-
1
-
-
34347220473
-
Defining the Role of mTOR in Cancer
-
DOI 10.1016/j.ccr.2007.05.008, PII S1535610807001511
-
Guertin, D. A. and Sabatini, D. M. (2007) Defining the role of mTOR in cancer. Cancer Cell 12, 9-22 (Pubitemid 47001784)
-
(2007)
Cancer Cell
, vol.12
, Issue.1
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
2
-
-
0036753494
-
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
-
DOI 10.1016/S1097-2765(02)00636-6
-
Loewith, R., Jacinto, E., Wullschleger, S., Lorberg, A., Crespo, J. L., Bonenfant, D., Oppliger, W., Jenoe, P. and Hall, M. N. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol. Cell 10, 457-468 (Pubitemid 35284167)
-
(2002)
Molecular Cell
, vol.10
, Issue.3
, pp. 457-468
-
-
Loewith, R.1
Jacinto, E.2
Wullschleger, S.3
Lorberg, A.4
Crespo, J.L.5
Bonenfant, D.6
Oppliger, W.7
Jenoe, P.8
Hall, M.N.9
-
3
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
DOI 10.1016/S0092-8674(02)00833-4
-
Hara, K., Maruki, Y., Long, X., Yoshino, K., Oshiro, N., Hidayat, S., Tokunaga, C., Avruch, J. and Yonezawa, K. (2002) Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 110, 177-189 (Pubitemid 34876546)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.-I.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
4
-
-
0037178786
-
MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
DOI 10.1016/S0092-8674(02)00808-5
-
Kim, D. H., Sarbassov, D. D., Ali, S. M., King, J. E., Latek, R. R., Erdjument-Bromage, H., Tempst, P. and Sabatini, D. M. (2002) mTOR interacts with raptor to form a nutrient- sensitive complex that signals to the cell growth machinery. Cell 110, 163-175 (Pubitemid 34876545)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim, D.-H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
5
-
-
33947264077
-
PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase
-
DOI 10.1016/j.molcel.2007.03.003, PII S1097276507001487
-
Sancak, Y., Thoreen, C. C., Peterson, T. R., Lindquist, R. A., Kang, S. A., Spooner, E., Carr, S. A. and Sabatini, D. M. (2007) PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol. Cell 25, 903-915 (Pubitemid 46436534)
-
(2007)
Molecular Cell
, vol.25
, Issue.6
, pp. 903-915
-
-
Sancak, Y.1
Thoreen, C.C.2
Peterson, T.R.3
Lindquist, R.A.4
Kang, S.A.5
Spooner, E.6
Carr, S.A.7
Sabatini, D.M.8
-
6
-
-
44449161481
-
The TSC1-TSC2 complex: A molecular switchboard controlling cell growth
-
DOI 10.1042/BJ20080281
-
Huang, J. and Manning, B. D. (2008) The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. Biochem. J. 412, 179-190 (Pubitemid 351758225)
-
(2008)
Biochemical Journal
, vol.412
, Issue.2
, pp. 179-190
-
-
Huang, J.1
Manning, B.D.2
-
7
-
-
34147141941
-
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling
-
DOI 10.1042/BJ20061881
-
Findlay, G. M., Yan, L., Procter, J., Mieulet, V. and Lamb, R. F. (2007) A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling. Biochem. J. 403, 13-20 (Pubitemid 46569862)
-
(2007)
Biochemical Journal
, vol.403
, Issue.1
, pp. 13-20
-
-
Findlay, G.M.1
Yan, L.2
Procter, J.3
Mieulet, V.4
Lamb, R.F.5
-
8
-
-
45849105156
-
The rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
DOI 10.1126/science.1157535
