-
1
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells
-
Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH (1997) Viable offspring derived from fetal and adult mammalian cells. Nature 385, 810-813.
-
(1997)
Nature
, vol.385
, pp. 810-813
-
-
Wilmut, I.1
Schnieke, A.E.2
McWhir, J.3
Kind, A.J.4
Campbell, K.H.5
-
3
-
-
0035810169
-
Can they rebuild us?
-
Aldhous P (2001) Can they rebuild us? Nature 410, 622-625.
-
(2001)
Nature
, vol.410
, pp. 622-625
-
-
Aldhous, P.1
-
4
-
-
36549033276
-
Producing primate embryonic stem cells by somatic nuclear transfer
-
Byrne JA, Pedersen DA, Clepper LL, Nelson M, Sanger WG, Gokhale S et al. (2007) Producing primate embryonic stem cells by somatic nuclear transfer. Nature 450, 497-502.
-
(2007)
Nature
, vol.450
, pp. 497-502
-
-
Byrne, J.A.1
Pedersen, D.A.2
Clepper, L.L.3
Nelson, M.4
Sanger, W.G.5
Gokhale, S.6
-
5
-
-
67649573995
-
Epigenetic reprogramming by somatic cell nuclear transfer in primates
-
Sparman M, Dighe V, Sritanaudomchai H, Ma H, Ramsey C, Pedersen D et al. (2009) Epigenetic reprogramming by somatic cell nuclear transfer in primates. Stem Cells 27, 1255-1264.
-
(2009)
Stem Cells
, vol.27
, pp. 1255-1264
-
-
Sparman, M.1
Dighe, V.2
Sritanaudomchai, H.3
Ma, H.4
Ramsey, C.5
Pedersen, D.6
-
6
-
-
20544451854
-
Patient-specific embryonic stem-cells derived from human SCNT blastocysts
-
Hwang WS, Roh SI, Lee BC, Kang SK, Kwon DK, Kim S et al. (2005) Patient-specific embryonic stem-cells derived from human SCNT blastocysts. Science 308, 1777-1783.
-
(2005)
Science
, vol.308
, pp. 1777-1783
-
-
Hwang, W.S.1
Roh, S.I.2
Lee, B.C.3
Kang, S.K.4
Kwon, D.K.5
Kim, S.6
-
7
-
-
23144435170
-
Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes
-
Stojkovic M, Stojkovic P, Leary C, Hall VJ, Armstrong L, Herbert M et al. (2005) Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes. Reprod. Biomed. Online 11, 226-231.
-
(2005)
Reprod. Biomed. Online
, vol.11
, pp. 226-231
-
-
Stojkovic, M.1
Stojkovic, P.2
Leary, C.3
Hall, V.J.4
Armstrong, L.5
Herbert, M.6
-
8
-
-
39449113141
-
Development of human cloned blastocysts following somatic cell nuclear transfer (SCNT) with adult fibroblasts
-
French AJ, Adams CA, Anderson LS, Kirchen JR, Hughes MR, Wood SH (2008) Development of human cloned blastocysts following somatic cell nuclear transfer (SCNT) with adult fibroblasts. Stem Cells 26, 485-493.
-
(2008)
Stem Cells
, vol.26
, pp. 485-493
-
-
French, A.J.1
Adams, C.A.2
Anderson, L.S.3
Kirchen, J.R.4
Hughes, M.R.5
Wood, S.H.6
-
9
-
-
62349130208
-
Human embryos derived by somatic cell nuclear transfer using an alternative enucleation approach
-
Li J, Liu X, Wang H, Zhang S, Liu F, Wang X et al. (2009b) Human embryos derived by somatic cell nuclear transfer using an alternative enucleation approach. Cloning Stem Cells 11, 39-50.
-
(2009)
Cloning Stem Cells
, vol.11
, pp. 39-50
-
-
Li, J.1
Liu, X.2
Wang, H.3
Zhang, S.4
Liu, F.5
Wang, X.6
-
10
-
-
33749675665
-
Egg harvesting for stem cell research: medical risks and ethical problems
-
Beeson D, Lippman A (2006) Egg harvesting for stem cell research: medical risks and ethical problems. Reprod. Biomed. Online 13, 573-579.
-
(2006)
Reprod. Biomed. Online
, vol.13
, pp. 573-579
-
-
Beeson, D.1
Lippman, A.2
-
11
-
-
45149085466
-
Egg shortage hits race to clone human stem cells
-
Maher B (2008) Egg shortage hits race to clone human stem cells. Nature 453, 828-829.
-
(2008)
Nature
, vol.453
, pp. 828-829
-
-
Maher, B.1
-
12
-
-
0034722999
-
The ethical validity of using nuclear transfer in human transplantation
-
Lanza RP, Caplan AL, Silver LM, Cibelli JB, West MD, Green RM (2000) The ethical validity of using nuclear transfer in human transplantation. JAMA 284, 3175-3179.
-
(2000)
JAMA
, vol.284
, pp. 3175-3179
-
-
Lanza, R.P.1
Caplan, A.L.2
Silver, L.M.3
Cibelli, J.B.4
West, M.D.5
Green, R.M.6
-
13
-
-
0242360387
-
-
The Report of The President's Council on Bioethics, Public Affairs, New York.
-
Kass LR, Human Cloning and Human Dignity, The Report of The President's Council on Bioethics, 2002, Public Affairs, New York, p. 53.
-
(2002)
Human Cloning and Human Dignity
, pp. 53
-
-
Kass, L.R.1
-
14
-
-
11144219959
-
Human cloning - the science and ethics of nuclear transplantation
-
Jaenisch R (2004) Human cloning - the science and ethics of nuclear transplantation. N. Engl. J. Med. 351, 2787-2791.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2787-2791
-
-
Jaenisch, R.1
-
15
-
-
3142702897
-
Zygote and "clonote"- the ethical use of embryonic stem cells
-
McHugh PR (2004) Zygote and "clonote"- the ethical use of embryonic stem cells. N. Engl. J. Med. 351, 209-211.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 209-211
-
-
McHugh, P.R.1
-
16
-
-
0030947098
-
Clone mammals...clone man?
-
Kahn A (1997a) Clone mammals...clone man? Nature 336, 119.
-
(1997)
Nature
, vol.336
, pp. 119
-
-
Kahn, A.1
-
17
-
-
0030844523
-
Cloning, dignity and ethical revisionism
-
Kahn A (1997b) Cloning, dignity and ethical revisionism. Nature 388, 320.
-
(1997)
Nature
, vol.388
, pp. 320
-
-
Kahn, A.1
-
18
-
-
34547625273
-
Interspecies somatic cell nuclear transfer and preliminary data for horse-cow/mouse iSCNT
-
Tecirlioglu RT, Guo J, Trounson AO (2006) Interspecies somatic cell nuclear transfer and preliminary data for horse-cow/mouse iSCNT. Stem Cell Rev. 2, 277-287.
-
(2006)
Stem Cell Rev.
