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Volumn 109, Issue 2, 2004, Pages 157-162

Mechanisms of genomic instability in human cancer: Insights from studies with human papillomavirus oncoproteins

Author keywords

[No Author keywords available]

Indexed keywords

ONCOGENE PROTEIN E6, HUMAN PAPILLOMAVIRUS TYPE 16; ONCOGENE PROTEIN E7 HUMAN PAPILLOMAVIRUS TYPE 16; ONCOGENE PROTEIN E7-HUMAN PAPILLOMAVIRUS TYPE 16; ONCOPROTEIN; PROTEIN E6; PROTEIN E7;

EID: 1242319406     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.11691     Document Type: Short Survey
Times cited : (313)

References (94)
  • 1
    • 0030577120 scopus 로고    scopus 로고
    • Papillomavirus infections - A major cause of human cancers
    • zur Hausen H. Papillomavirus infections-a major cause of human cancers. Biochim Biophys Acta 1996;1288:F55-78.
    • (1996) Biochim Biophys Acta , vol.1288
    • Zur Hausen, H.1
  • 2
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • Munger K, Howley PM. Human papillomavirus immortalization and transformation functions. Virus Res 2002;89:213-28.
    • (2002) Virus Res , vol.89 , pp. 213-228
    • Munger, K.1    Howley, P.M.2
  • 4
    • 0026322149 scopus 로고
    • Viruses in human cancers
    • zur Hausen H. Viruses in human cancers. Science 1991;254:1167-73.
    • (1991) Science , vol.254 , pp. 1167-1173
    • Zur Hausen, H.1
  • 5
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2002;2:342-50.
    • (2002) Nat Rev Cancer , vol.2 , pp. 342-350
    • Zur Hausen, H.1
  • 6
    • 0026609366 scopus 로고
    • The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells
    • Halbert CL, Demers GW, Galloway DA. The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells. J Virol 1992;66:2125-34.
    • (1992) J Virol , vol.66 , pp. 2125-2134
    • Halbert, C.L.1    Demers, G.W.2    Galloway, D.A.3
  • 7
    • 0024428508 scopus 로고
    • The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
    • Munger K, Phelps WC, Bubb V, Howley PM, Schlegel R. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J Virol 1989;63:4417-21.
    • (1989) J Virol , vol.63 , pp. 4417-4421
    • Munger, K.1    Phelps, W.C.2    Bubb, V.3    Howley, P.M.4    Schlegel, R.5
  • 10
    • 0024513575 scopus 로고
    • Induction of human cervical squamous cell carcinoma by sequential transfection with human papillomavirus type 16 DNA and viral Harvey ras
    • DiPaolo JA, Woodworth CD, Popescu NC, Notario V, Doninger J. Induction of human cervical squamous cell carcinoma by sequential transfection with human papillomavirus type 16 DNA and viral Harvey ras. Oncogene 1989;4:395-99.
    • (1989) Oncogene , vol.4 , pp. 395-399
    • DiPaolo, J.A.1    Woodworth, C.D.2    Popescu, N.C.3    Notario, V.4    Doninger, J.5
  • 11
    • 0033497345 scopus 로고    scopus 로고
    • Immortalization of human cells and their malignant conversion by high risk human papillomavirus genotypes
    • zur Hausen H. Immortalization of human cells and their malignant conversion by high risk human papillomavirus genotypes. Semin Cancer Biol 1999;9:405-11.
    • (1999) Semin Cancer Biol , vol.9 , pp. 405-411
    • Zur Hausen, H.1
  • 12
    • 0036463384 scopus 로고    scopus 로고
    • The fabric of cancer cell biology - Weaving together the strands
    • Klausner RD. The fabric of cancer cell biology-weaving together the strands. Cancer Cell 2002;1:3-10.
    • (2002) Cancer Cell , vol.1 , pp. 3-10
    • Klausner, R.D.1
  • 13
    • 10744229405 scopus 로고    scopus 로고
    • Centrosomes, genomic instability, and cervical carcinogenesis
    • Duensing S, Münger K. Centrosomes, genomic instability, and cervical carcinogenesis. Crit Rev Eukaryot Gene Expr 2003;13:9-23.
