Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model

Hypertension

Volumn 55, Issue 4, 2010, Pages 932-938

  Van Oort, Ralph J ^a   Respress, Jonathan L ^a   Li, Na ^a   Reynolds, Corey ^a   De Almeida, Angela C ^a   Skapura, Darlene G ^a   De Windt, Leon J ^c   Wehrens, Xander H T ^a,b  

^a Department of Molecular Physiology and Biophysics ^*  (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Calcium; Heart failure; Hypertrophy; Ryanodine receptor calcium release channel; Sarcoplasmic reticulum

Indexed keywords

CALCINEURIN; CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; RYANODINE RECEPTOR 2; CALCIUM; RYANODINE RECEPTOR; TRANSCRIPTION FACTOR NFAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BODY WEIGHT; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; EXON; GENE EXPRESSION; GENE MUTATION; HEART HEMODYNAMICS; HEART HYPERTROPHY; HEART STRESS; HEART VENTRICLE OVERLOAD; HEART WEIGHT; HETEROZYGOSITY; HISTOPATHOLOGY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; TRANSCRIPTION INITIATION; ANIMAL; CARDIOMEGALY; CELL SIZE; CYTOLOGY; ECHOCARDIOGRAPHY; GENETICS; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CELL; HYPERTENSION; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CALCINEURIN; CALCIUM; CARDIOMEGALY; CELL SIZE; DISEASE PROGRESSION; ECHOCARDIOGRAPHY; HEART FAILURE; HYPERTENSION; MICE; MYOCARDIUM; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; TIME FACTORS;

EID: 77950470200     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.146449     Document Type: Article

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