica, C. Casciari, S. Giuli, L. Pegoraro, T. Pawson, and P. G. Pelicci. Overexpression of She proteins potentiates the proliferative response to the granulocyte-macrophage colony-stimulating factor and recruitement of Grb2/Sos and Grb2/pl40 complexes to the βreceptor subunit. Oncogene 10: 907-917, 1995.
-
G. Pelicci, M. F. Brizzi, M. G. Arouica, C. Casciari, S. Giuli, L. Pegoraro, T. Pawson, and P. G. Pelicci. Overexpression of She Proteins Potentiates the Proliferative Response to the Granulocyte-macrophage Colony-stimulating Factor and Recruitement of Grb2/Sos and Grb2/pl40 Complexes to the βReceptor Subunit.
-
-
Lanfrancone, L.1
-
62
-
-
0031034517
-
-
Oncogene 14:425-430,1997.
-
Leverrier, Y., J. Thomas, G. R. Perkins, M. Mangeney, M. K. L. Collins, and J. Marvel. In bone marrow derived Baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways. Oncogene 14:425-430,1997.
-
J. Thomas, G. R. Perkins, M. Mangeney, M. K. L. Collins, and J. Marvel. in Bone Marrow Derived Baf-3 Cells, Inhibition of Apoptosis by IL-3 Is Mediated by Two Independent Pathways.
-
-
Leverrier, Y.1
-
63
-
-
0028979079
-
-
J. Immunol. 154:2165-2174,1995.
-
Li, Y., B. F. Shen, C. Karanes, L. Sensenbrenner, and B. Chen. Association between Lyn protein tyrosine kinase (p53/ 561yn) and the βsubunit of the granulocyte-macrophage colonystimulating factor (GM-CSF) receptors in a GM-CSF-dependent human megakaryocytic leukemia cell line (M-07e). J. Immunol. 154:2165-2174,1995.
-
B. F. Shen, C. Karanes, L. Sensenbrenner, and B. Chen. Association between Lyn Protein Tyrosine Kinase (P53/ 561yn) and the βSubunit of the Granulocyte-macrophage Colonystimulating Factor (GM-CSF) Receptors in a GM-CSF-dependent Human Megakaryocytic Leukemia Cell Line (M-07e).
-
-
Li, Y.1
-
64
-
-
0028337425
-
-
Blood 84:94-103,1994.
-
Linnekin, D., O. M. Howard, L. Park, W. Farrar, D. Ferris, and D. L. Longo. Hck expression correlates with granulocytemacrophage colony-stimulating factor-induced proliferation in HL-60 cells. Blood 84:94-103,1994.
-
O. M. Howard, L. Park, W. Farrar, D. Ferris, and D. L. Longo. Hck Expression Correlates with Granulocytemacrophage Colony-stimulating Factor-induced Proliferation in HL-60 Cells.
-
-
Linnekin, D.1
-
66
-
-
0025007062
-
-
J. Cell. Physiol. 145: 69-77,1990.
-
Lopez, A. F., J. M. Eglinton, A. B. Lyons, P. M. Tapley, L. B. To, L. S. Park, S. C. Clark, and M. A. Vadas. Human interleukin-3 inhibits the binding of granulocyte-macrophage colony-stimulating factor and interleukin-5 to basophils and strongly enhances their functional activity. J. Cell. Physiol. 145: 69-77,1990.
-
J. M. Eglinton, A. B. Lyons, P. M. Tapley, L. B. To, L. S. Park, S. C. Clark, and M. A. Vadas. Human Interleukin-3 Inhibits the Binding of Granulocyte-macrophage Colony-stimulating Factor and Interleukin-5 to Basophils and Strongly Enhances Their Functional Activity.
-
-
Lopez, A.F.1
-
67
-
-
0023879839
-
-
J. Exp. Med. 167:219-224,1988.
-
Lopez, A. F., C. J. Sanderson, J. R. Gamble, H. D. Campbell, I. G. Young, and M. A. Vadas. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167:219-224,1988.
-
C. J. Sanderson, J. R. Gamble, H. D. Campbell, I. G. Young, and M. A. Vadas. Recombinant Human Interleukin 5 Is a Selective Activator of Human Eosinophil Function.
-
-
Lopez, A.F.1
-
70
-
-
0028985012
-
-
EMBO J. 14: 257-265,1995.
-
Matsuguchi, T., R. C. Inborn, N. Carlesso, G. Xu, B. Druker, and J. D. Griffin. Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL. EMBO J. 14: 257-265,1995.
