Osmotic Shock Induces G1 Arrest through p53 Phosphorylation at Ser33 by Activated p38MAPK without Phosphorylation at Ser15 and Ser20

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 39115-39122

  Kishi, Hiroto ^a,b   Nakagawa, Kazumi ^a   Matsumoto, Mitsuhiro ^b   Suga, Moritaka ^b   Ando, Masayuki ^b   Taya, Yoichi ^c   Yamaizumi, Masaru ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEGRADATION; ENZYME INHIBITION;

OSMOTIC SHOCKS;

BIOCHEMISTRY;

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN KINASE; PROTEIN MDM2; PROTEIN P21; PROTEIN P300; PROTEIN P53; SERINE; CDKN1A PROTEIN, HUMAN; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; E1A ASSOCIATED P300 PROTEIN; ENZYME INHIBITOR; EP300 PROTEIN, MOUSE; IMIDAZOLE DERIVATIVE; LUCIFERASE; MAP2K6 PROTEIN, HUMAN; MAP2K6 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEAR PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN); PYRIDINE DERIVATIVE; TRANSACTIVATOR PROTEIN;

ACETYLATION; ARTICLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; ANIMAL; CELL CYCLE; CELL LINE; CELL NUCLEUS; CHEMISTRY; DOMINANT GENE; DOWN REGULATION; FIBROBLAST; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; METABOLISM; MOUSE; MOUSE MUTANT; OSMOTIC PRESSURE; PHOSPHORYLATION; PLASMID; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERODIAGNOSIS; TIME; TRANSACTIVATION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

ACETYLATION; ANIMALS; BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL CYCLE; CELL LINE; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DOWN-REGULATION; E1A-ASSOCIATED P300 PROTEIN; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROBLASTS; G1 PHASE; GENES, DOMINANT; GENES, P53; HUMANS; IMIDAZOLES; LUCIFERASES; LYSINE; MAP KINASE KINASE 6; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; NUCLEAR PROTEINS; OSMOTIC PRESSURE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; PYRIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERINE; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035914446     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105134200     Document Type: Article

References (57)