    • (2003) Crit Rev Eukaryot Gene Expr , vol.13 , pp. 9-23
    • Duensing, S.1    Münger, K.2
  • 15
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 16
    • 0001414735 scopus 로고    scopus 로고
    • Papillomaviruses and their replication
    • Knipe DM, Howley PM, eds. Philadelphia: Lippincott Williams & Wilkins
    • Howley PM, Lowy DR. Papillomaviruses and their replication. In: Knipe DM, Howley PM, eds. Field's virology, vol. 2. Philadelphia: Lippincott Williams & Wilkins, 2001. 2197-229.
    • (2001) Field's Virology , vol.2 , pp. 2197-229
    • Howley, P.M.1    Lowy, D.R.2
  • 18
    • 0030827303 scopus 로고    scopus 로고
    • Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein
    • Funk JO, Waga S, Harry JB, Espling E, Stillman B, Galloway DA. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev 1997;11:2090-100.
    • (1997) Genes Dev , vol.11 , pp. 2090-2100
    • Funk, J.O.1    Waga, S.2    Harry, J.B.3    Espling, E.4    Stillman, B.5    Galloway, D.A.6
  • 19
    • 0030756473 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2
    • Jones DL, Alani RM, Munger K. The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2. Genes Dev 1997;11:2101-11.
    • (1997) Genes Dev , vol.11 , pp. 2101-2111
    • Jones, D.L.1    Alani, R.M.2    Munger, K.3
  • 21
    • 0032505579 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins alter differentiation-dependent cell cycle exit on suspension in semisolid medium
    • Ruesch MN, Laimins LA. Human papillomavirus oncoproteins alter differentiation-dependent cell cycle exit on suspension in semisolid medium. Virology 1998;250:19-29.
    • (1998) Virology , vol.250 , pp. 19-29
    • Ruesch, M.N.1    Laimins, L.A.2
  • 22
    • 0029134617 scopus 로고
    • Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation
    • Zerfass K, Schulze A, Spitkovsky D, Friedman V, Henglein B, Jansen-Durr P. Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation. J Virol 1995;69:6389-99.
    • (1995) J Virol , vol.69 , pp. 6389-6399
    • Zerfass, K.1    Schulze, A.2    Spitkovsky, D.3    Friedman, V.4    Henglein, B.5    Jansen-Durr, P.6
  • 23
    • 0031594586 scopus 로고    scopus 로고
    • Disruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin E
    • Martin LG, Demers GW, Galloway DA. Disruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin E. J Virol 1998;72:975-85.
    • (1998) J Virol , vol.72 , pp. 975-985
    • Martin, L.G.1    Demers, G.W.2    Galloway, D.A.3
  • 24
    • 0031887359 scopus 로고    scopus 로고
    • Anchorage-independent transcription of the cyclin A gene induced by the E7 oncoprotein of human papillomavirus type 16
    • Schulze A, Mannhardt B, Zerfass-Thome K, Zwerschke W, Jansen-Durr P. Anchorage-independent transcription of the cyclin A gene induced by the E7 oncoprotein of human papillomavirus type 16. J Virol 1998;72:2323-34.
    • (1998) J Virol , vol.72 , pp. 2323-2334
    • Schulze, A.1    Mannhardt, B.2    Zerfass-Thome, K.3    Zwerschke, W.4    Jansen-Durr, P.5
  • 25
    • 0032190833 scopus 로고    scopus 로고
    • Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression
    • Bates S, Ryan KM, Phillips AC, Vousden KH. Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression. Oncogene 1998;17:1691-703.
    • (1998) Oncogene , vol.17 , pp. 1691-1703
    • Bates, S.1    Ryan, K.M.2    Phillips, A.C.3    Vousden, K.H.4
  • 26
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993;75:495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 27
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 1990;63:1129-36.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 28
    • 0030008177 scopus 로고    scopus 로고
    • Telomerase activation by the E6 gene product of human papillomavirus type 16
    • Klingelhutz AJ, Foster SA, McDougall JK. Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 1996; 380:79-82.
