-
1
-
-
84882903964
-
Left ventricular physiology in hypertension
-
Mosby Elsevier, Philadelphia, PA, Y.H. Lip, J.E. Hall (Eds.)
-
Booz G.W. Left ventricular physiology in hypertension. Comprehensive hypertension 2007, 113-121. Mosby Elsevier, Philadelphia, PA. Y.H. Lip, J.E. Hall (Eds.).
-
(2007)
Comprehensive hypertension
, pp. 113-121
-
-
Booz, G.W.1
-
2
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Heineke J., Molkentin J.D. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006, 7:589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
3
-
-
0038125598
-
Calcium signalling: dynamics, homeostasis and remodelling
-
Berridge M.J., Bootman M.D., Roderick H.L. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 2003, 4:517-529.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 517-529
-
-
Berridge, M.J.1
Bootman, M.D.2
Roderick, H.L.3
-
4
-
-
3242772151
-
Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs
-
Molkentin J.D. Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs. Cardiovasc Res 2004, 63:467-475.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 467-475
-
-
Molkentin, J.D.1
-
5
-
-
62649117270
-
The pathological role of transient receptor potential channels in heart disease
-
Watanabe H., Murakami M., Ohba T., Ono K., Ito H. The pathological role of transient receptor potential channels in heart disease. Circ J 2009, 73:419-427.
-
(2009)
Circ J
, vol.73
, pp. 419-427
-
-
Watanabe, H.1
Murakami, M.2
Ohba, T.3
Ono, K.4
Ito, H.5
-
6
-
-
59649113294
-
Physiology and pathophysiology of canonical transient receptor potential channels
-
Abramowitz J., Birnbaumer L. Physiology and pathophysiology of canonical transient receptor potential channels. FASEB J 2009, 23:297-328.
-
(2009)
FASEB J
, vol.23
, pp. 297-328
-
-
Abramowitz, J.1
Birnbaumer, L.2
-
7
-
-
73049085663
-
Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels
-
Sharif-Naeini R., Folgering J.H., Bichet D., Duprat F., Delmas P., Patel A., et al. Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels. J Mol Cell Cardiol 2010, 48:83-89.
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 83-89
-
-
Sharif-Naeini, R.1
Folgering, J.H.2
Bichet, D.3
Duprat, F.4
Delmas, P.5
Patel, A.6
-
8
-
-
77955473072
-
Canonical TRP channels and mechanotransduction: from physiology to disease states
-
Patel A., Sharif-Naeini R., Folgering J.R., Bichet D., Duprat F., Honoré E. Canonical TRP channels and mechanotransduction: from physiology to disease states. Pflugers Arch 2010, 460:571-581.
-
(2010)
Pflugers Arch
, vol.460
, pp. 571-581
-
-
Patel, A.1
Sharif-Naeini, R.2
Folgering, J.R.3
Bichet, D.4
Duprat, F.5
Honoré, E.6
-
9
-
-
33847372100
-
Upregulation of TRPC1 in the development of cardiac hypertrophy
-
Ohba T., Watanabe H., Murakami M., Takahashi Y., Iino K., Kuromitsu S., et al. Upregulation of TRPC1 in the development of cardiac hypertrophy. J Mol Cell Cardiol 2007, 42:498-507.
-
(2007)
J Mol Cell Cardiol
, vol.42
, pp. 498-507
-
-
Ohba, T.1
Watanabe, H.2
Murakami, M.3
Takahashi, Y.4
Iino, K.5
Kuromitsu, S.6
-
10
-
-
46549085470
-
Stretch-activated channels in the heart: contributions to length-dependence and to cardiomyopathy
-
Ward M.L., Williams I.A., Chu Y., Cooper P.J., Ju Y.K., Allen D.G. Stretch-activated channels in the heart: contributions to length-dependence and to cardiomyopathy. Prog Biophys Mol Biol 2008, 97:232-249.
-
(2008)
Prog Biophys Mol Biol
, vol.97
, pp. 232-249
-
-
Ward, M.L.1
Williams, I.A.2
Chu, Y.3
Cooper, P.J.4
Ju, Y.K.5
Allen, D.G.6
-
11
-
-
72449170101
-
TRPC1 channels are critical for hypertrophic signaling in the heart
-
Seth M., Zhang Z.S., Mao L., Graham V., Burch J., Stiber J., et al. TRPC1 channels are critical for hypertrophic signaling in the heart. Circ Res 2009, 105:1023-1030.
-
(2009)
Circ Res
, vol.105
, pp. 1023-1030
-
-
Seth, M.1
Zhang, Z.S.2
Mao, L.3
Graham, V.4
Burch, J.5
Stiber, J.6
-
13
-
-
33845597014
-
Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling
-
Bush E.W., Hood D.B., Papst P.J., Chapo J.A., Minobe W., Bristow M.R., et al. Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling. J Biol Chem 2006, 281:33487-33496.
