-
1
-
-
43049180299
-
Ageing and the regulation of protein syn thesis: A balancing act?
-
Tavernarakis N. Ageing and the regulation of protein synthesis: a balancing act? Trends Cell Biol 2008; 18:228-35.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 228-235
-
-
Tavernarakis, N.1
-
2
-
-
33847199335
-
EIF4E function in somatic cells modulates ageing in Caenorhabditis elegans
-
Syntichaki P, Troulinaki K, Tavernarakis N. eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature 2007; 445:922-6.
-
(2007)
Nature
, vol.445
, pp. 922-926
-
-
Syntichaki, P.1
Troulinaki, K.2
Tavernarakis, N.3
-
3
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
DOI 10.1111/j.1474-9726.2006.00267.x
-
Hansen M, Taubert S, Crawford D et al. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 2007; 6:95-110. (Pubitemid 46140143)
-
(2007)
Aging Cell
, vol.6
, Issue.1
, pp. 95-110
-
-
Hansen, M.1
Taubert, S.2
Crawford, D.3
Libina, N.4
Lee, S.-J.5
Kenyon, C.6
-
4
-
-
33846418352
-
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
-
DOI 10.1111/j.1474-9726.2006.00266.x
-
Pan KZ, Palter JE, Rogers AN et al. Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 2007; 6:111-9. (Pubitemid 46140144)
-
(2007)
Aging Cell
, vol.6
, Issue.1
, pp. 111-119
-
-
Pan, K.Z.1
Palter, J.E.2
Rogers, A.N.3
Olsen, A.4
Chen, D.5
Lithgow, G.J.6
Kapahi, P.7
-
5
-
-
0037470539
-
Genetics and the specificity of the aging process
-
DOI 10.1126/science.1082358
-
Hekimi S, Guarente L. Genetics and the specificity of the aging process. Science 2003; 299:1351-4. (Pubitemid 36254640)
-
(2003)
Science
, vol.299
, Issue.5611
, pp. 1351-1354
-
-
Hekimi, S.1
Guarente, L.2
-
6
-
-
38949145803
-
A systematic look at an old problem
-
DOI 10.1038/451644a, PII 451644A
-
Kirkwood TBL. A systematic look at an old problem. Nature 2008; 451:644-7. (Pubitemid 351220553)
-
(2008)
Nature
, vol.451
, Issue.7179
, pp. 644-647
-
-
Kirkwood, T.B.L.1
-
7
-
-
70349330773
-
The Regulation of aging-does autophagy underlie longevity? trends
-
in press
-
Vellai T, Takács-Vellai K, Sass M et al. The regulation of aging-does autophagy underlie longevity? Trends Cell Biol 2009; in press.
-
(2009)
Cell Biol
-
-
Vellai, T.1
Takács-Vellai, K.2
Sass, M.3
-
8
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
DOI 10.1038/nature05291, PII NATURE05291
-
Rubinsztein DC. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 2006; 443:780-6. (Pubitemid 44622682)
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
9
-
-
63649161943
-
The ubiquitylation machinery of the endoplasmic reticulum
-
Hirsch C, Gauss R, Horn SC et al. The ubiquitylation machinery of the endoplasmic reticulum. Nature 2009; 485:453-60.
-
(2009)
Nature
, vol.485
, pp. 453-460
-
-
Hirsch, C.1
Gauss, R.2
Horn, S.C.3
-
10
-
-
0042330311
-
Apoptosis, necrosis and cellular senescence: Chaperone occupancy as a potential switch
-
Sõti C, Sreedhar AS, Csermely P. Apoptosis, necrosis and cellular senescence: chaperone occupancy as a potential switch. Aging Cell 2003; 2:39-45.
-
(2003)
Aging Cell
, vol.2
, pp. 39-45
-
-
Sõti, C.1
Sreedhar, A.S.2
Csermely, P.3
-
11
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
12
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
DOI 10.1038/nature06639, PII NATURE06639
-
Mizushima M, Levine B, Cuervo AM et al. Autophagy fights disease through cellular selfdigestion. Nature 2008; 451:1069-75. (Pubitemid 351317450)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
13
-
-
56349168452
-
Autophagy and aging: Keeping that old broom working
-
Cuervo AM. Autophagy and aging: keeping that old broom working. Trends Genet 2008; 24:604-12.