-
Sancak, Y., Peterson, T. R., Shaul, Y. D., Lindquist, R. A., Thoreen, C. C., Bar-Peled, L. and Sabatini, D. M. (2008) The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320, 1496-1501 (Pubitemid 351929429)
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
9
-
-
48649085816
-
Regulation of TORC1 by Rag GTPases in nutrient response
-
Kim, E., Goraksha-Hicks, P., Li, L., Neufeld, T. P. and Guan, K. L. (2008) Regulation of TORC1 by Rag GTPases in nutrient response. Nat. Cell Biol. 10, 935-945
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 935-945
-
-
Kim, E.1
Goraksha-Hicks, P.2
Li, L.3
Neufeld, T.P.4
Guan, K.L.5
-
10
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
DOI 10.1038/ncb1183
-
Jacinto, E., Loewith, R., Schmidt, A., Lin, S., Ruegg, M. A., Hall, A. and Hall, M.N. (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat. Cell Biol. 6, 1122-1128 (Pubitemid 39468014)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.11
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
Hall, M.N.7
-
11
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
DOI 10.1016/j.cub.2004.06.054, PII S0960982204004713
-
Sarbassov, D. D., Ali, S. M., Kim, D. H., Guertin, D. A., Latek, R. R., Erdjument-Bromage, H., Tempst, P. and Sabatini, D. M. (2004) Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14, 1296-1302 (Pubitemid 38991819)
-
(2004)
Current Biology
, vol.14
, Issue.14
, pp. 1296-1302
-
-
Dos D. Sarbassov1
Ali, S.M.2
Kim, D.-H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
12
-
-
33751079895
-
Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
-
DOI 10.1101/gad.1461206
-
Yang, Q., Inoki, K., Ikenoue, T. and Guan, K. L. (2006) Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes Dev. 20, 2820-2832 (Pubitemid 44771744)
-
(2006)
Genes and Development
, vol.20
, Issue.20
, pp. 2820-2832
-
-
Yang, Q.1
Inoki, K.2
Ikenoue, T.3
Guan, K.-L.4
-
13
-
-
33748471980
-
MSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s
-
DOI 10.1016/j.cub.2006.08.001, PII S0960982206019749
-
Frias, M. A., Thoreen, C. C., Jaffe, J. D., Schroder, W., Sculley, T., Carr, S. A. and Sabatini, D. M. (2006) mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr. Biol. 16, 1865-1870 (Pubitemid 44354144)
-
(2006)
Current Biology
, vol.16
, Issue.18
, pp. 1865-1870
-
-
Frias, M.A.1
Thoreen, C.C.2
Jaffe, J.D.3
Schroder, W.4
Sculley, T.5
Carr, S.A.6
Sabatini, D.M.7
-
14
-
-
33749076673
-
SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity
-
DOI 10.1016/j.cell.2006.08.033, PII S0092867406011470
-
Jacinto, E., Facchinetti, V., Liu, D., Soto, N., Wei, S., Jung, S. Y., Huang, Q., Qin, J. and Su, B. (2006) SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127, 125-137 (Pubitemid 44466632)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
Huang, Q.7
Qin, J.8
Su, B.9
-
15
-
-
34347210090
-
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
-
DOI 10.1042/BJ20070540
-
Pearce, L. R., Huang, X., Boudeau, J., Pawlowski, R., Wullschleger, S., Deak, M., Ibrahim, A. F., Gourlay, R., Magnuson, M. A. and Alessi, D. R. (2007) Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Biochem. J. 405, 513-522 (Pubitemid 47172049)
