-
1
-
-
33745700204
-
Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis
-
Halder, S. K., G. Anumanthan, R. Maddula, J. Mann, A. Chytil, A. L. Gonzalez, M. K. Washington, H. L. Moses, R. D. Beauchamp & P. K. Datta: Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis. Cancer Res, 66, 6156-66 (2006)
-
(2006)
Cancer Res
, vol.66
, pp. 6156-6166
-
-
Halder, S.K.1
Anumanthan, G.2
Maddula, R.3
Mann, J.4
Chytil, A.5
Gonzalez, A.L.6
Washington, M.K.7
Moses, H.L.8
Beauchamp, R.D.9
Datta, P.K.10
-
2
-
-
0033958515
-
Molecular cloning and characterization of human MAWD, a novel protein containing WD-40 repeats frequently overexpressed in breast cancer
-
Matsuda, S., R. Katsumata, T. Okuda, T. Yamamoto, K. Miyazaki, T. Senga, K. Machida, A. A. Thant, S. Nakatsugawa & M. Hamaguchi: Molecular cloning and characterization of human MAWD, a novel protein containing WD-40 repeats frequently overexpressed in breast cancer. Cancer Res, 60, 13-7 (2000) (Pubitemid 30058721)
-
(2000)
Cancer Research
, vol.60
, Issue.1
, pp. 13-17
-
-
Matsuda, S.1
Katsumata, R.2
Okuda, T.3
Yamamoto, T.4
Miyazaki, K.5
Senga, T.6
Machida, K.7
Thant, A.A.8
Nakatsugawa, S.9
Hamaguchi, M.10
-
3
-
-
45149131771
-
Conditional switches for extracellular matrix patterning in Drosophila melanogaster
-
Khokhar, A., N. Chen, J. P. Yuan, Y. Li, G. N. Landis, G. Beaulieu, H. Kaur & J. Tower: Conditional switches for extracellular matrix patterning in Drosophila melanogaster. Genetics, 178, 1283-93 (2008)
-
(2008)
Genetics
, vol.178
, pp. 1283-1293
-
-
Khokhar, A.1
Chen, N.2
Yuan, J.P.3
Li, Y.4
Landis, G.N.5
Beaulieu, G.6
Kaur, H.7
Tower, J.8
-
4
-
-
1442336006
-
Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis
-
DOI 10.1038/ng1306
-
Chen, W. V., J. Delrow, P. D. Corrin, J. P. Frazier & P. Soriano: Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis. Nat Genet, 36, 304-12 (2004) (Pubitemid 38282758)
-
(2004)
Nature Genetics
, vol.36
, Issue.3
, pp. 304-312
-
-
Chen, W.V.1
Delrow, J.2
Corrin, P.D.3
Frazier, J.P.4
Soriano, P.5
-
5
-
-
0035664074
-
WD-repeat proteins: Structure characteristics, biological function, and their involvement in human diseases
-
Li, D. & R. Roberts: WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases. Cell Mol Life Sci, 58, 2085-97 (2001) (Pubitemid 34016977)
-
(2001)
Cellular and Molecular Life Sciences
, vol.58
, Issue.14
, pp. 2085-2097
-
-
Li, D.1
Roberts, R.2
-
6
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
DOI 10.1038/nature02006
-
Derynck, R. & Y. E. Zhang: Smad-dependent and Smadindependent pathways in TGF-beta family signalling. Nature, 425, 577-84 (2003) (Pubitemid 37280136)
-
(2003)
Nature
, vol.425
, Issue.6958
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
7
-
-
0032430075
-
Signal transduction by transforming growth factor-β: A cooperative paradigm with extensive negative regulation
-
Engel, M. E., P. K. Datta & H. L. Moses: Signal transduction by transforming growth factor-beta: a cooperative paradigm with extensive negative regulation. J Cell Biochem Suppl, 30-31, 111-22 (1998) (Pubitemid 29028732)
-
(1998)
Journal of Cellular Biochemistry
, Issue.SUPPL. 30-31
, pp. 111-122
-
-
Engel, M.E.1
Datta, P.K.2
Moses, H.L.3
-
8
-
-
0031034589
-
Identification of Smad2, a human Mad-related protein in the transforming growth factor β signaling pathway
-
DOI 10.1074/jbc.272.5.2896
-
Nakao, A., E. Roijer, T. Imamura, S. Souchelnytskyi, G. Stenman, C. H. Heldin & P. ten Dijke: Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway. J Biol Chem, 272, 2896-900 (1997) (Pubitemid 27053339)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.5
, pp. 2896-2900
-
-
Nakao, A.1
Roijer, E.2
Imamura, T.3
Souchelnytskyi, S.4
Stenman, G.5
Heldin, C.-H.6
Dijke, P.T.7
-
9
-
-
0029834067
-
Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways
-
DOI 10.1038/383832a0
-
Lagna, G., A. Hata, A. Hemmati-Brivanlou & J. Massague: Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature, 383, 832-6 (1996) (Pubitemid 26372668)
-
(1996)
Nature
, vol.383
, Issue.6603
, pp. 832-836
-
-
Lagna, G.1
Hata, A.2
Hemmati-Brivanlou, A.3
Massague, J.4
-
10
-
-
0029786212
-
Receptor-associated Mad homologues synergize as effectors of the TGF-β response
-
DOI 10.1038/383168a0
-
Zhang, Y., X. Feng, R. We & R. Derynck: Receptorassociated Mad homologues synergize as effectors of the TGF-beta response. Nature, 383, 168-72 (1996) (Pubitemid 26303979)
-
(1996)
Nature
, vol.383
, Issue.6596
, pp. 168-172
-
-
Zhang, Y.1
Feng, X.-H.2
Wu, R.-Y.3
Derynck, R.4
-
12
-
-
0034695483
-
Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor β-related signaling
-
DOI 10.1074/jbc.275.3.2063
-
Sirard, C., S. Kim, C. Mirtsos, P. Tadich, P. A. Hoodless, A. Itie, R. Maxson, J. L. Wrana & T. W. Mak: Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor betarelated signaling. J Biol Chem, 275, 2063-70 (2000) (Pubitemid 30060834)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.3
, pp. 2063-2070
-
-
Sirard, C.1
Sammy, K.2
Mirtsos, C.3
Tadich, P.4
Hoodless, P.A.5
Itie, A.6
Maxson, R.7
Wrana, J.L.8
Mak, T.W.9
-
13
-
-
