Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: Bleomycin, tallysomycin, and zorbamycin

Journal of Natural Products

Volumn 74, Issue 3, 2011, Pages 526-536

  Galm, Ute ^a   Wendt Pienkowski, Evelyn ^a   Wang, Liyan ^a   Huang, Sheng Xiong ^a   Unsin, Claudia ^a   Tao, Meifeng ^a   Coughlin, Jane M ^a   Shen, Ben ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYKETIDE SYNTHASE; SUGAR; SYNTHETASE; TALLYSOMYCIN; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; ZORBAMYCIN;

ACTINOMYCETALES; AMINO TERMINAL SEQUENCE; ANTIBIOTIC BIOSYNTHESIS; BACTERIAL GENE; CARBOHYDRATE METABOLISM; CARBOXY TERMINAL SEQUENCE; DRUG STRUCTURE; GENE CLUSTER; GENE LOCUS; GLYCOSYLATION; MOLECULAR CLONING; PROTEIN DOMAIN; REVIEW; STREPTOALLOTEICHUS HINDUSTANUS; STREPTOMYCES; STREPTOMYCES FLAVOVIRIDIS; STREPTOMYCES VERTICILLUS;

ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL PRODUCTS; BLEOMYCIN; GLYCOPEPTIDES; MULTIGENE FAMILY; PEPTIDE SYNTHASES;

STREPTOALLOTEICHUS HINDUSTANUS; STREPTOMYCES FLAVOVIRIDIS; STREPTOMYCES VERTICILLUS;

EID: 79953240352     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np1008152     Document Type: Review

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