Development of human cloned blastocysts following somatic cell nuclear transfer with adult fibroblasts

Stem Cells

Volumn 26, Issue 2, 2008, Pages 485-493

  French, Andrew J ^a   Adams, Catharine A ^b   Anderson, Linda S ^b   Kitchen, John R ^c   Hughes, Marcus R ^c   Wood, Samuel H ^a,b  

^a Stemagen Corporation   (United States)

^b Reproductive Sciences Center   (United States)

^c Genesis Genetics Institute LLC ^*  (United States)

Author keywords

Blastocysts; Egg donation; Embryo; Human; Nuclear transfer; Oocytes; Somatic cell nuclear transfer

Indexed keywords

CYTOCHALASIN B; DNA; MITOCHONDRIAL DNA;

ADULT; ARTICLE; BLASTOCYST; CELL CLONING; CELL CYCLE; CELL DEGENERATION; CELL DIFFERENTIATION; CELL DIVISION; CELL MATURATION; CELL NUCLEUS TRANSPLANTATION; CELL THERAPY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOLYSIS; DNA FINGERPRINTING; EMBRYO; ENUCLEATION; FERTILIZATION IN VITRO; FIBROBLAST; GENITAL SYSTEM; HUMAN; HUMAN CELL; INFORMED CONSENT; KARYOTYPE; MALE; MEDICAL RESEARCH; OOCYTE; OOCYTE DEVELOPMENT; PARTHENOGENESIS; PREGNANCY; SOMATIC CELL;

ADULT; BLASTOCYST; CELL LINE; CLONING, ORGANISM; DNA, MITOCHONDRIAL; EMBRYO CULTURE TECHNIQUES; EMBRYONIC DEVELOPMENT; FEMALE; FIBROBLASTS; HUMANS; MALE; MICROSATELLITE REPEATS; NUCLEAR TRANSFER TECHNIQUES; OOCYTES; PARTHENOGENESIS;

EID: 39449113141     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0252     Document Type: Article

References (59)

