-
2
-
-
9644289522
-
Aging and gastrointestinal smooth muscle
-
Bitar KN, Patil SB. Aging and gastrointestinal smooth muscle. Mech Ageing Dev 2004; 125: 907-10.
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 907-910
-
-
Bitar, K.N.1
Patil, S.B.2
-
3
-
-
79955892537
-
Effect of aging on gastrointestinal function
-
Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, eds., 6th edn. New York, NY: McGraw-Hill
-
Hall K. Effect of aging on gastrointestinal function. In: Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, eds. Hazzard's: Geriatric Medicine & Gerontology, 6th edn. New York, NY: McGraw-Hill, 2009; 1059-64.
-
(2009)
Hazzard's: Geriatric Medicine & Gerontology
, pp. 1059-1064
-
-
Hall, K.1
-
4
-
-
55049123496
-
The clinical significance of gastrointestinal changes with aging
-
Bhutto A, Morley JE. The clinical significance of gastrointestinal changes with aging. Curr Opin Clin Nutr Metab Care 2008; 11: 651-60.
-
(2008)
Curr Opin Clin Nutr Metab Care
, vol.11
, pp. 651-660
-
-
Bhutto, A.1
Morley, J.E.2
-
5
-
-
0036093892
-
Gastrointestinal motility problems in the elderly patient
-
Firth M, Prather CM. Gastrointestinal motility problems in the elderly patient. Gastroenterology 2002; 122: 1688-700.
-
(2002)
Gastroenterology
, vol.122
, pp. 1688-1700
-
-
Firth, M.1
Prather, C.M.2
-
6
-
-
33644970942
-
Effect of aging on bolus kinematics during the pharyngeal phase of swallowing
-
Bardan E, Kern M, Arndorfer RC, Hofmann C, Shaker R. Effect of aging on bolus kinematics during the pharyngeal phase of swallowing. Am J Physiol Gastrointest Liver Physiol 2006; 290: G458-65.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Bardan, E.1
Kern, M.2
Arndorfer, R.C.3
Hofmann, C.4
Shaker, R.5
-
7
-
-
0030894035
-
Mechanisms involved in postdeglutition retention in the elderly
-
Dejaeger E, Pelemans W, Ponette E, Joosten E. Mechanisms involved in postdeglutition retention in the elderly. Dysphagia 1997; 12: 63-7.
-
(1997)
Dysphagia
, vol.12
, pp. 63-67
-
-
Dejaeger, E.1
Pelemans, W.2
Ponette, E.3
Joosten, E.4
-
8
-
-
3242665901
-
Laryngo-upper esophageal sphincter contractile reflex in humans deteriorates with age
-
Kawamura O, Easterling C, Aslam M, Rittmann T, Hofmann C, Shaker R. Laryngo-upper esophageal sphincter contractile reflex in humans deteriorates with age. Gastroenterology 2004; 127: 57-64.
-
(2004)
Gastroenterology
, vol.127
, pp. 57-64
-
-
Kawamura, O.1
Easterling, C.2
Aslam, M.3
Rittmann, T.4
Hofmann, C.5
Shaker, R.6
-
9
-
-
0028904404
-
Pharyngeal sensation and gag reflex in healthy subjects
-
Davies AE, Kidd D, Stone SP, MacMahon J. Pharyngeal sensation and gag reflex in healthy subjects. Lancet 1995; 345: 487-8.
-
(1995)
Lancet
, vol.345
, pp. 487-488
-
-
Davies, A.E.1
Kidd, D.2
Stone, S.P.3
MacMahon, J.4
-
10
-
-
0025647039
-
Anorexia in older patients: its meaning and management
-
Morley JE. Anorexia in older patients: its meaning and management. Geriatrics 1990; 45: 65-6.
-
(1990)
Geriatrics
, vol.45
, pp. 65-66
-
-
Morley, J.E.1
-
11
-
-
34247534646
-
Basic mechanisms of the aging gastrointestinal tract
-
Salles N. Basic mechanisms of the aging gastrointestinal tract. Dig Dis 2007; 25: 112-7.
