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Volumn 25, Issue 2, 2007, Pages 112-117

Basic mechanisms of the aging gastrointestinal tract

Author keywords

Gastrointestinal aging; Geriatrics; Motor and histological changes

Indexed keywords

AGING; ANOREXIA; BACTERIAL OVERGROWTH; CARCINOGENESIS; CONSTIPATION; DIGESTIVE SYSTEM CANCER; DYSPEPSIA; DYSPHAGIA; ESOPHAGUS MOTILITY; GASTROINTESTINAL DISEASE; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL TRACT; GASTROINTESTINAL TRACT FUNCTION; GERIATRIC ASSESSMENT; GERIATRIC PATIENT; HISTOCHEMISTRY; HISTOPATHOLOGY; HUMAN; INTESTINE TRANSIT TIME; MOTOR PERFORMANCE; PREVALENCE; PRIORITY JOURNAL; REVIEW; STOMACH EMPTYING; STOMACH SECRETION;

EID: 34247534646     PISSN: 02572753     EISSN: None     Source Type: Journal    
DOI: 10.1159/000099474     Document Type: Review
Times cited : (135)

References (40)
  • 1
    • 0029793118 scopus 로고    scopus 로고
    • The influence of aging on oesophageal motility after ingestion of liquids with different viscosities
    • Ferriolli E, Dantas RO, Oliveira RB, et al: The influence of aging on oesophageal motility after ingestion of liquids with different viscosities. Eur J Gastroenterol Hepatol 1996;8:793-798.
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 793-798
    • Ferriolli, E.1    Dantas, R.O.2    Oliveira, R.B.3
  • 2
    • 0031254558 scopus 로고    scopus 로고
    • The aging esophagus
    • Tack J, Vantrappen G: The aging esophagus. Gut 1997;41:422-424.
    • (1997) Gut , vol.41 , pp. 422-424
    • Tack, J.1    Vantrappen, G.2
  • 3
    • 0028837092 scopus 로고
    • Nerve cell loss in the myenteric plexus of the human esophagus in relation to age: A preliminary investigation
    • Meciano Filho J, Carvalho VC, de Souza RR: Nerve cell loss in the myenteric plexus of the human esophagus in relation to age: a preliminary investigation. Gerontology 1995;41:18-21.
    • (1995) Gerontology , vol.41 , pp. 18-21
    • Meciano Filho, J.1    Carvalho, V.C.2    de Souza, R.R.3
  • 4
    • 0031775051 scopus 로고    scopus 로고
    • Aging, esophageal motility and gastroesophageal reflux disease
    • Ferriolli E, Oliveira RB, Matsuda NM, et al: Aging, esophageal motility and gastroesophageal reflux disease. J Am Geriatr Soc 1998;46:1534-1537.
    • (1998) J Am Geriatr Soc , vol.46 , pp. 1534-1537
    • Ferriolli, E.1    Oliveira, R.B.2    Matsuda, N.M.3
  • 5
    • 0032977315 scopus 로고    scopus 로고
    • Deterioration of esophageal motility with age: A manometric study of 79 healthy subjects
    • Grande L, Lacima G, Ros E, et al: Deterioration of esophageal motility with age: a manometric study of 79 healthy subjects. Am J Gastroenterol 1999;94:1795-1801.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1795-1801
    • Grande, L.1    Lacima, G.2    Ros, E.3
  • 6
    • 1542359600 scopus 로고    scopus 로고
    • Effects of aging on gastrointestinal motor function
    • Madsen JL, Graff J: Effects of aging on gastrointestinal motor function. Age Aging 2004;33:154-159.
    • (2004) Age Aging , vol.33 , pp. 154-159
    • Madsen, J.L.1    Graff, J.2
  • 7
    • 0026744267 scopus 로고
    • Effects of gender, age, and body mass index on gastrointestinal transit times
    • Madsen JL: Effects of gender, age, and body mass index on gastrointestinal transit times. Dig Dis Sci 1992;37:1548-1553.
    • (1992) Dig Dis Sci , vol.37 , pp. 1548-1553
    • Madsen, J.L.1
  • 9
    • 0032838741 scopus 로고    scopus 로고