-
R. C. Inborn, N. Carlesso, G. Xu, B. Druker, and J. D. Griffin. Tyrosine Phosphorylation of P95Vav in Myeloid Cells Is Regulated by GM-CSF, IL-3 and Steel Factor and Is Constitutively Increased by P210BCR/ABL.
-
-
Matsuguchi, T.1
-
71
-
-
0027939947
-
-
J. Biol. Chem. 269: 5016-5021, 1994.
-
Matsuguchi, T., R. Salgia, M. Hallek, M. Eder, B. Druker, T. J. Ernst, and J. D. Griffin. She phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL. J. Biol. Chem. 269: 5016-5021, 1994.
-
R. Salgia, M. Hallek, M. Eder, B. Druker, T. J. Ernst, and J. D. Griffin. She Phosphorylation in Myeloid Cells Is Regulated by Granulocyte Macrophage Colony-stimulating Factor, Interleukin-3, and Steel Factor and Is Constitutively Increased by P210BCR/ABL.
-
-
Matsuguchi, T.1
-
72
-
-
0027489710
-
-
Blood 82: 1960-1974, 1993.
-
Miyajima, A., A. L. Mui, T. Ogorochi, and K. Sakamaki. Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5. Blood 82: 1960-1974, 1993.
-
A. L. Mui, T. Ogorochi, and K. Sakamaki. Receptors for Granulocyte-macrophage Colony-stimulating Factor, Interleukin-3, and Interleukin-5.
-
-
Miyajima, A.1
-
73
-
-
0027316959
-
-
Cell. Immunol. 149:390-401,1993.
-
Morikawa, K., F. Oseko, S. Morikawa, K. Imai, and M. Sawada. Recombinant human IL-5 augments immunoglobulin generation by human B lymphocytes in the presence of IL-2. Cell. Immunol. 149:390-401,1993.
-
F. Oseko, S. Morikawa, K. Imai, and M. Sawada. Recombinant Human IL-5 Augments Immunoglobulin Generation by Human B Lymphocytes in the Presence of IL-2.
-
-
Morikawa, K.1
-
75
-
-
0028963550
-
-
liomologs.EMBOJ. 14:1166-1175,1995.
-
Mui, A. L., H. Wakao, A, M. O'Farrell, N. Harada, and A. Miyajima. Interleukin-3, granulocyte-macrophage colonystimulating factor and interleukin-5 transduce signals through two STATS liomologs.EMBOJ. 14:1166-1175,1995.
-
H. Wakao, A, M. O'Farrell, N. Harada, and A. Miyajima. Interleukin-3, Granulocyte-macrophage Colonystimulating Factor and Interleukin-5 Transduce Signals through Two STATS
-
-
Mui, A.L.1
-
76
-
-
0029892399
-
-
EMBO J. 15:2425-2433,1996.
-
Mui, A. L., H. Wakao, T. Kinoshita, T. Kitamura, and A. Miyajima. Suppression of interleukin-3-induced gene expression by a C-terminal truncated StatS: role of StatS in proliferation. EMBO J. 15:2425-2433,1996.
-
H. Wakao, T. Kinoshita, T. Kitamura, and A. Miyajima. Suppression of Interleukin-3-induced Gene Expression by a C-terminal Truncated StatS: Role of StatS in Proliferation.
-
-
Mui, A.L.1
-
77
-
-
0026338754
-
-
Proc. Nail. Acad. Sei. USA 88: 11349-11353,1991.
-
Murakami, M., M. Narazaki, M. Hihi, H. Yawata, K. Yasukawa, M. Hamaguchi, T. Taga, and T. Kishimoto. Critical region of the IL-6 signal transducer gplSO is conserved in the cytokine receptor family. Proc. Nail. Acad. Sei. USA 88: 11349-11353,1991.
-
M. Narazaki, M. Hihi, H. Yawata, K. Yasukawa, M. Hamaguchi, T. Taga, and T. Kishimoto. Critical Region of the IL-6 Signal Transducer GplSO Is Conserved in the Cytokine Receptor Family.
-
-
Murakami, M.1
-
80
-
-
0030945261
-
-
Blood 89:2664-2669,1997.
-
Nagata, Y., E. Nishida, and K. Todokoro. Activation of JNK signaling pathway by erythropoietin, thrombopoietin, and interleukin-3. Blood 89:2664-2669,1997.
-
E. Nishida, and K. Todokoro. Activation of JNK Signaling Pathway by Erythropoietin, Thrombopoietin, and Interleukin-3.
-
-
Nagata, Y.1
-
81
-
-
0029967128
-
-
Biochem. Biophys. Res. Commun. 221:785-789,1996.