1. Lerou PH, Daley GQ. Therapeutic potential of embryonic stem cells. Blood Rev 2005;19:321-331.
2. Doss MX, Koehler CI, Gissel C et al. Embryonic stem cells: A promising tool for cell replacement therapy. J Cell Mol Med 2004;8:465-473.
3. Vats A, Tolley NS, Bishop AE et al. Embryonic stem cells and tissue engineering: Delivering stem cells to the clinic. J R Soc Med 2005;98: 346-350.
4. Trounson A, Pera M. Potential benefits of cell cloning for human medicine. Reprod Fertil Dev 1998;10:121-125.
5. Hall VJ, Stojkovic P, Stojkovic M. Using therapeutic cloning to fight human disease: A conundrum or reality? STEM CELLS 2006;24:1628-1637.
6. Colman A, Kind A. Therapeutic cloning: Concepts and practicalities. Trends Biotechnol 2000;18:192-196.
7. Mollard R, Denham M, Trounson A. Technical advances and pitfalls on the way to human cloning. Differentiation 2002;70:1-9.
8. Trounson AO. Future and applications of cloning. Methods Mol Biol 2006;348:319-332.
9. Hochedlinger K, Jaenisch R. Nuclear transplantation, embryonic stem cells, and the potential for cell therapy. N Engl J Med 2003;349:275-286.
10. French AJ, Wood SH, Trounson AO. Human therapeutic cloning (NTSC): Applying research from mammalian reproductive cloning. Stem Cell Rev 2006;2:265-276.
11. Cho MK, McGee G, Magnus D. Research conduct. Lessons of the stem cell scandal. Science 2006;311:614-615.
12. Lewis IM, Munsie MJ, French AJ et al. The cloning cycle: From amphibia to mammals and back. Reprod Med Rev 2001;9:3-33.
13. Campbell KH. Nuclear equivalence, nuclear transfer, and the cell cycle. Cloning 1999;1:3-15.
14. Vajta G, Gjerris M. Science and technology of farm animal cloning: State of the art. Anim Reprod Sci 2006;92:211-230.
15. Stojkovic M, Stojkovic P, Leary C et al. Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes. Reprod Biomed Online 2005;11:226-231.
16. Lu C, Lin G, Xie C et al. Reconstruction of human embryos derived from somatic cells. Chinese Sci Bull 2003;48:1840-1843.
17. Cibelli JB, Kiessling AA, Cuniff K et al. Somatic cell nuclear transfer in humans: Pronuclear and early embryonic development. J Regen Med 2001;2:25-31.
18. Heindryckx B, De Sutter P, Gerris J et al. Embryo development after successful somatic cell nuclear transfer to in vitro matured human germinal vesicle oocytes. Hum Reprod 2007;22:1982-1990.
19. Lavoir MC, Weier J, Conaghan J et al. Poor development of human nuclear transfer embryos using failed fertilized oocytes. Reprod Biomed Online 2005;11:740-744.
20. Hall VJ, Compton D, Stojkovic P et al. Developmental competence of human in vitro aged oocytes as host cells for nuclear transfer. Hum Reprod 2007;22:52-62.
21. Collas P, Robl JM. Relationship between nuclear remodeling and development in nuclear transplant rabbit embryos. Biol Reprod 1991; 45:455-465.
22. Cheong HT, Takahashi Y, Kanagawa H. Relationship between nuclear remodeling and subsequent development of mouse embryonic nuclei transferred to enucleated oocytes. Mol Reprod Dev 1994;37:138-145.
23. Stice SL, Keefer CL, Matthews L. Bovine nuclear transfer embryos: Oocyte activation prior to blastomere fusion. Mol Reprod Dev 1994;38: 61-68.
24. Simerly C, Navara C, Hyun SH et al. Embryogenesis and blastocyst development after somatic cell nuclear transfer in nonhuman primates: Overcoming defects caused by meiotic spindle extraction. Dev Biol 2004;276:237-252.
25. Committee on Guidelines for Human Embryonic Stem Cell Research BoLS, Division on Earth and Life studies, Board on Health Sciences Policy, Institute of Medicine. Guidelines for Human Embryonic Stem Cell Research. Washington, DC: National Academies Press, 2005.
26. Daley GQ, Richter LA, Auerbach JM et al. Ethics: The ISSCR guidelines for human embryonic stem cell research. Science 2007;315:603-604.
27. Choudhary M, Haimes E, Herbert M et al. Demographic, medical and treatment characteristics associated with couples' decisions to donate fresh spare embryos for research. Hum Reprod 2004;19:2091-2096.
28. Bjuresten K, Hovatta O. Donation of embryos for stem cell research - How many couples consent? Hum Reprod 2003;18:1353-1355.
29. Muasher SJ, Abdallah RT, Hubayter ZR. Optimal stimulation protocols for in vitro fertilization. Fertil Steril 2006;86:267-273.
30. Boquest AC, Day BN, Prather RS. Flow cytometric cell cycle analysis of cultured porcine fetal fibroblast cells. Biol Reprod 1999;60:1013-1019.
31. Bielorai B, Hughes MR, Auerbach AD et al. Successful umbilical cord blood transplantation for Fanconi anemia using preimplantation genetic diagnosis for HLA-matched donor. Am J Hematol 2004;77:397-399.