    • Effects of aging and gastric lipolysis on gastric emptying of lipid in liquid meal
    • Nakae Y, Onouchi H, Kagaya M, et al: Effects of aging and gastric lipolysis on gastric emptying of lipid in liquid meal. J Gastroenterol 1999;34:445-449.
    • (1999) J Gastroenterol , vol.34 , pp. 445-449
    • Nakae, Y.1    Onouchi, H.2    Kagaya, M.3
  • 10
    • 0035806343 scopus 로고    scopus 로고
    • As the gut ages: Timetables for aging of innervation vary by organ in the Fisher 344 rat
    • Phillips RJ, Powley TL: As the gut ages: timetables for aging of innervation vary by organ in the Fisher 344 rat. J Comp Neurol 2001;434:358-377.
    • (2001) J Comp Neurol , vol.434 , pp. 358-377
    • Phillips, R.J.1    Powley, T.L.2
  • 11
    • 0033083551 scopus 로고    scopus 로고
    • Ageinduced changes in the enteric nervous system in the mouse
    • El-Salhy M, Sandstrom O, Holmlund F: Ageinduced changes in the enteric nervous system in the mouse. Mech Aging Dev 1999;107:93-103.
    • (1999) Mech Aging Dev , vol.107 , pp. 93-103
    • El-Salhy, M.1    Sandstrom, O.2    Holmlund, F.3
  • 12
    • 0038488561 scopus 로고    scopus 로고
    • Aging of the myenteric plexus: Neuronal loss is specific to cholinergic neurons
    • Phillips RJ, Kieffer EJ, Powley TL: Aging of the myenteric plexus: neuronal loss is specific to cholinergic neurons. Auton Neurosci 2003;106:69-83.
    • (2003) Auton Neurosci , vol.106 , pp. 69-83
    • Phillips, R.J.1    Kieffer, E.J.2    Powley, T.L.3
  • 13
    • 0030739407 scopus 로고    scopus 로고
    • A preliminary investigation of the effects of aging on the nerve cell number in the myenteric ganglia of the human colon
    • Gomes OA, de Souza RR, Liberti EA: A preliminary investigation of the effects of aging on the nerve cell number in the myenteric ganglia of the human colon. Gerontology 1997;43:210-217.
    • (1997) Gerontology , vol.43 , pp. 210-217
    • Gomes, O.A.1    de Souza, R.R.2    Liberti, E.A.3
  • 14
    • 0034634464 scopus 로고    scopus 로고
    • Decreased expression of nitric oxide synthase in the colonic myenteric plexus of aged rats
    • Takahashi T, Qoubaitary A, Owyang C, et al: Decreased expression of nitric oxide synthase in the colonic myenteric plexus of aged rats. Brain Res 2000;883:15-21.
    • (2000) Brain Res , vol.883 , pp. 15-21
    • Takahashi, T.1    Qoubaitary, A.2    Owyang, C.3
  • 15
    • 0028923133 scopus 로고
    • Orally administered opioid antagonists reverse both μ- and κ-opioid agonist delay of gastrointestinal transit in the guinea pig
    • Culpepper-Morgan JA, Holt PR, LaRoche D, et al: Orally administered opioid antagonists reverse both μ- and κ-opioid agonist delay of gastrointestinal transit in the guinea pig. Life Sci 1995;56:1187-1192.
    • (1995) Life Sci , vol.56 , pp. 1187-1192
    • Culpepper-Morgan, J.A.1    Holt, P.R.2    LaRoche, D.3
  • 16
    • 0028137425 scopus 로고
    • Evidence for age-associated reduction in acetylcholine release and smooth muscle response in the rat colon
    • Roberts D, Gelperin D, Wiley JW: Evidence for age-associated reduction in acetylcholine release and smooth muscle response in the rat colon. Am J Physiol 1994;267:G515-G522.
    • (1994) Am J Physiol , vol.267
    • Roberts, D.1    Gelperin, D.2    Wiley, J.W.3
  • 17
    • 0033937838 scopus 로고    scopus 로고
    • Differential effects of maturation on nicotinic- and muscarinic receptor-induced ion secretion in guinea pig distal colon
