Effects of tumor metastasis suppressor gene nm23-H1 on invasion and proliferation of cervical cancer cell lines

Chinese Journal of Cancer

Volumn 28, Issue 7, 2009, Pages

  Yang, Yan ^a   Lu, Shi ^a   Li, Min Fang ^a   Wang, Ze Hua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cell cycle; Cervical cancer; Invasion; nm23 H1; Proliferation; Transfect

Indexed keywords

MESSENGER RNA; NUCLEOSIDE DIPHOSPHATE KINASE A;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; EXPRESSION VECTOR; FLOW CYTOMETRY; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PROTEIN FUNCTION; UTERINE CERVIX CANCER;

EID: 77958596320     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.008.10719     Document Type: Article

References (11)

1. Kim H, Kim W, Lee M, et al. Tumor volume and uterine body invasion assessed by MRI for prediction of outcome in cervical carcinoma treated with concurrent chemotherapy and radiotherapy [J]. Jpn J Clin Oncol, 2007, 37 (11): 858-866.
2. Horak CE, Lee JH, Elkahloun AG, et al. Nm23-Hl suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2 [J]. Cancer Res, 2007, 67(15): 7238-7246.
3. McDermott WG, Boissan M, Lacombe ML, et al. Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth [J]. Clin Exp Metastasis, 2008, 25 (2): 131-138.
4. Luo SG, Wang XZ, Sun XB. The expression of P16 and nm23 in cervical cancer tissue and its clinical significance [J]. Zhonghua Shi Yong Fu Ke He Chan Ke Za Zhi, 2004, 20(7): 421-422. [in Chinese]
5. Utrera-Barillas D, Salceda-Vargas M, Gariglio-Vidal P, et al. H-ras and Nm23-H1 gene expression and proteolytic activity in squamous carcinoma of the uterine cervix [J]. Arch Med Res, 2000, 31(2): 172-181.
6. Che GW, Zhou QH, Zhu W, et al. The molecular mechanism of nm23-H1 gene which reverse the metastasis phenotype of human small cell lung cancer cell line L9981 [J]. Ai Zheng, 2005, 24(3): 278-284.[in Chinese]
7. Palmieri D, Halverson DO, Ouatas T, et al. Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer [J]. J Natl Cancer Inst, 2005, 97(9): 632-642.
8. Tseng YH, Vicent D, Zhu J, et al. Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23 [J]. Cancer Res, 2001, 61 (5): 2071-2079.
9. Valentjn LJ, Koppen A, van Asperen R, et al. Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, Cdc42, and nm23 genes [J]. Cancer Res, 2005, 65(8): 3136-3145.
10. Chao A, Wang TH, Lee YS, et al. Molecular characterization of adenocarcinoma and squamous carcinoma of the uterine cervix using microarray analysis of gene expression [J]. Int J Cancer, 2006, 119(1): 91-98.
11. Eifel PJ, Burke TW, Morris M, et al. Adenocarcinoma as an independent risk factor for disease recurrence in patients with stage IB cervical carcinoma [J]. Gynecol Oncol, 1995, 59 (1): 38-44.