-
(2006)
J Biol Chem
, vol.281
, pp. 33487-33496
-
-
Bush, E.W.1
Hood, D.B.2
Papst, P.J.3
Chapo, J.A.4
Minobe, W.5
Bristow, M.R.6
-
14
-
-
77951071535
-
TRPC channels are necessary mediators of pathologic cardiac hypertrophy
-
Wu X., Eder P., Chang B., Molkentin J.D. TRPC channels are necessary mediators of pathologic cardiac hypertrophy. Proc Natl Acad Sci USA 2010, 107:7000-7005.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7000-7005
-
-
Wu, X.1
Eder, P.2
Chang, B.3
Molkentin, J.D.4
-
15
-
-
33751104984
-
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy
-
Onohara N., Nishida M., Inoue R., Kobayashi H., Sumimoto H., Sato Y., et al. TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. EMBO J 2006, 25:5305-5316.
-
(2006)
EMBO J
, vol.25
, pp. 5305-5316
-
-
Onohara, N.1
Nishida, M.2
Inoue, R.3
Kobayashi, H.4
Sumimoto, H.5
Sato, Y.6
-
16
-
-
33845317604
-
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
-
Kuwahara K., Wang Y., McAnally J., Richardson J.A., Bassel-Duby R., Hill J.A., et al. TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J Clin Invest 2006, 116:3114-3126.
-
(2006)
J Clin Invest
, vol.116
, pp. 3114-3126
-
-
Kuwahara, K.1
Wang, Y.2
McAnally, J.3
Richardson, J.A.4
Bassel-Duby, R.5
Hill, J.A.6
-
18
-
-
77949274491
-
Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition
-
Koitabashi N., Aiba T., Hesketh G.G., Rowell J., Zhang M., Takimoto E., et al. Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition. J Mol Cell Cardiol 2010, 48:713-724.
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 713-724
-
-
Koitabashi, N.1
Aiba, T.2
Hesketh, G.G.3
Rowell, J.4
Zhang, M.5
Takimoto, E.6
-
19
-
-
77951232473
-
Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition
-
Nishida M., Watanabe K., Sato Y., Nakaya M., Kitajima N., Ide T., et al. Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition. J Biol Chem 2010, 285:13244-13253.
-
(2010)
J Biol Chem
, vol.285
, pp. 13244-13253
-
-
Nishida, M.1
Watanabe, K.2
Sato, Y.3
Nakaya, M.4
Kitajima, N.5
Ide, T.6
-
20
-
-
77956186884
-
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2
-
Klaiber M., Kruse M., Völker K., Schröter J., Feil R., Freichel M., et al. Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2. Basic Res Cardiol 2010, 105:583-595.
-
(2010)
Basic Res Cardiol
, vol.105
, pp. 583-595
-
-
Klaiber, M.1
Kruse, M.2
Völker, K.3
Schröter, J.4
Feil, R.5
Freichel, M.6
-
21
-
-
77954214838
-
Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart
-
Kinoshita H., Kuwahara K., Nishida M., Jian Z., Rong X., Kiyonaka S., et al. Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Circ Res 2010, 106:1849-1860.
-
(2010)
Circ Res
, vol.106
, pp. 1849-1860
-
-
Kinoshita, H.1
Kuwahara, K.2
Nishida, M.3
Jian, Z.4
Rong, X.5
Kiyonaka, S.6
-
22
-
-
51749116707
-
Roles of TRP channels in the development of cardiac hypertrophy
-
Nishida M., Kurose H. Roles of TRP channels in the development of cardiac hypertrophy. Naunyn Schmiedebergs Arch Pharmacol 2008, 378:395-406.
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.378
, pp. 395-406
-
-
Nishida, M.1
Kurose, H.2
-
24
-
-
58149193222
-
Human Protein Reference Database-2009 update
-
Keshava Prasad T.S., Goel R., Kandasamy K., Keerthikumar S., Kumar S., Mathivanan S., et al. Human Protein Reference Database-2009 update. Nucleic Acids Res 2009, 37(Database issue):D767-72.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.DATABASE ISSUE
-
-
Keshava Prasad, T.S.1
Goel, R.2
Kandasamy, K.3
Keerthikumar, S.4
Kumar, S.5
Mathivanan, S.6
-
25
-
-
14644417845
-
Putting the brakes on cardiac hypertrophy: exploiting the NO-cGMP counter-regulatory system
-
Booz G.W. Putting the brakes on cardiac hypertrophy: exploiting the NO-cGMP counter-regulatory system. Hypertension 2005, 45:341-346.