-
(2007)
Biochemical Journal
, vol.405
, Issue.3
, pp. 513-522
-
-
Pearce, L.R.1
Huang, X.2
Boudeau, J.3
Pawlowski, R.4
Wullschleger, S.5
Deak, M.6
Ibrahim, A.F.M.7
Gourlay, R.8
Magnuson, M.A.9
Alessi, D.R.10
-
16
-
-
34548509880
-
PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor β expression and signaling
-
DOI 10.1074/jbc.M704343200
-
Woo, S. Y., Kim, D. H., Jun, C. B., Kim, Y. M., Haar, E. V., Lee, S. I., Hegg, J. W., Bandhakavi, S., Griffin, T. J. and Kim, D. H. (2007) PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor β expression and signaling. J. Biol. Chem. 282, 25604-25612 (Pubitemid 47372842)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.35
, pp. 25604-25612
-
-
Woo, S.-Y.1
Kim, D.-H.2
Jun, C.-B.3
Kim, Y.-M.4
Haar, E.V.5
Lee, S.-I.6
Hegg, J.W.7
Bandhakavi, S.8
Griffin, T.J.9
Kim, D.-H.10
-
17
-
-
43249124698
-
PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis
-
Thedieck, K., Polak, P., Kim, M. L., Molle, K. D., Cohen, A., Jeno, P., Arrieumerlou, C. and Hall, M. N. (2007) PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS ONE 2, e1217
-
(2007)
PLoS ONE
, vol.2
-
-
Thedieck, K.1
Polak, P.2
Kim, M.L.3
Molle, K.D.4
Cohen, A.5
Jeno, P.6
Arrieumerlou, C.7
Hall, M.N.8
-
18
-
-
72949093349
-
The nuts and bolts of AGC protein kinases
-
Pearce, L. R., Komander, D. and Alessi, D. R. (2010) The nuts and bolts of AGC protein kinases. Nat. Rev. 11, 9-22
-
(2010)
Nat. Rev.
, vol.11
, pp. 9-22
-
-
Pearce, L.R.1
Komander, D.2
Alessi, D.R.3
-
19
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
DOI 10.1126/science.1106148
-
Sarbassov, D. D., Guertin, D. A., Ali, S. M. and Sabatini, D. M. (2005) Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307, 1098-1101 (Pubitemid 40262113)
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
20
-
-
58649092475
-
MTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
-
Garcia-Martinez, J. M. and Alessi, D. R. (2008) mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). Biochem. J. 416, 375-385
-
(2008)
Biochem. J.
, vol.416
, pp. 375-385
-
-
Garcia-Martinez, J.M.1
Alessi, D.R.2
-
21
-
-
47949104258
-
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling
-
Ikenoue, T, Inoki, K., Yang, Q., Zhou, X. and Guan, K. L. (2008) Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. EMBO J. 27, 1919-1931
-
(2008)
EMBO J.
, vol.27
, pp. 1919-1931
-
-
Ikenoue, T.1
Inoki, K.2
Yang, Q.3
Zhou, X.4
Guan, K.L.5
-
22
-
-
47949125486
-
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
-
Facchinetti, V., Ouyang, W., Wei, H., Soto, N., Lazorchak, A., Gould, C., Lowry, C., Newton, A. C., Mao, Y., Miao, R. Q. et al. (2008) The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J. 27, 1932-1943
-
(2008)
EMBO J.
, vol.27
, pp. 1932-1943
-
-
Facchinetti, V.1
Ouyang, W.2
Wei, H.3
Soto, N.4
Lazorchak, A.5
Gould, C.6
Lowry, C.7
Newton, A.C.8
Mao, Y.9
Miao, R.Q.10
-
23
-
-
78649712949
-
MTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
-
Oh, W. J., Wu, C. C., Kim, S. J., Facchinetti, V., Julien, L. A., Finlan, M., Roux, P. P., Su, B. and Jacinto, E. (2010) mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. EMBO J. 29, 3939-3951
-
(2010)
EMBO J.
