Transforming growth-interacting factor (TGIF) regulates proliferation and differentiation of human myeloid leukemia cells

Molecular Oncology

Volumn 3, Issue 5-6, 2009, Pages 451-463

  Hamid, Rizwan ^a   Brandt, Stephen J ^a,b,c,d  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acute myeloid leukemia; Hematopoiesis; HL60; Leukemia; TGIF

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN EPSILON; RETINOIC ACID; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR RUNX1; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; KNOCKOUT GENE; LEUKEMIA CELL; MYELOPOIESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 70350570381     PISSN: 15747891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molonc.2009.07.004     Document Type: Article

References (54)

1. Bartholin L., Powers S.E., Melhuish T.A., Lasse S., Weinstein M., and Wotton D. TGIF inhibits retinoid signaling. Mol. Cell. Biol. 26 3 (2006) 990-1001
2. Batard P., Monier M.N., Fortunel N., Ducos K., Sansilvestri-Morel P., Phan T., Hatzfeld A., and Hatzfeld J.A. TGF-(beta)1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation. J. Cell. Sci. 113 Pt 3 (2000) 383-390
3. Belloni E., Muenke M., Roessler E., Traverso G., Siegel-Bartelt J., Frumkin A., Mitchell H.F., Donis-Keller H., Helms C., and Hing A.V. Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nat. Genet. 14 3 (1996) 353-356
4. Bernardi R., Papa A., and Pandolfi P.P. Regulation of apoptosis by PML and the PML-NBs. Oncogene 27 48 (2008) 6299-6312
5. Bertolino E., Reimund B., Wildt-Perinic D., and Clerc R.G. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270 52 (1995) 31178-31188
6. Brown S.A., Warburton D., Brown L.Y., Yu C.Y., Roeder E.R., Stengel-Rutkowski S., Hennekam R.C., and Muenke M. Holoprosencephaly due to mutations in ZIC2, a homologue of drosophila odd-paired. Nat. Genet. 20 2 (1998) 180-183
7. Brynczka C., Labhart P., and Merrick B.A. NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation. BMC. Genomics. 8 (2007) 139
8. Collins S.J. The role of retinoids and retinoic acid receptors in normal hematopoiesis. Leukemia 16 10 (2002) 1896-1905
9. de la Cruz J.M., Bamford R.N., Burdine R.D., Roessler E., Barkovich A.J., Donnai D., Schier A.F., and Muenke M. A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Hum. Genet. 110 5 (2002) 422-428
10. Evans T. Regulation of hematopoiesis by retinoid signaling. Exp. Hematol. 33 9 (2005) 1055-1061
11. Ewen M.E., Sluss H.K., Whitehouse L.L., and Livingston D.M. TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74 6 (1993) 1009-1020
12. Faresse N., Colland F., Ferrand N., Prunier C., Bourgeade M.F., and Atfi A. Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling. Embo. J. 27 13 (2008) 1804-1815
13. Gaines P., and Berliner N. Retinoids in myelopoiesis. J. Biol. Regul. Homeost. Agents 17 1 (2003) 46-65
14. Gaines P., and Berliner N. Differentiation and characterization of myeloid cells. Cur. Protocols Immunol. Suppl. 67 (2005)
15. Garbe A., Spyridonidis A., Mobest D., Schmoor C., Mertelsmann R., and Henschler R. Transforming growth factor-beta 1 delays formation of granulocyte-macrophage colony-forming cells, but spares more primitive progenitors during ex vivo expansion of CD34+ haemopoietic progenitor cells. Br. J. Haematol. 99 4 (1997) 951-958
16. Hamid R, Means-Powell J, Martincic D, Kravtsov VD, Shyr Y, Greer JP, Byrne DW, Koury MJ, Brandt SJ. Expression of the TG-Interacting Factor Gene in Blast Cells at Diagnosis Correlates with Patient Survival in Acute Myeloid Leukemia. Blood, Submitted for publication.
