Effects of garlic compounds diallyl sulfide and diallyl bisulfide on arylamine N-acetyltransferase activity in strains of helicobacter pylori from peptic ulcer patients

American Journal of Chinese Medicine

Volumn 26, Issue 3-4, 1998, Pages 353-364

  Chung, J G ^a   Chen, G W ^b   Wu, L T ^a   Chang, H L ^c   Lin, Juang G ^b   Yeh, C C ^b   Wang, T F ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c Department of Urology ^*  (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYL COMPOUND; ALLYL SULFIDE; ANTIINFECTIVE AGENT; ARYLAMINE ACETYLTRANSFERASE; DIALLYL DISULFIDE; DISULFIDE; ENZYME INHIBITOR; SULFIDE; VEGETABLE OIL;

ARTICLE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GARLIC; GROWTH, DEVELOPMENT AND AGING; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; KINETICS; MEDICINAL PLANT; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PEPTIC ULCER;

ALLYL COMPOUNDS; ANTI-BACTERIAL AGENTS; ARYLAMINE N-ACETYLTRANSFERASE; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GARLIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; KINETICS; MICROBIAL SENSITIVITY TESTS; PEPTIC ULCER; PLANT OILS; PLANTS, MEDICINAL; SULFIDES;

EID: 0032247207     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/s0192415x98000397     Document Type: Article

References (43)