, vol.29
, pp. 3939-3951
-
-
Oh, W.J.1
Wu, C.C.2
Kim, S.J.3
Facchinetti, V.4
Julien, L.A.5
Finlan, M.6
Roux, P.P.7
Su, B.8
Jacinto, E.9
-
24
-
-
33746552164
-
Serum and glucocorticoid-regulated protein kinases: Variations on a theme
-
DOI 10.1002/jcb.20894
-
Tessier, M. and Woodgett, J. R. (2006) Serum and glucocorticoid-regulated protein kinases: variations on a theme. J. Cell. Biochem. 98, 1391-1407 (Pubitemid 44141846)
-
(2006)
Journal of Cellular Biochemistry
, vol.98
, Issue.6
, pp. 1391-1407
-
-
Tessier, M.1
Woodgett, J.R.2
-
25
-
-
0035882103
-
The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB
-
DOI 10.1093/emboj/20.16.4380
-
Biondi, R. M., Kieloch, A., Currie, R. A., Deak, M. and Alessi, D. R. (2001) The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB. EMBO J. 20, 4380-4390 (Pubitemid 32772032)
-
(2001)
EMBO Journal
, vol.20
, Issue.16
, pp. 4380-4390
-
-
Biondi, R.M.1
Kieloch, A.2
Currie, R.A.3
Deak, M.4
Alessi, D.R.5
-
26
-
-
0042967831
-
In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation
-
DOI 10.1093/emboj/cdg407
-
Collins, B. J., Deak, M., Arthur, J. S., Armit, L. J. and Alessi, D. R. (2003) In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation. EMBO J. 22, 4202-4211 (Pubitemid 37021748)
-
(2003)
EMBO Journal
, vol.22
, Issue.16
, pp. 4202-4211
-
-
Collins, B.J.1
Deak, M.2
Arthur, J.S.C.3
Armit, L.J.4
Alessi, D.R.5
-
27
-
-
19944408613
-
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3
-
DOI 10.1042/BJ20041057
-
Murray, J. T., Campbell, D. G., Morrice, N., Auld, G. C., Shpiro, N., Marquez, R., Peggie, M., Bain, J., Bloomberg, G. B., Grahammer, F. et al. (2004) Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Biochem. J. 384, 477-488 (Pubitemid 40018961)
-
(2004)
Biochemical Journal
, vol.384
, Issue.3
, pp. 477-488
-
-
Murray, J.T.1
Campbell, D.G.2
Morrice, N.3
Auld, G.C.4
Shpiro, N.5
Marquez, R.6
Peggie, M.7
Bain, J.8
Bloomberg, G.B.9
Grahammer, F.10
Lang, F.11
Wulff, P.12
Kuhl, D.13
Cohen, P.14
-
28
-
-
0030267396
-
Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination
-
Betz, U. A., Vosshenrich, C. A., Rajewsky, K. and Muller, W. (1996) Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination. Curr. Biol. 6, 1307-1316 (Pubitemid 27004916)
-
(1996)
Current Biology
, vol.6
, Issue.10
, pp. 1307-1316
-
-
Betz, U.A.K.1
Vosshenrich, C.A.J.2
Rajewsky, K.3
Muller, W.4
-
29
-
-
0036200937
-
Akt/protein kinase B promotes organ growth in transgenic mice
-
DOI 10.1128/MCB.22.8.2799-2809.2002
-
Shioi, T., McMullen, J. R., Kang, P. M., Douglas, P. S., Obata, T., Franke, T. F., Cantley, L. C. and Izumo, S. (2002) Akt/protein kinase B promotes organ growth in transgenic mice. Mol. Cell. Biol. 22, 2799-2809 (Pubitemid 34263000)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.8
, pp. 2799-2809
-
-
Shioi, T.1
McMullen, J.R.2
Kang, P.M.3
Douglas, P.S.4
Obata, T.5
Franke, T.F.6
Cantley, L.C.7
Izumo, S.8
-
30
-
-
77953459148
-
Role of the WNK-activated SPAK kinase in regulating blood pressure
-
Rafiqi, F. H., Zuber, A. M., Glover, M., Richardson, C., Fleming, S., Jovanovic, S., Jovanovic, A., O'Shaughnessy, K. M. and Alessi, D .R. (2010) Role of the WNK-activated SPAK kinase in regulating blood pressure. EMBO Mol. Med. 2, 63-75
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 63-75
-
-
Rafiqi, F.H.1
Zuber, A.M.2
Glover, M.3
Richardson, C.4
Fleming, S.5
Jovanovic, S.6
Jovanovic, A.7
O'Shaughnessy, K.M.8
Alessi, D.R.9
-
32
-
-
37549000623
-
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity
-