-
Nagata, Y., and K. Todokoro. Interleukin 3 activates not only JAK2 and STATS, but also Tyk2, STAT1, and STATS. Biochem. Biophys. Res. Commun. 221:785-789,1996.
-
And K. Todokoro. Interleukin 3 Activates not only JAK2 and STATS, but also Tyk2, STAT1, and STATS.
-
-
Nagata, Y.1
-
83
-
-
0027535742
-
-
J. Biol. Chem. 268:13-16,1993.
-
Nakanishi, H., K. A. Brewer, and J. H. Exton. Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-triphosphate. J. Biol. Chem. 268:13-16,1993.
-
K. A. Brewer, and J. H. Exton. Activation of the Zeta Isozyme of Protein Kinase C by Phosphatidylinositol 3,4,5-triphosphate.
-
-
Nakanishi, H.1
-
84
-
-
0023176706
-
-
Immunol. Lett. 15:249-253,1987.
-
Noma, T., T. Mizuta, A. Rosen, T. Hirano, T. Kishimoto, and T. Honjo. Enhancement of the interleukin 2 receptor expression on T cells by multiple B-lymphotropic lymphokines. Immunol. Lett. 15:249-253,1987.
-
T. Mizuta, A. Rosen, T. Hirano, T. Kishimoto, and T. Honjo. Enhancement of the Interleukin 2 Receptor Expression on T Cells by Multiple B-lymphotropic Lymphokines.
-
-
Noma, T.1
-
85
-
-
0031000904
-
-
Blood 89:2745-2756,1997.
-
Odai, H., K. Sasaki, A. Iwamatsu, T. Nakamoto, H. Ueno, T. Yamagata, K. Miiani, Y. Yazaki, and H. Hirai. Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signal-ing pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl. Blood 89:2745-2756,1997.
-
K. Sasaki, A. Iwamatsu, T. Nakamoto, H. Ueno, T. Yamagata, K. Miiani, Y. Yazaki, and H. Hirai. Purification and Molecular Cloning of SH2- and SH3-containing Inositol Polyphosphate-5-phosphatase, which Is Involved in the Signal-ing Pathway of Granulocyte-macrophage Colony-stimulating Factor, Erythropoietin, and Bcr-Abl.
-
-
Odai, H.1
-
86
-
-
0032055856
-
-
Blood 91: 2264-2271,1998.
-
Ogata, N., T. Kouro, A. Yamacla, M. Koike, N. Hanai, T. Ishikawa, and K. Takatsu. JAK2 and JAK1 constitutively associate with an interloukin-5 (IL-5) receptor a and βc subunit, respectively, and are activated upon IL-5 stimulation. Blood 91: 2264-2271,1998.
-
T. Kouro, A. Yamacla, M. Koike, N. Hanai, T. Ishikawa, and K. Takatsu. JAK2 and JAK1 Constitutively Associate with an Interloukin-5 (IL-5) Receptor a and βC Subunit, Respectively, and Are Activated upon IL-5 Stimulation.
-
-
Ogata, N.1
-
87
-
-
0026753999
-
-
Blood 79:2880-2887,1992.
-
Okuda, K, J. S. Sanghera, S. L. Pelech, Y. Kanakura, M. Hallek, J. D. Griffin, and B. J. Druker. Granulocytemacrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase. Blood 79:2880-2887,1992.
-
J. S. Sanghera, S. L. Pelech, Y. Kanakura, M. Hallek, J. D. Griffin, and B. J. Druker. Granulocytemacrophage Colony-stimulating Factor, Interleukin-3, and Steel Factor Induce Rapid Tyrosine Phosphorylation of P42 and P44 MAP Kinase.
-
-
Okuda, K.1
-
88
-
-
0024356310
-
-
Exp. Med. 170:343-348,1989.
-
Owen, W. F., M. E. Rothenberg, J. Petersen, P. F. Weller, D. Silberstein, A. L. Sheffer, R. L. Stevens, R. J. Soberman, and K. F. Austen. Interleukin 5 and phenotypically altered eosinophils in the blood of patients with the idiopathic hypereosinophilic syndrome. J. Exp. Med. 170:343-348,1989.
-
M. E. Rothenberg, J. Petersen, P. F. Weller, D. Silberstein, A. L. Sheffer, R. L. Stevens, R. J. Soberman, and K. F. Austen. Interleukin 5 and Phenotypically Altered Eosinophils in the Blood of Patients with the Idiopathic Hypereosinophilic Syndrome. J.