32. Chong MD, Calloway CD, Klein SB et al. Optimization of a duplex amplification and sequencing strategy for the HVI/HVII regions of human mitochondrial DNA for forensic casework. Forensic Sci Int 2005;154:137-148.
33. Gabriel MN, Calloway CD, Reynolds RL et al. Identification of human remains by immobilized sequence-specific oligonucleotide probe analysis of mtDNA hypervariable regions I and II. Croat Med J 2003;44:293-298.
34. Surani A. False impressions on human cloning. Reprod Biomed Online 2003;6:398-399.
35. Kim K, Ng K, Rugg-Gunn P et al. Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell 2007 [Epub ahead of print].
36. Jones GM, Trounson AO, Gardner DK et al. Evolution of a culture protocol for successful blastocyst development and pregnancy. Hum Reprod 1998;13:169-177.
37. Desai N, Kinzer D, Loeb A et al. Use of synthetic serum substitute and alpha-minimum essential medium for the extended culture of human embryos to the blastocyst stage. Hum Reprod 1997;12:328-335.
38. Edwards RG, Beard HK. Is the success of human IVF more a matter of genetics and evolution than growing blastocysts? Hum Reprod 1999;14: 1-4.
39. Archer J, Gook DA, Edgar DH. Blastocyst formation and cell numbers in human frozen-thawed embryos following extended culture. Hum Reprod 2003;18:1669-1673.
40. Revazova ES, Turovets NA, Kochetkova OD et al. Patient-specific stem cell lines derived from human parthenogenetic blastocysts. Cloning Stem Cells 2007;9:432-449.
41. Renwick P, Ogilvie CM. Preimplantation genetic diagnosis for monogenic diseases: Overview and emerging issues. Expert Rev Mol Diagn 2007;7:33-43.
42. Katz MG, Trounson AO, Cram DS. DNA fingerprinting of sister blastomeres from human IVF embryos. Hum Reprod 2002;17:752-759.
43. Zakhartchenko V, Stojkovic M, Brem G et al. Karyoplast-cytoplast volume ratio in bovine nuclear transfer embryos: Effect on developmental potential. Mol Reprod Dev 1997;48:332-338.
44. Peura TT, Lewis IM, Trounson AO. The effect of recipient oocyte volume on nuclear transfer in cattle. Mol Reprod Dev 1998;50:185-191.
45. Wakayama T, Yanagimachi R. The first polar body can be used for the production of normal offspring in mice. Biol Reprod 1998;59:100-104.
46. Balakier H, Casper RF. Experimentally induced parthenogenetic activation of human oocytes. Hum Reprod 1993;8:740-743.
47. Rinaudo P, Pepperell JR, Buradgunta S et al. Dissociation between intracellular calcium elevation and development of human oocytes treated with calcium ionophore. Fertil Steril 1997;68:1086-1092.
48. Nakagawa K, Yamano S, Nakasaka H et al. A combination of calcium ionophore and puromycin effectively produces human parthenogenones with one haploid pronucleus. Zygote 2001;9:83-88.
49. Machaty Z, Prather RS. Strategies for activating nuclear transfer oocytes. Reprod Fertil Dev 1998;10:599-613.
50. Homa ST, Swann K. A cytosolic sperm factor triggers calcium oscillations and membrane hyperpolarizations in human oocytes. Hum Reprod 1994;9:2356-2361.
51. Saunders CM, Larman MG, Parrington J et al. PLC zeta: A spermspecific trigger of Ca(2+) oscillations in eggs and embryo development. Development 2002;129:3533-3544.
52. Swann K, Saunders CM, Rogers NT et al. PLCzeta(zeta): A sperm protein that triggers Ca2+ oscillations and egg activation in mammals. Semin Cell Dev Biol 2006;17:264-273.
53. Rogers NT, Hobson E, Pickering S et al. Phospholipase Czeta causes Ca2+ oscillations and parthenogenetic activation of human oocytes. Reproduction 2004;128:697-702.
54. Boiani M, Eckardt S, Scholer HR et al. Oct4 distribution and level in mouse clones: Consequences for pluripotency. Genes Dev 2002;16:1209-1219.
55. Kishigami S, Hikichi T, Van Thuan N et al. Normal specification of the extraembryonic lineage after somatic nuclear transfer. FEBS Lett 2006;580:1801-1806.
56. Wakayama S, Hikichi T, Suetsugu R et al. Efficient establishment of mouse embryonic stem cell lines from single blastomeres and polar bodies. STEM CELLS 2007;25:986-993.
57. Klimanskaya I, Chung Y, Becker S et al. Human embryonic stem cell lines derived from single blastomeres. Nature 2006;444:481-485.
58. Zhang X, Stojkovic P, Przyborski S et al. Derivation of human embryonic stem cells from developing and arrested embryos. STEM CELLS 2006;24:2669-2676.
59. Byrne JA, Pedersen DA, Clepper LL et al. Producing primate embryonic stem cells by somatic cell nuclear transfer. Nature 2007;450:497-502.