메뉴 건너뛰기




Volumn 46, Issue 2-3, 2011, Pages 108-111

Growth hormone, insulin and aging: The benefits of endocrine defects

Author keywords

Cancer; Dwarf mice; Insulin like growth factor 1 (IGF 1); Longevity

Indexed keywords

GROWTH HORMONE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PROLACTIN; SOMATOMEDIN C; THYROTROPIN;

EID: 78751704345     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2010.08.020     Document Type: Article
Times cited : (42)

References (38)
  • 2
    • 12344335482 scopus 로고    scopus 로고
    • Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor 1/insulin signaling and caloric restriction
    • Al-Regaiey K.A., Masternak M.M., Bonkowski M., Sun L., Bartke A. Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor 1/insulin signaling and caloric restriction. Endocrinology 2005, 146:851-860.
    • (2005) Endocrinology , vol.146 , pp. 851-860
    • Al-Regaiey, K.A.1    Masternak, M.M.2    Bonkowski, M.3    Sun, L.4    Bartke, A.5
  • 4
    • 84882819253 scopus 로고    scopus 로고
    • Life extension in the dwarf mouse
    • Elsevier Academic Press, P.M. Conn (Ed.)
    • Bartke A. Life extension in the dwarf mouse. Handbook of models for the study of human aging 2006, 403-414. Elsevier Academic Press. P.M. Conn (Ed.).
    • (2006) Handbook of models for the study of human aging , pp. 403-414
    • Bartke, A.1
  • 6
    • 33646731782 scopus 로고    scopus 로고
    • Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction
    • Bonkowski M.S., Rocha J.S., Masternak M.M., Al Regaiey K.A., Bartke A. Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc. Natl Acad. Sci. 2006, 103:7901-7905.
    • (2006) Proc. Natl Acad. Sci. , vol.103 , pp. 7901-7905
    • Bonkowski, M.S.1    Rocha, J.S.2    Masternak, M.M.3    Al Regaiey, K.A.4    Bartke, A.5
  • 9
    • 33746896909 scopus 로고    scopus 로고
    • Longevity in mice: is stress resistance a common factor?
    • Brown-Borg H.M. Longevity in mice: is stress resistance a common factor?. Age (Dordr) 2006, 28:145-162.
    • (2006) Age (Dordr) , vol.28 , pp. 145-162
    • Brown-Borg, H.M.1
  • 10
    • 12344322861 scopus 로고    scopus 로고
    • Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice
    • Brown-Borg H.M., Rakoczy S.G., Uthus E.O. Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice. Mech. Ageing Dev. 2005, 126:389-398.
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 389-398
    • Brown-Borg, H.M.1    Rakoczy, S.G.2    Uthus, E.O.3
  • 15
    • 0036751228 scopus 로고    scopus 로고
    • Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice
    • Hauck S.J., Aaron J.M., Wright C., Kopchick J.J., Bartke A. Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm. Metab. Res. 2002, 481-486.
    • (2002) Horm. Metab. Res. , pp. 481-486
    • Hauck, S.J.1    Aaron, J.M.2    Wright, C.3    Kopchick, J.J.4    Bartke, A.5
  • 16
    • 0032864653 scopus 로고    scopus 로고
    • Low body temperature in long-lived Ames dwarf mice at rest and during stress
    • Hunter W.S., Croson W.B., Bartke A., Gentry M.V., Meliska C.J. Low body temperature in long-lived Ames dwarf mice at rest and during stress. Physiol. Behav. 1999, 67:433-437.
    • (1999) Physiol. Behav. , vol.67 , pp. 433-437
    • Hunter, W.S.1    Croson, W.B.2    Bartke, A.3    Gentry, M.V.4    Meliska, C.J.5
  • 17
    • 0345237923 scopus 로고    scopus 로고
    • Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: correlation to extended longevity
    • Ikeno Y., Bronson R.T., Hubbard G.B., Lee S., Bartke A. Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: correlation to extended longevity. J. Gerontol. A Biol. Sci. Med. Sci. 2003, 58:291-296.
    • (2003) J. Gerontol. A Biol. Sci. Med. Sci. , vol.58 , pp. 291-296
    • Ikeno, Y.1    Bronson, R.T.2    Hubbard, G.B.3    Lee, S.4    Bartke, A.5
  • 19
    • 0035051811 scopus 로고    scopus 로고
    • Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice
    • Kinney B.A., Coschigano K.T., Kopchick J.J., Bartke A. Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiol. Behav. 2001, 72:653-660.
    • (2001) Physiol. Behav. , vol.72 , pp. 653-660
    • Kinney, B.A.1    Coschigano, K.T.2    Kopchick, J.J.3    Bartke, A.4
  • 20
    • 78751701075 scopus 로고    scopus 로고