, vol.2
, pp. 277-287
-
-
Tecirlioglu, R.T.1
Guo, J.2
Trounson, A.O.3
-
19
-
-
34548319084
-
Human-animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate
-
St John J, Lovell-Badge R (2007) Human-animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate. Nat. Cell Biol. 9, 988-992.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 988-992
-
-
St John, J.1
Lovell-Badge, R.2
-
21
-
-
0032764950
-
Prospect for the use of nuclear transfer in human transplantation
-
Lanza RP, Cibelli JB, West MD (1999b) Prospect for the use of nuclear transfer in human transplantation. Nat. Biotechnol. 17, 1171-1174.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 1171-1174
-
-
Lanza, R.P.1
Cibelli, J.B.2
West, M.D.3
-
22
-
-
0348110638
-
Blastocyst formation, karyotype, and mitochondrial DNA of interspecies embryos derived from nuclear transfer of human cord fibroblasts into enucleated bovine embryos
-
Chang KH, Lim JM, Kang SK, Lee BC, Moon SY, Hwang WS (2003) Blastocyst formation, karyotype, and mitochondrial DNA of interspecies embryos derived from nuclear transfer of human cord fibroblasts into enucleated bovine embryos. Fertil. Steril. 80, 380-1387.
-
(2003)
Fertil. Steril.
, vol.80
, pp. 380-1387
-
-
Chang, K.H.1
Lim, J.M.2
Kang, S.K.3
Lee, B.C.4
Moon, S.Y.5
Hwang, W.S.6
-
23
-
-
5144226489
-
An optimized protocol of a human-to-cattle interspecies somatic cell nuclear transfer
-
Chang KH, Lim JM, Kang SK, Lee BC, Moon SY, Hwang WS (2004) An optimized protocol of a human-to-cattle interspecies somatic cell nuclear transfer. Fertil. Steril. 82, 960-962.
-
(2004)
Fertil. Steril.
, vol.82
, pp. 960-962
-
-
Chang, K.H.1
Lim, J.M.2
Kang, S.K.3
Lee, B.C.4
Moon, S.Y.5
Hwang, W.S.6
-
24
-
-
33645738693
-
Evaluation of the embryonic preimplantation potential of human adult somatic cells via an embryo interspecies bioassay using bovine oocytes
-
Illmensee K, Levanduski M, Zavos PM (2006) Evaluation of the embryonic preimplantation potential of human adult somatic cells via an embryo interspecies bioassay using bovine oocytes. Fertil. Steril. 85(Suppl. 1), 1248-1261.
-
(2006)
Fertil. Steril.
, vol.85
, Issue.SUPPL. 1
, pp. 1248-1261
-
-
Illmensee, K.1
Levanduski, M.2
Zavos, P.M.3
-
25
-
-
79953842690
-
Britain gets hybrid embryo go-ahead. Human-animal embryos given green light after public backing
-
doi: 10.1038/news070903-12.
-
Hopkin M (2007) Britain gets hybrid embryo go-ahead. Human-animal embryos given green light after public backing. Nature News doi: 10.1038/news070903-12.
-
(2007)
Nature News
-
-
Hopkin, M.1
-
26
-
-
79953882758
-
-
HFEA, HFEA statement on its decision regarding hybrid embryos, Available at (accessed 5 September 2007).
-
HFEA (2007) HFEA statement on its decision regarding hybrid embryos, Available at (accessed 5 September 2007).
-
(2007)
-
-
-
27
-
-
85047692551
-
Embryonic death and the creation of human embryonic stem cells
-
Landry DW, Zucker HA (2004) Embryonic death and the creation of human embryonic stem cells. J. Clin. Invest. 114, 1184-1186.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1184-1186
-
-
Landry, D.W.1
Zucker, H.A.2
-
28
-
-
0037197972
-
From intestine to muscle: nuclear reprogramming through defective cloned embryos
-
Byrne JA, Simonsson S, Gurdon JB (2002) From intestine to muscle: nuclear reprogramming through defective cloned embryos. Proc. Natl. Acad. Sci. USA 99, 6059-6063.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6059-6063
-
-
Byrne, J.A.1
Simonsson, S.2
Gurdon, J.B.3
-
30
-
-
10744223967
-
Human embryonic stem cell lines from discarded embryos
-
Mitalipova M, Cahoun J, Shin S, Wininger D, Schultz T, Noggle S et al. (2003) Human embryonic stem cell lines from discarded embryos. Stem Cells 21, 521-526.
-
(2003)
Stem Cells
, vol.21
, pp. 521-526
-
-
Mitalipova, M.1
Cahoun, J.2
Shin, S.3
Wininger, D.4
Schultz, T.5
Noggle, S.6
-
31
-
-
0141891304
-
Preimplantation genetic diagnosis as a novel source of embryos for stem cell research
-
Pickering SJ, Braude PR, Patel M, Burns CJ, Trussler J, Bolton V et al. (2003) Preimplantation genetic diagnosis as a novel source of embryos for stem cell research. Reprod. Biomed. Online 7, 353-364.
-
(2003)
Reprod. Biomed. Online
, vol.7
, pp. 353-364
-
-
Pickering, S.J.1
Braude, P.R.2
Patel, M.3
Burns, C.J.4
Trussler, J.5
Bolton, V.6
-
32
-
-
25144500251
-
The derivation of two additional human embryonic stem cell lines from day 3 embryos with low morphological scores
-
Chen H, Qian K, Hu J, Liu D, Lu W, Yang Y et al. (2005a) The derivation of two additional human embryonic stem cell lines from day 3 embryos with low morphological scores. Hum. Reprod. 20, 2201-2206.
-
(2005)
Hum. Reprod.
, vol.20
, pp. 2201-2206
-
-
Chen, H.1
Qian, K.2
Hu, J.3
Liu, D.4
Lu, W.5
Yang, Y.6
-
33
-
-
33846044682
-
Derivation of human embryonic stem cells from developing and arrested embryos
-
Zhang X, Stojkovic P, Przyborski S, Cooke M, Armstrong L, Lako M et al. (2006) Derivation of human embryonic stem cells from developing and arrested embryos. Stem Cells 24, 2669-2676.
-
(2006)
Stem Cells
, vol.24
, pp. 2669-2676
-
-
Zhang, X.1
Stojkovic, P.2
Przyborski, S.3
Cooke, M.4
Armstrong, L.5
Lako, M.6
-
34
-
-
38949199410
-
Human embryonic stem cell derivation from poor-quality embryos
-
Lerou PH, Yabuuchi A, Huo H, Takeuchi A, Shea J, Cimini C (2008) Human embryonic stem cell derivation from poor-quality embryos. Nat. Biotechnol. 26, 212-214.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 212-214
-
-
Lerou, P.H.1
Yabuuchi, A.2
Huo, H.3
Takeuchi, A.4
Shea, J.5
Cimini, C.6
-
35
-
-
33750122465
-
Scientists create human stem cell line from "dead" embryos
-
Holden C (2006) Scientists create human stem cell line from "dead" embryos. Science 313, 1869.
-
(2006)
Science
, vol.313
, pp. 1869
-
-
Holden, C.1
-
36
-
-
2342468747
-
Mice without a father
-
Loebel DAF, Tam PPL (2004) Mice without a father. Nature 428, 809-811.
-
(2004)
Nature
, vol.428
, pp. 809-811
-
-
Loebel, D.A.F.1
Tam, P.P.L.2
-
37
-
-
0021067190
-
Development of gynogenetic eggs in the mouse: implications for parthenogenetic embryos
-
Surani MA, Barton SC (1983) Development of gynogenetic eggs in the mouse: implications for parthenogenetic embryos. Science 222, 1034-1036.
-
(1983)
Science
, vol.222
, pp. 1034-1036
-
-
Surani, M.A.1
Barton, S.C.2
-
38
-
-
0036468415
-
Parthenogenetic stem cells in nonhuman primates
-
Cibelli JB, Grant KA, Chapman KB, Cunniff K, Worst T, Green HL et al. (2002) Parthenogenetic stem cells in nonhuman primates. Science 295, 819.