-
(2005)
Hypertension
, vol.45
, pp. 341-346
-
-
Booz, G.W.1
-
26
-
-
0037143710
-
Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes
-
Fiedler B., Lohmann S.M., Smolenski A., Linnemuller S., Pieske B., Schroder F., et al. Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes. Proc Natl Acad Sci USA 2002, 99:11363-11368.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11363-11368
-
-
Fiedler, B.1
Lohmann, S.M.2
Smolenski, A.3
Linnemuller, S.4
Pieske, B.5
Schroder, F.6
-
29
-
-
77950470200
-
Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model
-
van Oort R.J., Respress J.L., Li N., Reynolds C., De Almeida A.C., Skapura D.G., et al. Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model. Hypertension 2010, 55:932-938.
-
(2010)
Hypertension
, vol.55
, pp. 932-938
-
-
van Oort, R.J.1
Respress, J.L.2
Li, N.3
Reynolds, C.4
De Almeida, A.C.5
Skapura, D.G.6
-
30
-
-
77956179490
-
Lmcd1/Dyxin, a novel Z-disc associated LIM protein, mediates cardiac hypertrophy in vitro and in vivo
-
Frank D., Frauen R., Hanselmann C., Kuhn C., Will R., Gantenberg J., et al. Lmcd1/Dyxin, a novel Z-disc associated LIM protein, mediates cardiac hypertrophy in vitro and in vivo. J Mol Cell Cardiol 2010, 49:673-682.
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 673-682
-
-
Frank, D.1
Frauen, R.2
Hanselmann, C.3
Kuhn, C.4
Will, R.5
Gantenberg, J.6
-
31
-
-
74949112895
-
LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling
-
Bian Z.Y., Huang H., Jiang H., Shen D.F., Yan L., Zhu L.H., et al. LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling. Hypertension 2010, 55:257-263.
-
(2010)
Hypertension
, vol.55
, pp. 257-263
-
-
Bian, Z.Y.1
Huang, H.2
Jiang, H.3
Shen, D.F.4
Yan, L.5
Zhu, L.H.6
-
32
-
-
43249125270
-
Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart
-
Tokudome T., Kishimoto I., Horio T., Arai Y., Schwenke D.O., Hino J., et al. Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart. Circulation 2008, 117:2329-2339.
-
(2008)
Circulation
, vol.117
, pp. 2329-2339
-
-
Tokudome, T.1
Kishimoto, I.2
Horio, T.3
Arai, Y.4
Schwenke, D.O.5
Hino, J.6
-
33
-
-
61749089404
-
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice
-
Takimoto E., Koitabashi N., Hsu S., Ketner E.A., Zhang M., Nagayama T., et al. Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. J Clin Invest 2009, 119:408-420.
-
(2009)
J Clin Invest
, vol.119
, pp. 408-420
-
-
Takimoto, E.1
Koitabashi, N.2
Hsu, S.3
Ketner, E.A.4
Zhang, M.5
Nagayama, T.6
-
34
-
-
64149090178
-
MTOR in growth and protection of hypertrophying myocardium
-
Balasubramanian S., Johnston R.K., Moschella P.C., Mani S.K., Tuxworth W.J., Kuppuswamy D. mTOR in growth and protection of hypertrophying myocardium. Cardiovasc Hematol Agents Med Chem 2009, 7:52-63.
-
(2009)
Cardiovasc Hematol Agents Med Chem
, vol.7
, pp. 52-63
-
-
Balasubramanian, S.1
Johnston, R.K.2
Moschella, P.C.3
Mani, S.K.4
Tuxworth, W.J.5
Kuppuswamy, D.6
-
35
-
-
77949357437
-
Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway
-
Gurusamy N., Lekli I., Mukherjee S., Ray D., Ahsan M.K., Gherghiceanu M., Popescu L.M., Das D.K. Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway. Cardiovasc Res 2010, 86:103-112.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 103-112
-
-
Gurusamy, N.1
Lekli, I.2
Mukherjee, S.3
Ray, D.4
Ahsan, M.K.5
Gherghiceanu, M.6
Popescu, L.M.7
Das, D.K.8
-
36
-
-
77950501014
-
MTOR regulation of autophagy
-
Jung C.H., Ro S.H., Cao J., Otto N.M., Kim D.H. mTOR regulation of autophagy. FEBS Lett 2010, 584:1287-1295.
-
(2010)
FEBS Lett
, vol.584
, pp. 1287-1295
-
-
Jung, C.H.1
Ro, S.H.2
Cao, J.3
Otto, N.M.4
Kim, D.H.5
-
37
-
-
66449083078
-
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
-
Ganley I.G., Lam du H., Wang J., Ding X., Chen S., Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 2009, 284:12297-12305.