    • (1996) Nature , vol.380 , pp. 79-82
    • Klingelhutz, A.J.1    Foster, S.A.2    McDougall, J.K.3
  • 29
    • 0026452949 scopus 로고
    • Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
    • Hartwell L. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 1992;71:543-46.
    • (1992) Cell , vol.71 , pp. 543-546
    • Hartwell, L.1
  • 30
    • 0028331229 scopus 로고
    • Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
    • White AE, Livanos EM, Tlsty TD. Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev 1994;8:666-77.
    • (1994) Genes Dev , vol.8 , pp. 666-677
    • White, A.E.1    Livanos, E.M.2    Tlsty, T.D.3
  • 31
    • 0025850353 scopus 로고
    • Induction of chromosome abnormalities in mouse and human epidermal keratinocytes by the human papillomavirus type 16 E7 oncogene
    • Hashida T, Yasumoto S. Induction of chromosome abnormalities in mouse and human epidermal keratinocytes by the human papillomavirus type 16 E7 oncogene. J Gen Virol 1991;72:1569-77.
    • (1991) J Gen Virol , vol.72 , pp. 1569-1577
    • Hashida, T.1    Yasumoto, S.2
  • 32
    • 0021342335 scopus 로고
    • Human papillomavirus type 16 and early cervical neoplasia
    • Crum CP, Ikenberg H, Richart RM, Gissman L. Human papillomavirus type 16 and early cervical neoplasia. N Engl J Med 1984;310:880-3.
    • (1984) N Engl J Med , vol.310 , pp. 880-883
    • Crum, C.P.1    Ikenberg, H.2    Richart, R.M.3    Gissman, L.4
  • 33
    • 0034730196 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
    • Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S, Gonzalez S, Crum CP, Munger K. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc Natl Acad Sci USA 2000;97:10002-7.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10002-10007
    • Duensing, S.1    Lee, L.Y.2    Duensing, A.3    Basile, J.4    Piboonniyom, S.5    Gonzalez, S.6    Crum, C.P.7    Munger, K.8
  • 36
    • 0035873385 scopus 로고    scopus 로고
    • "It takes two to tango": Understanding how centrosome duplication is regulated throughout the cell cycle
    • Hinchcliffe EH, Sluder G. "It takes two to tango": understanding how centrosome duplication is regulated throughout the cell cycle. Genes Dev 2001;15:1167-81.
    • (2001) Genes Dev , vol.15 , pp. 1167-1181
    • Hinchcliffe, E.H.1    Sluder, G.2
  • 37
    • 0033525007 scopus 로고    scopus 로고
    • Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts
    • Hinchcliffe EH, Li C, Thompson EA, Maller JL, Sluder G. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts. Science 1999;283:851-4.
    • (1999) Science , vol.283 , pp. 851-854
    • Hinchcliffe, E.H.1    Li, C.2    Thompson, E.A.3    Maller, J.L.4    Sluder, G.5
  • 38
    • 0033145516 scopus 로고    scopus 로고
    • Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
    • Meraldi P, Lukas J, Fry AM, Bartek J, Nigg EA. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat Cell Biol 1999;1:88-93.
    • (1999) Nat Cell Biol , vol.1 , pp. 88-93
    • Meraldi, P.1    Lukas, J.2    Fry, A.M.3    Bartek, J.4    Nigg, E.A.5
  • 39
    • 0033594469 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells
    • Matsumoto Y, Hayashi K, Nishida E. Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells. Curr Biol 1999;9:429-32.