-
-
Owen, W.F.1
-
89
-
-
85177151154
-
-
J. Biol. Chem. 270:15942-15945,1995.
-
Pallard, C., F. Gouilleux, M. Charon, B. Groner, S. Gisselbrecht, and I. Dusanter-Fourt. Interleukin-3, erythropoietin, and prolactin activate STAT5-like factor in lymphoid cells. J. Biol. Chem. 270:15942-15945,1995.
-
F. Gouilleux, M. Charon, B. Groner, S. Gisselbrecht, and I. Dusanter-Fourt. Interleukin-3, Erythropoietin, and Prolactin Activate STAT5-like Factor in Lymphoid Cells.
-
-
Pallard, C.1
-
91
-
-
0028881246
-
-
J. Immunol. 155:4454-4458,1995.
-
Pazdrak, K., L. Justement, and R. Alam. Mechanism of inhibition of eosinophil activation by transforming growth factor-β. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor. J. Immunol. 155:4454-4458,1995.
-
L. Justement, and R. Alam. Mechanism of Inhibition of Eosinophil Activation by Transforming Growth Factor-β. Inhibition of Lyn, MAP, Jak2 Kinases and STAT1 Nuclear Factor.
-
-
Pazdrak, K.1
-
92
-
-
33746753451
-
-
J. Exp. Med. In press.
-
Pazdrak, K, B. Olszewska-Pazdrak, S. Stafford, R. Garofalo, and R. Alam. Lyn, Jak2 and Raf-1 kinases are critical for the anti-apoptotic effect of interleukin-5 whereas only Raf-1 kinase is essential for eosinophil activation and degranulation. J. Exp. Med. In press.
-
B. Olszewska-Pazdrak, S. Stafford, R. Garofalo, and R. Alam. Lyn, Jak2 and Raf-1 Kinases Are Critical for the Anti-apoptotic Effect of Interleukin-5 whereas only Raf-1 Kinase Is Essential for Eosinophil Activation and Degranulation.
-
-
Pazdrak, K.1
-
93
-
-
0028956998
-
-
J. Exp. Med. 181: 1827-1834, 1995.
-
Pazdrak, K., D. Schreiber, P. Forsythe, L. Justement, and R. Alam. The signal transduction mechanism of IL-5 in eosinophils: the involvement of lyn tyrosine kinase and the ras-raf 1-MEK-MAP kinase pathway. J. Exp. Med. 181: 1827-1834, 1995.
-
D. Schreiber, P. Forsythe, L. Justement, and R. Alam. the Signal Transduction Mechanism of IL-5 in Eosinophils: the Involvement of Lyn Tyrosine Kinase and the Ras-raf 1-MEK-MAP Kinase Pathway.
-
-
Pazdrak, K.1
-
97
-
-
0029939507
-
-
J. Biol Chem. 271:12137-12140,1996.
-
Pratt, J. C., M. Weiss, C. A. Sieff, S. E. Shoelson, S. J. Burakoff, and K. S. Ravichandran. Evidence for a physical association between the Shc-PTB domain and the βc chain of the granulocyte-macrophage colony-stimulating factor receptor. J. Biol Chem. 271:12137-12140,1996.
-
M. Weiss, C. A. Sieff, S. E. Shoelson, S. J. Burakoff, and K. S. Ravichandran. Evidence for a Physical Association between the Shc-PTB Domain and the βC Chain of the Granulocyte-macrophage Colony-stimulating Factor Receptor.
-
-
Pratt, J.C.1
-
98
-
-
0028180569
-
-
Mol. Cell. Biol. 14:4335-4341,1994.
-
Quelle, F. W., N. Sato, B. A. Witthuhn, R. Inhorn, M. Eder, A. Miyajima, J. D. Griffin, and J. N. Ihle. Jak2 associates with the βc chain of the receptor for granulocyte-macropharge colony-stimulating factor, and its activation requires the membrane-proximal region. Mol. Cell. Biol. 14:4335-4341,1994.
-
N. Sato, B. A. Witthuhn, R. Inhorn, M. Eder, A. Miyajima, J. D. Griffin, and J. N. Ihle. Jak2 Associates with the βC Chain of the Receptor for Granulocyte-macropharge Colony-stimulating Factor, and Its Activation Requires the Membrane-proximal Region.
-
-
Quelle, F.W.1
-
99
-
-
0029057858
-
-
Mol. Cell. Biol. 15:3336-3343,1995.
-
Quelle, F. W., K. Shimoda, W. Thierfelder, C. Fisher, A. Kim, S. M. Rubin, J. L. Cleveland, J. H. Pierce, A. D. Keegan, K. Nelms, W. E. Paul, and J. N. Ihle. Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine ! phosphorylated in response to IL-4 and IL-3 but are not required for mitogenesis. Mol. Cell. Biol. 15:3336-3343,1995.
