-
1
-
-
0035921928
-
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines
-
10.1038/35095068 11565033
-
Moberg KH Bell DW Wahrer DC Haber DA Hariharan IK Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines Nature 2001 413 6853 311-316 10.1038/35095068 11565033
-
(2001)
Nature
, vol.413
, pp. 311-316
-
-
Moberg, K.H.1
Bell, D.W.2
Wahrer, D.C.3
Haber, D.A.4
Hariharan, I.K.5
-
2
-
-
0035812709
-
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
-
10.1126/science.1065203 11533444
-
Koepp DM Schaefer LK Ye X Keyomarsi K Chu C Harper JW Elledge SJ Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase Science 2001 294 5540 173-177 10.1126/science.1065203 11533444
-
(2001)
Science
, vol.294
, Issue.5540
, pp. 173-177
-
-
Koepp, D.M.1
Schaefer, L.K.2
Ye, X.3
Keyomarsi, K.4
Chu, C.5
Harper, J.W.6
Elledge, S.J.7
-
3
-
-
0035921849
-
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
-
10.1038/35095076 11565034
-
Strohmaier H Spruck CH Kaiser P Won KA Sangfelt O Reed SI Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line Nature 2001 413 6853 316-322 10.1038/35095076 11565034
-
(2001)
Nature
, vol.413
, Issue.6853
, pp. 316-322
-
-
Strohmaier, H.1
Spruck, C.H.2
Kaiser, P.3
Won, K.A.4
Sangfelt, O.5
Reed, S.I.6
-
4
-
-
2942650133
-
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
-
428477 15150404 10.1073/pnas.0402770101
-
Welcker M Orian A Jin J Grim JE Harper JW Eisenman RN Clurman BE The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation Proc Natl Acad Sci U S A 2004 101 24 9085-9090 428477 15150404 10.1073/pnas.0402770101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.24
, pp. 9085-9090
-
-
Welcker, M.1
Orian, A.2
Jin, J.3
Grim, J.E.4
Harper, J.W.5
Eisenman, R.N.6
Clurman, B.E.7
-
5
-
-
2942614705
-
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
-
424394 15103331 10.1038/sj.emboj.7600217
-
Yada M Hatakeyama S Kamura T Nishiyama M Tsunematsu R Imaki H Ishida N Okumura F Nakayama K Nakayama KI Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7 Embo J 2004 23 10 2116-2125 424394 15103331 10.1038/sj.emboj.7600217
-
(2004)
Embo J
, vol.23
, Issue.10
, pp. 2116-2125
-
-
Yada, M.1
Hatakeyama, S.2
Kamura, T.3
Nishiyama, M.4
Tsunematsu, R.5
Imaki, H.6
Ishida, N.7
Okumura, F.8
Nakayama, K.9
Nakayama, K.I.10
-
6
-
-
2642549141
-
The Drosophila F box protein archipelago regulates dMyc protein levels in vivo
-
10.1016/j.cub.2004.04.040 15182669
-
Moberg KH Mukherjee A Veraksa A Artavanis-Tsakonas S Hariharan IK The Drosophila F box protein archipelago regulates dMyc protein levels in vivo Curr Biol 2004 14 11 965-974 10.1016/j.cub.2004.04.040 15182669
-
(2004)
Curr Biol
, vol.14
, Issue.11
, pp. 965-974
-
-
Moberg, K.H.1
Mukherjee, A.2
Veraksa, A.3
Artavanis-Tsakonas, S.4
Hariharan, I.K.5
-
7
-
-
1342275412
-
The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling
-
10.1126/science.1092880 14739463
-
Nateri AS Riera-Sans L Da Costa C Behrens A The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling Science 2004 303 5662 1374-1378 10.1126/science.1092880 14739463
-
(2004)
Science
, vol.303
, Issue.5662
, pp. 1374-1378
-
-
Nateri, A.S.1
Riera-Sans, L.2
Da Costa, C.3
Behrens, A.4
-
8
-
-
0030659821
-