1. Barone, F.E., and Tonsey, T.M. Isolation, purification, identification, synthesis and kinetics of activation of the anticandidal component of allium sativum and a hypothesis for its mode of action. Mycologia 69: 793-825, 1977.
2. Belman, S., Solomon, T., Segal, A., Block, E., and Barany, G. Inhibition of soybean lipoxygenase and mouse skin tumor promotion by onion and garlic components J. Biochem. Toxico. 4: 151-160, 1989.
3. Bordia, A. Effect of garlic on human platelet aggregation. Atherosclerosis. 30: 355-360, 1978.
4. Boullin, D.I. Garlic: a platelet inhibitor. Lancet I: 776-777, 1981.
5. Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254, 1976.
6. Cavallito, C.J., Buck, J.S., and Suter, C.M. Allicin. The antibacterial principle of Allium sativum. II: Determination of the chemical structure. J. Am. Chem. Soc. 66: 1952-1954, 1944.
7. Cheon, H.G., Boteju, L.W., and Hanna, P.E. Affinity alkylation of hamster hepatic arylamine N-acetyltransferase: isolation of a modified cysteine residue. Mol. Pharmacol. 42: 82-93, 1992.
8. Cheon, H.G., and Hanna, P.E. Effects of group-selective modification reagents on arylamine N-acetyltransferase activities. Biochem. Pharmacol. 43: 2255-2268, 1992.
9. Chung, J.G., Levy, G.N., and Weber, W.W. Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in tissues of C57BL/6J rapid and B6.A-NatS slow acetylator congenic mice. Drug Metab and Dispos. 21: 1057-1063, 1993.
10. Chung. J.G., Kuo, H.M., Lin.T.H., Ho, C.C., Lee, J.H., Lai, J.M., Levy, G.N., and Weber, W.W. Evidence for arylamine N-acetyltransferase in the nematode Anisakis simplex. Cancer Lett. 106: 1-6, 1996.
11. Chung, J.G., Wang, H.H., Tsou, M. F., Hsien, S.E., Lo, H.H., Yen, Y.S., Chang, S.S., Wu, L.T., and Lee, J.H. Evidence for arylamine N-acetyltransferase in the bacteria Helicobacter pylori. Toxico. Lett. 91: 63-71, 1997a.
12. Chung, J.G., Wang, H.H., Wu, L.T., and Chang, W.C. Emodin affects arylamine N-acetyltransferase activity of the bacteria Helicobacter pylori. Food Chem Toxicol. 35: 1001-1007, 1997b.
13. Cleland, W.W. The statistical analysis of enzyme kinetics data. Adv. Enzymol. 29: 1-30, 1967.
14. Dausch, J.G., and Nixon, D.W. Garlic: a review of its relationship to malignant disease. Preventive Med. 19:346-361,1990.
15. Dixon, M.F. Campylobacterpylori and chronic gastritis. Campylobacterpylori and gastroduodenal disease. Oxford: Blackwell Scientific Publications, 1989, pp. 106-116.
16. Einisto, P., Watanabe, M, Ishidate, M., and Nohmi, T. Mutagenicity of 30 chemicals in S. typhimurium possessing different nitroreductase or O-acetyltranslerase activities, Mutation Res. 259: 95-102, 1991.
17. Ernst, E., Weihmayr, T.H., and Matrai, A. Garlic and blood lipids. Br. Med. J. 291: 139-143, 1985.
18. Evans, D.A.P. N-acetyltranslerase. Phannacol. Ther. 42: 157-234, 1989.
19. Graham, D.Y. Campylobacter pylori and peptic ulcer disease. Gastroenterol. 96 (Suppl): 615-625, 1989.
20. Grant, D.M., Blum, M., Beer, M., and Meyer, U.A. Monomorphic and polymorphic human arylamine N-acetyltransferase: a comparison of liver isoenzymes and expressed products of two cloned genes. Mol. Phannacol. 39: 184-191, 1991.
21. Grant, D.M., Josephy, P.D., and Lord, H. I.. Salmonella typhimurium strains expressing human arylamine N-acetyltranslerase: metabolism and mutagenic activation of aromatic amines. Cancer Res. 52: 3961-3964, 1992.
22. Hentschel, E., Brandslatter, G., Dragosics, B., Hirschi,A.M., Nemec, H., Schütze, K., Taurer, M. and Wurzer, H. Effect of ranitidine and ampicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. N. Engl. J. Med. 328: 308-312, 1993.
23. Ilett, K.K., David, B.M., Detchon, P., Castledon, W.M., and Kwa, R. Acetylator phenotype in colorectal carcinoma. Cancer Res. 47: 1466-1469, 1987.
24. Kato, J., Tominaga, S., and Ito, Y. A prospective .study of atrophie gastritis and stomach cancer risk. Jpn. J. CancerRes. 83: 1137- 1142, 1992.
25. Kinouchi, T., Kataoka, K., Miyanishi, K., Akimoto, S., and Ohnishi, Y. Biological activities of the intestinal microflora in mice treated with antibiotics or untreated and the effects of the microflora on absorption and metabolic activation of orally administrated glutathione conjugates of Kregion epoxides of 1-nitropyrene. Carcinogenesis (Lond.). 14: 869-874, 1993.
26. Lang, N.P., Chu, D.Z.J., Hunter, CF., Kendell, D.C., Flammang, J.J., and Kadlubar, F. Role of aromatic amine acetyltransferase in human colorectal cancer. Arch. ofSurg. 121: 1259-1261, 1987.
27. Lang, N.P., Butter, M.A., Massengill, J., Lawson, M., Stotts, R.C., Hauer-Jensen, M., and Kadluhar, F.F. Rapid metabolic phenotypes for acetyltransferase and cytochrome p4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer of polyps. Cancer Epidemiol. Biomarkers Press 3: 675-682, 1994.
28. Larsen, G.L. Deconjugation of biliary metabolites by microfloral β-glucronidase, sulphatase and cysteine conjugate β-lyase and their subsequent enterohepatic circulation. In. I. Rowland (ed.), Role of Gut Flora in Toxicityand Cancer, London: Academic Press, 1988, pp.79-107.
29. Marshall, B. Campylobacter pylori and gastritis. J. Infect Dis. 153: 650-657,1986.
30. Marshall, B., Goodfwin, C.S., and Warren, J.R. Prospective double-blind trial of duodenal ulcer relapse after eradication of duodenal ulcer relapse after eradication of Campylobacter pylori. Cancer. 2: 1437-1447, 1988.
31. Martell, K.J., Levy, G.N., and Weber, W.W. Cloned mouse N-acetyltransferase: enzymatic properties of expressed Nat-1 and Nat-2 gene products. Mol. Phannacol. 42: 265-272,1992.
32. Miller, E.G., and Miller, J.A. Search for the ultimate chemicals carcinogens and their reaction with cellular macromolecules. Cancer 47: 2327-2345, 1981.
33. Minchin, R.F., Reeves, P.T.,Teitel,C.H, McManus, M.E., Mojarrabi.T., Ilett, K. F., and Kadluhar, F.F. N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferase expressed in COS-1 cells. Biochem Biophys Res Commun. 185: 839-844,1992.
34. Moore, G.S. and Atkins, R.D. The fungicidal and fungistatic effect of an aqueous garlic extract on medically important yeast like fungi. Mycologia 69: 341-348,1977.
35. Ohsako, S., and Deguchi, T. Cloning and expression or cDNAs for polymorphic and monomorphic arylamine NAT from human liver. J. Biol. Chem. 265: 4630-4634, 1990.
36. Sadhana, J., Rao, A.R., Kucheria, K. and BiJani, V. Inhibitory action of garlic oil on the inition of benzo(a)pyrene-induced skin carcinogenesis in mice. Cancer Lett. 40: 193-197, 1988.
37. Seppala, K., Pikkarainen, P., Sipponen, P., Kivilaakso, E., Gormsen, M.H. and the Finnish Gastric Ulcer Study Group. Cure of peptic gastric ulcer associated with eradication of Helicobacter pylori. Gut 36: 834-837, 1995.
38. Sundaram, S.G., and Milner, J.A. Impact of organosulfur components in garlic on canine mammary tumor cells in culture. Cancer Lett. 74: 85-90, 1993.
39. Warren, J.R., and Marshall, B.J. Unidentified curved bacilli on gastric epithelium in active chronic gastritis Lancet 1: 1273-1275,1983.
40. Wang, H.H., and Chung, J.G. Emodin induced cytotoxicity and DNA damage on the Helicobacter pylori. Current Micro. 35: 262-266, 1997.
41. Weber, W.W., and Hein, D.W. N-acetylation pharmacogenetics. Pharmacol Review 37: 25-79, 1985.
42. Weber, W.W. The Acetylator Genes and Drug Response. New York: Oxford University Press, 1987, pp. 21-51.
43. Welch, C., Wuarin, L. and Sidell, N. Antiproliferative effect of the garlic component S-allyl cysteine on human neuroblastoma cells in vitro. Cancer Lett. 63: 211-219,1992.