0037155854
-
Transforming growth factor β1 induces proliferation in colon carcinoma cells by ras-dependent, smad-independent down-regulation of p21cip1
-
DOI 10.1074/jbc.M107646200
-
Yan, Z., G. Y. Kim, X. Deng & E. Friedman: Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1. J Biol Chem, 277, 9870-9 (2002) (Pubitemid 34968092)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.12
, pp. 9870-9879
-
-
Yan, Z.1
Kim, G.-Y.2
Deng, X.3
Friedman, E.4
-
14
-
-
6944248910
-
Activation of the Erk pathway is required for TGF-β1-induced EMT in vitro
-
DOI 10.1593/neo.04241
-
Xie, L., B. K. Law, A. M. Chytil, K. A. Brown, M. E. Aakre & H. L. Moses: Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia, 6, 603-10 (2004) (Pubitemid 39411098)
-
(2004)
Neoplasia
, vol.6
, Issue.5
, pp. 603-610
-
-
Xie, L.1
Law, B.K.2
Chytil, A.M.3
Brown, K.A.4
Aakre, M.E.5
Moses, H.L.6
-
15
-
-
33646862859
-
TGFβ-mediated RhoA expression is necessary for epithelial- mesenchymal transition in the embryonic chick heart
-
DOI 10.1002/dvdy.20771
-
Tavares, A. L., M. E. Mercado-Pimentel, R. B. Runyan & G. T. Kitten: TGF beta-mediated RhoA expression is necessary for epithelial-mesenchymal transition in the embryonic chick heart. Dev Dyn, 235, 1589-98 (2006) (Pubitemid 43787961)
-
(2006)
Developmental Dynamics
, vol.235
, Issue.6
, pp. 1589-1598
-
-
Tavares, A.L.P.1
Mercado-Pimentel, M.E.2
Runyan, R.B.3
Kitten, G.T.4
-
16
-
-
33748697413
-
Transforming growth factor-β1 regulates macrophage migration via RhoA
-
DOI 10.1182/blood-2005-10-009191
-
Kim, J. S., J. G. Kim, M. Y. Moon, C. Y. Jeon, H. Y. Won, H. J. Kim, Y. J. Jeon, J. Y. Seo, J. I. Kim, J. Kim, J. Y. Lee, P. H. Kim & J. B. Park: Transforming growth factor-beta1 regulates macrophage migration via RhoA. Blood, 108, 1821-9 (2006) (Pubitemid 44394988)
-
(2006)
Blood
, vol.108
, Issue.6
, pp. 1821-1829
-
-
Kim, J.-S.1
Kim, J.-G.2
Moon, M.-Y.3
Jeon, C.-Y.4
Won, H.-Y.5
Kim, H.-J.6
Jeon, Y.-J.7
Seo, J.-Y.8
Kim, J.-I.9
Kim, J.10
Lee, J.-Y.11
Kim, P.-H.12
Park, J.-B.13
-
17
-
-
51349164414
-
Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
-
Wang, S. E., B. Xiang, M. Guix, M. G. Olivares, J. Parker, C. H. Chung, A. Pandiella & C. L. Arteaga: Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab. Mol Cell Biol, 28, 5605-20 (2008)
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5605-5620
-
-
Wang, S.E.1
Xiang, B.2
Guix, M.3
Olivares, M.G.4
Parker, J.5
Chung, C.H.6
Pandiella, A.7
Arteaga, C.L.8
-
18
-
-
49949114895
-
Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo
-
Kattla, J. J., R. M. Carew, M. Heljic, C. Godson & D. P. Brazil: Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo. Am J Physiol Renal Physiol, 295, F215-25 (2008)
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Kattla, J.J.1
Carew, R.M.2
Heljic, M.3
Godson, C.4
Brazil, D.P.5
-
19
-
-
39749170615
-
TGF-beta1 increases motility and alphavbeta3 integrin up-regulation via PI3K, Akt and NF-kappaB-dependent pathway in human chondrosarcoma cells
-
Yeh, Y. Y., C. C. Chiao, W. Y. Kuo, Y. C. Hsiao, Y. J. Chen, Y. Y. Wei, T. H. Lai, Y. C. Fong & C. H. Tang: TGF-beta1 increases motility and alphavbeta3 integrin up-regulation via PI3K, Akt and NF-kappaB-dependent pathway in human chondrosarcoma cells. Biochem Pharmacol, 75, 1292-301 (2008)
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1292-1301
-
-
Yeh, Y.Y.1
Chiao, C.C.2
Kuo, W.Y.3
Hsiao, Y.C.4
Chen, Y.J.5
Wei, Y.Y.6
Lai, T.H.7
Fong, Y.C.8
Tang, C.H.9
-
20
-
-
1842421169
-
Requirement of TGF-β Receptor-Dependent Activation of c-Jun N-Terminal Kinases (JNKs)/Stress-Activated Protein Kinases (Sapks) for TGF-β Up-Regulation of the Urokinase-Type Plasminogen Activator Receptor
-
DOI 10.1002/jcp.10469
-
Yue, J., B. Sun, G. Liu & K. M. Mulder: Requirement of TGF-beta receptor-dependent activation of c-Jun Nterminal kinases (JNKs)/stress-activated protein kinases (Sapks) for TGF-beta up-regulation of the urokinase-type plasminogen activator receptor. J Cell Physiol, 199, 284-92 (2004) (Pubitemid 38436755)
-
(2004)
Journal of Cellular Physiology
, vol.199
, Issue.2
, pp. 284-292
-
-
Yue, J.1
Sun, B.2
Liu, G.3
Mulder, K.M.4
-
21
-
-
4644284605
-
A critical role of tropomyosins in TGF-β regulation of the actin cytoskeleton and cell motility in epithelial cells
-
DOI 10.1091/mbc.E04-04-0353
-
Bakin, A. V., A. Safina, C. Rinehart, C. Daroqui, H. Darbary & D. M. Helfman: A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells. Mol Biol Cell, 15, 4682-94 (2004) (Pubitemid 39299114)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.10
, pp. 4682-4694
-
-
Bakin, A.V.1
Safina, A.2
Rinehart, C.3
Daroqui, C.4
Darbary, H.5
Helfman, D.M.6
-
22
-
-
51049090175
-
Transforming growth factor-beta (TGF-beta) and TGF-beta-associated kinase 1 are required for R-Rasmediated transformation of mammary epithelial cells
-
Erdogan, M., A. Pozzi, N. Bhowmick, H. L. Moses & R. Zent: Transforming growth factor-beta (TGF-beta) and TGF-beta-associated kinase 1 are required for R-Rasmediated transformation of mammary epithelial cells. Cancer Res, 68, 6224-31 (2008)
-
(2008)
