Diacylglycerol kinase-ε restores cardiac dysfunction under chronic pressure overload: A new specific regulator of Gαq signaling cascade

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 1, 2008, Pages

  Niizeki, Takeshi ^a   Takeishi, Yasuchika ^b   Kitahara, Tatsuro ^a   Arimoto, Takanori ^a   Ishino, Mitsunori ^a   Bilim, Olga ^a   Suzuki, Satoshi ^a   Sasaki, Toshiki ^a   Nakajima, Osamu ^a   Walsh, Richard A ^c   Goto, Kaoru ^a   Kubota, Isao ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diacylglycerol; Heart failure; Hypertrophy; Protein kinase C

Indexed keywords

CASPASE 3; DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE EPSILON; INOSITOL; PHENYLEPHRINE; PROTEIN KINASE C; UNCLASSIFIED DRUG; DIACYLGLYCEROL; FETOPROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; ISOENZYME; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPC6 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CHRONIC DISEASE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; FEMALE; GENE CONSTRUCT; GENE CONTROL; GENE EXPRESSION; GENE TRANSLOCATION; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SURVIVAL; ANIMAL; CARDIOMEGALY; CHEMICALLY INDUCED DISORDER; DISEASE COURSE; DISEASE MODEL; ENZYMOLOGY; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; LIGATION; METABOLISM; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THORACIC AORTA; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; AORTA, THORACIC; BLOTTING, WESTERN; CARDIOMEGALY; DIACYLGLYCEROL KINASE; DIGLYCERIDES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FETAL PROTEINS; FIBROSIS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEART FAILURE; ISOENZYMES; LIGATION; MICE; MICE, TRANSGENIC; MYOCARDIUM; ORGAN SIZE; PHENYLEPHRINE; PROTEIN KINASE C; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRPC CATION CHANNELS; VENTRICULAR FUNCTION, LEFT;

EID: 49849087015     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00066.2008     Document Type: Article

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