    • Powell AR, Reddix RA: Differential effects of maturation on nicotinic- and muscarinic receptor-induced ion secretion in guinea pig distal colon. Proc Soc Exp Biol Med 2000;224:147-151.
    • (2000) Proc Soc Exp Biol Med , vol.224 , pp. 147-151
    • Powell, A.R.1    Reddix, R.A.2
  • 18
    • 0027509745 scopus 로고
    • Gastrointestinal proliferation and aging
    • Atillasoy E, Holt PR: Gastrointestinal proliferation and aging. J Gerontol 1993;48:B43-B49.
    • (1993) J Gerontol , vol.48
    • Atillasoy, E.1    Holt, P.R.2
  • 19
    • 0034857113 scopus 로고    scopus 로고
    • Aging is associated with increased proliferation and decreased apoptosis in the colonic mucosa
    • Xiao ZQ, Moragoda L, Jaszewski R, et al: Aging is associated with increased proliferation and decreased apoptosis in the colonic mucosa. Mech Aging Dev 2001;122:1849-1864.
    • (2001) Mech Aging Dev , vol.122 , pp. 1849-1864
    • Xiao, Z.Q.1    Moragoda, L.2    Jaszewski, R.3
  • 21
    • 16844386490 scopus 로고    scopus 로고
    • Regulation of gastrointestinal mucosal growth during aging
    • Majumdar AP: Regulation of gastrointestinal mucosal growth during aging. J Physiol Pharmacol 2003;54:S4:143-154.
    • (2003) J Physiol Pharmacol , vol.54 , Issue.S4 , pp. 143-154
    • Majumdar, A.P.1
  • 22
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 23
    • 0030771935 scopus 로고    scopus 로고
    • Gastric acidity in older adults
    • Hurvitz A, Brady DA, Schaal E, et al: Gastric acidity in older adults. JAMA 1997;278:659-662.
    • (1997) JAMA , vol.278 , pp. 659-662
    • Hurvitz, A.1    Brady, D.A.2    Schaal, E.3
  • 24
    • 6744229782 scopus 로고    scopus 로고
    • Effect of age and Helicobacter pylori infection on gastric acid secretion
    • Haruma K, Kamada T, Kawaguchi H, et al: Effect of age and Helicobacter pylori infection on gastric acid secretion. J Gastroenterol Hepatol 2000;15:277-283.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 277-283
    • Haruma, K.1    Kamada, T.2    Kawaguchi, H.3
  • 25
    • 0036034897 scopus 로고    scopus 로고
    • Helicobacter pylori infection in geriatrics
    • Pilotto A, Salles N: Helicobacter pylori infection in geriatrics. Helicobacter 2002;7:56-62.
    • (2002) Helicobacter , vol.7 , pp. 56-62
    • Pilotto, A.1    Salles, N.2
  • 26
    • 0035660980 scopus 로고    scopus 로고
    • Atrophic gastritis and intestinal metaplasia in Japan: Results of a large multicenter study
    • Asaka M, Sugiyama T, Nobuta A, et al: Atrophic gastritis and intestinal metaplasia in Japan: results of a large multicenter study. Helicobacter 2001;6:294-299.
    • (2001) Helicobacter , vol.6 , pp. 294-299
    • Asaka, M.1    Sugiyama, T.2    Nobuta, A.3
  • 27
    • 0038315313 scopus 로고    scopus 로고
    • Prevalence of small bowel bacterial overgrowth and its association with nutrition intake in nonhospitalized older adults
    • Parlesak A, Klein B, Schecher K, et al: Prevalence of small bowel bacterial overgrowth and its association with nutrition intake in nonhospitalized older adults. J Am Geriatr Soc 2003;51:768-773.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 768-773
    • Parlesak, A.1    Klein, B.2    Schecher, K.3
  • 28
    • 0032958024 scopus 로고    scopus 로고
    • Small bowel bacterial overgrowth in subjects living in residential care homes
    • Lewis SJ, Potts LF, Malhotra R, et al: Small bowel bacterial overgrowth in subjects living in residential care homes. Age Aging 1999;28:181-185.
    • (1999) Age Aging , vol.28 , pp. 181-185
