The fabric of cancer cell biology - Weaving together the strands

Cancer Cell

Volumn 1, Issue 1, 2002, Pages 3-10

  Klausner, Richard D ^a,b,c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL ACADEMY OF SCIENCES   (United States)

^c White House   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; CARCINOGEN; CYCLIN D1; CYCLIN D2; CYCLIN D3;

ALLELE; CANCER CELL; CANCER GENETICS; CARCINOGENESIS; CELL FUNCTION; CELL LINEAGE; CELL MIGRATION; CELL PROLIFERATION; CELL TYPE; CHROMOSOME MUTATION; CYTOLOGY; EXCISION REPAIR; FUSION GENE; GENE EXPRESSION; GENE FUNCTION; GENOMIC INSTABILITY; GENOTYPE ENVIRONMENT INTERACTION; HEREDITY; HETEROZYGOSITY LOSS; MISMATCH REPAIR; MOLECULAR GENETICS; NONHUMAN; NOTE; PHENOTYPE; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STROMA; ANIMAL; GENETICS; HUMAN; MOLECULAR BIOLOGY; NEOPLASM; REVIEW;

ANIMALS; HUMANS; MOLECULAR BIOLOGY; NEOPLASMS;

EID: 0036463384     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(02)00020-X     Document Type: Note

References (31)

1. Alizadeh, A.A., Eisen, M.B., Davis, R.E., Ma, C., Lossos, I.S., Rosenwald, A., Boldrick, J.C., Sabet, H., Tran, T., Yu, X., et al. (2000). Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403, 503-511.
2. Aplin, A.E., Howe, A., Alahari, S.K., and Juliano, R.L. (1998). Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol. Rev. 50, 197-263.
3. Balmain, A. (2002). Cancer as a complex genetic trait: Tumor susceptibility in humans and mouse models. Cell 108, 145-152.
4. Balmain, A., and Nagase, H. (1998). Cancer resistance genes in mice: models for the study of tumour modifiers. Trends Genet. 14, 139-144.
5. Bishop, J.M., and Weinberg, R.A., eds. (1996). Molecular Oncology (New York: Scientific American, Inc.).
6. Chin, L., Artandi, S.E., Shen, Q., Tam, A., Lee, S.L., Gottlieb, G.J., Greider, C.W., and DePinho, R.A. (1999). p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97, 527-538.
7. Clark, E.A., Golub, T.R., Lander, E.S., and Hynes, R.O. (2000). Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406, 532-535.
8. Cormier, R.T., Bilger, A., Lillich, A.J., Halberg, R.B., Hong, K.H., Gould, K.A., Borenstein, N., Lander, E.S., and Dove, W.F. (2000). The Mom1AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64. Oncogene 19, 3182-3192.
9. Druker, B.J. (2002). Perspectives on the development of a molecularly targeted agent. Cancer Cell 1, this issue, 31-36.
10. Folkman, J. (1997). In Tumor Angiogenesis (Philadelphia: Williams and Wilkins).
11. Gisselsson, D., Jonson, T., Petersen, A., Strombeck, B., Dal Cin, P., Hoglund, M., Mitelman, F., Mertens, F., and Mandahl, N. (2001). Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc. Natl. Acad. Sci. USA 98, 12683-12688.
12. Hahn, W.C., Counter, C.M., Lundberg, A.S., Beijersbergen, R.L., Brooks, M.W., and Weinberg, R.A. (1999). Creation of human tumour cells with defined genetic elements. Nature 400, 464-468.
13. Hanahan, D., and Weinberg, R.A. (2000). The hallmarks of cancer. Cell 100, 57-70.
14. Hendrix, M.J., Seftor, E.A., Meltzer, P.S., Gardner, L.M., Hess, A.R., Kirschmann, D.A., Schatteman, G.C., and Seftor, R.E. (2001). Expression and functional significance of VE-cadherin in aggressive human melanoma cells: role in vasculogenic mimicry. Proc. Natl. Acad. Sci. USA 98, 8018-8023.
15. Hochhaus, A., Kreil, S., Corbin, A., La Rosee, P., Lahaye, T., Berger, U., Cross, N.C., Linkesch, W., Druker, B.J., Hehlmann, R., et al. (2001). Roots of clinical resistance to STI-571 cancer therapy. Science 293, 2163.
16. Hunter, T. (1997). Oncoprotein networks. Cell 88, 333-346.
17. Johnson, J.P. (1991). Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease. Cancer Metastasis Rev. 10, 11-22.
18. Lengauer, C., Kinzler, K.W., and Vogelstein, B. (1998). Genetic instabilities in human cancers. Nature 396, 643-649.
19. Liotta, L.A. (2001). An attractive force in metastasis. Nature 410, 24-25.
20. Mauro, M.J., O'Dwyer, M.E., and Druker, B.J. (2001). ST1571, a tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia: validating the promise of molecularly targeted therapy. Cancer Chemother. Pharmacol. 48 (Suppl 1), S77-S78.
21. Muller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M.E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S.N., et al. (2001). Involvement of chemokine receptors in breast cancer metastasis. Nature 410, 50-56.
22. Olumi, A.F., Grossfeld, G.D., Hayward, S.W., Carroll, P.R., Tlsty, T.D., and Cunha, G.R. (1999). Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res. 59, 5002-5011.
23. Perou, C.M., Sorlie, T., Eisen, M.B., van de Rijn, M., Jeffrey, S.S., Rees, C.A., Pollack, J.R., Ross, D.T., Johnsen, H., Akslen, L.A., et al. (2000). Molecular portraits of human breast tumours. Nature 406, 747-752.
24. Ramaswamy, S., Tamayo, P., Rifkin, R., Mukherjee, S., Yeang, C.H., Angelo, M., Ladd, C., Reich, M., Latulippe, E., Mesirov, J.P., et al. (2001). Multiclass cancer diagnosis using tumor gene expression signatures. Proc. Natl. Acad. Sci. USA
25. Saha, S., Bardelli, A., Buckhaults, P., Velculescu, V.E., Rago, C., Croix, B.S., Romans, K.E., Choti, M.A., Lengauer, C., Kinzler, K.W., and Vogelstein, B. (2001). A phosphatase associated with metastasis of colorectal cancer. Science 294, 1343-1346.
26. Skobe, M., and Fusenig, N.E. (1998). Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc. Natl. Acad. Sci. USA 95, 1050-1055.
27. Snijders, A.M., Nowak, N., Segraves, R., Blackwood, S., Brown, N., Conroy, J., Hamilton, G., Hindle, A.K., Huey, B., Kimura, K., et al. (2001). Assembly of microarrays for genome-wide measurement of DNA copy number. Nat. Genet. 29, 263-264.
28. Stacker, S.A., Caesar, C., Baldwin, M.E., Thornton, G.E., Williams, R.A., Prevo, R., Jackson, D.G., Nishikawa, S., Kubo, H., and Achen, M.G. (2001). VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat. Med. 7, 186-191.
29. Stetler-Stevenson, W.G. (1999). Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention. J. Clin. Invest. 103, 1237-1241.
30. Werb, Z. (1997). ECM and cell surface proteolysis: regulating cellular ecology. Cell 91, 439-442.
31. Yu, Q., Geng, Y., and Sicinski, P. (2001). Specific protection against breast cancers by cyclin D1 ablation. Nature 411, 1017-1021.