-
(2008)
Trends Genet
, vol.24
, pp. 604-612
-
-
Cuervo, A.M.1
-
14
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
DOI 10.1126/science.277.5328.942
-
Kimura KD, Tissenbaum HA, Liu Y et al. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 1997; 277:942-6. (Pubitemid 27366677)
-
(1997)
Science
, vol.277
, Issue.5328
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
15
-
-
0029768753
-
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
-
DOI 10.1038/382536a0
-
Morris JZ, Tissenbaum HA, Ruvkun G. A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature. 1996; 382:536-9. (Pubitemid 26260694)
-
(1996)
Nature
, vol.382
, Issue.6591
, pp. 536-539
-
-
Morris, J.Z.1
Tissenbaum, H.A.2
Ruvkun, G.3
-
16
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
DOI 10.1038/366461a0
-
Kenyon C, Chang J, Gensch E et al. A C. elegans mutant that lives twice as long as wild type. Nature 1993; 366:461-4. (Pubitemid 24013878)
-
(1993)
Nature
, vol.366
, Issue.6454
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
17
-
-
0028807085
-
The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans
-
Dorman JB, Albinder B, Shroyer T et al. The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans. Genetics 1995; 141:1399-406.
-
(1995)
Genetics
, vol.141
, pp. 1399-1406
-
-
Dorman, J.B.1
Albinder, B.2
Shroyer, T.3
-
18
-
-
0035815445
-
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
-
DOI 10.1126/science.1057987
-
Tatar M, Kopelman A, Epstein D et al. A mutant Drososphila insulin receptor homolog that extends lifespan and impairs neuroendocrine functions. Science 2001; 292:107-10. (Pubitemid 32289137)
-
(2001)
Science
, vol.292
, Issue.5514
, pp. 107-110
-
-
Tatar, M.1
Kopelman, A.2
Epstein, D.3
Tu, M.-P.4
Yin, C.-M.5
Garofalo, R.S.6
-
19
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M, Dupont J, Ducos B et al. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 2003; 421:125-6.
-
(2003)
Nature
, vol.421
, pp. 125-126
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
-
21
-
-
0035896557
-
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans
-
Miyadera H, Amino H, Hiraishi A et al. Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans. J Biol Chem 2001; 276:7713-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 7713-7716
-
-
Miyadera, H.1
Amino, H.2
Hiraishi, A.3
-
22
-
-
0037306190
-
Insulin/IGF and target of rapamycin signaling: A TOR de force in growth control
-
DOI 10.1016/S0962-8924(02)00042-9, PII S0962892402000429
-
Oldham S, Hafen E. Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol 2003; 13:79-85. (Pubitemid 36135889)
-
(2003)
Trends in Cell Biology
, vol.13
, Issue.2
, pp. 79-85
-
-
Oldham, S.1
Hafen, E.2
-
23
-
-
57649234905
-
Autophagy genes and ageing
-
Vellai T. Autophagy genes and ageing. Cell Death Differ 2009; 16:94-102.
-
(2009)
Cell Death Differ
, vol.16
, pp. 94-102
-
-
Vellai, T.1
-
24
-
-
0030657540
-
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
DOI 10.1126/science.278.5341.1319
-
Lin K, Dorman JB, Rodan A et al. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 1997; 278:1319-22. (Pubitemid 27495748)
-
(1997)
Science
, vol.278
, Issue.5341
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
25
-
-
0030659557
-
The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
DOI 10.1038/40194
-
Ogg S, Paradis S, Gottlieb S et al. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 1997; 389:994-9. (Pubitemid 27485694)
-
(1997)
Nature
, vol.389
, Issue.6654
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
Ruvkun, G.7
-
26
-
-
2942563805
-
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
-
DOI 10.1038/nature02549
-
Hwangbo DS, Gersham B, Tu M-P et al. Drosophila dFOXO controls lifespan and regulates insulinsignalling in brain and fat body. Nature 2004; 429:562-6. (Pubitemid 38737660)
-
(2004)
Nature
, vol.429
, Issue.6991
, pp. 562-566
-
-
Hwangbo, D.S.1
Garsham, B.2
Tu, M.-P.3
Palmer, M.4
Tatar, M.5
-
27
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
DOI 10.1038/414799a
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001;414:799-806. (Pubitemid 34000783)
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
28
-
-
0242539698
-
The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
-
Jünger MA, Rintelen F, Stocker H et al. The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J Biol 2003; 2:20.
-
(2003)
J Biol
, vol.2
, pp. 20
-
-
Jünger, M.A.1
Rintelen, F.2
Stocker, H.3
-
29
-
-
0035830846
-
Characterization of the initiation factor eIF2B and its regulation in Drosophila melanogaster
-
Williams DD, Pavitt GD, Proud CG. Characterization of the initiation factor eIF2B and its regulation in Drosophila melanogaster. 2J Biol Chem 2003; 76:3733-3742.