-
K. Shimoda, W. Thierfelder, C. Fisher, A. Kim, S. M. Rubin, J. L. Cleveland, J. H. Pierce, A. D. Keegan, K. Nelms, W. E. Paul, and J. N. Ihle. Cloning of Murine Stat6 and Human Stat6, Stat Proteins that Are Tyrosine ! Phosphorylated in Response to IL-4 and IL-3 but Are not Required for Mitogenesis.
-
-
Quelle, F.W.1
-
101
-
-
0029961352
-
-
Blood 88: 2906-! 2916,1996.
-
Rajotte, D., H. B. Sadowski, A. Haman, K. Gopalbhai, S. Meloche, L. Liu, G. Krystal, and T. Hoang. Contribution of both STAT and SRF/TCF to c-/os promoter activation by granu[ locyte-macrophage colony-stimulating factor. Blood 88: 2906-! 2916,1996.
-
H. B. Sadowski, A. Haman, K. Gopalbhai, S. Meloche, L. Liu, G. Krystal, and T. Hoang. Contribution of both STAT and SRF/TCF to C-/os Promoter Activation by Granu Locyte-macrophage Colony-stimulating Factor.
-
-
Rajotte, D.1
-
103
-
-
0027305921
-
-
S. Tsukada, D. A. Largaespada, J. C. Grimaldi, L. Cohen, R. N. Mohr, J. F. Bazan, M. Howard, N. G. Copeland, N. A. Jerkins, and O. N. Witte. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science 261: 358-361, 1993.
-
Rawlings, D. J., D. C. Saffran, S. Tsukada, D. A. Largaespada, J. C. Grimaldi, L. Cohen, R. N. Mohr, J. F. Bazan, M. Howard, N. G. Copeland, N. A. Jerkins, and O. N. Witte. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science 261: 358-361, 1993.
-
D. C. Saffran
-
-
Rawlings, D.J.1
-
105
-
-
0024330415
-
-
J. Immunol. -143:2311-2316,1989.
-
Rothenberg, M. E., J. Petersen, R. L. Stevens, D. S. Silberstein, D. T. McKenzie, K. F. Austen, and W. F. Owen. IL-5-dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity, and sustained antibodydependent cytotoxicity. J. Immunol. -143:2311-2316,1989.
-
J. Petersen, R. L. Stevens, D. S. Silberstein, D. T. McKenzie, K. F. Austen, and W. F. Owen. IL-5-dependent Conversion of Normodense Human Eosinophils to the Hypodense Phenotype Uses 3T3 Fibroblasts for Enhanced Viability, Accelerated Hypodensity, and Sustained Antibodydependent Cytotoxicity.
-
-
Rothenberg, M.E.1
-
107
-
-
0027494821
-
-
EMBO J. 12: 4181-4189, 1993.
-
Sato, N., K. Sakamaki, N. Terada, K. Arai, and A. Miyajima. Signal transduction by the high-affinity GM-CSF recep- ! tor: two distinct cytoplasmic regions of the common βsubunit responsible for different signaling. EMBO J. 12: 4181-4189, 1993.
-
K. Sakamaki, N. Terada, K. Arai, and A. Miyajima. Signal Transduction by the High-affinity GM-CSF Recep- ! Tor: Two Distinct Cytoplasmic Regions of the Common βSubunit Responsible for Different Signaling.
-
-
Sato, N.1
-
108
-
-
0028114191
-
-
J. Exp. Med. 180: 2101-2111,1994.
-
Sato, S., T. Katagiri, S. Takaki, Y. Kikuchi, Y. Hitoshi, S. Yonehara, S. Tsukada, D. Kitamura, T. Watanabe, O. Witte, and K. Takatsu. IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases. J. Exp. Med. 180: 2101-2111,1994.
-
T. Katagiri, S. Takaki, Y. Kikuchi, Y. Hitoshi, S. Yonehara, S. Tsukada, D. Kitamura, T. Watanabe, O. Witte, and K. Takatsu. IL-5 Receptor-mediated Tyrosine Phosphorylation of SH2/SH3-containing Proteins and Activation of Bruton's Tyrosine and Janus 2 Kinases.
-
-
Sato, S.1
-
109
-
-
0026345291
-
-
Proc. Natl. Acad. Sei. USA 88:3314-3318,1991.
-
Satoh, T., M. Nakafuku, A. Miyajima, and Y. Kaziro. Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and grariulocyte/macrophage colony-stimulating factor, but not from interleukin 4. Proc. Natl. Acad. Sei. USA 88:3314-3318,1991.