-
(2007)
Dig Dis
, vol.25
, pp. 112-117
-
-
Salles, N.1
-
12
-
-
0036039387
-
Aging and intestinal motility: a review of factors that affect intestinal motility in the aged
-
O'Mahony D, O'Leary P, Quigley EM. Aging and intestinal motility: a review of factors that affect intestinal motility in the aged. Drugs Aging 2002; 19: 515-27.
-
(2002)
Drugs Aging
, vol.19
, pp. 515-527
-
-
O'Mahony, D.1
O'Leary, P.2
Quigley, E.M.3
-
13
-
-
55949114689
-
Deterioration of muscle function in the human esophagus with age
-
Gregersen H, Pedersen J, Drewes AM. Deterioration of muscle function in the human esophagus with age. Dig Dis Sci 2008; 53: 3065-70.
-
(2008)
Dig Dis Sci
, vol.53
, pp. 3065-3070
-
-
Gregersen, H.1
Pedersen, J.2
Drewes, A.M.3
-
14
-
-
58549117491
-
Age and gender affect likely manometric diagnosis: audit of a tertiary referral hospital clinical esophageal manometry service
-
Andrews JM, Heddle R, Hebbard GS, Checklin H, Besanko L, Fraser RJ. Age and gender affect likely manometric diagnosis: audit of a tertiary referral hospital clinical esophageal manometry service. J Gastroenterol Hepatol 2009; 24: 125-8.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. 125-128
-
-
Andrews, J.M.1
Heddle, R.2
Hebbard, G.S.3
Checklin, H.4
Besanko, L.5
Fraser, R.J.6
-
15
-
-
36549011666
-
Effects of age on the gastroesophageal junction, esophageal motility, and reflux disease
-
Lee J, Anggiansah A, Anggiansah R, Young A, Wong T, Fox M. Effects of age on the gastroesophageal junction, esophageal motility, and reflux disease. Clin Gastroenterol Hepatol 2007; 5: 1392-8.
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 1392-1398
-
-
Lee, J.1
Anggiansah, A.2
Anggiansah, R.3
Young, A.4
Wong, T.5
Fox, M.6
-
16
-
-
1542359600
-
Effects of ageing on gastrointestinal motor function
-
Madsen JL, Graff J. Effects of ageing on gastrointestinal motor function. Age Ageing 2004; 33: 154-9.
-
(2004)
Age Ageing
, vol.33
, pp. 154-159
-
-
Madsen, J.L.1
Graff, J.2
-
17
-
-
79955888565
-
The effects of age on regional and whole gut transit times in healthy adults
-
Abstract.
-
Saad RJ, Semler JR, Wilding GE, Chey WD. The effects of age on regional and whole gut transit times in healthy adults. Gastroenterol 2010; 138: S-127 (Abstract).
-
(2010)
Gastroenterol
, vol.138
-
-
Saad, R.J.1
Semler, J.R.2
Wilding, G.E.3
Chey, W.D.4
-
18
-
-
0036976301
-
Evaluation of gastric motor activity in the elderly by electrogastrography and the (13)C-acetate breath test
-
Shimamoto C, Hirata I, Hiraike Y, Takeuchi N, Nomura T, Katsu K. Evaluation of gastric motor activity in the elderly by electrogastrography and the (13)C-acetate breath test. Gerontology 2002; 48: 381-6.
-
(2002)
Gerontology
, vol.48
, pp. 381-386
-
-
Shimamoto, C.1
Hirata, I.2
Hiraike, Y.3
Takeuchi, N.4
Nomura, T.5
Katsu, K.6
-
19
-
-
0036889708
-
Aging and neural control of the GI tract: IV. Clinical and physiological aspects of gastrointestinal motility and aging
-
Orr WC, Chen CL. Aging and neural control of the GI tract: IV. Clinical and physiological aspects of gastrointestinal motility and aging. Am J Physiol Gastrointest Liver Physiol 2002; 283: G1226-31.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
-
-
Orr, W.C.1
Chen, C.L.2
-
20
-
-
0035043452
-
Gastrointestinal mean transit times in young and middle-aged healthy subjects
-
Graff J, Brinch K, Madsen JL. Gastrointestinal mean transit times in young and middle-aged healthy subjects. Clin Physiol 2001; 21: 253-9.