-
(2003)
2J Biol Chem
, vol.76
, pp. 3733-3742
-
-
Williams, D.D.1
Pavitt, G.D.2
Proud, C.G.3
-
30
-
-
0442323560
-
Tuberous sclerosis complex: From Drosophila to human disease
-
DOI 10.1016/j.tcb.2003.12.006
-
Pan D, Dong J, Zhang Y et al. Tuberous sclerosis complex: from Drosophila to human disease. Trends Cell Biol 2004; 14:78-85. (Pubitemid 38186641)
-
(2004)
Trends in Cell Biology
, vol.14
, Issue.2
, pp. 78-85
-
-
Pan, D.1
Dong, J.2
Zhang, Y.3
Gao, X.4
-
31
-
-
10644282295
-
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
-
DOI 10.1101/gad.1255404
-
Apfeld J, O'Connor G, McDonagh T et al. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev 2004; 18:3004-9. (Pubitemid 39658169)
-
(2004)
Genes and Development
, vol.18
, Issue.24
, pp. 3004-3009
-
-
Apfeld, J.1
O'Connor, G.2
McDonagh, T.3
DiStefano, P.S.4
Curtis, R.5
-
32
-
-
0642367846
-
Influence of TOR kinase on lifespan in C. elegans
-
Vellai T, Takács-Vellai K, Zhang Y et al. Genetics: influence of TOR kinase on lifespan in C. elegans. Nature 2003; 426:620. (Pubitemid 38009359)
-
(2003)
Nature
, vol.426
, Issue.6967
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.L.4
Orosz, L.5
Muller, F.6
-
33
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
DOI 10.1242/dev.01255
-
Jia K, Chen D, Riddle DL. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 2004; 131:3897-906. (Pubitemid 39232150)
-
(2004)
Development
, vol.131
, Issue.16
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.L.3
-
34
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
DOI 10.1016/S0092-8674(02)00808-5
-
Kim DH, Sarbassov DD, Ali S et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002; 110:163-75. (Pubitemid 34876545)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim, D.-H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
35
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
DOI 10.1016/S0092-8674(02)00833-4
-
Hara K, Maruki Y, Long X et al. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 2002; 110:177-89. (Pubitemid 34876546)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.-I.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
36
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
-
DOI 10.1016/j.cub.2004.03.059, PII S0960982204002386
-
Kapahi P, Zid BM, Harper T et al. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr Biol 2004; 14:885-90. (Pubitemid 38800910)
-
(2004)
Current Biology
, vol.14
, Issue.10
, pp. 885-890
-
-
Kapahi, P.1
Zid, B.M.2
Harper, T.3
Koslover, D.4
Sapin, V.5
Benzer, S.6
-
37
-
-
27744511769
-
Cell biology: Regulation of yeast replicative life span by TOR and Sch9 response to nutrients
-
DOI 10.1126/science.1115535
-
Kaeberlein M, Powers III WR, Steffen KK et al. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 2005; 310:1193-96. (Pubitemid 41681747)
-
(2005)
Science
, vol.310
, Issue.5751
, pp. 1193-1196
-
-
Kaeberlein, M.1
Powers III, R.W.2
Steffen, K.K.3
Westman, E.A.4
Hu, D.5
Dang, N.6
Kerr, E.O.7
Kirkland, K.T.8
Fields, S.9
Kennedy, B.K.10
-
38
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460:392-5.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
-
39
-
-
0034306249
-
Amino acid regulation of gene expression
-
Fafournoux P, Bruhat A, Jousse C. Amino acid regulation of gene expression. Biochem J 2000; 351:1-12.
-
(2000)
Biochem J
, vol.351
, pp. 1-12
-
-
Fafournoux, P.1
Bruhat, A.2
Jousse, C.3
-
40
-
-
0032834055
-
eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
-
DOI 10.1146/annurev.biochem.68.1.913
-
Gingras AC, Raught B, Sonenberg N. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem 1999; 68:913-63. (Pubitemid 29449212)
-
(1999)
Annual Review of Biochemistry
, vol.68
, pp. 913-963
-
-
Gingras, A.-C.1
Raught, B.2
Sonenberg, N.3
-
41
-
-
38949137849
-
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor and Sch9
-
Wei M, Fabrizio P, Hu J et al. Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor and Sch9. PLoS Genet 2008; 4:e13.
