ATR (ataxia telangiectasia mutated- and Rad3-related kinase) is activated by mild hypothermia in mammalian cells and subsequently activates p53

Biochemical Journal

Volumn 435, Issue 2, 2011, Pages 499-508

  Roobol, Anne ^a   Roobol, Jo ^a   Carden, Martin J ^a   Bastide, Amandine ^b   Willis, Anne E ^b   Dunn, Warwick B ^c   Goodacre, Royston ^c   Smales, C Mark ^a  

^a UNIVERSITY OF KENT   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Ataxia telangiectasia mutated and rad3 related kinase (ATR); Chinese hamster ovary cell (CHO cell); Cold shock; Hypothermia; Lipidomics; Metabolomics; p53

Indexed keywords

ATR PROTEIN; MEMBRANE LIPID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; COLD; CONTROLLED STUDY; HYPOTHERMIA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; LIPID ANALYSIS; MAMMAL CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE PROTEINS; CELLS; CHO CELLS; COLD TEMPERATURE; CRICETINAE; CRICETULUS; ENZYME ACTIVATION; HELA CELLS; HUMANS; HYPOTHERMIA; MAMMALS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SEVERITY OF ILLNESS INDEX; TUMOR SUPPRESSOR PROTEIN P53;

ATAXIA TELANGIECTASIA; CRICETULUS GRISEUS; MAMMALIA;

EID: 79953204942     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101303     Document Type: Article

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