-
(2002)
Science
, vol.295
, pp. 819
-
-
Cibelli, J.B.1
Grant, K.A.2
Chapman, K.B.3
Cunniff, K.4
Worst, T.5
Green, H.L.6
-
39
-
-
0036515654
-
The genesis of embryonic stem cells. Does parthenogenesis offer a more promising means of developing immune-matched ES cells
-
Trounson A (2002) The genesis of embryonic stem cells. Does parthenogenesis offer a more promising means of developing immune-matched ES cells. Nat. Biotechnol. 20, 237-238.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 237-238
-
-
Trounson, A.1
-
40
-
-
0034968047
-
Parthenogenetic activation of rhesus monkey oocytes and reconstructed embryos
-
Mitalipov SM, Nusser KD, Wolf DP (2001) Parthenogenetic activation of rhesus monkey oocytes and reconstructed embryos. Biol. Reprod. 65, 253-259.
-
(2001)
Biol. Reprod.
, vol.65
, pp. 253-259
-
-
Mitalipov, S.M.1
Nusser, K.D.2
Wolf, D.P.3
-
41
-
-
0141483048
-
Nonhuman primate parthenogenetic stem cells
-
Vrana KE, Hipp JD, Goss AM, McCool BA, Riddle DR, Walker SJ et al. (2003) Nonhuman primate parthenogenetic stem cells. Proc. Natl. Acad. Sci. USA 100(Suppl. 1), 11911-11916.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.SUPPL. 1
, pp. 11911-11916
-
-
Vrana, K.E.1
Hipp, J.D.2
Goss, A.M.3
McCool, B.A.4
Riddle, D.R.5
Walker, S.J.6
-
42
-
-
0037224445
-
Multilineage potential of homozygous stem cells derived from metaphase II oocytes
-
Lin H, Lei JQ, Wininger D, Nguyen MT, Khanna R, Hartmann C et al. (2003) Multilineage potential of homozygous stem cells derived from metaphase II oocytes. Stem Cells 21, 152-161.
-
(2003)
Stem Cells
, vol.21
, pp. 152-161
-
-
Lin, H.1
Lei, J.Q.2
Wininger, D.3
Nguyen, M.T.4
Khanna, R.5
Hartmann, C.6
-
43
-
-
37349082838
-
Parthenotes as a source of embryonic stem cells
-
Brevini TA, Gandolfi F (2008) Parthenotes as a source of embryonic stem cells. Cell Prolif. 41(Suppl. 1), 20-30.
-
(2008)
Cell Prolif.
, vol.41
, Issue.SUPPL. 1
, pp. 20-30
-
-
Brevini, T.A.1
Gandolfi, F.2
-
44
-
-
37149036248
-
A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure
-
Lin G, OuYang Q, Zhou X, Gu Y, Yuan D, Li W et al. (2007) A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res. 17, 999-1007.
-
(2007)
Cell Res.
, vol.17
, pp. 999-1007
-
-
Lin, G.1
OuYang, Q.2
Zhou, X.3
Gu, Y.4
Yuan, D.5
Li, W.6
-
45
-
-
37149049044
-
Derivation of human embryonic stem cell lines from parthenogenic blastocysts
-
Mai Q, Yy Y, Li T, Wang L, Chen MJ, Huang SZ et al. (2007) Derivation of human embryonic stem cell lines from parthenogenic blastocysts. Cell Res. 17, 1008-1019.
-
(2007)
Cell Res.
, vol.17
, pp. 1008-1019
-
-
Mai, Q.1
Yy, Y.2
Li, T.3
Wang, L.4
Chen, M.J.5
Huang, S.Z.6
-
46
-
-
39449099453
-
Patient-specific stem cell lines derived from human parthenogenetic blastocysts
-
Revazova ES, Turovets NA, Kochetkova OD, Kindarova LB, Kuzmichev LN, Janus JD et al. (2007) Patient-specific stem cell lines derived from human parthenogenetic blastocysts. Cloning Stem Cells 9, 432-449.
-
(2007)
Cloning Stem Cells
, vol.9
, pp. 432-449
-
-
Revazova, E.S.1
Turovets, N.A.2
Kochetkova, O.D.3
Kindarova, L.B.4
Kuzmichev, L.N.5
Janus, J.D.6
-
47
-
-
40349103721
-
HLA homozygous stem cell lines derived from human parthenogenetic blastocysts
-
Revazova ES, Turovets NA, Kochetkova OD, Agapova Ls, Sebastian JL, Pryzhkova MV et al. (2008) HLA homozygous stem cell lines derived from human parthenogenetic blastocysts. Cloning Stem Cells 10, 11-24.
-
(2008)
Cloning Stem Cells
, vol.10
, pp. 11-24
-
-
Revazova, E.S.1
Turovets, N.A.2
Kochetkova, O.D.3
Agapova, L.4
Sebastian, J.L.5
Pryzhkova, M.V.6
-
48
-
-
44449094118
-
In vivo and in vitro differentiation of uniparental embryonic stem cells into hematopoietic and neural cell types
-
Eckardt S, Dinger TC, Kurosaka S, Leu NA, Müller AM, McLaughlin KJ (2008) In vivo and in vitro differentiation of uniparental embryonic stem cells into hematopoietic and neural cell types. Organogenesis 4, 33-41.
-
(2008)
Organogenesis
, vol.4
, pp. 33-41
-
-
Eckardt, S.1
Dinger, T.C.2
Kurosaka, S.3
Leu, N.A.4
Müller, A.M.5
McLaughlin, K.J.6
-
49
-
-
58049201830
-
Parthenogenesis-derived multipotent stem cells adapted for tissue engineering applications
-
Koh CJ, Delo DM, Lee JW, Siddiqui MM, Lanza RP, Soker S et al. (2009) Parthenogenesis-derived multipotent stem cells adapted for tissue engineering applications. Methods 47, 90-97.
-
(2009)
Methods
, vol.47
, pp. 90-97
-
-
Koh, C.J.1
Delo, D.M.2
Lee, J.W.3
Siddiqui, M.M.4
Lanza, R.P.5
Soker, S.6
-
50
-
-
49449109011
-
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease
-
Sanchez-Pernaute R, Lee H, Patterson M, Reske-Nielsen C, Yoshizaki T, Sonntag KC et al. (2008) Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. Brain 131, 2127-2139.
-
(2008)
Brain
, vol.131
, pp. 2127-2139
-
-
Sanchez-Pernaute, R.1
Lee, H.2
Patterson, M.3
Reske-Nielsen, C.4
Yoshizaki, T.5
Sonntag, K.C.6
-
51
-
-
64949163398
-
Change in gene expression of mouse embryonic stem cells derived from parthenogenetic activation
-
Gong SP, Kim H, Lee EJ, Lee ST, Moon S, Lee HJ et al. (2009) Change in gene expression of mouse embryonic stem cells derived from parthenogenetic activation. Hum. Reprod. 24, 805-814.
-
(2009)
Hum. Reprod.
