Biocatalytic conversion of avermectin to 4″-oxo-avermectin: Characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes

Applied and Environmental Microbiology

Volumn 71, Issue 11, 2005, Pages 6968-6976

  Jungmann, Volker ^a   Molnár, István ^b,c   Hammer, Philip E ^b,e   Hill, D Steven ^b,f   Zirkle, Ross ^b,g   Buckel, Thomas G ^b,h   Buckel, Dagmar ^a   Ligon, James M ^b,f   Pachlatko, J Paul ^a,d  

^a SYNGENTA CROP PROTECTION AG   (Switzerland)

^b SYNGENTA BIOTECHNOLOGY INC   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d Athenix Corp ^*  (Switzerland)

^e Athenix Corp   (United States)

^f BASF Agricultural Product Group   (United States)

^g Martek Biosciences   (United States)

^h F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; ENZYMES; ESCHERICHIA COLI; GENES; PROTEINS;

AVERMECTIN; BIOCATALYTIC CONVERSION; OXIDATION REACTION;

BIOCATALYSTS;

4'' OXOAVERMECTIN; AVERMECTIN; AVERMECTIN DERIVATIVE; CYTOCHROME P450; EMAMECTIN BENZOATE; GENE PRODUCT; HISTIDINE; INSECTICIDE; NATURAL PRODUCT; PROTEIN EMA1; PROTEIN EMA16; PROTEIN EMA17; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ENZYME;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BIOCATALYST; BIOTRANSFORMATION; EMA1 GENE; EMA16 GENE; EMA17 GENE; ENZYME KINETICS; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE OVEREXPRESSION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PROTEIN FAMILY; STEREOCHEMISTRY; STREPTOMYCES;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; IVERMECTIN; KINETICS; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; STEREOISOMERISM; STREPTOMYCES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; STREPTOMYCES;

EID: 32044440744     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.71.11.6968-6976.2005     Document Type: Article

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