A facile three-component [3+2]-cycloaddition/annulation domino protocol for the regio- and diastereoselective synthesis of novel penta- and hexacyclic cage systems, involving the generation of two heterocyclic rings and five contiguous stereocenters

Tetrahedron

Volumn 67, Issue 17, 2011, Pages 3132-3139

  Suresh Kumar, Raju ^a   Osman, Hasnah ^a   Perumal, Subbu ^b   Menéndez, J Carlos ^c   Ashraf Ali, Mohamed ^d   Ismail, Rusli ^d   Soo Choon, Tan ^d  

^a SCHOOL OF PHYSICS   (Malaysia)

^b MADURAI KAMARAJ UNIVERSITY   (India)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

Author keywords

Cage compounds; Dipolar cycloadditions; Domino reactions; Multicomponent reactions; Spiro compounds

Indexed keywords

CARBON; FUSED HETEROCYCLIC RINGS; IMINE; NITROGEN; SPIRO COMPOUND;

ANNULATION REACTION; ARTICLE; CHEMICAL REACTION; CYCLOADDITION; DIPOLE; MICROWAVE IRRADIATION; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 79953701317     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2011.02.058     Document Type: Article

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