-
(2001)
Clin Physiol
, vol.21
, pp. 253-259
-
-
Graff, J.1
Brinch, K.2
Madsen, J.L.3
-
22
-
-
33751302773
-
Effect of aging on anorectal and pelvic floor functions in females
-
Fox JC, Fletcher JG, Zinsmeister AR, Seide B, Riederer SJ, Bharucha AE. Effect of aging on anorectal and pelvic floor functions in females. Dis Colon Rectum 2006; 49: 1726-35.
-
(2006)
Dis Colon Rectum
, vol.49
, pp. 1726-1735
-
-
Fox, J.C.1
Fletcher, J.G.2
Zinsmeister, A.R.3
Seide, B.4
Riederer, S.J.5
Bharucha, A.E.6
-
23
-
-
0030929886
-
Neocortical neuron numbers in human: effect of sex and age
-
Pakkenburg B, Gunderson HJ. Neocortical neuron numbers in human: effect of sex and age. J Comp Neurol 1997; 384: 312-20.
-
(1997)
J Comp Neurol
, vol.384
, pp. 312-320
-
-
Pakkenburg, B.1
Gunderson, H.J.2
-
24
-
-
0029910181
-
Neuropeptide and neurotrophin receptor mRNAs in pain sensory neurons of aged rats
-
Bergman E, Johnson H, Zhang X et al. Neuropeptide and neurotrophin receptor mRNAs in pain sensory neurons of aged rats. J Comp Neurol 1996; 11: 303-19.
-
(1996)
J Comp Neurol
, vol.11
, pp. 303-319
-
-
Bergman, E.1
Johnson, H.2
Zhang, X.3
-
25
-
-
0021704143
-
Effects of age on dopamine and serotonin receptors measured by positron tomography in the living brain
-
Wong DF, Wagner HN, Dannals RF et al. Effects of age on dopamine and serotonin receptors measured by positron tomography in the living brain. Science 1984; 226: 1393-6.
-
(1984)
Science
, vol.226
, pp. 1393-1396
-
-
Wong, D.F.1
Wagner, H.N.2
Dannals, R.F.3
-
26
-
-
0038488561
-
Aging of the myenteric plexus: neuronal loss is specific to cholinergic neurons
-
Phillips RJ, Kieffer EJ, Powley TL. Aging of the myenteric plexus: neuronal loss is specific to cholinergic neurons. Auton Neurosci 2003; 106: 69-83.
-
(2003)
Auton Neurosci
, vol.106
, pp. 69-83
-
-
Phillips, R.J.1
Kieffer, E.J.2
Powley, T.L.3
-
27
-
-
70350573008
-
Age-related changes in functional NANC innervation with VIP and substance P in the jejunum of Lewis rats
-
Kasparek MS, Fatima J, Iqbal CW, Duenes JA, Sarr MG. Age-related changes in functional NANC innervation with VIP and substance P in the jejunum of Lewis rats. Auton Neurosci 2009; 151: 127-34.
-
(2009)
Auton Neurosci
, vol.151
, pp. 127-134
-
-
Kasparek, M.S.1
Fatima, J.2
Iqbal, C.W.3
Duenes, J.A.4
Sarr, M.G.5
-
28
-
-
70049101651
-
Fall in density, but not number of myenteric neurons and circular muscle nerve fibres in guinea-pig colon with ageing
-
Peck CJ, Samsuria SD, Harrington AM, King SK, Hutson JM, Southwell BR. Fall in density, but not number of myenteric neurons and circular muscle nerve fibres in guinea-pig colon with ageing. Neurogastroenterol Motil 2009; 21: 1075-90.
-
(2009)
Neurogastroenterol Motil
, vol.21
, pp. 1075-1090
-
-
Peck, C.J.1
Samsuria, S.D.2
Harrington, A.M.3
King, S.K.4
Hutson, J.M.5
Southwell, B.R.6
-
29
-
-
3543127161
-
Age-related changes in the morphology of the myenteric plexus of the human colon
-
Hanani M, Fellig Y, Udassin R, Freund HR. Age-related changes in the morphology of the myenteric plexus of the human colon. Auton Neurosci 2004; 113: 71-8.