-
M. Nakafuku, A. Miyajima, and Y. Kaziro. Involvement of Ras P21 Protein in Signal-transduction Pathways from Interleukin 2, Interleukin 3, and Grariulocyte/macrophage Colony-stimulating Factor, but not from Interleukin 4.
-
-
Satoh, T.1
-
112
-
-
0030831869
-
-
J. Clin. Invest. 100:2466-2475,1997.
-
Sehmi, R., L. J. Wood, R. Watson, R. Foley, Q. Hamid, P. M. O'Byrne, and J. A. Denburg. Allergen-induced increases in IL-5 receptor a-subunit expression on bone marrow-derived CD34'1 cells from asthmatic subjects: a novel marker of progenitor cell commitment towards eosinophilic differentiation. J. Clin. Invest. 100:2466-2475,1997.
-
L. J. Wood, R. Watson, R. Foley, Q. Hamid, P. M. O'Byrne, and J. A. Denburg. Allergen-induced Increases in IL-5 Receptor A-subunit Expression on Bone Marrow-derived CD34'1 Cells from Asthmatic Subjects: a Novel Marker of Progenitor Cell Commitment towards Eosinophilic Differentiation.
-
-
Sehmi, R.1
-
113
-
-
0027248709
-
-
Proc. Natl. Acad. Sei. USA 90:8429-8433,1993.
-
Silvennoinen, O., B. A. Witthuhn, F. W. Quelle, J. L. Cleveland, T. Yi, and J. N. Ihle. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. Proc. Natl. Acad. Sei. USA 90:8429-8433,1993.
-
B. A. Witthuhn, F. W. Quelle, J. L. Cleveland, T. Yi, and J. N. Ihle. Structure of the Murine Jak2 Protein-tyrosine Kinase and Its Role in Interleukin 3 Signal Transduction.
-
-
Silvennoinen, O.1
-
114
-
-
0024520902
-
-
Blood 73:406-418,1989.
-
Sorensen, P. H., A. L. Mui, S. C. Murthy, and G. Krystal. Interleukin-3, GM-CSF, and TEA induce distinct phosphorylation events in an interleukin 3-dependent multipotential cell line. Blood 73:406-418,1989.
-
A. L. Mui, S. C. Murthy, and G. Krystal. Interleukin-3, GM-CSF, and TEA Induce Distinct Phosphorylation Events in an Interleukin 3-dependent Multipotential Cell Line.
-
-
Sorensen, P.H.1
-
115
-
-
0028291525
-
-
Cell 77:727-736,1994.
-
Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. JNK is involved in signaling integration during costimulation of T lymphocytes. Cell 77:727-736,1994.
-
E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. JNK Is Involved in Signaling Integration during Costimulation of T Lymphocytes.
-
-
Su, B.1
-
116
-
-
0020557435
-
-
J. Exp. Med. 158:822-835,1983.
-
Swaim, S. L., M. Howard, J. Kappler, P. Marrack, J. Watson, R. Booth, G. D. Wetzel, W. E. Paul, and R. W. Dutton. Evidence for two distinct classes of murine B cell growth factors which have activities in different functional assays. J. Exp. Med. 158:822-835,1983.
-
M. Howard, J. Kappler, P. Marrack, J. Watson, R. Booth, G. D. Wetzel, W. E. Paul, and R. W. Dutton. Evidence for Two Distinct Classes of Murine B Cell Growth Factors which Have Activities in Different Functional Assays.
-
-
Swaim, S.L.1
-
117
-
-
0030926348
-
-
Oncogene 14:2273-2282,1997.
-
Takahashi-Tezuka, M., M. Hibi, Y. Fujitani, T. Fukuda, T. Yamaguchi, and T. Hirano. Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK. Oncogene 14:2273-2282,1997.
-
M. Hibi, Y. Fujitani, T. Fukuda, T. Yamaguchi, and T. Hirano. Tec Tyrosine Kinase Links the Cytokine Receptors to PI-3 Kinase Probably through JAK.
-
-
Takahashi-Tezuka, M.1
-
118
-
-
0027155237
-
-
J. Exp. Med. 177: 1523-1529,1993.
-
Takaki, S., Y. Murata, T. Kitamura, A. Miyajima, A. Tominaga, and K. Takatsu. Reconstitution of the functional receptors for murine and human interleukin 5. J. Exp. Med. 177: 1523-1529,1993.
-
Y. Murata, T. Kitamura, A. Miyajima, A. Tominaga, and K. Takatsu. Reconstitution of the Functional Receptors for Murine and Human Interleukin 5.