    • personal communication.
    • Longo, V. personal communication.
    • Longo, V.1
  • 24
    • 0013056730 scopus 로고    scopus 로고
    • Big mice die young: Early life body weight predicts longevity in genetically heterogeneous mice
    • Miller R.A., Harper J.M., Galecki A., Burke D.T. Big mice die young: Early life body weight predicts longevity in genetically heterogeneous mice. Aging Cell 2002, 1:22-29.
    • (2002) Aging Cell , vol.1 , pp. 22-29
    • Miller, R.A.1    Harper, J.M.2    Galecki, A.3    Burke, D.T.4
  • 26
    • 0036358167 scopus 로고    scopus 로고
    • Growth negatively impacts the life span of mammals
    • Rollo C.D. Growth negatively impacts the life span of mammals. Evol. Dev. 2002, 4:55-61.
    • (2002) Evol. Dev. , vol.4 , pp. 55-61
    • Rollo, C.D.1
  • 29
    • 40849102760 scopus 로고    scopus 로고
    • Hippocampus of Ames dwarf mice is resistant to beta-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels
    • Schrag M., Sharma S., Brown-Borg H., Ghribi O. Hippocampus of Ames dwarf mice is resistant to beta-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels. Hippocampus 2008, 18:239-244.
    • (2008) Hippocampus , vol.18 , pp. 239-244
    • Schrag, M.1    Sharma, S.2    Brown-Borg, H.3    Ghribi, O.4
  • 31
    • 18244379033 scopus 로고    scopus 로고
    • Evidence for down-regulation of phosphoinositide 3-kinase/akt/mammalian target of rapamycin (pi3k/akt/mtor)-dependent translation regulatory signaling pathways in Ames dwarf mice
    • Sharp Z.D., Bartke A. Evidence for down-regulation of phosphoinositide 3-kinase/akt/mammalian target of rapamycin (pi3k/akt/mtor)-dependent translation regulatory signaling pathways in Ames dwarf mice. J. Gerontol. A Biol. Sci. Med. Sci. 2005, 60:293-300.
    • (2005) J. Gerontol. A Biol. Sci. Med. Sci. , vol.60 , pp. 293-300
    • Sharp, Z.D.1    Bartke, A.2
  • 32
    • 33847198926 scopus 로고    scopus 로고
    • Patients with congenital deficiency of IGF-I seem protected from the development of malignancies: a preliminary report
    • Shevah O., Laron Z. Patients with congenital deficiency of IGF-I seem protected from the development of malignancies: a preliminary report. Growth Horm. IGF Res. 2007, 17:54-57.
    • (2007) Growth Horm. IGF Res. , vol.17 , pp. 54-57
    • Shevah, O.1    Laron, Z.2
  • 33
    • 13844277026 scopus 로고    scopus 로고
    • Local expression of GH and IGF-1 in the hippocampus of gh-deficient long-lived mice
    • Sun L.Y., Al-Regaiey K., Masternak M.M., Wang J., Bartke A. Local expression of GH and IGF-1 in the hippocampus of gh-deficient long-lived mice. Neurobiol. Aging 2005, 26:929-937.
    • (2005) Neurobiol. Aging , vol.26 , pp. 929-937
    • Sun, L.Y.1    Al-Regaiey, K.2    Masternak, M.M.3    Wang, J.4    Bartke, A.5
  • 34
    • 70449523451 scopus 로고    scopus 로고
    • Fibroblasts from long-lived mutant mice show diminished erk1/2 phosphorylation but exaggerated induction of immediate early genes
    • Sun L.Y., Steinbaugh M.J., Masternak M.M., Bartke A., Miller R.A. Fibroblasts from long-lived mutant mice show diminished erk1/2 phosphorylation but exaggerated induction of immediate early genes. Free Radic. Biol. Med. 2009, 47:1753-1761.
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 1753-1761
    • Sun, L.Y.1    Steinbaugh, M.J.2    Masternak, M.M.3    Bartke, A.4    Miller, R.A.5
  • 36
    • 55849101681 scopus 로고    scopus 로고
    • Fat metabolism links germline stem cells and longevity in C. elegans
    • Wang M.C., O'Rourke E.J., Ruvkun G. Fat metabolism links germline stem cells and longevity in C. elegans. Science 2008, 322:957-960.
    • (2008) Science , vol.322 , pp. 957-960
    • Wang, M.C.1    O'Rourke, E.J.2    Ruvkun, G.3
  • 37
    • 64849086653 scopus 로고    scopus 로고
    • Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice
    • Westbrook R., Bonkowski M.S., Strader A.D., Bartke A. Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice. J. Gerontol. A Biol. Sci. Med. Sci. 2009, 64A:443-451.
    • (2009) J. Gerontol. A Biol. Sci. Med. Sci. , vol.64 A , pp. 443-451
    • Westbrook, R.1    Bonkowski, M.S.2    Strader, A.D.3    Bartke, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.