-
(2004)
Auton Neurosci
, vol.113
, pp. 71-78
-
-
Hanani, M.1
Fellig, Y.2
Udassin, R.3
Freund, H.R.4
-
31
-
-
0034517285
-
Influence of age on periphera nerve function and regeneration
-
Verdu E, Ceballos D, Vilches JJ et al. Influence of age on periphera nerve function and regeneration. J Peripher Nerv Syst 2000; 5: 191-208.
-
(2000)
J Peripher Nerv Syst
, vol.5
, pp. 191-208
-
-
Verdu, E.1
Ceballos, D.2
Vilches, J.J.3
-
32
-
-
0035859865
-
Frequency of bowel movement and the future risk of Parkinson's disease
-
Abbott RD, Petrovitch H, White LR et al. Frequency of bowel movement and the future risk of Parkinson's disease. Neurology 2001; 57: 456-62.
-
(2001)
Neurology
, vol.57
, pp. 456-462
-
-
Abbott, R.D.1
Petrovitch, H.2
White, L.R.3
-
34
-
-
77952478217
-
Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutation precede central nervous system changes
-
Kuo YM, Li Z, Jiao Y et al. Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutation precede central nervous system changes. Hum Mol Genet 2010; 19: 1633-50.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 1633-1650
-
-
Kuo, Y.M.1
Li, Z.2
Jiao, Y.3
-
35
-
-
34548230441
-
Loss of enteric dopaminergic neurons and associated changes in colonic motility in an MPTP mouse model of Parkinson's disease
-
Anderson G, Noorian AR, Taylor G et al. Loss of enteric dopaminergic neurons and associated changes in colonic motility in an MPTP mouse model of Parkinson's disease. Exp Neurol 2007; 207: 4-12.
-
(2007)
Exp Neurol
, vol.207
, pp. 4-12
-
-
Anderson, G.1
Noorian, A.R.2
Taylor, G.3
-
36
-
-
67349122370
-
Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease
-
Green JG, Noorian AR, Srinivasa S. Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease. Exp Neurol 2009; 218: 154-61.
-
(2009)
Exp Neurol
, vol.218
, pp. 154-161
-
-
Green, J.G.1
Noorian, A.R.2
Srinivasa, S.3
-
37
-
-
43249106066
-
Abnormal colonic motility in mice overexpressing human wild-type s-synuclein
-
Wang L, Fleming SM, Chesselet M-F, Tache Y. Abnormal colonic motility in mice overexpressing human wild-type s-synuclein. Neuroreport 2008; 19: 873-6.
-
(2008)
Neuroreport
, vol.19
, pp. 873-876
-
-
Wang, L.1
Fleming, S.M.2
Chesselet, M.-F.3
Tache, Y.4
-
38
-
-
70349743692
-
Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat
-
Phillips RJ, Walter GC, Ringer BE, Higgs KM, Powley TL. Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat. Exp Neurol 2009; 220: 109-19.
-
(2009)
Exp Neurol
, vol.220
, pp. 109-119
-
-
Phillips, R.J.1
Walter, G.C.2
Ringer, B.E.3
Higgs, K.M.4
Powley, T.L.5
-
39
-
-
41149110768
-
Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminal: autonomic pathway implicated in Parkinson's disease?
-
Phillips RJ, Walter GC, Wilder SL et al. Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminal: autonomic pathway implicated in Parkinson's disease? Neurosci 2008; 153: 733-50.
-
(2008)
Neurosci
, vol.153
, pp. 733-750
-
-
Phillips, R.J.1
Walter, G.C.2
Wilder, S.L.3
-
40
-
-
34247382481
-
Age-related neuronal loss in the submucosal plexus of the colon of Fischer 344 rats
-
Phillips RJ, Pairitz JC, Powley TL. Age-related neuronal loss in the submucosal plexus of the colon of Fischer 344 rats. Neurobiol Aging 2007; 28: 1124-37.
