FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development

Journal of Pathology

Volumn 224, Issue 2, 2011, Pages 180-189

  Davis, Hayley ^a   Lewis, Annabelle ^a   Spencer Dene, Bradley ^b   Tateossian, Hilda ^c   Stamp, Gordon ^b   Behrens, Axel ^b   Tomlinson, Ian ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

cancer; Fbxw7; lung development; TGF ; WD40

Indexed keywords

ARGININE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CLEFT PALATE; EMBRYO; EMBRYO DEVELOPMENT; EYELID DISEASE; FBXW7 GENE; LUNG DEVELOPMENT; LUNG DISEASE; MOUSE; NONHUMAN; NULL ALLELE; POINT MUTATION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ABNORMALITIES, MULTIPLE; ALLELES; AMINO ACID SEQUENCE; ANIMALS; ARGININE; CELL CYCLE PROTEINS; DISEASE MODELS, ANIMAL; F-BOX PROTEINS; HUMANS; LUNG; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NEOPLASMS; POINT MUTATION; PULMONARY ALVEOLI; SEQUENCE ALIGNMENT; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN-PROTEIN LIGASES;

EID: 79955845570     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2874     Document Type: Article

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