Cancer Res
, vol.68
, pp. 6224-6231
-
-
Erdogan, M.1
Pozzi, A.2
Bhowmick, N.3
Moses, H.L.4
Zent, R.5
-
23
-
-
60549095395
-
TGF-beta-mediated activation of RhoA signalling is required for efficient (V12)HaRas and (V600E)BRAF transformation
-
Fleming, Y. M., G. J. Ferguson, L. C. Spender, J. Larsson, S. Karlsson, B. W. Ozanne, R. Grosse & G. J. Inman: TGF-beta-mediated activation of RhoA signalling is required for efficient (V12)HaRas and (V600E)BRAF transformation. Oncogene, 28, 983-93 (2009)
-
(2009)
Oncogene
, vol.28
, pp. 983-993
-
-
Fleming, Y.M.1
Ferguson, G.J.2
Spender, L.C.3
Larsson, J.4
Karlsson, S.5
Ozanne, B.W.6
Grosse, R.7
Inman, G.J.8
-
24
-
-
3543112696
-
Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor β
-
Du, J., B. Jiang, R. J. Coffey & J. Barnard: Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta. Mol Cancer Res, 2, 233-41 (2004) (Pubitemid 39031084)
-
(2004)
Molecular Cancer Research
, vol.2
, Issue.4
, pp. 233-241
-
-
Du, J.1
Jiang, B.2
Coffey, R.J.3
Barnard, J.4
-
25
-
-
72049091524
-
Targeting the transforming growth factor-beta signaling pathway in human cancer
-
Nagaraj, N. S. & P. K. Datta: Targeting the transforming growth factor-beta signaling pathway in human cancer. Expert Opin Investig Drugs, 19, 77-91 (2010)
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 77-91
-
-
Nagaraj, N.S.1
Datta, P.K.2
-
26
-
-
0030611757
-
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
-
DOI 10.1038/39369
-
Nakao, A., M. Afrakhte, A. Moren, T. Nakayama, J. L. Christian, R. Heuchel, S. Itoh, M. Kawabata, N. E. Heldin, C. H. Heldin & P. ten Dijke: Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. Nature, 389, 631-5 (1997) (Pubitemid 27446184)
-
(1997)
Nature
, vol.389
, Issue.6651
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchef, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.-E.9
Heldin, C.-H.10
Ten Dijke, P.11
-
27
-
-
0030765945
-
Smad6 inhibits signalling by the TGF-β superfamily
-
DOI 10.1038/39355
-
Imamura, T., M. Takase, A. Nishihara, E. Oeda, J. Hanai, M. Kawabata & K. Miyazono: Smad6 inhibits signalling by the TGF-beta superfamily. Nature, 389, 622-6 (1997) (Pubitemid 27446182)
-
(1997)
Nature
, vol.389
, Issue.6651
, pp. 622-626
-
-
Imamura, T.1
Takase, M.2
Nishihara, A.3
Oeda, E.4
Hanai, J.-I.5
Kawabata, M.6
Miyazono, K.7
-
28
-
-
0032553555
-
The type II transforming growth factor (TGF)-β receptor-interacting protein TRIP-1 acts as a modulator of the TGF-β response
-
DOI 10.1074/jbc.273.47.31455
-
Choy, L. & R. Derynck: The type II transforming growth factor (TGF)-beta receptor-interacting protein TRIP-1 acts as a modulator of the TGF-beta response. J Biol Chem, 273, 31455-62 (1998) (Pubitemid 28533166)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.47
, pp. 31455-31462
-
-
Choy, L.1
Derynck, R.2
-
29
-
-
0029157432
-
A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor
-
Chen, R. H., P. J. Miettinen, E. M. Maruoka, L. Choy & R. Derynck: A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor. Nature, 377, 548-52 (1995)
-
(1995)
Nature
, vol.377
, pp. 548-552
-
-
Chen, R.H.1
Miettinen, P.J.2
Maruoka, E.M.3
Choy, L.4
Derynck, R.5
-
30
-
-
0033996038
-
STRAP and Smad7 synergize in the inhibition of transforming growth factor β signaling
-
DOI 10.1128/MCB.20.9.3157-3167.2000
-
Datta, P. K. & H. L. Moses: STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling. Mol Cell Biol, 20, 3157-67 (2000) (Pubitemid 30215028)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.9
, pp. 3157-3167
-
-
Datta, P.K.1
Moses, H.L.2
-
31
-
-
19544368435
-
Smad7 induces tumorigenicity by blocking TGF-β-induced growth inhibition and apoptosis
-
DOI 10.1016/j.yexcr.2005.03.009, PII S0014482705001151
-
Halder, S. K., R. D. Beauchamp & P. K. Datta: Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis. Exp Cell Res, 307, 231-46 (2005) (Pubitemid 40732749)
-
(2005)
Experimental Cell Research
, vol.307
, Issue.1
, pp. 231-246
-
-
Halder, S.K.1
Beauchamp, R.D.2
Datta, P.K.3
-
32
-
-
67649604297
-
Down-regulation of 3-phosphoinositide-dependent protein kinase-1 levels inhibits migration and experimental metastasis of human breast cancer cells
-
Liu, Y., J. Wang, M. Wu, W. Wan, R. Sun, D. Yang, X. Sun, D. Ma, G. Ying & N. Zhang: Down-regulation of 3-phosphoinositide-dependent protein kinase-1 levels inhibits migration and experimental metastasis of human breast cancer cells. Mol Cancer Res, 7, 944-54 (2009)
-
(2009)
Mol Cancer Res
, vol.7
, pp. 944-954
-
-
Liu, Y.1
Wang, J.2
Wu, M.3
Wan, W.4
Sun, R.5
Yang, D.6
Sun, X.7
Ma, D.8
Ying, G.9
Zhang, N.10
-
33
-
-
58249092754
-
New anti-cancer role for PDK1 inhibitors: Preventing resistance to tamoxifen
-
Peifer, C. & D. R. Alessi: New anti-cancer role for PDK1 inhibitors: preventing resistance to tamoxifen. Biochem J, 417, e5-7 (2009)
-
(2009)
Biochem J
, vol.417
-
-
Peifer, C.1
Alessi, D.R.2
-
34
-
-
69949121663
-
Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells
-
Westmoreland, J. J., Q. Wang, M. Bouzaffour, S. J. Baker & B. Sosa-Pineda: Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells. Dev Biol, 334, 285-98 (2009)