, vol.24
, pp. 805-814
-
-
Gong, S.P.1
Kim, H.2
Lee, E.J.3
Lee, S.T.4
Moon, S.5
Lee, H.J.6
-
52
-
-
66149098148
-
Correlation of expression and methylation of imprinted genes with pluripotency of parthenogenetic embryonic stem cells
-
Li C, Chen Z, Liu Z, Huang J, Zhang W, Zhou L et al. (2009a) Correlation of expression and methylation of imprinted genes with pluripotency of parthenogenetic embryonic stem cells. Hum. Mol. Genet. 18, 2177-2187.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2177-2187
-
-
Li, C.1
Chen, Z.2
Liu, Z.3
Huang, J.4
Zhang, W.5
Zhou, L.6
-
53
-
-
34548623214
-
Activation of paternally expressed imprinted genes in newly derived germline-competent mouse parthenogenetic embryonic stem cell lines
-
Jiang H, Sun B, Wang H, Zhang Z, Gao F, Shi G et al. (2007) Activation of paternally expressed imprinted genes in newly derived germline-competent mouse parthenogenetic embryonic stem cell lines. Cell Res. 17, 792-803.
-
(2007)
Cell Res.
, vol.17
, pp. 792-803
-
-
Jiang, H.1
Sun, B.2
Wang, H.3
Zhang, Z.4
Gao, F.5
Shi, G.6
-
54
-
-
0042468975
-
The science and ethics of parthenogenesis
-
Latkovic MS (2002) The science and ethics of parthenogenesis. Natl. Cathol. Bioeth. Q. 2, 245-255.
-
(2002)
Natl. Cathol. Bioeth. Q.
, vol.2
, pp. 245-255
-
-
Latkovic, M.S.1
-
55
-
-
17744369076
-
-
Altered Nuclear Transfer as a Morally Acceptable Means for the Procurement of Human Embryonic stem cells, commissioned working paper discussed at the Council's December 2004 meeting, The President's Council on Bioethics, Available at reprinted in Perspectives in Biology and Medicine,. number 2, spring 2005
-
Hurlbut WB (2004) Altered Nuclear Transfer as a Morally Acceptable Means for the Procurement of Human Embryonic stem cells, commissioned working paper discussed at the Council's December 2004 meeting, The President's Council on Bioethics, Available at reprinted in Perspectives in Biology and Medicine, vol. 48, number 2, spring 2005, pp.211-228.
-
(2004)
, vol.48
, pp. 211-228
-
-
Hurlbut, W.B.1
-
56
-
-
21744459567
-
Altered nuclear transfer as a morally acceptable means for the procurement of human embryonic stem cell
-
Hurlbut WB (2005a) Altered nuclear transfer as a morally acceptable means for the procurement of human embryonic stem cell. Natl. Cathol. Bioeth. Q. 5, 145-151.
-
(2005)
Natl. Cathol. Bioeth. Q.
, vol.5
, pp. 145-151
-
-
Hurlbut, W.B.1
-
57
-
-
17744369076
-
Altered nuclear transfer as a morally acceptable means for the procurement of human embryonic stem cells
-
Hurlbut WB (2005b) Altered nuclear transfer as a morally acceptable means for the procurement of human embryonic stem cells. Perspect. Biol. Med. 48, 211-228.
-
(2005)
Perspect. Biol. Med.
, vol.48
, pp. 211-228
-
-
Hurlbut, W.B.1
-
58
-
-
23044488875
-
Altered embryos offered as solution to stem-cell rift
-
Check E (2005a) Altered embryos offered as solution to stem-cell rift. Nature 436, 309.
-
(2005)
Nature
, vol.436
, pp. 309
-
-
Check, E.1
-
59
-
-
33144463121
-
Cdx2 gene expression and trophectoderm lineage specification in mouse embryos
-
Deb K, Sivaguru M, Yong HY, Roberts RM (2006) Cdx2 gene expression and trophectoderm lineage specification in mouse embryos. Science 311, 992-996.
-
(2006)
Science
, vol.311
, pp. 992-996
-
-
Deb, K.1
Sivaguru, M.2
Yong, H.Y.3
Roberts, R.M.4
-
60
-
-
70349782291
-
CDX2 in the formation of the trophectoderm lineage in primate embryos
-
Sritanaudomchal H, Sparman M, Tachibana M, Clepper L, Woodward J, Gokhale S et al. (2009) CDX2 in the formation of the trophectoderm lineage in primate embryos. Dev. Biol. 335, 179-187.
-
(2009)
Dev. Biol.
, vol.335
, pp. 179-187
-
-
Sritanaudomchal, H.1
Sparman, M.2
Tachibana, M.3
Clepper, L.4
Woodward, J.5
Gokhale, S.6
-
61
-
-
14944374000
-
Altered nuclear transfer
-
Hurlbut WB (2005c) Altered nuclear transfer. N. Engl. J. Med. 352, 1153-1154.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1153-1154
-
-
Hurlbut, W.B.1
-
62
-
-
30544449468
-
Generation of nuclear transfer-derived pluripotent ES cells from cloned cdx2-deficient blastocysts
-
Meissner A, Jaenisch R (2006) Generation of nuclear transfer-derived pluripotent ES cells from cloned cdx2-deficient blastocysts. Nature 439, 212-215.
-
(2006)
Nature
, vol.439
, pp. 212-215
-
-
Meissner, A.1
Jaenisch, R.2
-
63
-
-
11144223547
-
Altered nuclear transfer in stem-cell research - a flawed proposal
-
Melton DA, Daley GQ, Jennings CG (2004) Altered nuclear transfer in stem-cell research - a flawed proposal. N. Engl. J. Med. 351, 2791.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2791
-
-
Melton, D.A.1
Daley, G.Q.2
Jennings, C.G.3
-
64
-
-
0036716876
-
Homeobox genes in gut development
-
Beck F (2002) Homeobox genes in gut development. Gut 51, 450-454.
-
(2002)
Gut
, vol.51
, pp. 450-454
-
-
Beck, F.1
-
65
-
-
24344436804
-
Embryo's moral status is unaffected by alteration
-
Turnpenny L (2005) Embryo's moral status is unaffected by alteration. Nature 437, 26.
-
(2005)
Nature
, vol.437
, pp. 26
-
-
Turnpenny, L.1
-
66
-
-
22144487740
-
Embryo-free techniques gain momentum
-
Vogel G (2005) Embryo-free techniques gain momentum. Science 309, 240-241.
-
(2005)
Science
, vol.309
, pp. 240-241
-
-
Vogel, G.1
-
67
-
-
12544257052
-
The stem cell pluripotency factor NANOG activates transcription with two unusual point subdomains at its C terminus
-
Pan G, Pei D (2005) The stem cell pluripotency factor NANOG activates transcription with two unusual point subdomains at its C terminus. J. Biol. Chem. 280, 1401-1407.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1401-1407
-
-
Pan, G.1
Pei, D.2
-
68
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell, 122, 1-10.
-
(2005)
Cell
, vol.122
, pp. 1-10
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
Zucker, J.P.6
-
69
-
-
32944457696
-
Why human "altered nuclear transfer" is un a holistic systems view
-
Byrnes WM (2005) Why human "altered nuclear transfer" is unethical. a holistic systems view. Natl. Cathol. Bioeth. Q. 5, 271-279.
-
(2005)
Natl. Cathol. Bioeth. Q.
, vol.5
, pp. 271-279
-
-
Byrnes, W.M.1
-
70
-
-
0032506231
-
Derivation of pluripotent stem cells from cultured human primordial germ cells
-
Schamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ et al. (1998) Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc. Natl. Acad. Sci. USA 95, 13726-13731.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13726-13731
-
-
Schamblott, M.J.1
Axelman, J.2
Wang, S.3
Bugg, E.M.4
Littlefield, J.W.5
Donovan, P.J.6
-
71
-
-
0345688817
-
Derivation of human embryonic germ cells: an alternative source of pluripotent cells
-
Turnpenny L, Brickwood S, Spalluto CM, Piper K, Cameron IT, Wilson DI et al. (2003) Derivation of human embryonic germ cells: an alternative source of pluripotent cells. Stem Cells 21, 598-609.