-
(2009)
J Biol Chem
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam du, H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
38
-
-
77955290360
-
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice
-
Zhang D., Contu R., Latronico M.V., Zhang J., Rizzi R., Catalucci D., Miyamoto S., Huang K., Ceci M., Gu Y., Dalton N.D., Peterson K.L., Guan K.L., Brown J.H., Chen J., Sonenberg N., Condorelli G. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest 2010, 120:2805-2816.
-
(2010)
J Clin Invest
, vol.120
, pp. 2805-2816
-
-
Zhang, D.1
Contu, R.2
Latronico, M.V.3
Zhang, J.4
Rizzi, R.5
Catalucci, D.6
Miyamoto, S.7
Huang, K.8
Ceci, M.9
Gu, Y.10
Dalton, N.D.11
Peterson, K.L.12
Guan, K.L.13
Brown, J.H.14
Chen, J.15
Sonenberg, N.16
Condorelli, G.17
-
39
-
-
58049177522
-
Integrin stimulation-induced hypertrophy in neonatal rat cardiomyocytes is NO-dependent
-
Umar S., van der Valk E.J., Schalij M.J., van der Wall E.E., Atsma D.E., van der Laarse A. Integrin stimulation-induced hypertrophy in neonatal rat cardiomyocytes is NO-dependent. Mol Cell Biochem 2009, 320:75-84.
-
(2009)
Mol Cell Biochem
, vol.320
, pp. 75-84
-
-
Umar, S.1
van der Valk, E.J.2
Schalij, M.J.3
van der Wall, E.E.4
Atsma, D.E.5
van der Laarse, A.6
-
40
-
-
0037382861
-
Rapamycin attenuates load-induced cardiac hypertrophy in mice
-
Shioi T., McMullen J.R., Tarnavski O., Converso K., Sherwood M.C., Manning W.J., et al. Rapamycin attenuates load-induced cardiac hypertrophy in mice. Circulation 2003, 107:1664-1670.
-
(2003)
Circulation
, vol.107
, pp. 1664-1670
-
-
Shioi, T.1
McMullen, J.R.2
Tarnavski, O.3
Converso, K.4
Sherwood, M.C.5
Manning, W.J.6
-
43
-
-
73349120282
-
Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats
-
Soesanto W., Lin H.Y., Hu E., Lefler S., Litwin S.E., Sena S., et al. Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats. Hypertension 2009, 54:1321-1327.
-
(2009)
Hypertension
, vol.54
, pp. 1321-1327
-
-
Soesanto, W.1
Lin, H.Y.2
Hu, E.3
Lefler, S.4
Litwin, S.E.5
Sena, S.6
-
44
-
-
84884578382
-
Protein phosphorylation
-
Lippincott Williams & Wilkins, Baltimore, Maryland, J.L. Izzo, H.R. Black (Eds.)
-
Booz G.W., Baker K.M. Protein phosphorylation. Hypertension primer: the essentials of high blood pressure 2008, 16-21. Lippincott Williams & Wilkins, Baltimore, Maryland. 4th ed. J.L. Izzo, H.R. Black (Eds.).
-
(2008)
Hypertension primer: the essentials of high blood pressure
, pp. 16-21
-
-
Booz, G.W.1
Baker, K.M.2
-
45
-
-
61949099952
-
Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes
-
Huang B.P., Wang Y., Wang X., Wang Z., Proud C.G. Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes. Am J Physiol Heart Circ Physiol 2009, 296:H505-H514.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Huang, B.P.1
Wang, Y.2
Wang, X.3
Wang, Z.4
Proud, C.G.5
-
46
-
-
77952967459
-
MTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
-
Dowling R.J., Topisirovic I., Alain T., Bidinosti M., Fonseca B.D., Petroulakis E., et al. mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. Science 2010, 328:1172-1176.
-
(2010)
Science
, vol.328
, pp. 1172-1176
-
-
Dowling, R.J.1
Topisirovic, I.2
Alain, T.3
Bidinosti, M.4
Fonseca, B.D.5
Petroulakis, E.6
-
47
-
-
77956362469
-
Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor inhibition
-
Cheng Y., Li H., Ren X., Niu T., Hait W.N., Yang J. Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor inhibition. PLoS ONE 2010, 5:e9715.
-
(2010)
PLoS ONE
, vol.5
-
-
Cheng, Y.1
Li, H.2
Ren, X.3
Niu, T.4
Hait, W.N.5
Yang, J.6
-
48
-
-
77955287244
-
MTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1
-
Kantidakis T., Ramsbottom B.A., Birch J.L., Dowding S.N., White R.J. mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1. Proc Natl Acad Sci USA 2010, 107:11823-11828.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11823-11828
-
-
Kantidakis, T.1
Ramsbottom, B.A.2
Birch, J.L.3
Dowding, S.N.4
White, R.J.5
-
49
-
-
45849115434
-
Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction
-
Xu X., Fassett J., Hu X., Zhu G., Lu Z., Li Y., et al. Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction. Hypertension 2008, 51:1557-1564.