    • (1999) Curr Biol , vol.9 , pp. 429-432
    • Matsumoto, Y.1    Hayashi, K.2    Nishida, E.3
  • 40
    • 0033055061 scopus 로고    scopus 로고
    • Cyclin-dependent kinase control of centrosome duplication
    • Lacey KR, Jackson PK, Stearns T. Cyclin-dependent kinase control of centrosome duplication. Proc Natl Acad Sci USA 1999;96:2817-22.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2817-2822
    • Lacey, K.R.1    Jackson, P.K.2    Stearns, T.3
  • 41
    • 0035866774 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 oncoprotein-induced abnormal centrosome synthesis is an early event in the evolving malignant phenotype
    • Duensing S, Duensing A, Crum CP, Munger K. Human papillomavirus type 16 E7 oncoprotein-induced abnormal centrosome synthesis is an early event in the evolving malignant phenotype. Cancer Res 2001;61:2356-60.
    • (2001) Cancer Res , vol.61 , pp. 2356-2360
    • Duensing, S.1    Duensing, A.2    Crum, C.P.3    Munger, K.4
  • 43
    • 0036831681 scopus 로고    scopus 로고
    • Centrosome aberrations: Cause or consequence of cancer progression?
    • Nigg EA. Centrosome aberrations: cause or consequence of cancer progression? Nat Rev Cancer 2002;2:1-11.
    • (2002) Nat Rev Cancer , vol.2 , pp. 1-11
    • Nigg, E.A.1
  • 44
    • 0031586324 scopus 로고    scopus 로고
    • Genomic instability and telomerase activity in human bronchial epithelial cells during immortalization by human papillomavirus-16 E6 and E7 genes
    • Coursen JD, Bennett WP, Gollahon L, Shay JW, Harris CC. Genomic instability and telomerase activity in human bronchial epithelial cells during immortalization by human papillomavirus-16 E6 and E7 genes. Exp Cell Res 1997;235:245-53.
    • (1997) Exp Cell Res , vol.235 , pp. 245-253
    • Coursen, J.D.1    Bennett, W.P.2    Gollahon, L.3    Shay, J.W.4    Harris, C.C.5
  • 45
    • 0036897282 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability
    • Duensing S, Münger K. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res 2002;62:7075-82.
    • (2002) Cancer Res , vol.62 , pp. 7075-7082
    • Duensing, S.1    Münger, K.2
  • 48
    • 0242300161 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members
    • Duensing S, Münger K. Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members. J Virol 2003;77:12331-5.
    • (2003) J Virol , vol.77 , pp. 12331-12335
    • Duensing, S.1    Münger, K.2
  • 50
    • 0041327168 scopus 로고    scopus 로고
    • Proliferation of cancer cells despite cdk2 inhibition
    • Tetsu O, McCormick F. Proliferation of cancer cells despite cdk2 inhibition. Cancer Cell 2003;3:233-45.
    • (2003) Cancer Cell , vol.3 , pp. 233-245
    • Tetsu, O.1    McCormick, F.2
  • 52
    • 0037127006 scopus 로고    scopus 로고
    • Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts
    • Matsumoto Y, Maller JL. Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts. Science 2002;295:499-502.
    • (2002) Science , vol.295 , pp. 499-502
    • Matsumoto, Y.1    Maller, J.L.2
  • 53
    • 0038142191 scopus 로고    scopus 로고
    • Centrosome number is controlled by a centrosome-intrinsic block to reduplication
    • Wong C, Stearns T. Centrosome number is controlled by a centrosome-intrinsic block to reduplication. Nat Cell Biol 2003;5:539-44.
    • (2003) Nat Cell Biol , vol.5 , pp. 539-544
    • Wong, C.1    Stearns, T.2
  • 54
    • 0034910012 scopus 로고    scopus 로고
    • Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes
    • Duensing S, Duensing A, Flores ER, Do A, Lambert PF, Munger K. Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes. J Virol 2001;75:7712-6.
    • (2001) J Virol , vol.75 , pp. 7712-7716
    • Duensing, S.1    Duensing, A.2    Flores, E.R.3    Do, A.4    Lambert, P.F.5    Munger, K.6
  • 55
    • 0042440926 scopus 로고    scopus 로고
    • Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis
    • Riley RR, Duensing S, Brake T, Munger K, Lambert PF, Arbeit JM. Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Res 2003;63:4862-71.