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
-
316751 9389650
-
Hubbard EJ Wu G Kitajewski J Greenwald I sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins Genes Dev 1997 11 23 3182-3193 316751 9389650
-
(1997)
Genes Dev
, vol.11
, Issue.23
, pp. 3182-3193
-
-
Hubbard, E.J.1
Wu, G.2
Kitajewski, J.3
Greenwald, I.4
-
9
-
-
0032416732
-
Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin
-
28122 9861048 10.1073/pnas.95.26.15787
-
Wu G Hubbard EJ Kitajewski JK Greenwald I Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin Proc Natl Acad Sci U S A 1998 95 26 15787-15791 28122 9861048 10.1073/pnas.95.26.15787
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.26
, pp. 15787-15791
-
-
Wu, G.1
Hubbard, E.J.2
Kitajewski, J.K.3
Greenwald, I.4
-
10
-
-
23844530704
-
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7)
-
10.1016/j.cmet.2005.04.010 16054087
-
Sundqvist A Bengoechea-Alonso MT Ye X Lukiyanchuk V Jin J Harper JW Ericsson J Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7) Cell Metab 2005 1 6 379-391 10.1016/j.cmet.2005.04.010 16054087
-
(2005)
Cell Metab
, vol.1
, Issue.6
, pp. 379-391
-
-
Sundqvist, A.1
Bengoechea-Alonso, M.T.2
Ye, X.3
Lukiyanchuk, V.4
Jin, J.5
Harper, J.W.6
Ericsson, J.7
-
11
-
-
0035969559
-
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
-
10.1038/35107009 11734846
-
Nash P Tang X Orlicky S Chen Q Gertler FB Mendenhall MD Sicheri F Pawson T Tyers M Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication Nature 2001 414 6863 514-521 10.1038/ 35107009 11734846
-
(2001)
Nature
, vol.414
, Issue.6863
, pp. 514-521
-
-
Nash, P.1
Tang, X.2
Orlicky, S.3
Chen, Q.4
Gertler, F.B.5
Mendenhall, M.D.6
Sicheri, F.7
Pawson, T.8
Tyers, M.9
-
12
-
-
0038420033
-
hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53
-
10.1111/j.1349-7006.2003.tb01460.x 12824889
-
Kimura T Gotoh M Nakamura Y Arakawa H hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53 Cancer Sci 2003 94 5 431-436 10.1111/j.1349-7006.2003.tb01460.x 12824889
-
(2003)
Cancer Sci
, vol.94
, pp. 431-436
-
-
Kimura, T.1
Gotoh, M.2
Nakamura, Y.3
Arakawa, H.4
-
13
-
-
6944227551
-
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size
-
10.1016/j.cub.2004.09.083 15498494
-
Welcker M Orian A Grim JE Eisenman RN Clurman BE A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size Curr Biol 2004 14 20 1852-1857 10.1016/j.cub.2004.09.083 15498494
-
(2004)
Curr Biol
, vol.14
, Issue.20
, pp. 1852-1857
-
-
Welcker, M.1
Orian, A.2
Grim, J.E.3
Eisenman, R.N.4
Clurman, B.E.5
-
14
-
-
0037102310
-
hCDC4 gene mutations in endometrial cancer
-
12183400
-
Spruck CH Strohmaier H Sangfelt O Muller HM Hubalek M Muller-Holzner E Marth C Widschwendter M Reed SI hCDC4 gene mutations in endometrial cancer Cancer Res 2002 62 16 4535-4539 12183400
-
(2002)
Cancer Res
, vol.62
, Issue.16
, pp. 4535-4539
-
-
Spruck, C.H.1
Strohmaier, H.2
Sangfelt, O.3
Muller, H.M.4
Hubalek, M.5
Muller-Holzner, E.6
Marth, C.7
Widschwendter, M.8
Reed, S.I.9
-
15
-
-
26444480631
-
Mechanisms of tumor suppression by the SCF(Fbw7)
-
16131838
-
Minella AC Clurman BE Mechanisms of tumor suppression by the SCF(Fbw7) Cell Cycle 2005 4 10 1356-1359 16131838
-
(2005)
Cell Cycle
, vol.4
, Issue.10
, pp. 1356-1359
