Late activation of stress-activated protein kinases/c-Jun N-terminal kinases triggered by cisplatin-induced DNA damage in repair-defective cells

Journal of Biological Chemistry

Volumn 286, Issue 15, 2011, Pages 12991-13001

  Helbig, Lars ^a   Damrot, Julia ^a   Hülsenbeck, Johannes ^a   Köberle, Beate ^a   Brozovic, Anamaria ^b   Osmak, Maja ^b   Fiket, Zeljka ^b   Kaina, Bernd ^a   Fritz, Gerhard ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIA-TELANGIECTASIA MUTATED; CIS-PLATIN; DNA ADDUCTS; DNA DAMAGES; DNA DOUBLE STRAND BREAKS; DNA LESIONS; DNA REPAIR PROTEINS; GENOTOXINS; JUN N-TERMINAL KINASE; MOUSE CELLS; NUCLEOTIDE EXCISION REPAIR; PLASMID DNA; REPLICATION PROTEIN A; RHO GTPASES; STRESS-ACTIVATED PROTEINS; TYROSINE KINASE;

AMINO ACIDS; DNA; DRUG THERAPY; ENZYMES; GENES; IONIZING RADIATION; PHOSPHORYLATION; PLATINUM COMPOUNDS; REPAIR; SIGNALING; TRANSCRIPTION;

NUCLEIC ACIDS;

ATR PROTEIN; CISPLATIN; HISTONE H2AX; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STRESS ACTIVATED PROTEIN KINASE; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; COCKAYNE SYNDROME; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EXCISION REPAIR; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE PROTEINS; CELLS, CULTURED; CISPLATIN; DNA ADDUCTS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; MICE; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 79953836781     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.190645     Document Type: Article

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