-
-
Takaki, S.1
-
120
-
-
0022642580
-
-
Immunol. 136:1161-1170,1986.
-
Takatsu, K., Y. Kikuchi, T. Kanatani, K. Okuno, T. Hamaoka, A. Tominaga, and Y. Sano. Generation of cytotoxic T lymphocytes from thymocyte precursors to trinitrophenylmodified self antigens. I. Requirement of both killer-helper factor(s) and interleukin-2 for CTL generation from a subpopulationof thymocytes. J. Immunol. 136:1161-1170,1986.
-
Y. Kikuchi, T. Kanatani, K. Okuno, T. Hamaoka, A. Tominaga, and Y. Sano. Generation of Cytotoxic T Lymphocytes from Thymocyte Precursors to Trinitrophenylmodified Self Antigens. I. Requirement of both Killer-helper Factor(s) and Interleukin-2 for CTL Generation from a Subpopulationof Thymocytes. J.
-
-
Takatsu, K.1
-
121
-
-
0344019003
-
-
Proc. Natl. Acad. Sei. USA 84: 4234-4238,1987.
-
Takatsu, K., Y. Kikuchi, T. Takahashi, T. Honjo, M. Matsumoto, N. Harada, N. Yamaguchi, and A. Tominaga. Interleukin 5, a T-cell-derived B-cell differentiation factor also induces cytotoxic T lymphocytes. Proc. Natl. Acad. Sei. USA 84: 4234-4238,1987.
-
Y. Kikuchi, T. Takahashi, T. Honjo, M. Matsumoto, N. Harada, N. Yamaguchi, and A. Tominaga. Interleukin 5, a T-cell-derived B-cell Differentiation Factor also Induces Cytotoxic T Lymphocytes.
-
-
Takatsu, K.1
-
123
-
-
85177003087
-
-
J. Biol. Chem. 270: 6523-6530,1995.
-
Tanner, J. W., W. Chen, R. L. Young, G. D. Longmore, and A, S. Shaw. The conserved box 1 motif of cytokine receptors is required for association with JAK kinases. J. Biol. Chem. 270: 6523-6530,1995.
-
W. Chen, R. L. Young, G. D. Longmore, and A, S. Shaw. the Conserved Box 1 Motif of Cytokine Receptors Is Required for Association with JAK Kinases.
-
-
Tanner, J.W.1
-
126
-
-
0027261447
-
-
Science 261:355-358,1993.
-
Thomas, J. D., P. Sidéras, C. I. Smith, I. Vorechovsky, V. Chapman, and W. E. Paul. Colocalization of X-linked aggamaglobulinemia and X-linked immunodeficiency genes. Science 261:355-358,1993.
-
P. Sidéras, C. I. Smith, I. Vorechovsky, V. Chapman, and W. E. Paul. Colocalization of X-linked Aggamaglobulinemia and X-linked Immunodeficiency Genes.
-
-
Thomas, J.D.1
-
127
-
-
85177016455
-
-
J. Biol. Chem. 269:32358-32367,1994.
-
Toker, A., M. Meyer, K. K. Reddy, J. R. Falck, R. Aneja, S. Aneja, A. Parra, D. J. Burns, L. M. Ballas, and L. C. Cantley. Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3. J. Biol. Chem. 269:32358-32367,1994.
-
M. Meyer, K. K. Reddy, J. R. Falck, R. Aneja, S. Aneja, A. Parra, D. J. Burns, L. M. Ballas, and L. C. Cantley. Activation of Protein Kinase C Family Members by the Novel Polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.
-
-
Toker, A.1
-
129
-
-
0028953733
-
-
Blood 85:1442-1448,1995.
-
Van der Bruggen, T., E. Caldenhoven, D. Kanters, P. Coffer, J. A. Raaijmakers, J. W. Lammers, and L. Koenderman. Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and STATla. Blood 85:1442-1448,1995.
-
E. Caldenhoven, D. Kanters, P. Coffer, J. A. Raaijmakers, J. W. Lammers, and L. Koenderman. Interleukin-5 Signaling in Human Eosinophils Involves JAK2 Tyrosine Kinase and STATla.
-
-
Van Der Bruggen, T.1
-
130
-
-
33746709441
-
-
Immunology 71: 258265,1990.
-
Walsh, G. M., A. Hartnell, A. J. Wardlaw, K. Kurihara, C. J. Sanderson, and A. B. Kay. IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leukocyte integrin (CDll/18)-dependent manner. Immunology 71: 258265,1990.
