Chromatographic indices determined on an immobilized artificial membrane (IAM) column as descriptors of lipophilic and polar interactions of 4-phenyldihydropyridine calcium-channel blockers with biomembranes

European Journal of Medicinal Chemistry

Volumn 31, Issue 4, 1996, Pages 311-318

  Barbato, F ^a   La Rotonda, M I ^a   Quaglia, F ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

4 phenyldihydropyridine; Biomembrane; HPLC; Immobilized artificial membrane (IAM); log P

Indexed keywords

1,4 DIHYDROPYRIDINE DERIVATIVE; AMLODIPINE; CALCIUM CHANNEL BLOCKING AGENT; FELODIPINE; ISRADIPINE; LACIDIPINE; NICARDIPINE; NIFEDIPINE; NIMODIPINE; NISOLDIPINE; NITRENDIPINE;

ARTICLE; ARTIFICIAL MEMBRANE; DRUG RECEPTOR BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIC STRENGTH; LIPOPHILICITY; MEMBRANE BINDING; MODEL; NONHUMAN; PARTITION COEFFICIENT; TECHNIQUE;

EID: 0029871246     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/0223-5234(96)80368-0     Document Type: Article

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