-
-
Minella, A.C.1
Clurman, B.E.2
-
16
-
-
0037462424
-
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase
-
10.1016/S0092-8674(03)00034-5 12553912
-
Orlicky S Tang X Willems A Tyers M Sicheri F Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase Cell 2003 112 2 243-256 10.1016/S0092-8674(03)00034-5 12553912
-
(2003)
Cell
, vol.112
, Issue.2
, pp. 243-256
-
-
Orlicky, S.1
Tang, X.2
Willems, A.3
Tyers, M.4
Sicheri, F.5
-
17
-
-
0029737650
-
Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E
-
452142 8861947
-
Won KA Reed SI Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E Embo J 1996 15 16 4182-4193 452142 8861947
-
(1996)
Embo J
, vol.15
, Issue.16
, pp. 4182-4193
-
-
Won, K.A.1
Reed, S.I.2
-
18
-
-
0029957947
-
Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation
-
8769642
-
Clurman BE Sheaff RJ Thress K Groudine M Roberts JM Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation Genes Dev 1996 10 16 1979-1990 8769642
-
(1996)
Genes Dev
, vol.10
, Issue.16
, pp. 1979-1990
-
-
Clurman, B.E.1
Sheaff, R.J.2
Thress, K.3
Groudine, M.4
Roberts, J.M.5
-
19
-
-
0141591688
-
Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation
-
10.1016/S1097-2765(03)00287-9 14536078
-
Welcker M Singer J Loeb KR Grim J Bloecher A Gurien-West M Clurman BE Roberts JM Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation Mol Cell 2003 12 2 381-392 10.1016/S1097-2765(03)00287-9 14536078
-
(2003)
Mol Cell
, vol.12
, Issue.2
, pp. 381-392
-
-
Welcker, M.1
Singer, J.2
Loeb, K.R.3
Grim, J.4
Bloecher, A.5
Gurien-West, M.6
Clurman, B.E.7
Roberts, J.M.8
-
20
-
-
9644279589
-
Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase
-
10.1074/jbc.M409226200 15364936
-
Ye X Nalepa G Welcker M Kessler BM Spooner E Qin J Elledge SJ Clurman BE Harper JW Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase J Biol Chem 2004 279 48 50110-50119 10.1074/ jbc.M409226200 15364936
-
(2004)
J Biol Chem
, vol.279
, Issue.48
, pp. 50110-50119
-
-
Ye, X.1
Nalepa, G.2
Welcker, M.3
Kessler, B.M.4
Spooner, E.5
Qin, J.6
Elledge, S.J.7
Clurman, B.E.8
Harper, J.W.9
-
21
-
-
14844312051
-
The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4
-
10.1074/jbc.M413377200 15611062
-
Welcker M Clurman BE The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4 J Biol Chem 2005 280 9 7654-7658 10.1074/jbc.M413377200 15611062
-
(2005)
J Biol Chem
, vol.280
, Issue.9
, pp. 7654-7658
-
-
Welcker, M.1
Clurman, B.E.2
-
22
-
-
22244476115
-
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
-
10.1016/j.ccr.2005.06.005 16023596
-
Wei W Jin J Schlisio S Harper JW Kaelin WG Jr. The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase Cancer Cell 2005 8 1 25-33 10.1016/ j.ccr.2005.06.005 16023596
-
(2005)
Cancer Cell
, vol.8
, Issue.1
, pp. 25-33
-
-
Wei, W.1
Jin, J.2
Schlisio, S.3
Harper, J.W.4
Kaelin Jr., W.G.5
-
23
-
-
0034017609
-
Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex
-
14820 10712509
-
Meimoun A Holtzman T Weissman Z McBride HJ Stillman DJ Fink GR Kornitzer D Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex Mol Biol Cell 2000 11 3 915-927 14820 10712509
-
(2000)
Mol Biol Cell
, vol.11
, Issue.3
, pp. 915-927
-
-
Meimoun, A.1
Holtzman, T.2
Weissman, Z.3