Kumar, A., Harris, T. E., Keller, S. R., Choi, K. M., Magnuson, M. A. and Lawrence, Jr, J. C. (2008) Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity. Mol. Cell. Biol. 28, 61-70
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 61-70
-
-
Kumar, A.1
Harris, T.E.2
Keller, S.R.3
Choi, K.M.4
Magnuson, M.A.5
Lawrence Jr., J.C.6
-
33
-
-
77953200528
-
Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism
-
Kumar, A., Lawrence, Jr, J. C., Jung, D. Y., Ko, H. J., Keller, S. R., Kim, J. K., Magnuson, M. A. and Harris, T. E. (2010) Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism. Diabetes 59, 1397-1406
-
(2010)
Diabetes
, vol.59
, pp. 1397-1406
-
-
Kumar, A.1
Lawrence Jr., J.C.2
Jung, D.Y.3
Ko, H.J.4
Keller, S.R.5
Kim, J.K.6
Magnuson, M.A.7
Harris, T.E.8
-
34
-
-
67649867447
-
MTOR complex 2 in adipose tissue negatively controls whole-body growth
-
Cybulski, N., Polak, P., Auwerx, J., Ruegg, M.A. and Hall, M. N. (2009) mTOR complex 2 In adipose tissue negatively controls whole-body growth. Proc. Natl. Acad. Sci. U.S.A. 106, 9902-9907
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 9902-9907
-
-
Cybulski, N.1
Polak, P.2
Auwerx, J.3
Ruegg, M.A.4
Hall, M.N.5
-
35
-
-
33646060747
-
Sgk kinases and their role in epithelial transport
-
Lofting, J., Flores, S. Y. and Staub, O. (2006) Sgk kinases and their role in epithelial transport. Annu. Rev. Physiol. 68, 461-490
-
(2006)
Annu. Rev. Physiol.
, vol.68
, pp. 461-490
-
-
Lofting, J.1
Flores, S.Y.2
Staub, O.3
-
36
-
-
18244392958
-
+ channel cell surface expression
-
DOI 10.1093/emboj/20.24.7052
-
+ channel cell surface expression. EMBO J. 20, 7052-7059 (Pubitemid 34062297)
-
(2001)
EMBO Journal
, vol.20
, Issue.24
, pp. 7052-7059
-
-
Debonneville, C.1
Flores, S.Y.2
Kamynina, E.3
Plant, P.J.4
Tauxe, C.5
Thomas, M.A.6
Munster, C.7
Chraibi, A.8
Pratt, J.H.9
Horisberger, J.-D.10
Pearce, D.11
Loffing, J.12
Staub, O.13
-
37
-
-
0037016772
-
+ channel
-
DOI 10.1074/jbc.C100623200
-
Snyder, P. M., Olson, D. R. and Thomas, B. C. (2002) Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel. J. Biol. Chem. 277, 5-8 (Pubitemid 34952020)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.1
, pp. 5-8
-
-
Snyder, P.M.1
Olson, D.R.2
Thomas, B.C.3
-
38
-
-
20144386846
-
14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase
-
Ichimura, T., Yamamura, H., Sasamoto, K., Tominaga, Y., Taoka, M., Kakiuchi, K., Shinkawa, T., Takahashi, N., Shimada, S. and Isobe, T. (2005) 14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase. J. Biol. Chem. 280, 13187-13194
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 13187-13194
-
-
Ichimura, T.1
Yamamura, H.2
Sasamoto, K.3
Tominaga, Y.4
Taoka, M.5
Kakiuchi, K.6
Shinkawa, T.7
Takahashi, N.8
Shimada, S.9
Isobe, T.10
-
39
-
-
0036840696
-
+ retention in the sgkl-knockout mouse
-
DOI 10.1172/JCI200215696
-
+ retention in the sgk1-knockout mouse. J. Clin. Invest. 110, 1263-1268 (Pubitemid 35285752)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.9
, pp. 1263-1268
-
-
Wulff, P.1
Vallon, V.2
Huang, D.Y.3
Volkl, H.4
Yu, F.5
Richter, K.6
Jansen, M.7
Schlunz, M.8
Klingel, K.9
Loffing, J.10
Kauselmann, G.11
Bosl, M.R.12
Lang, F.13
Kuhl, D.14
-
41
-
-
50049083821
-
Role of serum- and glucocorticoid-inducible kinase SGK1 in glucocorticoid regulation of renal electrolyte excretion and blood pressure
-
Boini, K. M., Nammi, S., Grahammer, F., Osswald, H., Kuhl, D. and Lang, F. (2008) Role of serum- and glucocorticoid-inducible kinase SGK1 in glucocorticoid regulation of renal electrolyte excretion and blood pressure. Kidney Blood Pressure Res. 31, 280-289
-
(2008)
Kidney Blood Pressure Res.