    • (2003) Cancer Res , vol.63 , pp. 4862-4871
    • Riley, R.R.1    Duensing, S.2    Brake, T.3    Munger, K.4    Lambert, P.F.5    Arbeit, J.M.6
  • 56
    • 0037048297 scopus 로고    scopus 로고
    • Human papillomaviruses and centrosome duplication errors: Modeling the origins of genomic instability
    • Duensing S, Munger K. Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene 2002;21:6241-8.
    • (2002) Oncogene , vol.21 , pp. 6241-6248
    • Duensing, S.1    Munger, K.2
  • 57
    • 0035051849 scopus 로고    scopus 로고
    • Human papillomavirus infection, centrosome aberration, and genetic stability in cervical lesions
    • Skyldberg B, Fujioka K, Hellstrom AC, Sylven L, Moberger B, Auer G. Human papillomavirus infection, centrosome aberration, and genetic stability in cervical lesions. Mod Pathol 2001;14:279-84.
    • (2001) Mod Pathol , vol.14 , pp. 279-284
    • Skyldberg, B.1    Fujioka, K.2    Hellstrom, A.C.3    Sylven, L.4    Moberger, B.5    Auer, G.6
  • 58
    • 1242281345 scopus 로고    scopus 로고
    • Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma
    • Duensing S, Lee BH, Dal Cin P, Münger K. Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Mol Cancer 2003;2:30.
    • (2003) Mol Cancer , vol.2 , pp. 30
    • Duensing, S.1    Lee, B.H.2    Dal Cin, P.3    Münger, K.4
  • 59
    • 0031930282 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint
    • Thomas JT, Laimins LA. Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint. J Virol 1998;72:1131-7.
    • (1998) J Virol , vol.72 , pp. 1131-1137
    • Thomas, J.T.1    Laimins, L.A.2
  • 60
    • 0031577693 scopus 로고    scopus 로고
    • The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints
    • Thompson DA, Belinsky G, Chang TH, Jones DL, Schlegel R, Munger K. The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints. Oncogene 1997;15:3025-35.
    • (1997) Oncogene , vol.15 , pp. 3025-3035
    • Thompson, D.A.1    Belinsky, G.2    Chang, T.H.3    Jones, D.L.4    Schlegel, R.5    Munger, K.6
  • 61
    • 0031931414 scopus 로고    scopus 로고
    • Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
    • Lanni JS, Jacks T. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol 1998;18: 1055-64.
    • (1998) Mol Cell Biol , vol.18 , pp. 1055-1064
    • Lanni, J.S.1    Jacks, T.2
  • 62
    • 0037084163 scopus 로고    scopus 로고
    • Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells
    • Meraldi P, Honda R, Nigg EA. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J 2002;21:483-92.
    • (2002) EMBO J , vol.21 , pp. 483-492
    • Meraldi, P.1    Honda, R.2    Nigg, E.A.3
  • 63
    • 0030880321 scopus 로고    scopus 로고
    • Basal cell tetrasomy in low-grade cervical squamous intraepithelial lesions infected with high-risk human papillomaviruses
    • Southern SA, Evans MF, Herrington CS. Basal cell tetrasomy in low-grade cervical squamous intraepithelial lesions infected with high-risk human papillomaviruses. Cancer Res 1997;57:4210-3.
    • (1997) Cancer Res , vol.57 , pp. 4210-4213
    • Southern, S.A.1    Evans, M.F.2    Herrington, C.S.3
  • 64
    • 0037168189 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 oncogene induces premature mitotic chromosome segregation
    • Plug-Demaggio AW, McDougall JK. The human papillomavirus type 16 E6 oncogene induces premature mitotic chromosome segregation. Oncogene 2002;21:7507-13.
