AMP-activated protein kinase pathway: A potential therapeutic target in cardiometabolic disease

Clinical Science

Volumn 116, Issue 8, 2009, Pages 607-620

  Wong, Aaron K F ^a   Howie, Jacqueline ^a   Petrie, John R ^a   Lang, Chim C ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

5 Amino 4 imidazole carboxamideriboside 1 D ribofuranoside (AICAR); AMP activated protein kinase (AMPK); Cardiovascular disease; Insulin resistance; Metformin; Obesity

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; A 769662; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ADIPONECTIN; ATORVASTATIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; EUKARYOTIC ELONGATION FACTOR 2 KINASE; FATTY ACID; FLUINDOSTATIN; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LEPTIN; METFORMIN; MEVINOLIN; PIOGLITAZONE; PROTEIN KINASE; PROTEIN KINASE LKB1; PYRIDONE DERIVATIVE; ROSIGLITAZONE; S6 KINASE; UNCLASSIFIED DRUG; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; DRUG DERIVATIVE; ENZYME ACTIVATOR; RIBONUCLEOTIDE;

CARDIOMYOPATHY; CARDIOVASCULAR DISEASE; CELL GROWTH; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; FATTY ACID OXIDATION; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; HEART ARRHYTHMIA; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HEART MUSCLE ISCHEMIA; HOMEOSTASIS; HUMAN; HYPERCHOLESTEROLEMIA; METABOLIC DISORDER; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW; SINGLE DRUG DOSE; STRESS; DRUG EFFECT; ENZYMOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; CARDIOVASCULAR DISEASES; ENZYME ACTIVATION; ENZYME ACTIVATORS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; METABOLIC SYNDROME X; METFORMIN; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION; THIAZOLIDINEDIONES;

EID: 66949121471     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20080066     Document Type: Review

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