Liposome/Water Lipophilicity: Methods, Information Content, and Pharmaceutical Applications

Medicinal Research Reviews

Volumn 24, Issue 3, 2004, Pages 299-324

  Van Balen, Georgette Plemper ^a,c   Martinet, Catherine A Marca ^a   Caron, Giulia ^b   Bouchard, Géraldine ^a   Reist, Marianne ^a   Carrupt, Pierre Main ^a   Fruttero, Roberta ^b   Gasco, Alberto ^b   Testa, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF TURIN   (Italy)

^c Novartis Pharma B V ^*  (Netherlands)

Author keywords

Conformation; Dialysis; Ionization; Lipophilicity; Liposomes; NMR spectroscopy; Partitioning; Phospholipids; Potentiometry; Recognition forces

Indexed keywords

ACRIVASTINE; ALIPHATIC AMINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CETIRIZINE; HYDROXYZINE; LIPOSOME; MEMBRANE PHOSPHOLIPID; PHOSPHATIDYLCHOLINE; SOLVENT; WATER;

ANISOTROPY; DIPOLE; DRUG CONFORMATION; EQUILIBRIUM DIALYSIS; HYDROGEN BOND; HYDROPHILICITY; IONIZATION; LIPOPHILICITY; MEMBRANE TRANSPORT; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; PKA; POTENTIOMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; SURFACE CHARGE;

CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; DIALYSIS; HUMANS; HYDROPHOBICITY; LIPOSOMES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; POTENTIOMETRY; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

EID: 1842863963     PISSN: 01986325     EISSN: None     Source Type: Journal    
DOI: 10.1002/med.10063     Document Type: Review

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