-
(2009)
Dev Biol
, vol.334
, pp. 285-298
-
-
Westmoreland, J.J.1
Wang, Q.2
Bouzaffour, M.3
Baker, S.J.4
Sosa-Pineda, B.5
-
35
-
-
53149140694
-
Potential inhibition of PDK1/Akt signaling by phenothiazines suppresses cancer cell proliferation and survival
-
Choi, J. H., Y. R. Yang, S. K. Lee, S. H. Kim, Y. H. Kim, J. Y. Cha, S. W. Oh, J. R. Ha, S. H. Ryu & P. G. Suh: Potential inhibition of PDK1/Akt signaling by phenothiazines suppresses cancer cell proliferation and survival. Ann N Y Acad Sci, 1138, 393-403 (2008)
-
(2008)
Ann N y Acad Sci
, vol.1138
, pp. 393-403
-
-
Choi, J.H.1
Yang, Y.R.2
Lee, S.K.3
Kim, S.H.4
Kim, Y.H.5
Cha, J.Y.6
Oh, S.W.7
Ha, J.R.8
Ryu, S.H.9
Suh, P.G.10
-
36
-
-
27144480288
-
+/- mice
-
DOI 10.1016/j.cub.2005.08.066, PII S0960982205010389
-
Bayascas, J. R., N. R. Leslie, R. Parsons, S. Fleming & D. R. Alessi: Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN (+/-) mice. Curr Biol, 15, 1839-46 (2005) (Pubitemid 41501519)
-
(2005)
Current Biology
, vol.15
, Issue.20
, pp. 1839-1846
-
-
Bayascas, J.R.1
Leslie, N.R.2
Parsons, R.3
Fleming, S.4
Alessi, D.R.5
-
37
-
-
51849098272
-
Drug discovery approaches targeting the PI3K/Akt pathway in cancer
-
Garcia-Echeverria, C. & W. R. Sellers: Drug discovery approaches targeting the PI3K/Akt pathway in cancer. Oncogene, 27, 5511-26 (2008)
-
(2008)
Oncogene
, vol.27
, pp. 5511-5526
-
-
Garcia-Echeverria, C.1
Sellers, W.R.2
-
38
-
-
19944433628
-
Identification and characterization of pleckstrin-homology-domain- dependent and isoenzyme-specific Akt inhibitors
-
DOI 10.1042/BJ20041140
-
Barnett, S. F., D. Defeo-Jones, S. Fu, P. J. Hancock, K. M. Haskell, R. E. Jones, J. A. Kahana, A. M. Kral, K. Leander, L. L. Lee, J. Malinowski, E. M. McAvoy, D. D. Nahas, R. G. Robinson & H. E. Huber: Identification and characterization of pleckstrin-homology-domaindependent and isoenzyme-specific Akt inhibitors. Biochem J, 385, 399-408 (2005) (Pubitemid 40165072)
-
(2005)
Biochemical Journal
, vol.385
, Issue.2
, pp. 399-408
-
-
Barnett, S.F.1
Defeo-Jones, D.2
Fu, S.3
Hancock, P.J.4
Haskell, K.M.5
Jones, R.E.6
Kahana, J.A.7
Kral, A.M.8
Leander, K.9
Lee, L.L.10
Malinowski, J.11
McAvoy, E.M.12
Nahas, D.D.13
Robinson, R.G.14
Huber, H.E.15
-
39
-
-
30044434463
-
Regulation of transforming growth factor-β signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein
-
DOI 10.1074/jbc.M507539200
-
Seong, H. A., H. Jung, H. S. Choi, K. T. Kim & H. Ha: Regulation of transforming growth factor-beta signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein. J Biol Chem, 280, 42897-908 (2005) (Pubitemid 43049252)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.52
, pp. 42897-42908
-
-
Seong, H.-A.1
Jung, H.2
Choi, H.-S.3
Kim, K.-T.4
Ha, H.5
-
40
-
-
34249737498
-
3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-β-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins
-
DOI 10.1074/jbc.M609279200
-
Seong, H. A., H. Jung, K. T. Kim & H. Ha: 3-Phosphoinositide- dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins. J Biol Chem, 282, 12272-89 (2007) (Pubitemid 47100723)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 12272-12289
-
-
Seong, H.-A.1
Jung, H.2
Kim, K.-T.3
Ha, H.4
-
41
-
-
0024965767
-
Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development
-
Rosengard, A. M., H. C. Krutzsch, A. Shearn, J. R. Biggs, E. Barker, I. M. Margulies, C. R. King, L. A. Liotta & P. S. Steeg: Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development. Nature, 342, 177-80 (1989)
-
(1989)
Nature
, vol.342
, pp. 177-180
-
-
Rosengard, A.M.1
Krutzsch, H.C.2
Shearn, A.3
Biggs, J.R.4
Barker, E.5
Margulies, I.M.6
King, C.R.7
Liotta, L.A.8
Steeg, P.S.9
-
42
-
-
0025753514
-
Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells
-
Leone, A., U. Flatow, C. R. King, M. A. Sandeen, I. M. Margulies, L. A. Liotta & P. S. Steeg: Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell, 65, 25-35 (1991) (Pubitemid 121001210)
-
(1991)
Cell
, vol.65
, Issue.1
, pp. 25-35
-
-
Leone, A.1
Flatow, U.2
Richter King, C.3
Sandeen, M.A.4
Margulies, I.M.K.5
Liotta, L.A.6
Steeg, P.S.7
-
43
-
-
0026428162
-
Expression of the antimetastatic gene nm23 in human breast cancer: An association with good prognosis
-
Hennessy, C., J. A. Henry, F. E. May, B. R. Westley, B. Angus & T. W. Lennard: Expression of the antimetastatic gene nm23 in human breast cancer: an association with good prognosis. J Natl Cancer Inst, 83, 281-5 (1991)
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 281-285
-
-
Hennessy, C.1
Henry, J.A.2
May, F.E.3
Westley, B.R.4
Angus, B.5
Lennard, T.W.6
-
44
-
-
0035009693
-
Interplay between the antimetastatic nm23 and the retinoblastoma-related Rb2/p130 genes in promoting neuronal differentiation of PC12 cells
-
DOI 10.1038/sj.cdd.4400842
-
Lombardi, D., E. Palescandolo, A. Giordano & M. G. Paggi: Interplay between the antimetastatic nm23 and the retinoblastoma-related Rb2/p130 genes in promoting neuronal differentiation of PC12 cells. Cell Death Differ, 8, 470-6 (2001) (Pubitemid 32492767)
-
(2001)