-
(2003)
Stem Cells
, vol.21
, pp. 598-609
-
-
Turnpenny, L.1
Brickwood, S.2
Spalluto, C.M.3
Piper, K.4
Cameron, I.T.5
Wilson, D.I.6
-
72
-
-
79953837574
-
Examination of individual blastomeres as a source of stem cells, Session 04, Stem Cells, Abstract O-018, p.i7, Abstracts of the 21st Annual Meeting of the European Society of Human Reproduction and Embryology, Copenhagen, Denmark, 19-22 June 2005
-
Baha A, Takeuchi T, Tanaka N, Neri QV, Rosenwaks Z, Palermo GD (2005) Examination of individual blastomeres as a source of stem cells, Session 04, Stem Cells, Abstract O-018, p.i7, Abstracts of the 21st Annual Meeting of the European Society of Human Reproduction and Embryology, Copenhagen, Denmark, 19-22 June 2005. Hum. Reprod., 20(Suppl. 1), i7.
-
(2005)
Hum. Reprod.
, vol.20
, Issue.SUPPL. 1
-
-
Baha, A.1
Takeuchi, T.2
Tanaka, N.3
Neri, Q.V.4
Rosenwaks, Z.5
Palermo, G.D.6
-
73
-
-
23944482247
-
Identification and isolation of embryonic stem cells in reproductive endocrinology: theoretical protocols for conservation of human embryos derived from in vitro fertilization
-
Sills ES, Takeuchi T, Tanaka N, Neri QV, Palermo GD (2005) Identification and isolation of embryonic stem cells in reproductive endocrinology: theoretical protocols for conservation of human embryos derived from in vitro fertilization. Theor. Biol. Med. Model. 2, 25 (1-8).
-
(2005)
Theor. Biol. Med. Model.
, vol.2
, Issue.1-8
, pp. 25
-
-
Sills, E.S.1
Takeuchi, T.2
Tanaka, N.3
Neri, Q.V.4
Palermo, G.D.5
-
74
-
-
34147155348
-
Efficient establishment of mouse embryonic stem cell lines from single blastomeres and polar bodies
-
Wakayama S, Hikichi T, Suetsugu R, Sakaide Y, Bul HT, Mizutani E et al. (2007) Efficient establishment of mouse embryonic stem cell lines from single blastomeres and polar bodies. Stem Cells 25, 986-993.
-
(2007)
Stem Cells
, vol.25
, pp. 986-993
-
-
Wakayama, S.1
Hikichi, T.2
Suetsugu, R.3
Sakaide, Y.4
Bul, H.T.5
Mizutani, E.6
-
75
-
-
33748580104
-
Human embryonic stem cell lines derived from single blastomeres
-
Klimanskaya I, Chung Y, Becker S, Lu SJ, Lanza R (2006) Human embryonic stem cell lines derived from single blastomeres. Nature 444, 481-485.
-
(2006)
Nature
, vol.444
, pp. 481-485
-
-
Klimanskaya, I.1
Chung, Y.2
Becker, S.3
Lu, S.J.4
Lanza, R.5
-
76
-
-
38649093350
-
Human embryonic stem cell lines generated without embryo destruction
-
Chung Y, Klimanskaya I, Becker S, Li T, Maserati M, Lu SJ et al. (2008) Human embryonic stem cell lines generated without embryo destruction. Cell Stem Cell 2, 113-117.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 113-117
-
-
Chung, Y.1
Klimanskaya, I.2
Becker, S.3
Li, T.4
Maserati, M.5
Lu, S.J.6
-
77
-
-
70350503771
-
Human embryonic stem cell lines derived from single blastomeres of two 4-cell stage embryos
-
Geens M, Mateizel I, Sermon K, de Rycke M, Spits C, Cauffman G et al. (2009) Human embryonic stem cell lines derived from single blastomeres of two 4-cell stage embryos. Hum. Reprod. 24, 2709-2717.
-
(2009)
Hum. Reprod.
, vol.24
, pp. 2709-2717
-
-
Geens, M.1
Mateizel, I.2
Sermon, K.3
de Rycke, M.4
Spits, C.5
Cauffman, G.6
-
78
-
-
52749091617
-
Derivation of the first Swiss human embryonic stem cell line from a single blastomere of an arrested four-cell stage embryo
-
Feki A, Bosman A, Dubuisson JB, Irion O, Dahoun S, Pelte MF et al. (2008) Derivation of the first Swiss human embryonic stem cell line from a single blastomere of an arrested four-cell stage embryo. Swiss Med. Wkly. 138, 540-550.
-
(2008)
Swiss Med. Wkly.
, vol.138
, pp. 540-550
-
-
Feki, A.1
Bosman, A.2
Dubuisson, J.B.3
Irion, O.4
Dahoun, S.5
Pelte, M.F.6
-
79
-
-
62549153326
-
A human embryonic stem cell line derived from a single blastomere of a 4-cell stage embryo, Abstract of the 24th Meeting of the ESHRE, Barcelona, Spain, 7-9 July 2008
-
Abstract 0/274.
-
Van de Velde H, Geens M, Mateizei I, Spits C, Sermon K, de Rycke M et al. (2008) A human embryonic stem cell line derived from a single blastomere of a 4-cell stage embryo, Abstract of the 24th Meeting of the ESHRE, Barcelona, Spain, 7-9 July 2008. Hum. Reprod. 23(Suppl. 1), i110. Abstract 0/274.
-
(2008)
Hum. Reprod.
, vol.23
, Issue.SUPPL. 1
-
-
Van de Velde, H.1
Geens, M.2
Mateizei, I.3
Spits, C.4
Sermon, K.5
de Rycke, M.6
-
80
-
-
30544453798
-
Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres
-
Chung Y, Klimanskaya I, Becker S, Marh J, Lu SJ, Johnson J et al. (2006) Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres. Nature 439, 216-219.
-
(2006)
Nature
, vol.439
, pp. 216-219
-
-
Chung, Y.1
Klimanskaya, I.2
Becker, S.3
Marh, J.4
Lu, S.J.5
Johnson, J.6
-
81
-
-
33749335015
-
"Ethical" stem-cell paper under attack
-
Abbott A (2006) "Ethical" stem-cell paper under attack. Nature 443, 12.
-
(2006)
Nature
, vol.443
, pp. 12
-
-
Abbott, A.1
-
82
-
-
0035499457
-
Reprogramming of genome function through epigenetic inheritance
-
Surani MA (2001) Reprogramming of genome function through epigenetic inheritance. Nature 414, 122-128.
-
(2001)
Nature
, vol.414
, pp. 122-128
-
-
Surani, M.A.1
-
83
-
-
23944457397
-
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
-
Cowan CA, Atienza J, Melton DA, Eggan K (2005) Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309, 1369-1373.
-
(2005)
Science
, vol.309
, pp. 1369-1373
-
-
Cowan, C.A.1
Atienza, J.2
Melton, D.A.3
Eggan, K.4
-
84
-
-
30944436674
-
Reprogramming of human somatic cells by embryonic stem cell cytoplast
-
Strelchenko N, Kukharenko V, Shkumatov A, Verlinsky O, Kuliev A, Verlinsky Y (2006) Reprogramming of human somatic cells by embryonic stem cell cytoplast. Reprod. BioMed. Online 12, 107-111.