-
(2007)
Neurobiol Aging
, vol.28
, pp. 1124-1137
-
-
Phillips, R.J.1
Pairitz, J.C.2
Powley, T.L.3
-
41
-
-
0026567833
-
Prevalence of gastrointestinal symptoms in the elderly: a population-based study
-
Talley NJ, O'Keefe E, Zinsmeister AR, Melton LJ. Prevalence of gastrointestinal symptoms in the elderly: a population-based study. Gastroenterol 1992; 102: 895-901.
-
(1992)
Gastroenterol
, vol.102
, pp. 895-901
-
-
Talley, N.J.1
O'Keefe, E.2
Zinsmeister, A.R.3
Melton, L.J.4
-
42
-
-
0031014806
-
Evidence for diminished visceral pain with aging: studies using graded intraesophageal balloon distension
-
Lasch H, Castel DO, Castel JA. Evidence for diminished visceral pain with aging: studies using graded intraesophageal balloon distension. Am J Physiol 1997; 272: G1-3.
-
(1997)
Am J Physiol
, vol.272
-
-
Lasch, H.1
Castel, D.O.2
Castel, J.A.3
-
43
-
-
0033002141
-
Influence of age on rectal tone and sensitivity to distension in healthy subjects
-
Lagier E, Delvaux M, Vellas B et al. Influence of age on rectal tone and sensitivity to distension in healthy subjects. Neurogastroenterol Motil 1999; 11: 101-7.
-
(1999)
Neurogastroenterol Motil
, vol.11
, pp. 101-107
-
-
Lagier, E.1
Delvaux, M.2
Vellas, B.3
-
44
-
-
0029671403
-
The effect of age on A delta and C-fiber pain perception
-
Chakour MC, Gibsni SJ, Bradbeer M, Helme RD. The effect of age on A delta and C-fiber pain perception. Pain 1996; 64: 143-52.
-
(1996)
Pain
, vol.64
, pp. 143-152
-
-
Chakour, M.C.1
Gibsni, S.J.2
Bradbeer, M.3
Helme, R.D.4
-
45
-
-
50849113418
-
Age-related differences in nociceptive behavior between SAMP6 and SAMR1 strains
-
Niimi K, Takahashi E, Itakur C. Age-related differences in nociceptive behavior between SAMP6 and SAMR1 strains. Neurosci Lett 2008; 444: 60-3.
-
(2008)
Neurosci Lett
, vol.444
, pp. 60-63
-
-
Niimi, K.1
Takahashi, E.2
Itakur, C.3
-
46
-
-
0345868387
-
Underlying mechanisms of impaired visceral pain perception in older people
-
Moore AR, Clinch D. Underlying mechanisms of impaired visceral pain perception in older people. J Am Geriatr Soc 2004; 52: 132-6.
-
(2004)
J Am Geriatr Soc
, vol.52
, pp. 132-136
-
-
Moore, A.R.1
Clinch, D.2
-
47
-
-
78650139613
-
Changes in interstitial cells of cajal with age in the human stomach and colon
-
Gomez-Pinilla PJ, Gibbons SJ, Sarr MG et al. Changes in interstitial cells of cajal with age in the human stomach and colon. Neurogastroenterol Motil 2011; 23: 36-44.
-
(2011)
Neurogastroenterol Motil
, vol.23
, pp. 36-44
-
-
Gomez-Pinilla, P.J.1
Gibbons, S.J.2
Sarr, M.G.3
-
48
-
-
11244326684
-
Loss of glia and neurons in the myenteric plexus of the aged Fischer 344 rat
-
Phillips RJ, Kieffer EJ, Powley TL. Loss of glia and neurons in the myenteric plexus of the aged Fischer 344 rat. Anat Embryol (Berl) 2004; 209: 19-30.
-
(2004)
Anat Embryol (Berl)
, vol.209
, pp. 19-30
-
-
Phillips, R.J.1
Kieffer, E.J.2
Powley, T.L.3
-
49
-
-
0037104668
-
Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsivements
-
Kruger GM, Mosher JT, Bixby S, Joseph N, Iwashita T, Morrison SJ. Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsivements. Neuron 2002; 35: 657-69.