17. Hamid R., Patterson J., and Brandt S.J. Genomic structure, alternative splicing and expression of TG-interacting factor, in human myeloid leukemia blasts and cell lines. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms 1779 (2008) 347-355
18. Hobbs S., Jitrapakdee S., and Wallace J.C. Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1alpha promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins. Biochem. Biophys. Res. Commun. 252 2 (1998) 368-372
19. Horie T., Ono K., Kinoshita M., Nishi H., Nagao K., Kawamura T., Abe Y., Wada H., Shimatsu A., Kita T., et al. TG-interacting factor is required for the differentiation of preadipocytes. J. Lipid Res (2008)
20. Iwasaki H., and Akashi K. Myeloid lineage commitment from the hematopoietic stem cell. Immunity 26 6 (2007) 726-740
21. Kastner P., and Chan S. Function of RARalpha during the maturation of neutrophils. Oncogene 20 49 (2001) 7178-7185
22. Kim S.J., and Letterio J. Transforming growth factor-beta signaling in normal and malignant hematopoiesis. Leukemia 17 9 (2003) 1731-1737
23. Klages N., Zufferey R., and Trono D. A stable system for the high-titer production of multiply attenuated lentiviral vectors. Mol. Ther. 2 2 (2000) 170-176
24. Larsson J., and Karlsson S. The role of Smad signaling in hematopoiesis. Oncogene 24 37 (2005) 5676-5692
25. Lawson N.D., and Berliner N. Neutrophil maturation and the role of retinoic acid. Exp. Hematol. 27 9 (1999) 1355-1367
26. Le Cabec V., Calafat J., and Borregaard N. Sorting of the specific granule protein, NGAL, during granulocytic maturation of HL-60 cells. Blood 89 6 (1997) 2113-2121
27. Lee K.Y., and Bae S.C. TGF-beta-dependent cell growth arrest and apoptosis. J. Biochem. Mol. Biol. 35 1 (2002) 47-53
28. Mar L., and Hoodless P.A. Embryonic fibroblasts from mice lacking TGIF were defective in cell cycling. Mol. Cell. Biol. 26 11 (2006) 4302-4310
29. Milne T.A., Hughes C.M., Lloyd R., Yang Z., Rozenblatt-Rosen O., Dou Y., Schnepp R.W., Krankel C., Livolsi V.A., and Gibbs D. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proc. Natl. Acad. Sci. U S A 102 3 (2005) 749-754
30. Ming J.E., Kaupas M.E., Roessler E., Brunner H.G., Golabi M., Tekin M., Stratton R.F., Sujansky E., Bale S.J., and Muenke M. Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly. Hum. Genet. 110 4 (2002) 297-301
31. Moffat J., Grueneberg D.A., Yang X., Kim S.Y., Kloepfer A.M., Hinkle G., Piqani B., Eisenhaure T.M., Luo B., and Grenier J.K. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 124 6 (2006) 1283-1298
32. Mueller B.U., Pabst T., Fos J., Petkovic V., Fey M.F., Asou N., Buergi U., and Tenen D.G. ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression. Blood 107 8 (2006) 3330-3338
33. Naldini L., Blomer U., Gallay P., Ory D., Mulligan R., Gage F.H., Verma I.M., and Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272 5259 (1996) 263-267
34. Orimo A., Gupta P.B., Sgroi D.C., Arenzana-Seisdedos F., Delaunay T., Naeem R., Carey V.J., Richardson A.L., and Weinberg R.A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121 3 (2005) 335-348
35. Phillips R.L., Ernst R.E., Brunk B., Ivanova N., Mahan M.A., Deanehan J.K., Moore K.A., Overton G.C., and Lemischka I.R. The genetic program of hematopoietic stem cells. Science 288 5471 (2000) 1635-1640
36. Purton E.L. Roles of retinoids and retinoic Acid receptors in the regulation of hematopoietic stem cell self-renewal and differentiation. PPAR Res 2007 (2007) 87934
