Prediction of oral absorption in humans by experimental immobilized artificial membrane chromatography indices and physicochemical descriptors

International Journal of Pharmaceutics

Volumn 360, Issue 1-2, 2008, Pages 96-106

  Kotecha, Jignesh ^a,b   Shah, Shailesh ^a   Rathod, Ishwarsinh ^a   Subbaiah, Gunta ^b  

^a L M COLLEGE OF PHARMACY   (India)

^b Torrent Research Centre   (India)

Author keywords

Immobilized artificial membrane (IAM); Non linear regression; Oral absorption; Partition coefficients; Physicochemical descriptors

Indexed keywords

ACICLOVIR; AMILORIDE; ATENOLOL; BRETYLIUM; CARBAMAZEPINE; CHLOROTHIAZIDE; CHLORPROMAZINE; CHLORTALIDONE; CIPROFLOXACIN; DEXAMETHASONE; DICLOFENAC; DILTIAZEM; FAMOTIDINE; FUROSEMIDE; GANCICLOVIR; HYDROCHLOROTHIAZIDE; IMIPRAMINE; INDOMETACIN; KETOROLAC; LISINOPRIL; METOLAZONE; NAPROXEN; NORFLOXACIN; PENICILLIN G; PROPRANOLOL; RANITIDINE; TERBUTALINE; TIMOLOL; UNINDEXED DRUG; VERAPAMIL;

ARTICLE; ARTIFICIAL MEMBRANE; CELL MEMBRANE PERMEABILITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMOBILIZED ARTIFICIAL MEMBRANE; LIPOPHILICITY; MOLECULAR WEIGHT; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; PKA; PREDICTION; PRIORITY JOURNAL;

1-OCTANOL; ADMINISTRATION, ORAL; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATA INTERPRETATION, STATISTICAL; FORECASTING; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; MEMBRANES, ARTIFICIAL; NONLINEAR DYNAMICS; PHARMACEUTICAL PREPARATIONS; REGRESSION ANALYSIS; SOLVENTS; SPECTROPHOTOMETRY, ULTRAVIOLET; WATER;

EID: 47249137715     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.04.025     Document Type: Article

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