-
(2006)
Reprod. BioMed. Online
, vol.12
, pp. 107-111
-
-
Strelchenko, N.1
Kukharenko, V.2
Shkumatov, A.3
Verlinsky, O.4
Kuliev, A.5
Verlinsky, Y.6
-
85
-
-
79953895218
-
Rebooted cells tackle ethical concerns. Fusion technique resets adult skin to embryonic state
-
published online 27 June 2005.
-
Check E (2005b) Rebooted cells tackle ethical concerns. Fusion technique resets adult skin to embryonic state. Nat. News, published online 27 June 2005; doi.
-
(2005)
Nat. News
-
-
Check, E.1
-
86
-
-
0041733400
-
Induction of stem cell-like plasticity in mononuclear cells derived from immobilized adult human peripheral blood
-
Abuljadayel IS (2003) Induction of stem cell-like plasticity in mononuclear cells derived from immobilized adult human peripheral blood. Curr. Med. Res. Opin. 19, 355-375.
-
(2003)
Curr. Med. Res. Opin.
, vol.19
, pp. 355-375
-
-
Abuljadayel, I.S.1
-
87
-
-
19344366847
-
Unraveling the molecular basis for regenerative cellular plasticity
-
Odelberg SJ (2004) Unraveling the molecular basis for regenerative cellular plasticity. PLoS Biol. 2, E232.
-
(2004)
PLoS Biol.
, vol.2
-
-
Odelberg, S.J.1
-
88
-
-
0035923683
-
Mammalian myotube dedifferentiation induced by newt regeneration extract
-
McGann CJ, Odelberg SJ, Keating MT (2001) Mammalian myotube dedifferentiation induced by newt regeneration extract. Proc. Natl. Acad. Sci. USA 98, 13699-13704.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13699-13704
-
-
McGann, C.J.1
Odelberg, S.J.2
Keating, M.T.3
-
89
-
-
0034703978
-
Dedifferentiation of mammalian myotubes induced by msx1
-
Odelberg SJ, Kollhoff A, Keating MT (2000) Dedifferentiation of mammalian myotubes induced by msx1. Cell 103, 1099-1109.
-
(2000)
Cell
, vol.103
, pp. 1099-1109
-
-
Odelberg, S.J.1
Kollhoff, A.2
Keating, M.T.3
-
90
-
-
0347717672
-
Dedifferentiation of lineage-committed cells by a small molecule
-
Chen S, Zhang Q, Wu X, Schultz PG, Ding S (2004) Dedifferentiation of lineage-committed cells by a small molecule. J. Am. Chem. Soc. 126, 410-411.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 410-411
-
-
Chen, S.1
Zhang, Q.2
Wu, X.3
Schultz, P.G.4
Ding, S.5
-
92
-
-
0037065356
-
A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells
-
Wu X, Ding S, Ding Q, Gray NS, Schultz PG (2002) A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells. J. Am. Chem. Soc., 124, 14520-14521.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 14520-14521
-
-
Wu, X.1
Ding, S.2
Ding, Q.3
Gray, N.S.4
Schultz, P.G.5
-
93
-
-
21844432133
-
Dedifferentiation of adult human myoblasts induced by ciliary neurotrophic factor in vitro
-
Chen X, Mao Z, Liu S, Liu H, Wang X, Wu H et al. (2005b) Dedifferentiation of adult human myoblasts induced by ciliary neurotrophic factor in vitro. Mol. Biol. Cell 16, 3140-3151.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 3140-3151
-
-
Chen, X.1
Mao, Z.2
Liu, S.3
Liu, H.4
Wang, X.5
Wu, H.6
-
94
-
-
0036251680
-
Reprogramming fibroblasts to express T-cell functions using cell extracts
-
Håkelien AM, Landsverk HB, Robl JM, Skålhegg BS, Collas P (2002) Reprogramming fibroblasts to express T-cell functions using cell extracts. Nat. Biotechnol. 20, 460-466.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 460-466
-
-
Håkelien, A.M.1
Landsverk, H.B.2
Robl, J.M.3
Skålhegg, B.S.4
Collas, P.5
-
96
-
-
33745632618
-
Nuclear reprogramming and pluripotency
-
Hochedlinger K, Jaenisch R (2006) Nuclear reprogramming and pluripotency. Nature 441, 1061-1067.
-
(2006)
Nature
, vol.441
, pp. 1061-1067
-
-
Hochedlinger, K.1
Jaenisch, R.2
-
97
-
-
33746012379
-
Simple recipe gives adult cells embryonic powers
-
Check E (2006) Simple recipe gives adult cells embryonic powers. Nature 442, 11.
-
(2006)
Nature
, vol.442
, pp. 11
-
-
Check, E.1
-
98
-
-
33746197983
-
Stem cell research. Four genes confer embryonic potential
-
Vogel G (2006) Stem cell research. Four genes confer embryonic potential. Science 313, 27.
-
(2006)
Science
, vol.313
, pp. 27
-
-
Vogel, G.1
-
99
-
-
79953856637
-
Identification of factors that generate Es-like pluripotent cells from fibroblast culture. Plenary Session IV
-
4th Annual Meeting, 29 June-1 July, Toronto, Canada. Available at.
-
Yamanaka S (2006), Identification of factors that generate Es-like pluripotent cells from fibroblast culture. Plenary Session IV. International Society for Stem Cell Research, 4th Annual Meeting, 29 June-1 July, Toronto, Canada. Available at ?
-
(2006)
International Society for Stem Cell Research
-
-
Yamanaka, S.1
-
100
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblasts cultures by defined factors
-
Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblasts cultures by defined factors. Cell 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
101
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
-
102
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita K, Ichisaka T, Yamanaka S (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317.
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
103
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K et al. (2007) Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1, 55-70.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
Utikal, J.4
Eminli, S.5
Arnold, K.6
-
104
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K et al. (2007) In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448, 318-324.
-
(2007)
Nature
, vol.448
, pp. 318-324
-
-
Wernig, M.1
Meissner, A.2
Foreman, R.3
Brambrink, T.4
Ku, M.5
Hochedlinger, K.6
-
105
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
-
106
-
-
57849146150
-
Breakthrough of the year. Reprogramming cells
-
Vogel G (2008) Breakthrough of the year. Reprogramming cells. Science 322, 1766-1767.
-
(2008)
Science
, vol.322
, pp. 1766-1767
-
-
Vogel, G.1
-
107
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA et al. (2008) Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451, 141-146.
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
Yabuuchi, A.4
Huo, H.5
Ince, T.A.6
-
108
-
-
41349090105
-
Generation of human induced pluripotent stem cells from dermal fibroblasts
-
Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R et al. (2008) Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc. Natl. Acad. Sci. USA 105, 2883-2888.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2883-2888
-
-
Lowry, W.E.1
Richter, L.2
Yachechko, R.3
Pyle, A.D.4
Tchieu, J.5
Sridharan, R.6
-
109
-
-
58949094552
-
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells
-
Marion RM, Strati K, Li H, Tejera A, Schoeftner S, Ortega S et al. (2009) Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell 4, 141-154.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 141-154
-
-
Marion, R.M.1
Strati, K.2
Li, H.3
Tejera, A.4
Schoeftner, S.5
Ortega, S.6
-
110
-
-
0036017195
-
Pluripotemt stem cells - model of embryonic development, tool for gene targeting and basis of cell therapy
-
Prelle K, Zink N, Wolf E (2002) Pluripotemt stem cells - model of embryonic development, tool for gene targeting and basis of cell therapy. Anat. Histol. Embryol. 31, 169-186.
-
(2002)
Anat. Histol. Embryol.