37. Roessler E., Du Y.Z., Mullor J.L., Casas E., Allen W.P., Gillessen-Kaesbach G., Roeder E.R., Ming J.E., Ruiz i Altaba A., and Muenke M. Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features. Proc. Natl. Acad. Sci. U S A 100 23 (2003) 13424-13429
38. Rosenbauer F., and Tenen D.G. Transcription factors in myeloid development: balancing differentiation with transformation. Nat. Rev. Immunol. 7 2 (2007) 105-117
39. Ruegemer J.J., Ho S.N., Augustine J.A., Schlager J.W., Bell M.P., McKean D.J., and Abraham R.T. Regulatory effects of transforming growth factor-beta on IL-2- and IL-4-dependent T cell-cycle progression. J. Immunol. 144 5 (1990) 1767-1776
40. Sato N., Sanjuan I.M., Heke M., Uchida M., Naef F., and Brivanlou A.H. Molecular signature of human embryonic stem cells and its comparison with the mouse. Dev. Biol. 260 2 (2003) 404-413
41. Seo S.R., Ferrand N., Faresse N., Prunier C., Abecassis L., Pessah M., Bourgeade M.F., and Atfi A. Nuclear retention of the tumor suppressor cPML by the homeodomain protein TGIF restricts TGF-beta signaling. Mol. Cell. 23 4 (2006) 547-559
42. Sitnicka E., Ruscetti F.W., Priestley G.V., Wolf N.S., and Bartelmez S.H. Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells. Blood 88 1 (1996) 82-88
43. Stewart S.A., Dykxhoorn D.M., Palliser D., Mizuno H., Yu E.Y., An D.S., Sabatini D.M., Chen I.S., Hahn W.C., and Sharp P.A. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 9 4 (2003) 493-501
44. Stoeck M., Miescher S., MacDonald H.R., and Von Fliedner V. Transforming growth factors beta slow down cell-cycle progression in a murine interleukin-2 dependent T-cell line. J. Cell. Physiol. 141 1 (1989) 65-73
45. van der Vos K.E., and Coffer P.J. FOXO-binding partners: it takes two to tango. Oncogene 27 16 (2008) 2289-2299
46. Verbeek W., Lekstrom-Himes J., Park D.J., Dang P.M., Vuong P.T., Kawano S., Babior B.M., Xanthopoulos K., and Koeffler H.P. Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils. Blood 94 9 (1999) 3141-3150
47. Wallis D.E., Roessler E., Hehr U., Nanni L., Wiltshire T., Richieri-Costa A., Gillessen-Kaesbach G., Zackai E.H., Rommens J., and Muenke M. Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly. Nat. Genet. 22 2 (1999) 196-198
48. Wotton D., Knoepfler P.S., Laherty C.D., Eisenman R.N., and Massague J. The Smad transcriptional corepressor TGIF recruits mSin3. Cell. Growth. Differ. 12 9 (2001) 457-463
49. Wotton D., Lo R.S., Lee S., and Massague J. A Smad transcriptional corepressor. Cell 97 1 (1999) 29-39
50. Wotton D., Lo R.S., Swaby L.A., and Massague J. Multiple modes of repression by the Smad transcriptional corepressor TGIF. J. Biol. Chem. 274 52 (1999) 37105-37110
51. Yamanaka R., Barlow C., Lekstrom-Himes J., Castilla L.H., Liu P.P., Eckhaus M., Decker T., Wynshaw-Boris A., and Xanthopoulos K.G. Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proc. Natl. Acad. Sci. U S A 94 24 (1997) 13187-13192
52. Zhang H., Li N., Tang Y., Wu W., Zhang Q., and Yu Z. Negative functional interaction of retinoic acid and TGF-beta signaling mediated by TG-interacting factor during chondrogenesis. Cell. Physiol. Biochem. 23 1-3 (2009) 157-164
53. Zhuang Y., Faria T.N., Chambon P., and Gudas L.J. Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells. Mol. Cancer Res. 1 8 (2003) 619-630
54. Zufferey R., Nagy D., Mandel R.J., Naldini L., and Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat. Biotechnol. 15 9 (1997) 871-875