-
(2002)
Neuron
, vol.35
, pp. 657-669
-
-
Kruger, G.M.1
Mosher, J.T.2
Bixby, S.3
Joseph, N.4
Iwashita, T.5
Morrison, S.J.6
-
50
-
-
68549123001
-
5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice
-
Liu MT, Kuan YH, Wang J, Hen R, Gershon MD. 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. J Neurosci 2009; 29: 9683-99.
-
(2009)
J Neurosci
, vol.29
, pp. 9683-9699
-
-
Liu, M.T.1
Kuan, Y.H.2
Wang, J.3
Hen, R.4
Gershon, M.D.5
-
51
-
-
0029898110
-
Influence of age on cholinergic and inhibitory nonadrenergic noncholinergic responses in the rat ileum
-
Smits GJ, Lefebvre RA. Influence of age on cholinergic and inhibitory nonadrenergic noncholinergic responses in the rat ileum. Eur J Pharmacol 1996; 303: 79-86.
-
(1996)
Eur J Pharmacol
, vol.303
, pp. 79-86
-
-
Smits, G.J.1
Lefebvre, R.A.2
-
53
-
-
79955892015
-
Age-related decline in myosin phosphatase-mediated maintenance of myosin light chain phosphorylation can be restored by phosphorylated Hsp27 in colonic smooth muscle [Abstract]
-
Somara S, Hecker L, Bitar KN. Age-related decline in myosin phosphatase-mediated maintenance of myosin light chain phosphorylation can be restored by phosphorylated Hsp27 in colonic smooth muscle [Abstract]. Neurogastroenterol Motil 2005; 17: 1.
-
(2005)
Neurogastroenterol Motil
, vol.17
, Issue.1
-
-
Somara, S.1
Hecker, L.2
Bitar, K.N.3
-
55
-
-
0037229022
-
Aging and neural control of the GI tract: V. Aging and gastrointestinal smooth muscle: from signal transduction to contractile proteins
-
Bitar KN. Aging and neural control of the GI tract: V. Aging and gastrointestinal smooth muscle: from signal transduction to contractile proteins. Am J Physiol Gastrointest Liver Physiol 2003; 284: G1-7.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Bitar, K.N.1
-
56
-
-
33644850056
-
Progressive disruption of cellular protein folding in models of polyglutamine diseases
-
Gidalevitz T, Ben-Zvi A, Ho KH, Brignull HR, Morimoto RI. Progressive disruption of cellular protein folding in models of polyglutamine diseases. Science 2006; 311: 1471-4.
-
(2006)
Science
, vol.311
, pp. 1471-1474
-
-
Gidalevitz, T.1
Ben-Zvi, A.2
Ho, K.H.3
Brignull, H.R.4
Morimoto, R.I.5
-
57
-
-
6344286028
-
Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila
-
Morrow G, Battistini S, Zhang P, Tanguay RM. Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila. J Biol Chem 2004; 279: 43382-5.
-
(2004)
J Biol Chem
, vol.279
, pp. 43382-43385
-
-
Morrow, G.1
Battistini, S.2
Zhang, P.3
Tanguay, R.M.4
-
58
-
-
2442649342
-
Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress
-
Morrow G, Samson M, Michaud S, Tanguay RM. Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. FASEB J 2004; 18: 598-9.
-
(2004)
FASEB J
, vol.18
, pp. 598-599
-
-
Morrow, G.1
Samson, M.2
Michaud, S.3
Tanguay, R.M.4
-
59
-
-
77950470205
-
Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells
-
Wadhwa R, Ryu J, Gao R et al. Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells. J Biol Chem 2010; 285: 3833-9.
-
(2010)
J Biol Chem
, vol.285
, pp. 3833-3839
-
-
Wadhwa, R.1
Ryu, J.2
Gao, R.3
-
60
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu AL, Murphy CT, Kenyon C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 2003; 300: 1142-5.
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
61
-
-
0033951649
-
The insulin-like growth factor axis: a review of atherosclerosis and restenosis
-
Bayes-Genis A, Conover CA, Schwartz RS. The insulin-like growth factor axis: a review of atherosclerosis and restenosis. Circ Res 2000; 86: 125-30.