, vol.31
, pp. 169-186
-
-
Prelle, K.1
Zink, N.2
Wolf, E.3
-
111
-
-
69949089630
-
iPS cells produce viable mice through tetraploid complementation
-
Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T et al. (2009) iPS cells produce viable mice through tetraploid complementation. Nature 461, 86-90.
-
(2009)
Nature
, vol.461
, pp. 86-90
-
-
Zhao, X.Y.1
Li, W.2
Lv, Z.3
Liu, L.4
Tong, M.5
Hai, T.6
-
112
-
-
35148845584
-
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
-
Meissner A, Wernig M, Jaenisch R (2007) Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat. Biotechnol. 25, 1177-1181.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1177-1181
-
-
Meissner, A.1
Wernig, M.2
Jaenisch, R.3
-
113
-
-
62949220231
-
Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
-
Feng B, Ng JH, Heng JC, Ng HH (2009) Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 4, 301-312.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 301-312
-
-
Feng, B.1
Ng, J.H.2
Heng, J.C.3
Ng, H.H.4
-
114
-
-
48749109906
-
Improved efficacy and pace of generating induced pluripotent cells from human and fetal fibroblasts
-
Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G et al. (2008) Improved efficacy and pace of generating induced pluripotent cells from human and fetal fibroblasts. Stem Cells 26, 1998-2005.
-
(2008)
Stem Cells
, vol.26
, pp. 1998-2005
-
-
Mali, P.1
Ye, Z.2
Hommond, H.H.3
Yu, X.4
Lin, J.5
Chen, G.6
-
115
-
-
46449094276
-
Dissecting direct reprogramming through integrative genome analysis
-
Mikkelsen TS, Hanna J, Zhang K, Ku M, Wernig M, Schorderet P et al. (2008) Dissecting direct reprogramming through integrative genome analysis. Nature 454, 49-55.
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, K.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
-
116
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Zhao Y, Yin X, Qin H, Zhu F, Liu H, Ysang W et al. (2008) Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cells 3, 475-479.
-
(2008)
Cell Stem Cells
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
Zhu, F.4
Liu, H.5
Ysang, W.6
-
117
-
-
66149160608
-
Embryonic stem-cell-specific microRNAs promote induced pluripotency
-
Judson RL, Babiarz JE, Venere M, Blelloch R (2009) Embryonic stem-cell-specific microRNAs promote induced pluripotency. Nat. Biotechnol. 27, 459-461.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 459-461
-
-
Judson, R.L.1
Babiarz, J.E.2
Venere, M.3
Blelloch, R.4
-
118
-
-
34548445454
-
Generation of induced pluripotent stem cells in the absence of drug selection
-
Blelloch R, Venere M, Yen J, Ramalho-Santos M (2007) Generation of induced pluripotent stem cells in the absence of drug selection. Cell Stem Cell 1, 245-247.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 245-247
-
-
Blelloch, R.1
Venere, M.2
Yen, J.3
Ramalho-Santos, M.4
-
119
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T et al. (2008) Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26, 101-106.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
Takahashi, K.4
Ichisaka, T.5
Aoi, T.6
-
120
-
-
37549008674
-
c-Myc is dispensable for direct reprogramming of mouse fibroblasts
-
Wernig M, Meissner A, Cassidy JP, Jaenisch R (2008) c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2, 10-12.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 10-12
-
-
Wernig, M.1
Meissner, A.2
Cassidy, J.P.3
Jaenisch, R.4
-
121
-
-
0033533669
-
Virus treatment questioned after gene therapy death
-
Lehrman S (1999) Virus treatment questioned after gene therapy death. Nature 401, 517-518.
-
(1999)
Nature
, vol.401
, pp. 517-518
-
-
Lehrman, S.1
-
122
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, von Kalle C, Schmidt M, Le Deist F, Wulfraat N, McIntyre E et al. (2003) A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348, 255-258.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 255-258
-
-
Hacein-Bey-Abina, S.1
von Kalle, C.2
Schmidt, M.3
Le Deist, F.4
Wulfraat, N.5
McIntyre, E.6
-
123
-
-
55849115999
-
Induced pluripotent stem cells generated without viral integration
-
Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K (2008) Induced pluripotent stem cells generated without viral integration. Science 322, 945-949.
-
(2008)
Science
, vol.322
, pp. 945-949
-
-
Stadtfeld, M.1
Nagaya, M.2
Utikal, J.3
Weir, G.4
Hochedlinger, K.5
-
124
-
-
58549096370
-
Reprogramming of murine and human somatic cells using a single polycistronic vector
-
Carey BW, Markoulaki S, Hanna J, Saha K, Gao Q, Mitalipova M et al. (2009) Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc. Natl. Acad. Sci. USA 106, 157-162.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 157-162
-
-
Carey, B.W.1
Markoulaki, S.2
Hanna, J.3
Saha, K.4
Gao, Q.5
Mitalipova, M.6
-
125
-
-
65249149666
-
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
-
Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G (2009) Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells 27, 543-549.
-
(2009)
Stem Cells
, vol.27
, pp. 543-549
-
-
Sommer, C.A.1
Stadtfeld, M.2
Murphy, G.J.3
Hochedlinger, K.4
Kotton, D.N.5
Mostoslavsky, G.6
-
126
-
-
67049155513
-
Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector
-
Gonzalez F, Barragan Monasterio M, Tiscornia G, Montserrat Pulido N, Vassena R, Batlle Morera LB et al. (2009) Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector. Proc. Natl. Acad. Sci. USA 106, 8918-8922.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8918-8922
-
-
Gonzalez, F.1
Barragan Monasterio, M.2
Tiscornia, G.3
Montserrat Pulido, N.4
Vassena, R.5
Batlle Morera, L.B.6
-
127
-
-
55849117368
-
Generation of mouse induced pluripotent stem cells without viral vectors
-
Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S (2008) Generation of mouse induced pluripotent stem cells without viral vectors. Science 322, 949-953.
-
(2008)
Science
, vol.322
, pp. 949-953
-
-
Okita, K.1
Nakagawa, M.2
Hyenjong, H.3
Ichisaka, T.4
Yamanaka, S.5
-
128
-
-
64749083939
-
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R et al. (2009) piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770.
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
Desai, R.4
Mileikovsky, M.5
Hämäläinen, R.6
-
129
-
-
64749111225
-
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
-
Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K (2009) Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458, 771-775.
-
(2009)
Nature
, vol.458
, pp. 771-775
-
-
Kaji, K.1
Norrby, K.2
Paca, A.3
Mileikovsky, M.4
Mohseni, P.5
Woltjen, K.6
-
130
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, Slukvin II et al. (2009) Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797-801.