-
(2008)
Hypertension
, vol.51
, pp. 1557-1564
-
-
Xu, X.1
Fassett, J.2
Hu, X.3
Zhu, G.4
Lu, Z.5
Li, Y.6
-
50
-
-
33947574510
-
Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy
-
Li H.L., Yin R., Chen D., Liu D., Wang D., Yang Q., et al. Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy. J Cell Biochem 2007, 100:1086-1099.
-
(2007)
J Cell Biochem
, vol.100
, pp. 1086-1099
-
-
Li, H.L.1
Yin, R.2
Chen, D.3
Liu, D.4
Wang, D.5
Yang, Q.6
-
51
-
-
55949114398
-
AMP activated protein kinase-α2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice
-
Zhang P., Hu X., Xu X., Fassett J., Zhu G., Viollet B., et al. AMP activated protein kinase-α2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice. Hypertension 2008, 52:918-924.
-
(2008)
Hypertension
, vol.52
, pp. 918-924
-
-
Zhang, P.1
Hu, X.2
Xu, X.3
Fassett, J.4
Zhu, G.5
Viollet, B.6
-
52
-
-
66949121471
-
AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease
-
Wong A.K., Howie J., Petrie J.R., Lang C.C. AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease. Clin Sci (Lond) 2009, 116:607-620.
-
(2009)
Clin Sci (Lond)
, vol.116
, pp. 607-620
-
-
Wong, A.K.1
Howie, J.2
Petrie, J.R.3
Lang, C.C.4
-
53
-
-
63849162173
-
AMP-activated protein kinase: a core signalling pathway in the heart
-
Kim A.S., Miller E.J., Young L.H. AMP-activated protein kinase: a core signalling pathway in the heart. Acta Physiol (Oxf) 2009, 196:37-53.
-
(2009)
Acta Physiol (Oxf)
, vol.196
, pp. 37-53
-
-
Kim, A.S.1
Miller, E.J.2
Young, L.H.3
-
54
-
-
70349236112
-
CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes
-
MacDonnell S.M., Weisser-Thomas J., Kubo H., Hanscome M., Liu Q., Jaleel N., et al. CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes. Circ Res 2009, 105:316-325.
-
(2009)
Circ Res
, vol.105
, pp. 316-325
-
-
MacDonnell, S.M.1
Weisser-Thomas, J.2
Kubo, H.3
Hanscome, M.4
Liu, Q.5
Jaleel, N.6
-
55
-
-
72149093508
-
Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction
-
Ikeda Y., Sato K., Pimentel D.R., Sam F., Shaw R.J., Dyck J.R., et al. Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. J Biol Chem 2009, 284:35839-35849.
-
(2009)
J Biol Chem
, vol.284
, pp. 35839-35849
-
-
Ikeda, Y.1
Sato, K.2
Pimentel, D.R.3
Sam, F.4
Shaw, R.J.5
Dyck, J.R.6
-
56
-
-
77953691004
-
Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response
-
Shimano M., Ouchi N., Shibata R., Ohashi K., Pimentel D.R., Murohara T., et al. Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response. J Mol Cell Cardiol 2010, 49:210-220.
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 210-220
-
-
Shimano, M.1
Ouchi, N.2
Shibata, R.3
Ohashi, K.4
Pimentel, D.R.5
Murohara, T.6
-
57
-
-
65249183838
-
Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1
-
Dolinsky V.W., Chan A.Y., Robillard Frayne I., Light P.E., Des Rosiers C., Dyck J.R. Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1. Circulation 2009, 119:1643-1652.
-
(2009)
Circulation
, vol.119
, pp. 1643-1652
-
-
Dolinsky, V.W.1
Chan, A.Y.2
Robillard Frayne, I.3
Light, P.E.4
Des Rosiers, C.5
Dyck, J.R.6
-
58
-
-
77449120223
-
Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway
-
Pillai V.B., Sundaresan N.R., Kim G., Gupta M., Rajamohan S.B., Pillai J.B., et al. Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem 2010, 28:3133-3144.
-
(2010)
J Biol Chem
, vol.28
, pp. 3133-3144
-
-
Pillai, V.B.1
Sundaresan, N.R.2
Kim, G.3
Gupta, M.4
Rajamohan, S.B.5
Pillai, J.B.6
-
60
-
-
54449101472
-
Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways
-
Marin T.M., Clemente C.F., Santos A.M., Picardi P.K., Pascoal V.D., Lopes-Cendes I., et al. Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways. Circ Res 2008, 103:813-824.