    • Lewis, S.J.1    Potts, L.F.2    Malhotra, R.3
  • 30
    • 0026595090 scopus 로고
    • Protein-bound cobalamin absorption declines in the elderly
    • Scarlet JD, Read H, O'Dea K: Protein-bound cobalamin absorption declines in the elderly. Am J Hematol 1992;39:79-83.
    • (1992) Am J Hematol , vol.39 , pp. 79-83
    • Scarlet, J.D.1    Read, H.2    O'Dea, K.3
  • 31
    • 0034621704 scopus 로고    scopus 로고
    • Helicobacter pylori : Is it a novel causative agent in vitamin B 12 deficiency?
    • Kaptan K, Beyan C, Ural A, et al: Helicobacter pylori : is it a novel causative agent in vitamin B 12 deficiency? Arch Intern Med 2000;160:1349-1353.
    • (2000) Arch Intern Med , vol.160 , pp. 1349-1353
    • Kaptan, K.1    Beyan, C.2    Ural, A.3
  • 32
    • 0034967791 scopus 로고    scopus 로고
    • Helicobacter pylori eradication attenuates oxidative stress in human gastric mucosa
    • Pignatelli B, Bancel B, Plummer M, et al: Helicobacter pylori eradication attenuates oxidative stress in human gastric mucosa. Am J Gastroenterol 2001;96:1758-1766.
    • (2001) Am J Gastroenterol , vol.96 , pp. 1758-1766
    • Pignatelli, B.1    Bancel, B.2    Plummer, M.3
  • 33
    • 18344366874 scopus 로고    scopus 로고
    • Role of mitochondria in oxidative stress and aging
    • Lenaz G, Bovina C, D'Aurelio M, et al: Role of mitochondria in oxidative stress and aging. Ann NY Acad Sci 2002 959: 199-213.
    • (2002) Ann NY Acad Sci , vol.959 , pp. 199-213
    • Lenaz, G.1    Bovina, C.2    D'Aurelio, M.3
  • 34
    • 0033637971 scopus 로고    scopus 로고
    • Regulation of growth and apoptosis of cultured guinea pig gastric mucosal cells by mitogenic oxidase 1
    • Teshima S, Kutsumi H, Kawahara T, et al: Regulation of growth and apoptosis of cultured guinea pig gastric mucosal cells by mitogenic oxidase 1. Am J Physiol 2000;279:G1169-G1176.
    • (2000) Am J Physiol , vol.279
    • Teshima, S.1    Kutsumi, H.2    Kawahara, T.3
  • 35
    • 0032552112 scopus 로고    scopus 로고
    • The stomach is a source of leptin
    • Bado A, Levasseur S, Attoub S, et al: The stomach is a source of leptin. Nature 1998;394:790-793.
    • (1998) Nature , vol.394 , pp. 790-793
    • Bado, A.1    Levasseur, S.2    Attoub, S.3
  • 36
    • 0034878831 scopus 로고    scopus 로고
    • Gastric leptin and Helicobacter pylori infection
    • Azuma T, Suto H, Ito Y, et al: Gastric leptin and Helicobacter pylori infection. Gut 2001;49:324-329.
    • (2001) Gut , vol.49 , pp. 324-329
    • Azuma, T.1    Suto, H.2    Ito, Y.3
  • 37
    • 0038639060 scopus 로고    scopus 로고
    • Plasma ghrelin following cure of Helicobacter pylori
    • Nwokolo CU, Freshwater DA, O'Hare P, et al: Plasma ghrelin following cure of Helicobacter pylori. Gut 2003;52:637-640.
    • (2003) Gut , vol.52 , pp. 637-640
    • Nwokolo, C.U.1    Freshwater, D.A.2    O'Hare, P.3
  • 38
    • 0022559689 scopus 로고
    • Aging and small-bowel mucosa: A morphometric study
    • Corazza GR, Frazzoni M, Gatto MR, et al: Aging and small-bowel mucosa: a morphometric study. Gerontology 1986;32:60-65.
    • (1986) Gerontology , vol.32 , pp. 60-65
    • Corazza, G.R.1    Frazzoni, M.2    Gatto, M.R.3
  • 40
    • 0027459209 scopus 로고
    • Effects of aging on intestinal lipid absorption
    • Holt PR, Balint JA: Effects of aging on intestinal lipid absorption. Am J Physiol 1993;264:G1-G6.
    • (1993) Am J Physiol , vol.264
    • Holt, P.R.1    Balint, J.A.2


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