-
(2000)
Circ Res
, vol.86
, pp. 125-130
-
-
Bayes-Genis, A.1
Conover, C.A.2
Schwartz, R.S.3
-
62
-
-
78751704345
-
Growth hormone, insulin and aging: the benefits of endocrine defects
-
Bartke A. Growth hormone, insulin and aging: the benefits of endocrine defects. Exp Gerontol 2011; 46: 108-11.
-
(2011)
Exp Gerontol
, vol.46
, pp. 108-111
-
-
Bartke, A.1
-
63
-
-
0024520374
-
Vasoactive effects of growth factors
-
Berk BC, Alexander RW. Vasoactive effects of growth factors. Biochem Pharmacol 1989; 38: 219-25.
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 219-225
-
-
Berk, B.C.1
Alexander, R.W.2
-
64
-
-
0035956429
-
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF
-
Taya S, Inagaki N, Sengiku H et al. Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF. J Cell Biol 2001; 155: 809-20.
-
(2001)
J Cell Biol
, vol.155
, pp. 809-820
-
-
Taya, S.1
Inagaki, N.2
Sengiku, H.3
-
65
-
-
0035150402
-
Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
-
Fukata Y, Amano M, Kaibuchi K. Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol Sci 2001; 22: 32-9.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 32-39
-
-
Fukata, Y.1
Amano, M.2
Kaibuchi, K.3
-
66
-
-
2942514584
-
Growth factor-induced contraction of human bronchial smooth muscle is Rho-kinase-dependent
-
Gosens R, Schaafsma D, Grootte-Bromhaar M et al. Growth factor-induced contraction of human bronchial smooth muscle is Rho-kinase-dependent. Eur J Pharmacol 2004; 494: 73-6.
-
(2004)
Eur J Pharmacol
, vol.494
, pp. 73-76
-
-
Gosens, R.1
Schaafsma, D.2
Grootte-Bromhaar, M.3
-
67
-
-
0346096592
-
Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype
-
Gosens R, Schaafsma D, Meurs H, Zaagsma J, Nelemans SA. Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype. Eur J Pharmacol 2004; 483: 71-8.
-
(2004)
Eur J Pharmacol
, vol.483
, pp. 71-78
-
-
Gosens, R.1
Schaafsma, D.2
Meurs, H.3
Zaagsma, J.4
Nelemans, S.A.5
-
68
-
-
78549237781
-
Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: defective bricks build a defective house
-
Rai P. Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: defective bricks build a defective house. Mutat Res 2010; 703: 71-81.
-
(2010)
Mutat Res
, vol.703
, pp. 71-81
-
-
Rai, P.1
-
71
-
-
78049353347
-
Regulation of protein turnover by longevity pathways
-
Vellai T, Takacs-Vellai K. Regulation of protein turnover by longevity pathways. Adv Exp Med Biol 2010; 694: 69-80.
-
(2010)
Adv Exp Med Biol
, vol.694
, pp. 69-80
-
-
Vellai, T.1
Takacs-Vellai, K.2
-
72
-
-
77956189388
-
Signaling pathways in mitochondrial dysfunction and aging
-
Mammucari C, Rizzuto R. Signaling pathways in mitochondrial dysfunction and aging. Mech Ageing Dev 2010; 131: 536-43.
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 536-543
-
-
Mammucari, C.1
Rizzuto, R.2
-
73
-
-
57649234905
-
Autophagy genes and ageing
-
Vellai T. Autophagy genes and ageing. Cell Death Differ 2009; 16: 94-102.
-
(2009)
Cell Death Differ
, vol.16
, pp. 94-102
-
-
Vellai, T.1
-
74
-
-
38949099761
-
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
-
Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD. Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 2008; 4: 176-84.
-
(2008)
Autophagy
, vol.4
, pp. 176-184
-
-
Simonsen, A.1
Cumming, R.C.2
Brech, A.3
Isakson, P.4
Schubert, D.R.5
Finley, K.D.6
-
76
-
-
67349273985
-
SIRT1: regulation of longevity via autophagy
-
Salminen A, Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell Signal 2009; 21: 1356-60.