-
(2008)
PLoS Genet
, vol.4
-
-
Wei, M.1
Fabrizio, P.2
Hu, J.3
-
42
-
-
0027288587
-
The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: Implications for insulin control of ras signalling
-
Skolnik EY, Lee CH, Batzer A et al. The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling. EMBO J 1993; 12:1929-36. (Pubitemid 23157709)
-
(1993)
EMBO Journal
, vol.12
, Issue.5
, pp. 1929-1936
-
-
Skolnik, E.Y.1
Lee, C.-H.2
Batzer, A.3
Vicentini, L.M.4
Zhou, M.5
Daly, R.6
Myers Jr., M.J.7
Backer, J.M.8
Ullrich, A.9
White, M.F.10
Schlessinger, J.11
-
43
-
-
1642491749
-
Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae
-
DOI 10.1016/S0014-5793(03)01462-5
-
Fabrizio P, Pletcher SD, Minois N et al. Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae. FEBS Lett 2004; 557:136-42. (Pubitemid 38115884)
-
(2004)
FEBS Letters
, vol.557
, Issue.1-3
, pp. 136-142
-
-
Fabrizio, P.1
Pletcher, S.D.2
Minois, N.3
Vaupel, J.W.4
Longo, V.D.5
-
44
-
-
2442645050
-
The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae
-
DOI 10.1074/jbc.M400272200
-
Budovskaya YV, Stephan JS, Reggiori F et al. The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae. J Biol Chem 2004; 279:20663-71. (Pubitemid 38656461)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.20
, pp. 20663-20671
-
-
Budovskaya, Y.V.1
Stephan, J.S.2
Reggiori, F.3
Klionsky, D.J.4
Herman, P.K.5
-
45
-
-
34447528668
-
Type 5 Adenylyl Cyclase Disruption Increases Longevity and Protects Against Stress
-
DOI 10.1016/j.cell.2007.05.038, PII S0092867407006770
-
Yan L, Vatner DE, O'Connor JP et al. Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell 2007; 130:247-58. (Pubitemid 47081133)
-
(2007)
Cell
, vol.130
, Issue.2
, pp. 247-258
-
-
Yan, L.1
Vatner, D.E.2
O'Connor, J.P.3
Ivessa, A.4
Ge, H.5
Chen, W.6
Hirotani, S.7
Ishikawa, Y.8
Sadoshima, J.9
Vatner, S.F.10
-
46
-
-
0035881727
-
Suppression of cap-dependent translation in mitosis
-
DOI 10.1101/gad.889201
-
Pyronnet S, Dostie J, Sonenberg N. Suppression of cap-dependent translation in mitosis. Genes Dev 2001; 15:2083-93. (Pubitemid 32762052)
-
(2001)
Genes and Development
, vol.15
, Issue.16
, pp. 2083-2093
-
-
Pyronnet, S.1
Dostie, J.2
Sonenberg, N.3
-
47
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
DOI 10.1038/nature02006
-
Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-b family signalling. Nature 2003; 425:577-84. (Pubitemid 37280136)
-
(2003)
Nature
, vol.425
, Issue.6958
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
48
-
-
34848868499
-
The C. elegans TGF-β Dauer Pathway Regulates Longevity via Insulin Signaling
-
DOI 10.1016/j.cub.2007.08.058, PII S0960982207019148
-
Shaw WM, Luo S, Landis J et al. The C. elegans TGF-β dauer pathway regulates longevity via insulin signalling. Curr Biol 2007; 17:1635-45. (Pubitemid 47503810)
-
(2007)
Current Biology
, vol.17
, Issue.19
, pp. 1635-1645
-
-
Shaw, W.M.1
Luo, S.2
Landis, J.3
Ashraf, J.4
Murphy, C.T.5
-
49
-
-
0032589736
-
Specificity of TGFβ signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans
-
Krishna S, Maduzia LL, Padgett RV. Specificity of TGFb signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans. Development 1999; 126:251-60. (Pubitemid 29083963)
-
(1999)
Development
, vol.126
, Issue.2
, pp. 251-260
-
-
Krishna, S.1
Maduzia, L.L.2
Padgett, R.W.3
-
50
-
-
43949098273
-
Regulation of cell growth by autophagy
-
Vellai T, Bicsák B, Tóth ML et al. Regulation of cell growth by autophagy. Autophagy 2008; 4:507-9. (Pubitemid 351705147)
-
(2008)
Autophagy
, vol.4
, Issue.4
, pp. 507-509
-
-
Vellai, T.1
Bicsak, B.2
Toth, M.L.3
Takacs-Vellai, K.4
Kovacs, A.L.5
-
52
-
-
17044408768
-
JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
-
Wang MC, Bohmann D, Jasper H. JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 2005; 121:115-25.