-
(2008)
Circ Res
, vol.103
, pp. 813-824
-
-
Marin, T.M.1
Clemente, C.F.2
Santos, A.M.3
Picardi, P.K.4
Pascoal, V.D.5
Lopes-Cendes, I.6
-
61
-
-
67650418364
-
Targeting histone deacetylases for heart failure
-
Bush E.W., McKinsey T.A. Targeting histone deacetylases for heart failure. Expert Opin Ther Targets 2009, 13:767-784.
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 767-784
-
-
Bush, E.W.1
McKinsey, T.A.2
-
62
-
-
0037406061
-
Class II histone deacetylases: versatile regulators
-
Verdin E., Dequiedt F., Kasler H.G. Class II histone deacetylases: versatile regulators. Trends Genet 2003, 19:286-293.
-
(2003)
Trends Genet
, vol.19
, pp. 286-293
-
-
Verdin, E.1
Dequiedt, F.2
Kasler, H.G.3
-
63
-
-
70349251897
-
The role of redox modulation of class II histone deacetylases in mediating pathological cardiac hypertrophy
-
Oka S., Ago T., Kitazono T., Zablocki D., Sadoshima J. The role of redox modulation of class II histone deacetylases in mediating pathological cardiac hypertrophy. J Mol Med 2009, 87:785-791.
-
(2009)
J Mol Med
, vol.87
, pp. 785-791
-
-
Oka, S.1
Ago, T.2
Kitazono, T.3
Zablocki, D.4
Sadoshima, J.5
-
64
-
-
50449087071
-
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes
-
Martini J.S., Raake P., Vinge L.E., DeGeorge B.R., Chuprun J.K., Harris D.M., et al. Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. Proc Natl Acad Sci USA 2008, 105:12457-12462.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 12457-12462
-
-
Martini, J.S.1
Raake, P.2
Vinge, L.E.3
DeGeorge, B.R.4
Chuprun, J.K.5
Harris, D.M.6
-
65
-
-
60549085044
-
The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload
-
Backs J., Backs T., Neef S., Kreusser M.M., Lehmann L.H., Patrick D.M., et al. The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci USA 2009, 106:2342-2347.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2342-2347
-
-
Backs, J.1
Backs, T.2
Neef, S.3
Kreusser, M.M.4
Lehmann, L.H.5
Patrick, D.M.6
-
66
-
-
34147093584
-
Nuclear calcium/calmodulin-dependent protein kinase IIδ preferentially transmits signals to histone deacetylase 4 in cardiac cells
-
Little G.H., Bai Y., Williams T., Poizat C. Nuclear calcium/calmodulin-dependent protein kinase IIδ preferentially transmits signals to histone deacetylase 4 in cardiac cells. J Biol Chem 2007, 282:7219-7231.
-
(2007)
J Biol Chem
, vol.282
, pp. 7219-7231
-
-
Little, G.H.1
Bai, Y.2
Williams, T.3
Poizat, C.4
-
67
-
-
33644641253
-
2+ signaling in cardiac myocyte excitation-transcription coupling
-
2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest 2006, 116:675-682.
-
(2006)
J Clin Invest
, vol.116
, pp. 675-682
-
-
Wu, X.1
Zhang, T.2
Bossuyt, J.3
Li, X.4
McKinsey, T.A.5
Dedman, J.R.6
Olson, E.N.7
Chen, J.8
Brown, J.H.9
Bers, D.M.10
-
68
-
-
74249106877
-
A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase
-
Monovich L., Vega R.B., Meredith E., Miranda K., Rao C., Capparelli M., et al. A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase. FEBS Lett 2010, 584:631-637.
-
(2010)
FEBS Lett
, vol.584
, pp. 631-637
-
-
Monovich, L.1
Vega, R.B.2
Meredith, E.3
Miranda, K.4
Rao, C.5
Capparelli, M.6
-
69
-
-
67349179782
-
Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1
-
Monovich L., Koch K.A., Burgis R., Osimboni E., Mann T., Wall D., et al. Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1. Biochim Biophys Acta 2009, 1789:422-431.
-
(2009)
Biochim Biophys Acta
, vol.1789
, pp. 422-431
-
-
Monovich, L.1
Koch, K.A.2
Burgis, R.3
Osimboni, E.4
Mann, T.5
Wall, D.6
-
70
-
-
76349122643
-
Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors
-
Bush E.W., McKinsey T.A. Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors. Circ Res 2010, 106:272-284.
-
(2010)
Circ Res
, vol.106
, pp. 272-284
-
-
Bush, E.W.1
McKinsey, T.A.2
-
71
-
-
33745173485
-
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy
-
Kong Y., Tannous P., Lu G., Berenji K., Rothermel B.A., Olson E.N., et al. Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation 2006, 113:2579-2588.