Cell Death and Differentiation
, vol.8
, Issue.5
, pp. 470-476
-
-
Lombardi, D.1
Palescandolo, E.2
Giordano, A.3
Paggi, M.G.4
-
45
-
-
77958596320
-
Effects of tumor metastasis suppressor gene nm23-H1 on invasion and proliferation of cervical cancer cell lines
-
Yang, Y., S. Lu, M. F. Li & Z. H. Wang: (Effects of tumor metastasis suppressor gene nm23-H1 on invasion and proliferation of cervical cancer cell lines.). Ai Zheng, 28, 702-7 (2009)
-
(2009)
Ai Zheng
, vol.28
, pp. 702-707
-
-
Yang, Y.1
Lu, S.2
Li, M.F.3
Wang, Z.H.4
-
46
-
-
0027304816
-
Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: Effects on tumor metastatic potential, colonization and enzymatic activity
-
Leone, A., U. Flatow, K. VanHoutte & P. S. Steeg: Transfection of human nm23-H1 into the human MDAMB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity. Oncogene, 8, 2325-33 (1993) (Pubitemid 23252360)
-
(1993)
Oncogene
, vol.8
, Issue.9
, pp. 2325-2333
-
-
Leone, A.1
Flatow, U.2
VanHoutte, K.3
Steeg, P.S.4
-
47
-
-
0028129166
-
The role of nm23 in transforming growth factor β1-mediated adherence and growth arrest
-
Hsu, S., F. Huang, L. Wang, S. Banerjee, S. Winawer & E. Friedman: The role of nm23 in transforming growth factor beta 1-mediated adherence and growth arrest. Cell Growth Differ, 5, 909-17 (1994) (Pubitemid 24275105)
-
(1994)
Cell Growth and Differentiation
, vol.5
, Issue.9
, pp. 909-917
-
-
Hsu, S.1
Huang, F.2
Wang, L.3
Banerjee, S.4
Winawer, S.5
Friedman, E.6
-
48
-
-
34249674439
-
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-β (TGF-β) receptor-interacting protein, and negatively regulates TGF-β signaling
-
DOI 10.1074/jbc.M609832200
-
Seong, H. A., H. Jung & H. Ha: NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factorbeta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling. J Biol Chem, 282, 12075-96 (2007) (Pubitemid 47100716)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 12075-12096
-
-
Seong, H.-A.1
Jung, H.2
Ha, H.3
-
49
-
-
36849054976
-
NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function
-
DOI 10.1074/jbc.M705181200
-
Jung, H., H. A. Seong & H. Ha: NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function. J Biol Chem, 282, 35293-307 (2007) (Pubitemid 350232484)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.48
, pp. 35293-35307
-
-
Jung, H.1
Seong, H.-A.2
Ha, H.3
-
50
-
-
0038274163
-
Links between tumor suppressors: p53 is required for TGF-β gene responses by cooperating with Smads
-
DOI 10.1016/S0092-8674(03)00308-8
-
Cordenonsi, M., S. Dupont, S. Maretto, A. Insinga, C. Imbriano & S. Piccolo: Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. Cell, 113, 301-14 (2003) (Pubitemid 36556113)
-
(2003)
Cell
, vol.113
, Issue.3
, pp. 301-314
-
-
Cordenonsi, M.1
Dupont, S.2
Maretto, S.3
Insinga, A.4
Imbriano, C.5
Piccolo, S.6
-
51
-
-
28044468016
-
EWS-ETS oncoproteins: The linchpins of Ewing tumors
-
DOI 10.1016/j.gene.2005.08.007, PII S0378111905005056
-
Janknecht, R.: EWS-ETS oncoproteins: the linchpins of Ewing tumors. Gene, 363, 1-14 (2005) (Pubitemid 41691887)
-
(2005)
Gene
, vol.363
, Issue.1-2
, pp. 1-14
-
-
Janknecht, R.1
-
52
-
-
34248203558
-
Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development
-
DOI 10.1172/JCI31222
-
Li, H., W. Watford, C. Li, A. Parmelee, M. A. Bryant, C. Deng, J. O'Shea & S. B. Lee: Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development. J Clin Invest, 117, 1314-23 (2007) (Pubitemid 46718419)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.5
, pp. 1314-1323
-
-
Li, H.1
Watford, W.2
Li, C.3
Parmelee, A.4
Bryant, M.A.5
Deng, C.6
O'Shea, J.7
Sean, B.L.8
-
53
-
-
0027230568
-
Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation
-
May, W. A., M. L. Gishizky, S. L. Lessnick, L. B. Lunsford, B. C. Lewis, O. Delattre, J. Zucman, G. Thomas & C. T. Denny: Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proc Natl Acad Sci U S A, 90, 5752-6 (1993) (Pubitemid 23176240)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.12
, pp. 5752-5756
-
-
May, W.A.1
Gishizky, M.L.2
Lessnick, S.L.3
Lunsford, L.B.4
Lewis, B.C.5
Delattre, O.6
Zucman, J.7
Thomas, G.8
Denny, C.T.9
-
54
-
-
0027362619
-
The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI- 1
-
May, W. A., S. L. Lessnick, B. S. Braun, M. Klemsz, B. C. Lewis, L. B. Lunsford, R. Hromas & C. T. Denny: The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Mol Cell Biol, 13, 7393-8 (1993) (Pubitemid 23354263)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.12
, pp. 7393-7398
-
-
May, W.A.1
Lessnick, S.L.2
Braun, B.S.3
Klemsz, M.4
Lewis, B.C.5
Lunsford, L.B.6
Hromas, R.7
Denny, C.T.8
-
55
-
-
0027136095
-
EWS/Fli-1 chimeric protein is a transcriptional activator
-
Ohno, T., V. N. Rao & E. S. Reddy: EWS/Fli-1 chimeric protein is a transcriptional activator. Cancer Res, 53, 5859-63 (1993) (Pubitemid 24006149)
-
(1993)
Cancer Research
, vol.53
, Issue.24
, pp. 5859-5863
-
-
Ohno, T.1
Rao, V.N.2
Reddy, E.S.P.3
-
56
-
-
0032848660
-
Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLI1 oncoprotein
-
DOI 10.1038/13854
-