    • (2002) Oncogene , vol.21 , pp. 7507-7513
    • Plug-Demaggio, A.W.1    McDougall, J.K.2
  • 65
    • 0030991734 scopus 로고    scopus 로고
    • Specific chromosomal imbalances in human papillomavirus-transfected cells during progression toward immortality
    • Solinas-Toldo S, Dürst M, Lichter P. Specific chromosomal imbalances in human papillomavirus-transfected cells during progression toward immortality. Proc Natl Acad Sci USA 1997;94:3854-9.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3854-3859
    • Solinas-Toldo, S.1    Dürst, M.2    Lichter, P.3
  • 66
    • 0031010967 scopus 로고    scopus 로고
    • HPV-16 oncogenes E6 and E7 are mutagenic in normal human oral keratinocytes
    • Liu X, Han S, Baluda MA, Park NH. HPV-16 oncogenes E6 and E7 are mutagenic in normal human oral keratinocytes. Oncogene 1997; 14:2347-53.
    • (1997) Oncogene , vol.14 , pp. 2347-2353
    • Liu, X.1    Han, S.2    Baluda, M.A.3    Park, N.H.4
  • 67
    • 0032478282 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 oncogenes abrogate radioaction-induced DNA damage response in vivo through p63-dependent and p53-independent mechanisms
    • Song S, Gulliver GA, Lambert PF. Human papillomavirus type 16 E6 and E7 oncogenes abrogate radioaction-induced DNA damage response in vivo through p63-dependent and p53-independent mechanisms. Proc Natl Acad Sci USA 1998;95:2290-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2290-2295
    • Song, S.1    Gulliver, G.A.2    Lambert, P.F.3
  • 69
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000;10:886-95.
    • (2000) Curr Biol , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 70
    • 0029809740 scopus 로고    scopus 로고
    • Expression of HPV16 E6 or E7 increases integration of foreign DNA
    • Kessis TD, Connolly DC, Hedrick L, Cho KR. Expression of HPV16 E6 or E7 increases integration of foreign DNA. Oncogene 1996;13: 427-31.
    • (1996) Oncogene , vol.13 , pp. 427-431
    • Kessis, T.D.1    Connolly, D.C.2    Hedrick, L.3    Cho, K.R.4
  • 71
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998;396:643-9.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 74
    • 0037114361 scopus 로고    scopus 로고
    • The role of human papillomavirus oncoproteins E6 and E7 in apoptosis
    • Finzer P, Aguilar-Lemarroy A, Rösl F. The role of human papillomavirus oncoproteins E6 and E7 in apoptosis. Cancer Lett 2002; 188:15-24.
    • (2002) Cancer Lett , vol.188 , pp. 15-24
    • Finzer, P.1    Aguilar-Lemarroy, A.2    Rösl, F.3
  • 75
    • 0036364468 scopus 로고    scopus 로고
    • Immune evasion in human papillomavirus-associated cervical cancer
    • Tindle RW. Immune evasion in human papillomavirus-associated cervical cancer. Nature Rev Cancer 2002;2:1-7.
    • (2002) Nature Rev Cancer , vol.2 , pp. 1-7
    • Tindle, R.W.1
  • 76
    • 0033740178 scopus 로고    scopus 로고
    • Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways
    • Goodwin EC, DiMaio D. Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways. Proc Natl Acad Sci USA 2000;97:12513-8.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12513-12518
    • Goodwin, E.C.1    DiMaio, D.2
  • 77
    • 0037229178 scopus 로고    scopus 로고
    • Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells
    • DeFilippis RA, Goodwin EC, Wu L, DiMaio D. Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells. J Virol 2003;77:1551-63.
    • (2003) J Virol , vol.77 , pp. 1551-1563
    • DeFilippis, R.A.1    Goodwin, E.C.2    Wu, L.3    DiMaio, D.4
  • 78
    • 0034331178 scopus 로고    scopus 로고
    • Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways
    • Wells SI, Francis DA, Karpova AY, Dowhanick JJ, Benson JD, Howley PM. Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways. EMBO J 2000; 19: 5762-71.