-
(2006)
Circulation
, vol.113
, pp. 2579-2588
-
-
Kong, Y.1
Tannous, P.2
Lu, G.3
Berenji, K.4
Rothermel, B.A.5
Olson, E.N.6
-
72
-
-
70449095895
-
Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy
-
Kee H.J., Kook H. Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy. J Mol Cell Cardiol 2009, 47:770-780.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 770-780
-
-
Kee, H.J.1
Kook, H.2
-
73
-
-
33847695362
-
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity
-
Trivedi C.M., Luo Y., Yin Z., Zhang M., Zhu W., Wang T., et al. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat Med 2007, 13:324-331.
-
(2007)
Nat Med
, vol.13
, pp. 324-331
-
-
Trivedi, C.M.1
Luo, Y.2
Yin, Z.3
Zhang, M.4
Zhu, W.5
Wang, T.6
-
74
-
-
58149352444
-
Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy
-
Kee H.J., Eom G.H., Joung H., Shin S., Kim J.R., Cho Y.K., et al. Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy. Circ Res 2008, 103:1259-1269.
-
(2008)
Circ Res
, vol.103
, pp. 1259-1269
-
-
Kee, H.J.1
Eom, G.H.2
Joung, H.3
Shin, S.4
Kim, J.R.5
Cho, Y.K.6
-
75
-
-
77649324591
-
New endogenous regulators of class I histone deacetylases
-
pe1
-
Riccio A. New endogenous regulators of class I histone deacetylases. Sci Signal 2010, pe1.
-
(2010)
Sci Signal
-
-
Riccio, A.1
-
76
-
-
0037162062
-
Lysophospholipids and the cardiovascular system
-
Karliner J.S. Lysophospholipids and the cardiovascular system. Biochim Biophys Acta 2002, 1582:216-221.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 216-221
-
-
Karliner, J.S.1
-
77
-
-
61749094417
-
Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2
-
Glenn D.J., Wang F., Chen S., Nishimoto M., Gardner D.G. Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2. Hypertension 2009, 53:549-555.
-
(2009)
Hypertension
, vol.53
, pp. 549-555
-
-
Glenn, D.J.1
Wang, F.2
Chen, S.3
Nishimoto, M.4
Gardner, D.G.5
-
78
-
-
62349105876
-
Cardiac regulation by phosphoinositide 3-kinases and PTEN
-
Oudit G.Y., Penninger J.M. Cardiac regulation by phosphoinositide 3-kinases and PTEN. Cardiovasc Res 2009, 82:250-260.
-
(2009)
Cardiovasc Res
, vol.82
, pp. 250-260
-
-
Oudit, G.Y.1
Penninger, J.M.2
-
79
-
-
33847081630
-
Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6
-
Kwon Y., Hofmann T., Montell C. Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6. Mol Cell 2007, 25:491-503.
-
(2007)
Mol Cell
, vol.25
, pp. 491-503
-
-
Kwon, Y.1
Hofmann, T.2
Montell, C.3
-
80
-
-
70649114733
-
Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP3 and PIP2 in rabbit coronary artery myocytes
-
Saleh S.N., Albert A.P., Large W.A. Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP3 and PIP2 in rabbit coronary artery myocytes. J Physiol 2009, 587:5361-5375.
-
(2009)
J Physiol
, vol.587
, pp. 5361-5375
-
-
Saleh, S.N.1
Albert, A.P.2
Large, W.A.3
-
81
-
-
79251588033
-
Roles and targets of class I and IIa histone deacetylases in cardiac hypertrophy
-
Kee H.J., Kook H. Roles and targets of class I and IIa histone deacetylases in cardiac hypertrophy. J Biomed Biotechnol 2011, 2011:928326.
-
(2011)
J Biomed Biotechnol
, vol.2011
, pp. 928326
-
-
Kee, H.J.1
Kook, H.2
-
82
-
-
73349084646
-
Inpp 5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness
-
Zhu W., Trivedi C.M., Zhou D., Yuan L., Lu M.M., Epstein J.A. Inpp 5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness. Circ Res 2009, 105:1240-1247.
-
(2009)
Circ Res
, vol.105
, pp. 1240-1247
-
-
Zhu, W.1
Trivedi, C.M.2
Zhou, D.3
Yuan, L.4
Lu, M.M.5
Epstein, J.A.6
-
83
-
-
77951025052
-
Regulation by scaffolding proteins of canonical transient receptor potential channels in striated muscle
-
Sabourin J., Cognard C., Constantin B. Regulation by scaffolding proteins of canonical transient receptor potential channels in striated muscle. J Muscle Res Cell Motil 2009, 30:289-297.