Hahm, K. B., K. Cho, C. Lee, Y. H. Im, J. Chang, S. G. Choi, P. H. Sorensen, C. J. Thiele & S. J. Kim: Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein. Nat Genet, 23, 222-7 (1999) (Pubitemid 29455398)
-
(1999)
Nature Genetics
, vol.23
, Issue.2
, pp. 222-227
-
-
Hahm, K.-B.1
Cho, K.2
Lee, C.3
Im, Y.-H.4
Chang, J.5
Choi, S.-G.6
Sorensen, P.H.B.7
Thiele, C.J.8
Kim, S.-J.9
-
57
-
-
0038662666
-
Cooperative interaction of EWS with CREB-binding protein selectively activates hepatocyte nuclear factor 4-mediated transcription
-
DOI 10.1074/jbc.M210234200
-
Araya, N., K. Hirota, Y. Shimamoto, M. Miyagishi, E. Yoshida, J. Ishida, S. Kaneko, M. Kaneko, T. Nakajima & A. Fukamizu: Cooperative interaction of EWS with CREBbinding protein selectively activates hepatocyte nuclear factor 4-mediated transcription. J Biol Chem, 278, 5427-32 (2003) (Pubitemid 36801059)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.7
, pp. 5427-5432
-
-
Araya, N.1
Hirota, K.2
Shimamoto, Y.3
Miyagishi, M.4
Yoshida, E.5
Ishida, J.6
Kaneko, S.7
Kaneko, M.8
Nakajima, T.9
Fukamizu, A.10
-
58
-
-
17044370533
-
EWS-FLI1 target genes recovered from Ewing's sarcoma chromatin
-
DOI 10.1038/sj.onc.1208455
-
Siligan, C., J. Ban, R. Bachmaier, L. Spahn, M. Kreppel, K. L. Schaefer, C. Poremba, D. N. Aryee & H. Kovar: EWSFLI1 target genes recovered from Ewing's sarcoma chromatin. Oncogene, 24, 2512-24 (2005) (Pubitemid 40593042)
-
(2005)
Oncogene
, vol.24
, Issue.15
, pp. 2512-2524
-
-
Siligan, C.1
Ban, J.2
Bachmaier, R.3
Spahn, L.4
Kreppel, M.5
Schaefer, K.-L.6
Poremba, C.7
Aryee, D.N.T.8
Kovar, H.9
-
59
-
-
33845333409
-
Oncogenic serine-threonine kinase receptor-associated protein modulates the function of ewing sarcoma protein through a novel mechanism
-
DOI 10.1158/0008-5472.CAN-06-1599
-
Anumanthan, G., S. K. Halder, D. B. Friedman & P. K. Datta: Oncogenic serine-threonine kinase receptor-associated protein modulates the function of Ewing sarcoma protein through a novel mechanism. Cancer Res, 66, 10824-32 (2006) (Pubitemid 44876978)
-
(2006)
Cancer Research
, vol.66
, Issue.22
, pp. 10824-10832
-
-
Anumanthan, G.1
Halder, S.K.2
Friedman, D.B.3
Datta, P.K.4
-
60
-
-
0032559647
-
Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells
-
DOI 10.1083/jcb.140.4.935
-
Spath, G. F. & M. C. Weiss: Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells. J Cell Biol, 140, 935-46 (1998) (Pubitemid 28141230)
-
(1998)
Journal of Cell Biology
, vol.140
, Issue.4
, pp. 935-946
-
-
Spath, G.F.1
Weiss, M.C.2
-
61
-
-
27144512719
-
HNF4α reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma
-
DOI 10.1038/sj.onc.1208794, PII 1208794
-
Lucas, B., K. Grigo, S. Erdmann, J. Lausen, L. Klein-Hitpass & G. U. Ryffel: HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma. Oncogene, 24, 6418-31 (2005) (Pubitemid 41486475)
-
(2005)
Oncogene
, vol.24
, Issue.42
, pp. 6418-6431
-
-
Lucas, B.1
Grigo, K.2
Erdmann, S.3
Lausen, J.4
Klein-Hitpass, L.5
Ryffel, G.U.6
-
62
-
-
67449116604
-
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells
-
Meurette, O., S. Stylianou, R. Rock, G. M. Collu, A. P. Gilmore & K. Brennan: Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells. Cancer Res, 69, 5015-22 (2009)
-
(2009)
Cancer Res
, vol.69
, pp. 5015-5022
-
-
Meurette, O.1
Stylianou, S.2
Rock, R.3
Collu, G.M.4
Gilmore, A.P.5
Brennan, K.6
-
63
-
-
66649136112
-
Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells
-
Kuo, C. T., B. C. Chen, C. C. Yu, C. M. Weng, M. J. Hsu, C. C. Chen, M. C. Chen, C. M. Teng, S. L. Pan, M. Y. Bien, C. H. Shih & C. H. Lin: Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells. J Biomed Sci, 16, 43 (2009)
-
(2009)
J Biomed Sci
, vol.16
, pp. 43
-
-
Kuo, C.T.1
Chen, B.C.2
Yu, C.C.3
Weng, C.M.4
Hsu, M.J.5
Chen, C.C.6
Chen, M.C.7
Teng, C.M.8
Pan, S.L.9
Bien, M.Y.10
Shih, C.H.11
Lin, C.H.12
-
64
-
-
79959623312
-
Serinethreonine kinase receptor-associated protein (STRAP) inhibits apoptosis signal-regulating kinase 1 function through direct interaction
-
Jung, H., H. A. Seong, R. Manoharan & H. Ha: Serinethreonine kinase receptor-associated protein (STRAP) inhibits apoptosis signal-regulating kinase 1 function through direct interaction. J Biol Chem (2009)
-
(2009)
J Biol Chem
-
-
Jung, H.1
Seong, H.A.2
Manoharan, R.3
Ha, H.4
-
65
-
-
65449146296
-
ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis
-
Iriyama, T., K. Takeda, H. Nakamura, Y. Morimoto, T. Kuroiwa, J. Mizukami, T. Umeda, T. Noguchi, I. Naguro, H. Nishitoh, K. Saegusa, K. Tobiume, T. Homma, Y. Shimada, H. Tsuda, S. Aiko, I. Imoto, J. Inazawa, K. Chida, Y. Kamei, S. Kozuma, Y. Taketani, A. Matsuzawa & H. Ichijo: ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis. Embo J, 28, 843-53 (2009)
-
(2009)
Embo J
, vol.28
, pp. 843-853
-
-
Iriyama, T.1
Takeda, K.2
Nakamura, H.3
Morimoto, Y.4
Kuroiwa, T.5
Mizukami, J.6
Umeda, T.7
Noguchi, T.8
Naguro, I.9
Nishitoh, H.10
Saegusa, K.11
Tobiume, K.12
Homma, T.13
Shimada, Y.14
Tsuda, H.15
Aiko, S.16
Imoto, I.17
Inazawa, J.18
Chida, K.19
Kamei, Y.20
Kozuma, S.21
Taketani, Y.22
Matsuzawa, A.23
Ichijo, H.24
more..