-
(2009)
Cell Signal
, vol.21
, pp. 1356-1360
-
-
Salminen, A.1
Kaarniranta, K.2
-
77
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460: 392-5.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
-
78
-
-
70349669095
-
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
-
Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science 2009; 326: 140-4.
-
(2009)
Science
, vol.326
, pp. 140-144
-
-
Selman, C.1
Tullet, J.M.2
Wieser, D.3
Irvine, E.4
Lingard, S.J.5
-
79
-
-
77956305343
-
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease
-
Spilman P, Podlutskaya N, Hart MJ et al. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. PLoS One 2010; 5: 9979.
-
(2010)
PLoS One
, vol.5
, pp. 9979
-
-
Spilman, P.1
Podlutskaya, N.2
Hart, M.J.3
-
80
-
-
78649840561
-
NAD: a master regulator of transcription
-
Ghosh S, George S, Roy U, Ramachandran D, Kolthur-Seetharam U. NAD: a master regulator of transcription. Biochim Biophys Acta 2010; 1799: 681-93.
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 681-693
-
-
Ghosh, S.1
George, S.2
Roy, U.3
Ramachandran, D.4
Kolthur-Seetharam, U.5
-
81
-
-
77951176737
-
Extending healthy life span - from yeast to humans
-
Fontana L, Partridge L, Longo VD. Extending healthy life span - from yeast to humans. Science 2010; 328: 321-6.
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
82
-
-
70350438130
-
Morphometric and quantitative study of the myenteric neurons of the stomach of malnourished aging rats
-
de Sousa FC, Neto MH. Morphometric and quantitative study of the myenteric neurons of the stomach of malnourished aging rats. Nutr Neurosci 2009; 12: 167-74.
-
(2009)
Nutr Neurosci
, vol.12
, pp. 167-174
-
-
de Sousa, F.C.1
Neto, M.H.2
-
83
-
-
77955747346
-
With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging
-
Kapahi P, Chen D, Rogers AN et al. With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab 2010; 11: 453-65.
-
(2010)
Cell Metab
, vol.11
, pp. 453-465
-
-
Kapahi, P.1
Chen, D.2
Rogers, A.N.3
-
84
-
-
77953577017
-
mTOR's role in ageing: protein synthesis or autophagy?
-
Hands SL, Proud CG, Wyttenbach A. mTOR's role in ageing: protein synthesis or autophagy? Aging 2009; 1: 586-97.
-
(2009)
Aging
, vol.1
, pp. 586-597
-
-
Hands, S.L.1
Proud, C.G.2
Wyttenbach, A.3
-
85
-
-
77049084743
-
Omega-3 polyunsaturated fatty acids increase the neurite outgrowth of rat sensory neurons throughout development and in aged animals
-
Robson LG, Dyall S, Sidloff D, Michael-Titus AT. Omega-3 polyunsaturated fatty acids increase the neurite outgrowth of rat sensory neurons throughout development and in aged animals. Neurobiol Aging 2010; 31: 678-87.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 678-687
-
-
Robson, L.G.1
Dyall, S.2
Sidloff, D.3
Michael-Titus, A.T.4
-
86
-
-
20044394168
-
Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions
-
Yamashita T, Wu YP, Sandhoff R et al. Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions. Proc Natl Acad Sci USA 2005; 102: 2725-30.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2725-2730
-
-
Yamashita, T.1
Wu, Y.P.2
Sandhoff, R.3
-
87
-
-
71049144353
-
Sialic acid feeding aged rats rejuvenates stimulated salivation and subpopulations of colon enteric chemotypes
-
Sprenger N, Julita M, Donnicola D, Jann A. Sialic acid feeding aged rats rejuvenates stimulated salivation and subpopulations of colon enteric chemotypes. Glycobiology 2009; 19: 1492-502.
-
(2009)
Glycobiology
, vol.19
, pp. 1492-1502
-
-
Sprenger, N.1
Julita, M.2
Donnicola, D.3
Jann, A.4
-
88
-
-
77952549055
-
A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis
-
Imai S. A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis. Pharmacol Res 2010; 62: 42-7.
-
(2010)
Pharmacol Res
, vol.62
, pp. 42-47
-
-
Imai, S.1
|