-
(2005)
Cell
, vol.121
, pp. 115-125
-
-
Wang, M.C.1
Bohmann, D.2
Jasper, H.3
-
53
-
-
15444371989
-
JNK regulates lifespan in Caenorhabiditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
-
DOI 10.1073/pnas.0500749102
-
Oh SW, Mukhopadhyay A, Svrzikapa N et al. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor DAF-16. Proc Natl Acad Sci USA 2005; 102:4494-9. (Pubitemid 40397140)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.12
, pp. 4494-4499
-
-
Oh, S.W.1
Mukhopadhyay, A.2
Svrzikapa, N.3
Jiang, F.4
Davis, R.J.5
Tissenbaum, H.A.6
-
54
-
-
0028802746
-
A hierarchy of ATP-consuming processes in mammalian cells
-
Buttgereit F, Brand MD. A hierarchy of ATP-consuming processes in mammalian cells. Biochem J 1995; 312:163-7.
-
(1995)
Biochem J
, vol.312
, pp. 163-167
-
-
Buttgereit, F.1
Brand, M.D.2
-
55
-
-
36749081539
-
mTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcriptional complex
-
DOI 10.1038/nature06322, PII NATURE06322
-
Cunningham JT, Rodgers JT, Arlow DH et al. mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature 2007; 450:736-40. (Pubitemid 350207689)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
Mootha, V.K.5
Puigserver, P.6
-
56
-
-
0037147103
-
Rates of behavior and aging specified by mitochondrial function during development
-
Dillin A, Hsu AL, Arantes-Oliveira N et al. Rates of behavior and aging specified by mitochondrial function during development. Science 2002; 298:2398-401.
-
(2002)
Science
, vol.298
, pp. 2398-23401
-
-
Dillin, A.1
Hsu, A.L.2
Arantes-Oliveira, N.3
-
57
-
-
0037228016
-
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
-
DOI 10.1038/ng1056
-
Lee SS, Lee RY, Fraser AG et al. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat Genet 2003; 33:40-8. (Pubitemid 36068680)
-
(2003)
Nature Genetics
, vol.33
, Issue.1
, pp. 40-48
-
-
Lee, S.S.1
Lee, R.Y.N.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Ruvkun, G.6
-
58
-
-
36448968532
-
FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells
-
DOI 10.1016/j.cmet.2007.11.004, PII S1550413107003397
-
Zhao J, Brault JJ, Schild A et al. FoxO3 co-ordinately activates protein degradation by the autophagic/ lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 2007; 6:472-83. (Pubitemid 350163056)
-
(2007)
Cell Metabolism
, vol.6
, Issue.6
, pp. 472-483
-
-
Zhao, J.1
Brault, J.J.2
Schild, A.3
Cao, P.4
Sandri, M.5
Schiaffino, S.6
Lecker, S.H.7
Goldberg, A.L.8
-
59
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
DOI 10.1126/science.1087782
-
Meléndez A, Tallóczy Z, Seaman M et al. Autophagy genes are essential for dauer development and life span extension in C. elegans. Science 2003; 301:1387-91. (Pubitemid 37075816)
-
(2003)
Science
, vol.301
, Issue.5638
, pp. 1387-1391
-
-
Melendez, A.1
Talloczy, Z.2
Seaman, M.3
Eskelinen, E.-L.4
Hall, D.H.5
Levine, B.6
-
60
-
-
41449102024
-
Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans
-
Tóth ML, Sigmond T, Borsos É et al. Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. Autophagy 2008; 4:330-8. (Pubitemid 351458094)
-
(2008)
Autophagy
, vol.4
, Issue.3
, pp. 330-338
-
-
Toth, M.L.1
Sigmond, T.2
Borsos, E.3
Barna, J.4
Erdelyi, P.5
Takacs-Vellai, K.6
Orosz, L.7
Kovacs, A.L.8
Csikos, G.9
Sass, M.10
Vellai, T.11
-
61
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
-
Hansen M, Chandra A, Mitic LL et al. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet 2008; 4:e24.
-
(2008)
PLoS Genet
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
-
62
-
-
34250882745
-
Regulation of Caenorhabditis elegans life span by a proteasomal E3 ligase complex
-
Ghazi A, Henis-Korenblit S, Kenyon C. Regulation of Caenorhabditis elegans life span by a proteasomal E3 ligase complex. Proc Natl Acad Sci USA 2007; 104:5947-52.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5947-552
-
-
Ghazi, A.1
Henis-Korenblit, S.2
Kenyon, C.3
|