-
(2009)
J Muscle Res Cell Motil
, vol.30
, pp. 289-297
-
-
Sabourin, J.1
Cognard, C.2
Constantin, B.3
-
84
-
-
70450248659
-
Homer and the ryanodine receptor
-
Pouliquin P., Dulhunty A.F. Homer and the ryanodine receptor. Eur Biophys J 2009, 39:91-102.
-
(2009)
Eur Biophys J
, vol.39
, pp. 91-102
-
-
Pouliquin, P.1
Dulhunty, A.F.2
-
85
-
-
27744540144
-
Homer modulates NFAT-dependent signaling during muscle differentiation
-
Stiber J.A., Tabatabaei N., Hawkins A.F., Hawke T., Worley P.F., Williams R.S., Rosenberg P. Homer modulates NFAT-dependent signaling during muscle differentiation. Dev Biol 2005, 287:213-224.
-
(2005)
Dev Biol
, vol.287
, pp. 213-224
-
-
Stiber, J.A.1
Tabatabaei, N.2
Hawkins, A.F.3
Hawke, T.4
Worley, P.F.5
Williams, R.S.6
Rosenberg, P.7
-
86
-
-
60549117111
-
MTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes
-
Vollenbröker B., George B., Wolfgart M., Saleem M.A., Pavenstädt H., Weide T. mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes. Am J Physiol Ren Physiol 2009, 296:F418-F426.
-
(2009)
Am J Physiol Ren Physiol
, vol.296
-
-
Vollenbröker, B.1
George, B.2
Wolfgart, M.3
Saleem, M.A.4
Pavenstädt, H.5
Weide, T.6
-
87
-
-
69249220247
-
Clinical impact of left ventricular hypertrophy and implications for regression
-
Artham S.M., Lavie C.J., Milani R.V., Patel D.A., Verma A., Ventura H.O. Clinical impact of left ventricular hypertrophy and implications for regression. Prog Cardiovasc Dis 2009, 52:153-167.
-
(2009)
Prog Cardiovasc Dis
, vol.52
, pp. 153-167
-
-
Artham, S.M.1
Lavie, C.J.2
Milani, R.V.3
Patel, D.A.4
Verma, A.5
Ventura, H.O.6
-
88
-
-
0036892759
-
Left ventricular mass change during treatment and outcome in patients with essential hypertension
-
Koren M.J., Ulin R.J., Koren A.T., Laragh J.H., Devereux R.B. Left ventricular mass change during treatment and outcome in patients with essential hypertension. Am J Hypertens 2002, 15:1021-1028.
-
(2002)
Am J Hypertens
, vol.15
, pp. 1021-1028
-
-
Koren, M.J.1
Ulin, R.J.2
Koren, A.T.3
Laragh, J.H.4
Devereux, R.B.5
-
89
-
-
0036193935
-
Prevalence of left ventricular hypertrophy in hypertensive patients without and with blood pressure control: data from the PAMELA population. Pressioni Arteriose Monitorate E Loro Associazioni
-
Mancia G., Carugo S., Grassi G., Lanzarotti A., Schiavina R., Cesana G., et al. Prevalence of left ventricular hypertrophy in hypertensive patients without and with blood pressure control: data from the PAMELA population. Pressioni Arteriose Monitorate E Loro Associazioni. Hypertension 2002, 39:744-749.
-
(2002)
Hypertension
, vol.39
, pp. 744-749
-
-
Mancia, G.1
Carugo, S.2
Grassi, G.3
Lanzarotti, A.4
Schiavina, R.5
Cesana, G.6
-
90
-
-
0033675191
-
Left ventricular hypertrophy as a predictor of coronary heart disease mortality and the effect of hypertension
-
Brown D.W., Giles W.H., Croft J.B. Left ventricular hypertrophy as a predictor of coronary heart disease mortality and the effect of hypertension. Am Heart J 2000, 140:848-856.
-
(2000)
Am Heart J
, vol.140
, pp. 848-856
-
-
Brown, D.W.1
Giles, W.H.2
Croft, J.B.3
-
91
-
-
77950463916
-
Reciprocal repression between microRNA-133 and calcineurin regulates cardiac hypertrophy: a novel mechanism for progressive cardiac hypertrophy
-
Dong D.L., Chen C., Huo R., Wang N., Li Z., Tu Y.J., et al. Reciprocal repression between microRNA-133 and calcineurin regulates cardiac hypertrophy: a novel mechanism for progressive cardiac hypertrophy. Hypertension 2010, 55:946-952.
-
(2010)
Hypertension
, vol.55
, pp. 946-952
-
-
Dong, D.L.1
Chen, C.2
Huo, R.3
Wang, N.4
Li, Z.5
Tu, Y.J.6
|