-
(2009)
Science
, vol.324
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
Tian, S.4
Stewart, R.5
Slukvin, I.I.6
-
131
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecules compounds
-
Huangfu D, Maehr R, Guo W, Eijkelenboom A, Sniyow M, Chen AE et al. (2008) Induction of pluripotent stem cells by defined factors is greatly improved by small-molecules compounds. Nat. Biotechnol. 26, 795-797.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
Eijkelenboom, A.4
Sniyow, M.5
Chen, A.E.6
-
132
-
-
58049192815
-
Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors
-
Li W, Wei W, Zhu S, Zhu J, Shi Y, Lin T et al. (2009) Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell 4, 16-19.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 16-19
-
-
Li, W.1
Wei, W.2
Zhu, S.3
Zhu, J.4
Shi, Y.5
Lin, T.6
-
133
-
-
67049158201
-
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of KLf4
-
Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S et al. (2009) Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of KLf4. Proc. Natl. Acad. Sci. USA 106, 8912-8917.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8912-8917
-
-
Lyssiotis, C.A.1
Foreman, R.K.2
Staerk, J.3
Garcia, M.4
Mathur, D.5
Markoulaki, S.6
-
134
-
-
44349103591
-
A combined chemical and genetic approach for the generation of induced pluripotent stem cells
-
Shi Y, Do JT, Desponts C, Hahm HS, Schöler HR, Ding S (2008) A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2, 525-528.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 525-528
-
-
Shi, Y.1
Do, J.T.2
Desponts, C.3
Hahm, H.S.4
Schöler, H.R.5
Ding, S.6
-
135
-
-
66049143859
-
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
-
Kim D, Kim CH, Moon JI, Chung YG, Chang MY, Han BS et al. (2009) Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472-476.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 472-476
-
-
Kim, D.1
Kim, C.H.2
Moon, J.I.3
Chung, Y.G.4
Chang, M.Y.5
Han, B.S.6
-
136
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T et al. (2009) Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4, 381-384.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
Zhu, S.4
Han, D.W.5
Lin, T.6
-
137
-
-
63049090064
-
A fresh Look at iPS Cells
-
Yamanaka S (2009) A fresh Look at iPS Cells. Cell 137, 13-17.
-
(2009)
Cell
, vol.137
, pp. 13-17
-
-
Yamanaka, S.1
-
138
-
-
77749292119
-
Stem cells. Reprogrammed cells come up short, for now
-
Vogel G (2010) Stem cells. Reprogrammed cells come up short, for now. Science 327, 1191.
-
(2010)
Science
, vol.327
, pp. 1191
-
-
Vogel, G.1
-
139
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu BY, Weick JP, Yu J, Ma LXC, Zhang XQ, Thomson JA et al. (2010) Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc. Natl. Acad. Sci. USA 107, 4335-4340.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 4335-4340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
Ma, L.X.C.4
Zhang, X.Q.5
Thomson, J.A.6
-
140
-
-
77950995392
-
Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence
-
Feng Q, Lu SJ, Klimanskaya I, Gomes I, Kim D, Chung Y et al. (2010) Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence. Stem Cells 28, 704-712.
-
(2010)
Stem Cells
, vol.28
, pp. 704-712
-
-
Feng, Q.1
Lu, S.J.2
Klimanskaya, I.3
Gomes, I.4
Kim, D.5
Chung, Y.6
-
141
-
-
77953212683
-
Straight talk with George Daley
-
Dolgin E (2010) Straight talk with George Daley. Nat. Med. 16, 624.
-
(2010)
Nat. Med.
, vol.16
, pp. 624
-
-
Dolgin, E.1
-
142
-
-
79953872426
-
New ethical questions are being raised in stem cell research
-
Available at (accessed 12 December 2009).
-
Leibel C (2009) New ethical questions are being raised in stem cell research. Medical News Today, Available at (accessed 12 December 2009).
-
(2009)
Medical News Today
-
-
Leibel, C.1
-
143
-
-
79953902812
-
No embryos were harmed
-
15 December.
-
Linda Geddes, No embryos were harmed. New Scientist. 15 December 2007, pp.44-45
-
(2007)
New Scientist
, pp. 44-45
-
-
Linda, G.1
-
144
-
-
18344408969
-
Derivation of oocytes from mouse embryonic stem cells
-
Hübner K, Fuhrmann G, Christenson LK, Kehler J, Reinbold R, De la Fuente R et al. (2003) Derivation of oocytes from mouse embryonic stem cells. Science 300, 1251-1256.
-
(2003)
Science
, vol.300
, pp. 1251-1256
-
-
Hübner, K.1
Fuhrmann, G.2
Christenson, L.K.3
Kehler, J.4
Reinbold, R.5
De la Fuente, R.6
-
145
-
-
0141816785
-
Embryonic stem cells can form germ cells in vitro
-
Toyooka Y, Tsunekawa N, Akasu R, Noce T (2003) Embryonic stem cells can form germ cells in vitro. Proc. Natl. Acad. Sci. USA 100, 11457-11462.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11457-11462
-
-
Toyooka, Y.1
Tsunekawa, N.2
Akasu, R.3
Noce, T.4
-
146
-
-
33745499559
-
In vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring mice
-
Nayernia K, Nolte J, Michelmann HW, Lee JH, Rathsack K, Drusenheimer N (2006) In vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring mice. Dev. Cell 11, 125-132.
-
(2006)
Dev. Cell
, vol.11
, pp. 125-132
-
-
Nayernia, K.1
Nolte, J.2
Michelmann, H.W.3
Lee, J.H.4
Rathsack, K.5
Drusenheimer, N.6
-
147
-
-
70449651657
-
Human DAZL DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation
-
Kee K, Angeles VT, Flores M, Nguyen HN, Reijo Pera RA (2009) Human DAZL DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. Nature 462, 222-225.
-
(2009)
Nature
, vol.462
, pp. 222-225
-
-
Kee, K.1
Angeles, V.T.2
Flores, M.3
Nguyen, H.N.4
Reijo Pera, R.A.5
-
148
-
-
67649183597
-
Pluripotential stem cell-derived gametes: truth and (potential) consequences
-
Mathews DJ, Donovan PJ, Harris J, Lovell-Badge R, Savulescu J, Faden R (2009) Pluripotential stem cell-derived gametes: truth and (potential) consequences. Cell Stem Cell 5, 11-14.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 11-14
-
-
Mathews, D.J.1
Donovan, P.J.2
Harris, J.3
Lovell-Badge, R.4
Savulescu, J.5
Faden, R.6
-
149
-
-
74949087802
-
The bioethics of stem cell research and therapy
-
Hyun I (2010) The bioethics of stem cell research and therapy. J. Clin. Invest. 120, 71-75.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 71-75
-
-
Hyun, I.1
-
150
-
-
77953159822
-
Human iPS cell-based therapy: considerations before clinical applications
-
Sun N, Longaker MT, Wu JC (2010) Human iPS cell-based therapy: considerations before clinical applications. Cell Cycle 9, 880-885.
-
(2010)
Cell Cycle
, vol.9
, pp. 880-885
-
-
Sun, N.1
Longaker, M.T.2
Wu, J.C.3
-
151
-
-
74049154451
-
Stem cell research policy and iPS cells
-
Caulfield T, Scott C, Hyun I, Lovell-Badge R, Kato K, Zarzeczny A (2010) Stem cell research policy and iPS cells. Nat. Methods 7, 28-33.
-
(2010)
Nat. Methods
, vol.7
, pp. 28-33
-
-
Caulfield, T.1
Scott, C.2
Hyun, I.3
Lovell-Badge, R.4
Kato, K.5
Zarzeczny, A.6
-
152
-
-
77952127464
-
Regulators must step up stem cell oversight
-
Editorial.
-
Editorial (2010) Regulators must step up stem cell oversight. Nat. Med. 16, 492.
-
(2010)
Nat. Med.
, vol.16
, pp. 492
-
-
-
153
-
-
71149109708
-
iPS cells: mapping the policy issues
-
Zarzeczny A, Scott C, Hyun I, Bennett J, Chandler J, Chgarge S et al. (2009) iPS cells: mapping the policy issues. Cell 139, 1032-1037.
-
(2009)
Cell
, vol.139
, pp. 1032-1037
-
-
Zarzeczny, A.1
Scott, C.2
Hyun, I.3
Bennett, J.4
Chandler, J.5
Chgarge, S.6
|