-
66
-
-
70349998146
-
Serine threonine receptor-associated protein (STRAP) plays a role in the maintenance of mesenchymal morphology
-
Kashikar, N. D., J. Reiner, A. Datta & P. K. Datta: Serine threonine receptor-associated protein (STRAP) plays a role in the maintenance of mesenchymal morphology. Cell Signal, 22, 138-49 (2009)
-
(2009)
Cell Signal
, vol.22
, pp. 138-149
-
-
Kashikar, N.D.1
Reiner, J.2
Datta, A.3
Datta, P.K.4
-
67
-
-
0033557935
-
Unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA
-
Hunt, S. L., J. J. Hsuan, N. Totty & R. J. Jackson: unr, a cellular cytoplasmic RNA-binding protein with five coldshock domains, is required for internal initiation of translation of human rhinovirus RNA. Genes Dev, 13, 437-48 (1999) (Pubitemid 29108759)
-
(1999)
Genes and Development
, vol.13
, Issue.4
, pp. 437-448
-
-
Hunt, S.L.1
Hsuan, J.J.2
Totty, N.3
Jackson, R.J.4
-
68
-
-
0345549480
-
Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo
-
DOI 10.1038/sj.onc.1206645
-
Evans, J. R., S. A. Mitchell, K. A. Spriggs, J. Ostrowski, K. Bomsztyk, D. Ostarek & A. E. Willis: Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo. Oncogene, 22, 8012-20 (2003) (Pubitemid 37175865)
-
(2003)
Oncogene
, vol.22
, Issue.39
, pp. 8012-8020
-
-
Evans, J.R.1
Mitchell, S.A.2
Spriggs, K.A.3
Ostrowski, J.4
Bomsztyk, K.5
Ostarek, D.6
Willis, A.E.7
-
69
-
-
17644393497
-
Unrip is a component of SMN complexes active in snRNP assembly
-
DOI 10.1016/j.febslet.2005.03.034
-
Carissimi, C., J. Baccon, M. Straccia, P. Chiarella, A. Maiolica, A. Sawyer, J. Rappsilber & L. Pellizzoni: Unrip is a component of SMN complexes active in snRNP assembly. FEBS Lett, 579, 2348-54 (2005) (Pubitemid 40569503)
-
(2005)
FEBS Letters
, vol.579
, Issue.11
, pp. 2348-2354
-
-
Carissimi, C.1
Baccon, J.2
Straccia, M.3
Chiarella, P.4
Maiolica, A.5
Sawyer, A.6
Rappsilber, J.7
Pellizzoni, L.8
-
70
-
-
27544502473
-
Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization
-
DOI 10.1093/hmg/ddi343
-
Grimmler, M., S. Otter, C. Peter, F. Muller, A. Chari & U. Fischer: Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization. Hum Mol Genet, 14, 3099-111 (2005) (Pubitemid 41535474)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.20
, pp. 3099-3111
-
-
Grimmler, M.1
Otter, S.2
Peter, C.3
Muller, F.4
Chari, A.5
Fischer, U.6
-
71
-
-
27144482996
-
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress
-
DOI 10.1016/j.bbrc.2005.09.191, PII S0006291X05022254
-
Guo, D., J. Han, B. L. Adam, N. H. Colburn, M. H. Wang, Z. Dong, D. L. Eizirik, J. X. She & C. Y. Wang: Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. Biochem Biophys Res Commun, 337, 1308-18 (2005) (Pubitemid 41505265)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.337
, Issue.4
, pp. 1308-1318
-
-
Guo, D.1
Han, J.2
Adam, B.-L.3
Colburn, N.H.4
Wang, M.-H.5
Dong, Z.6
Eizirik, D.L.7
She, J.-X.8
Wang, C.-Y.9
-
72
-
-
3543046736
-
A functional variant of SUMO4, a new IκBα modifier, is associated with type diabetes
-
DOI 10.1038/ng1391
-
Guo, D., M. Li, Y. Zhang, P. Yang, S. Eckenrode, D. Hopkins, W. Zheng, S. Purohit, R. H. Podolsky, A. Muir, J. Wang, Z. Dong, T. Brusko, M. Atkinson, P. Pozzilli, A. Zeidler, L. J. Raffel, C. O. Jacob, Y. Park, M. Serrano-Rios, M. T. Larrad, Z. Zhang, H. J. Garchon, J. F. Bach, J. I. Rotter, J. X. She & C. Y. Wang: A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Nat Genet, 36, 837-41 (2004) (Pubitemid 39014100)
-
(2004)
Nature Genetics
, vol.36
, Issue.8
, pp. 837-841
-
-
Guo, D.1
Li, M.2
Zhang, Y.3
Yang, P.4
Eckenrode, S.5
Hopkins, D.6
Zheng, W.7
Purohit, S.8
Podolsky, R.H.9
Muir, A.10
Wang, J.11
Dong, Z.12
Brusko, T.13
Atkinson, M.14
Pozzilli, P.15
Zeidler, A.16
Raffel, L.J.17
Jacob, C.O.18
Park, Y.19
Serrano-Rios, M.20
Martinez Larrad, M.T.21
Zhang, Z.22
Garchon, H.-J.23
Bach, J.-F.24
Rotter, J.I.25
She, J.-X.26
Wang, C.-Y.27
more..
-
73
-
-
3042644131
-
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus
-
DOI 10.1074/jbc.M402273200
-
Bohren, K. M., V. Nadkarni, J. H. Song, K. H. Gabbay & D. Owerbach: A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. J Biol Chem, 279, 27233-8 (2004) (Pubitemid 38812561)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.26
, pp. 27233-27238
-
-
Bohren, K.M.1
Nadkarni, V.2
Song, J.H.3
Gabbay, K.H.4
Owerbach, D.5
-
74
-
-
33847142379
-
Overexpression of serine-threonine receptor kinase-associated protein in colorectal cancers
-
DOI 10.1111/j.1440-1827.2007.02078.x
-
Kim, C. J., B. J. Choi, J. H. Song, Y. K. Park, Y. G. Cho, S. W. Nam, N. J. Yoo, J. Y. Lee & W. S. Park: Overexpression of serine-threonine receptor kinaseassociated protein in colorectal cancers. Pathol Int, 57, 178-82 (2007) (Pubitemid 46279945)
-
(2007)
Pathology International
, vol.57
, Issue.4
, pp. 178-182
-
-
Kim, C.J.1
Choi, B.J.2
Song, J.H.3
Park, Y.K.4
Cho, Y.G.5
Nam, S.W.6
Yoo, N.J.7
Lee, J.Y.8
Park, W.S.9
-
75
-
-
11144322863
-
STRAP is a strong predictive marker of adjuvant chemotherapy benefit in colorectal cancer
-
DOI 10.1593/neo.04307
-
Buess, M., L. Terracciano, J. Reuter, P. Ballabeni, J. L. Boulay, U. Laffer, U. Metzger, R. Herrmann & C. Rochlitz STRAP is a strong predictive marker of adjuvant chemotherapy benefit in colorectal cancer. Neoplasia, 6, 813-20 (2004) (Pubitemid 40041500)
-
(2004)
Neoplasia
, vol.6
, Issue.6
, pp. 813-820
-
-
Buess, M.1
Terracciano, L.2
Reuter, J.3
Ballabeni, P.4
Boulay, J.-L.5
Laffer, U.6
Metzger, U.7
Herrmann, R.8
Rochlitz, C.9
-
76
-
-
65249138229
-
Tiling path genomic profiling of grade 3 invasive ductal breast cancers
-
Natrajan, R., M. B. Lambros, S. M. Rodriguez-Pinilla, G. Moreno-Bueno, D. S. Tan, C. Marchio, R. Vatcheva, S. Rayter, B. Mahler-Araujo, L. G. Fulford, D. Hungermann, A. Mackay, A. Grigoriadis, K. Fenwick, N. Tamber, D. Hardisson, A. Tutt, J. Palacios, C. J. Lord, H. Buerger, A. Ashworth & J. S. Reis-Filho: Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clin Cancer Res, 15, 2711-22 (2009)
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2711-2722
-
-
Natrajan, R.1
Lambros, M.B.2
Rodriguez-Pinilla, S.M.3
Moreno-Bueno, G.4
Tan, D.S.5
Marchio, C.6
Vatcheva, R.7
Rayter, S.8
Mahler-Araujo, B.9
Fulford, L.G.10
Hungermann, D.11
MacKay, A.12
Grigoriadis, A.13
Fenwick, K.14
Tamber, N.15
Hardisson, D.16
Tutt, A.17
Palacios, J.18
Lord, C.J.19
Buerger, H.20
Ashworth, A.21
Reis-Filho, J.S.22
more..
