Chromatographic estimation of drug disposition properties by means of immobilized artificial membranes (IAM) and C18 columns

Journal of Medicinal Chemistry

Volumn 49, Issue 16, 2006, Pages 4861-4870

  Lázaro, Elisabet ^a   Ràfols, Clara ^a   Abraham, Michael H ^b   Rosés, Martí ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 NAPHTHOL; 2 NITROANILINE; 2 NITROANISOLE; 2,3 XYLENOL; 2,4 XYLENOL; 3 NITROANILINE; 4 CHLOROACETANILIDE; 4 CHLOROANILINE; 4 CHLOROPHENOL; 4 NITROANILINE; ACETANILIDE; ACETONITRILE; ACETOPHENONE; ANILINE; BENZALDEHYDE; BENZAMIDE DERIVATIVE; BENZENE; BENZOFURAN; BENZOFURAN DERIVATIVE; BENZONITRILE; BENZOPHENONE; BENZYL BENZOATE; BROMOBENZENE; BUTYLBENZENE; OCTANOL; PHENAZONE; PHENOL DERIVATIVE; PHOSPHOLIPID DERIVATIVE; PINENE; UNCLASSIFIED DRUG; WATER;

ARTICLE; ARTIFICIAL MEMBRANE; BLOOD BRAIN BARRIER; CHROMATOGRAPHIC COLUMN; CHROMATOGRAPHY; CORRELATION ANALYSIS; DEVICE; DRUG DISTRIBUTION; ENERGY; IMMOBILIZATION; IMMOBILIZED ARTIFICIAL MEMBRANE; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; PARAMETER; PARTITION COEFFICIENT; PERFORMANCE; PREDICTION; RELIABILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SKIN PERMEABILITY; SKIN PERMEATION; SOLUTE; SOLVATION; TADPOLE; TADPOLE NARCOSIS; TISSUE BLOOD PARTITION;

ACETONITRILES; ANIMALS; BLOOD-BRAIN BARRIER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INTESTINAL ABSORPTION; MEMBRANES, ARTIFICIAL; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; SILICON DIOXIDE; SKIN ABSORPTION; SOLVENTS; TISSUE DISTRIBUTION; WATER;

EID: 33746897339     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0602108     Document Type: Article

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