McBride, H.J.4
Stillman, D.J.5
Fink, G.R.6
Kornitzer, D.7
-
24
-
-
0030693702
-
Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast
-
316705 9367986
-
Henchoz S Chi Y Catarin B Herskowitz I Deshaies RJ Peter M Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast Genes Dev 1997 11 22 3046-3060 316705 9367986
-
(1997)
Genes Dev
, vol.11
, Issue.22
, pp. 3046-3060
-
-
Henchoz, S.1
Chi, Y.2
Catarin, B.3
Herskowitz, I.4
Deshaies, R.J.5
Peter, M.6
-
25
-
-
0035801406
-
Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis
-
125267 11532947 10.1093/emboj/20.17.4836
-
Perkins G Drury LS Diffley JF Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis Embo J 2001 20 17 4836-4845 125267 11532947 10.1093/emboj/20.17.4836
-
(2001)
Embo J
, vol.20
, Issue.17
, pp. 4836-4845
-
-
Perkins, G.1
Drury, L.S.2
Diffley, J.F.3
-
26
-
-
33644776864
-
Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6
-
1430301 16508019 10.1128/MCB.26.6.2456-2466.2006
-
Jackson LP Reed SI Haase SB Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6 Mol Cell Biol 2006 26 6 2456-2466 1430301 16508019 10.1128/MCB.26.6.2456-2466.2006
-
(2006)
Mol Cell Biol
, vol.26
, Issue.6
, pp. 2456-2466
-
-
Jackson, L.P.1
Reed, S.I.2
Haase, S.B.3
-
27
-
-
0032517963
-
Regulation of the G1 phase of the cell cycle by periodic stabilization and degradation of the p25rum1 CDK inhibitor
-
1170399 9430640 10.1093/emboj/17.2.482
-
Benito J Martin-Castellanos C Moreno S Regulation of the G1 phase of the cell cycle by periodic stabilization and degradation of the p25rum1 CDK inhibitor Embo J 1998 17 2 482-497 1170399 9430640 10.1093/emboj/17.2.482
-
(1998)
Embo J
, vol.17
, Issue.2
, pp. 482-497
-
-
Benito, J.1
Martin-Castellanos, C.2
Moreno, S.3
-
28
-
-
0032440674
-
Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase
-
10.1046/j.1365-2443.1998.00225.x 9990507
-
Kominami K Ochotorena I Toda T Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase Genes Cells 1998 3 11 721-735 10.1046/j.1365-2443.1998.00225.x 9990507
-
(1998)
Genes Cells
, vol.3
, Issue.11
, pp. 721-735
-
-
Kominami, K.1
Ochotorena, I.2
Toda, T.3
-
29
-
-
0034723296
-
Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination
-
10.1074/jbc.275.4.2877 10644755
-
Suzuki H Chiba T Suzuki T Fujita T Ikenoue T Omata M Furuichi K Shikama H Tanaka K Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination J Biol Chem 2000 275 4 2877-2884 10.1074/jbc.275.4.2877 10644755
-
(2000)
J Biol Chem
, vol.275
, Issue.4
, pp. 2877-2884
-
-
Suzuki, H.1
Chiba, T.2
Suzuki, T.3
Fujita, T.4
Ikenoue, T.5
Omata, M.6
Furuichi, K.7
Shikama, H.8
Tanaka, K.9
-
30
-
-
2342526543
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
-
10.1038/ncb1110 15048125
-
Yeh E Cunningham M Arnold H Chasse D Monteith T Ivaldi G Hahn WC Stukenberg PT Shenolikar S Uchida T Counter CM Nevins JR Means AR Sears R A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells Nat Cell Biol 2004 6 4 308-318 10.1038/ncb1110 15048125
-
(2004)
Nat Cell Biol
, vol.6
, Issue.4
, pp. 308-318
-
-
Yeh, E.1
Cunningham, M.2
Arnold, H.3
Chasse, D.4
Monteith, T.5
Ivaldi, G.6
Hahn, W.C.7
Stukenberg, P.T.8
Shenolikar, S.9
Uchida, T.10
Counter, C.M.11
Nevins, J.R.12
Means, A.R.13
Sears, R.14
|