-
A. Hartnell, A. J. Wardlaw, K. Kurihara, C. J. Sanderson, and A. B. Kay. IL-5 Enhances the in Vitro Adhesion of Human Eosinophils, but not Neutrophils, in a Leukocyte Integrin (CDll/18)-dependent Manner.
-
-
Walsh, G.M.1
-
132
-
-
0024323740
-
-
Eur. J. Immu- ! nol. 19: 701-705,1989.
-
Wang, J. M., A. Rambaldi, A. Biondi, Z. G. Chen, C. J. Sanderson, and A. Mantovani. Recombinant human interleukin 5 is a sélective eosinophil chemoattractant. Eur. J. Immu- ! nol. 19: 701-705,1989.
-
A. Rambaldi, A. Biondi, Z. G. Chen, C. J. Sanderson, and A. Mantovani. Recombinant Human Interleukin 5 Is a Sélective Eosinophil Chemoattractant.
-
-
Wang, J.M.1
-
133
-
-
15844389026
-
-
c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor in BAT3 cells. J. Biol. Chem. 271: 12681-12686, 1996.
-
Watanabe, S., T. Itoh, and K. Arai. Jak2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor in BAT3 cells. J. Biol. Chem. 271: 12681-12686, 1996.
-
T. Itoh, and K. Arai. Jak2 Is Essential for Activation of
-
-
Watanabe, S.1
-
134
-
-
0026671246
-
-
J. Immunol. 149:1683-1693,1992.
-
Welham, M. J., V. Duronio, J. S. Sanghera, S. L. Pelech, and J. W. Schrader. Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members. J. Immunol. 149:1683-1693,1992.
-
V. Duronio, J. S. Sanghera, S. L. Pelech, and J. W. Schrader. Multiple Hemopoietic Growth Factors Stimulate Activation of Mitogen-activated Protein Kinase Family Members.
-
-
Welham, M.J.1
-
135
-
-
0028068607
-
-
J. Biol. Chem. 269: 2376423768,1994.
-
Welham, M. J., U. Dechert, K. B. Leslie, F. Jirik, and J. W. Schrader. Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3'-kinase. J. Biol. Chem. 269: 2376423768,1994.
-
U. Dechert, K. B. Leslie, F. Jirik, and J. W. Schrader. Interleukin (IL)-3 and Granulocyte/macrophage Colony-stimulating Factor, but not IL-4, Induce Tyrosine Phosphorylation, Activation, and Association of SHPTP2 with Grb2 and Phosphatidylinositol 3'-kinase.
-
-
Welham, M.J.1
-
137
-
-
0029954969
-
-
Proc. Natl. Acad. Sei. USA 93:11681-11686,1996.
-
Xia, K., N. K. Mukhopadhyay, R. C. Inborn, D. L. Barber, P. E. Rose, R. S. Lee, R. P. Narsimhan, A. D. D'Andréa, J. D. Griffin, and T. M. Roberts. The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner. Proc. Natl. Acad. Sei. USA 93:11681-11686,1996.
-
N. K. Mukhopadhyay, R. C. Inborn, D. L. Barber, P. E. Rose, R. S. Lee, R. P. Narsimhan, A. D. D'Andréa, J. D. Griffin, and T. M. Roberts. the Cytokine-activated Tyrosine Kinase JAK2 Activates Raf-1 in a P21ras-dependent Manner.
-
-
Xia, K.1
-
138
-
-
0029913802
-
-
J. Exp. Med. 183:1407-1414,1996.
-
Yousefi, S., D. C. Hoessli, K. Blaser, G. B. Mills, and H. U. Simon. Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokine in human eosinophils. J. Exp. Med. 183:1407-1414,1996.
-
D. C. Hoessli, K. Blaser, G. B. Mills, and H. U. Simon. Requirement of Lyn and Syk Tyrosine Kinases for the Prevention of Apoptosis by Cytokine in Human Eosinophils.
-
-
Yousefi, S.1
-
139
-
-
0030584088
-
-
Cell 87:619-628,1996.
-
Zha, J., H. Harada, E. Yang, J. Jockei, and S. J. Korsmeyer. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not Bcl-XL. Cell 87:619-628,1996.
-
H. Harada, E. Yang, J. Jockei, and S. J. Korsmeyer. Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 not Bcl-XL.
-
-
Zha, J.1
-
140
-
-
0028942656
-
-
Science 267:1990-1994,1995. .
-
Zhang, X., J. Blenis, H.-C. Li, C. Schindler, and S. ChenKiang. Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science 267:1990-1994,1995. .
-
J. Blenis, H.-C. Li, C. Schindler, and S. ChenKiang. Requirement of
-
-
Zhang, X.1
|