pH-Metric logP 10. Determination of liposomal membrane-water partition coefficients of ionizable drugs

Pharmaceutical Research

Volumn 15, Issue 2, 1998, Pages 209-215

  Avdeef, A ^a   Box, K J ^b   Comer, J E A ^b   Hibbert, C ^b   Tam, K Y ^b  

^a PION INC   (United States)

^b Sirius Analytical Instruments Ltd   (United Kingdom)

Author keywords

Drug lipid membrane interaction; Ionizable drug; Liposome; Partition coefficient

Indexed keywords

5 PHENYLPENTANOIC ACID; DICLOFENAC; IBUPROFEN; LIDOCAINE; LIPOSOME; PROCAINE; PROPRANOLOL; TETRACAINE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE; WARFARIN;

ARTICLE; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG TRANSPORT; IONIZATION; LIPID MEMBRANE; LIPOPHILICITY; MEMBRANE TRANSPORT; PARTITION COEFFICIENT; PH; PKA; PRIORITY JOURNAL;

DRUG CARRIERS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MEMBRANES, ARTIFICIAL; PHARMACOKINETICS; WATER;

EID: 0031942688     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011954332221     Document Type: Article

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