-
77
-
-
43049153163
-
DNA copy number alterations and expression of relevant genes in triple-negative breast cancer
-
DOI 10.1002/gcc.20550
-
Han, W., E. M. Jung, J. Cho, J. W. Lee, K. T. Hwang, S. J. Yang, J. J. Kang, J. Y. Bae, Y. K. Jeon, I. A. Park, M. Nicolau, S. S. Jeffrey & D. Y. Noh: DNA copy number alterations and expression of relevant genes in triplenegative breast cancer. Genes Chromosomes Cancer, 47, 490-9 (2008) (Pubitemid 351657184)
-
(2008)
Genes Chromosomes and Cancer
, vol.47
, Issue.6
, pp. 490-499
-
-
Han, W.1
Jung, E.-M.2
Cho, J.3
Jong, W.L.4
Hwang, K.-T.5
Yang, S.-J.6
Jason, J.K.7
Bae, J.-Y.8
Yoon, K.J.9
Park, I.-A.10
Nicolau, M.11
Jeffrey, S.S.12
Noh, D.-Y.13
-
78
-
-
33646873910
-
Analysis of ovarian teratomas for isochromosome 12p: Evidence supporting a dual histogenetic pathway for teratomatous elements
-
DOI 10.1038/modpathol.3800596, PII 3800596
-
Poulos, C., L. Cheng, S. Zhang, D. J. Gersell & T. M. Ulbright: Analysis of ovarian teratomas for isochromosome 12p: evidence supporting a dual histogenetic pathway for teratomatous elements. Mod Pathol, 19, 766-71 (2006) (Pubitemid 43780445)
-
(2006)
Modern Pathology
, vol.19
, Issue.6
, pp. 766-771
-
-
Poulos, C.1
Cheng, L.2
Zhang, S.3
Gersell, D.J.4
Ulbright, T.M.5
-
79
-
-
0031877296
-
Triple-color FISH analysis of 12p amplification in testicular germ-cell tumors using 12p band-specific painting probes
-
DOI 10.1007/s001090050262
-
Henegariu, O., G. H. Vance, D. Heiber, M. Pera & N. A. Heerema: Triple-color FISH analysis of 12p amplification in testicular germ-cell tumors using 12p band-specific painting probes. J Mol Med, 76, 648-55 (1998) (Pubitemid 28361883)
-
(1998)
Journal of Molecular Medicine
, vol.76
, Issue.9
, pp. 648-655
-
-
Henegariu, O.1
Vance, G.H.2
Heiber, D.3
Pera, M.4
Heerema, N.A.5
-
80
-
-
38449092456
-
Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A
-
Low, W. K., Y. Dang, T. Schneider-Poetsch, Z. Shi, N. S. Choi, R. M. Rzasa, H. A. Shea, S. Li, K. Park, G. Ma, D. Romo & J. O. Liu: Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A. Methods Enzymol, 431, 303-24 (2007)
-
(2007)
Methods Enzymol
, vol.431
, pp. 303-324
-
-
Low, W.K.1
Dang, Y.2
Schneider-Poetsch, T.3
Shi, Z.4
Choi, N.S.5
Rzasa, R.M.6
Shea, H.A.7
Li, S.8
Park, K.9
Ma, G.10
Romo, D.11
Liu, J.O.12
-
81
-
-
28444448743
-
Inhibition of eukaryotic translation initiation by the marine natural product pateamine A
-
DOI 10.1016/j.molcel.2005.10.008, PII S1097276505016783
-
Low, W. K., Y. Dang, T. Schneider-Poetsch, Z. Shi, N. S. Choi, W. C. Merrick, D. Romo & J. O. Liu: Inhibition of eukaryotic translation initiation by the marine natural product pateamine A. Mol Cell, 20, 709-22 (2005) (Pubitemid 41740693)
-
(2005)
Molecular Cell
, vol.20
, Issue.5
, pp. 709-722
-
-
Low, W.-K.1
Dang, Y.2
Schneider-Poetsch, T.3
Shi, Z.4
Choi, N.S.5
Merrick, W.C.6
Romo, D.7
Liu, J.O.8
-
82
-
-
66849113670
-
Potent in vitro and in vivo anticancer activities of desmethyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A
-
Kuznetsov, G., Q. Xu, L. Rudolph-Owen, K. Tendyke, J. Liu, M. Towle, N. Zhao, J. Marsh, S. Agoulnik, N. Twine, L. Parent, Z. Chen, J. L. Shie, Y. Jiang, H. Zhang, H. Du, R. Boivin, Y. Wang, D. Romo & B. A. Littlefield: Potent in vitro and in vivo anticancer activities of desmethyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A. Mol Cancer Ther (2009)
-
(2009)
Mol Cancer Ther
-
-
Kuznetsov, G.1
Xu, Q.2
Rudolph-Owen, L.3
Tendyke, K.4
Liu, J.5
Towle, M.6
Zhao, N.7
Marsh, J.8
Agoulnik, S.9
Twine, N.10
Parent, L.11
Chen, Z.12
Shie, J.L.13
Jiang, Y.14
Zhang, H.15
Du, H.16
Boivin, R.17
Wang, Y.18
Romo, D.19
Littlefield, B.A.20
more..
|