    • (2000) EMBO J , vol.19 , pp. 5762-5771
    • Wells, S.I.1    Francis, D.A.2    Karpova, A.Y.3    Dowhanick, J.J.4    Benson, J.D.5    Howley, P.M.6
  • 79
    • 0033932984 scopus 로고    scopus 로고
    • Clonality of precursors of cervical cancer and their genetical links to invasive cancer
    • Guo Z, Ponten F, Wilander E, Ponten J. Clonality of precursors of cervical cancer and their genetical links to invasive cancer. Mod Pathol 2000;13:606-13.
    • (2000) Mod Pathol , vol.13 , pp. 606-613
    • Guo, Z.1    Ponten, F.2    Wilander, E.3    Ponten, J.4
  • 80
    • 0038677462 scopus 로고    scopus 로고
    • A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques
    • Ziegert C, Wentzensen N, Vinokurova S, Kisseljov F, Einenkel J, Hoeckel M, von Knebel Doeberitz M. A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques. Oncogene 2003;22:3977-84.
    • (2003) Oncogene , vol.22 , pp. 3977-3984
    • Ziegert, C.1    Wentzensen, N.2    Vinokurova, S.3    Kisseljov, F.4    Einenkel, J.5    Hoeckel, M.6    Von Knebel Doeberitz, M.7
  • 81
    • 0028937867 scopus 로고
    • Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells
    • Jeon S, Allen-Hoffmann BL, Lambert PF. Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J Virol 1995;69:2989-97.
    • (1995) J Virol , vol.69 , pp. 2989-2997
    • Jeon, S.1    Allen-Hoffmann, B.L.2    Lambert, P.F.3
  • 83
    • 0039488192 scopus 로고
    • Introduction of human chromosome 11 via microcell transfer controls tumorigenic expression of HeLa cells
    • Saxon PJ, Srivatsan ES, Stanbridge EJ. Introduction of human chromosome 11 via microcell transfer controls tumorigenic expression of HeLa cells. EMBO J 1986;5:3461-6.
    • (1986) EMBO J , vol.5 , pp. 3461-3466
    • Saxon, P.J.1    Srivatsan, E.S.2    Stanbridge, E.J.3
  • 84
    • 0033514927 scopus 로고    scopus 로고
    • Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization
    • Bleuel K, Popp S, Fusenig NE, Stanbridge EJ, Boukamp P. Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization. Proc Natl Acad Sci USA 1999;96:2065-70.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2065-2070
    • Bleuel, K.1    Popp, S.2    Fusenig, N.E.3    Stanbridge, E.J.4    Boukamp, P.5
  • 89
    • 0030060945 scopus 로고    scopus 로고
    • FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: Direct evidence for the coincidence of viral integration sites and fragile sites
    • Wilke CM, Hall BK, Hoge A, Paradee W, Smith DI, Glover TW. FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites. Hum Mol Genet 1996;5:187-95.
    • (1996) Hum Mol Genet , vol.5 , pp. 187-195
    • Wilke, C.M.1    Hall, B.K.2    Hoge, A.3    Paradee, W.4    Smith, D.I.5    Glover, T.W.6
  • 91
    • 0035753424 scopus 로고    scopus 로고
    • FRA3B and other common fragile sites: The weakest link
    • Huebner K, Croce CM. FRA3B and other common fragile sites: the weakest link. Nature Cancer Rev 2001;1:214-21.
    • (2001) Nature Cancer Rev , vol.1 , pp. 214-221
    • Huebner, K.1    Croce, C.M.2
  • 93
    • 0036730664 scopus 로고    scopus 로고
    • The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo
    • Verschuren EW, Klefstrom J, Evan GI, Jones N. The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo. Cancer Cell 2002;2:229-41.
    • (2002) Cancer Cell , vol.2 , pp. 229-241
    • Verschuren, E.W.1    Klefstrom, J.2    Evan, G.I.3    Jones, N.4
  • 94
    • 0032478547 scopus 로고    scopus 로고
    • Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1
    • Jin DY, Spencer F, Jeang KT. Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 1998;93:81-91.
    • (1998) Cell , vol.93 , pp. 81-91
    • Jin, D.Y.1    Spencer, F.2    Jeang, K.T.3


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