, vol.31
, pp. 280-289
-
-
Boini, K.M.1
Nammi, S.2
Grahammer, F.3
Osswald, H.4
Kuhl, D.5
Lang, F.6
-
42
-
-
33646896273
-
Intestinal function of gene-targeted mice lacking serum- and glucocorticoid-inducible kinase 1
-
DOI 10.1152/ajpgi.00231.2005
-
Grahammer, F., Henke, G., Sandu, C., Rexhepaj, R., Hussain, A., Friedrich, B., Risler, T., Metzger, M., Just, L., Skutella, T. et al. (2006) Intestinal function of gene-targeted mice lacking serum- and glucocorticoid-inducible kinase 1. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G1114-G1123 (Pubitemid 43788292)
-
(2006)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.290
, Issue.6
-
-
Grahammer, F.1
Henke, G.2
Sandu, C.3
Rexhepaj, R.4
Hussain, A.5
Friedrich, B.6
Risler, T.7
Metzger, M.8
Just, L.9
Skutella, T.10
Wulff, P.11
Kuhl, D.12
Lang, F.13
-
43
-
-
24744439255
-
Molecular organization of target of rapamycin complex 2
-
DOI 10.1074/jbc.M505553200
-
Wullschleger, S., Loewith, R., Oppliger, W. and Hall, M. N. (2005) Molecular organization of target of rapamycin complex 2. J. Biol. Chem. 280, 30697-30704 (Pubitemid 41291798)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.35
, pp. 30697-30704
-
-
Wullschleger, S.1
Loewith, R.2
Oppliger, W.3
Hall, M.N.4
-
44
-
-
6344265083
-
2 effectors that regulate the actin cytoskeleton
-
DOI 10.1038/sj.emboj.7600384
-
Audhya, A., Loewith, R., Parsons, A. B., Gao, L., Tabuchi, M., Zhou, H., Boone, C., Hall, M. N. and Emr, S. D. (2004) Genome-wide lethality screen identifies new PI4, 5P2 effectors that regulate the actin cytoskeleton. EMBO J. 23, 3747-3757 (Pubitemid 39389706)
-
(2004)
EMBO Journal
, vol.23
, Issue.19
, pp. 3747-3757
-
-
Audhya, A.1
Loewith, R.2
Parsons, A.B.3
Gao, L.4
Tabuchi, M.5
Zhou, H.6
Boone, C.7
Hall, M.N.8
Emr, S.D.9
-
45
-
-
16344385976
-
The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5- bisphosphate and TORC2
-
DOI 10.1091/mbc.E04-07-0564
-
Fadri, M., Daquinag, A., Wang, S., Xue, T. and Kunz, J. (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4, 5-bisphosphate and TORC2. Mol. Biol. Cell 16, 1883-1900 (Pubitemid 40471957)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.4
, pp. 1883-1900
-
-
Fadri, M.1
Daquinag, A.2
Wang, S.3
Xue, T.4
Kunz, J.5
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