1. Albertyn, J., Hohmann, S., Thevelein, J. M., and Prior, B. A. (1994) Mol. Cell. Biol. 14, 4135-4144
2. Brewster, J. L., de Valoir, T., Dwyer, N. D., Winter, E., and Gustin, M. C. (1993) Science 259, 1760-1763
3. Han, J., Lee, J. D., Bibbs, L., and Ulevitch, R. J. (1994) Science 265, 808-811
4. Bohlen, H. G., and Unthank, J. L. (1989) Am. J. Physiol. 257, G438-G446
5. Naftalin, R. J., and Pedley, K. C. (1990) FEBS Lett. 260, 187-194
6. Gottschalk, C. W., and Mylle, M. (1959) Am. J. Physiol. 196, 927-936
7. Maltzman, W., and Czyzyk, L. (1984) Mol. Cell. Biol. 4, 1689-1694
8. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B., and Craig, R. W. (1991) Cancer Res. 51, 6304-6311
9. Graeber, T. G., Peterson, J. F., Tsai, M., Monica, K., Fornace, A. J., Jr., and Giaccia, A. J. (1994) Mol. Cell. Biol. 14, 6264-6277
10. Nitta, M., Okamura, H., Aizawa, S., and Yamaizumi, M. (1997) Oncogene 15, 561-568
11. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. (1993) Cell 75, 805-816
12. Kastan, M. B., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., and Fornace, A. J., Jr. (1992) Cell 71, 587-597
13. Hwang, B. J., Ford, J. M., Hanawalt, P. C., and Chu, G. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 424-428
14. Tanaka, H., Arakawa, H., Yamaguchi, T., Shiraishi, K., Fukuda, S., Matsui, K., Takei, Y., and Nakamura, Y. (2000) Nature 404, 42-49
15. Miyashita, T., and Reed, J. C. (1995) Cell 80, 293-299
16. Oda, K., Arakawa, H., Tanaka, T., Matsuda, K., Tanikawa, C, Mori, T., Nishimori, H., Tamai, K., Tokino, T., Nakamura, Y., and Taya, Y. (2000) Cell 102, 849-862
17. Haupt, Y., Maya, R., Kazaz, A., and Oren, M. (1997) Nature 387, 296-299
18. Kubbutat, M. H., Jones, S. N., and Vousden, K. H. (1997) Nature 387, 299-303
19. Kussie, P. H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A. J., and Pavletich, N. P. (1996) Science 274, 948-953
20. Cliby, W. A., Roberts, C. J., Cimprich, K. A., Stringer, C. M., Lamb, J. R., Schreiber, S. L., and Friend, S. H. (1998) EMBO J. 17, 159-169
21. Chehab, N. H., Malikzay, A., Appel, M., and Halazonetis, T. D. (2000) Genes Dev. 14, 278-288
22. Shieh, S. Y., Ahn, J., Tamai, K., Taya, Y., and Prives, C. (2000) Genes Dev. 14, 289-300
23. Chehab, N. H., Malikzay, A., Stavridi, E. S., and Halazonetis, T. D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 13777-13782
24. Unger, T., Juven-Gershon, T., Moallem, E., Berger, M., Sionov, R. V., Lozano, G., Oren, M., and Haupt, Y. (1999) EMBO J. 18, 1805-1814
25. Alarcon, R., Koumenis, C., Geyer, R. K., Maki, C. G., and Giaccia, A. J. (1999) Cancer Res. 59, 6046-6051
26. Koumenis, C., Alarcon, R., Hammond, E., Sutphin, P., Hoffman, W., Murphy, M., Derr, J., Taya, Y., Lowe, S. W., Kastan, M., and Giaccia, A., (2001) Mol. Cell. Biol. 21, 1297-1310
27. Banin, S., Moyal, L., Shieh, S., Taya, Y., Anderson, C. W., Chessa, L., Smorodinsky, N. I., Prives, C., Reiss, Y., Shiloh, Y., and Ziv, Y. (1998) Science 281, 1674-1677
28. Canman, C. E., Lim, D. S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., and Siliciano, J. D, (1998) Science 281, 1677-1679
29. Nakagawa, K., Taya, Y., Tamai, K., and Yamaizumi, M. (1999) Mol. Cell. Biol. 19, 2828-2834
30. Tibbetts, R. S., Brumbaugh, K. M., Williams, J. M., Sarkaria, J. N., Cliby, W. A., Shieh, S. Y., Taya, Y., Prives, C., and Abraham, R. T. (1999) Genes Dev. 13, 152-157
31. Bulavin, D. V., Saito, S., Hollander, M. C., Sakaguchi, K., Anderson, C. W., Appella, E., and Fornace, A. J., Jr. (1999) EMBO J. 18, 6845-6854
32. Sanchez-Prieto, R., Rojaz, J. M., Taya, Y., and Gutkind, J. S. (2000) Cancer Res. 60, 2464-2472
33. Liu, L., Scolnick, D. M., Trievel, R. C., Zhang, H. B., Marmorstein, R., Halazonetis, T. D., and Berger, S. L. (1999) Mol. Cell. Biol. 19, 1202-1209
34. Sakaguchi, K., Herrera, J. E., Saito, S., Miki, T., Bustin, M., Vassilev, A., Anderson, C. W., and Appella, E. (1998) Genes Dev. 12, 2831-2841
35. Lambert, P. F., Kashanchi, F., Radonovich, M. F., Shiekhattar, R., and Brady, J. N. (1998) J. Biol. Chem. 273, 33048-33053
36. Dumaz, N., and Meek, D. W. (1999) EMBO J. 18, 7002-7010
37. Ito, A., Lai, C. H., Zhao, X., Saito, S., Hamilton, M. H., Appella, E., and Yao, T. P. (2001) EMBO J. 20, 1331-1340
38. Sugano, T., Nitta, M., Ohmori, H., and Yamaizumi, M. (1995) Jpn. J. Cancer Res. 86, 415-418
39. Dmitrieva, N., Kultz, D., Michea, L., Ferraris, J., and Burg, M. (2000) J. Biol. Chem. 275, 18243-18247
40. Itoh, T., Fujiwara, Y., Ono, T., and Yamaizumi, M. (1995) Am. J. Hum. Genet. 56, 1267-1276
41. Tsukada, T., Tomooka, Y., Takai, S., Ueda, Y., Nishikawa, S., Yagi, T., Tokunaga, T., Takeda, N., Suda, Y., Abe, S., Matsuo, I., Ikawa, Y., and Aizawa, S. (1993) Oncogene 8, 3313-3322
42. Shieh, S. Y., Ikeda, M., Taya, Y., and Prives, C. (1997) Cell 91, 325-334
43. Ko, L. J., Shieh, S. Y., Chen, X., Jayaraman, L., Tamai, K., Taya, Y., Prives, C., and Pan, Z. Q. (1997) Mol. Cell. Biol. 17, 7220-7229
44. Shieh, S. Y., Taya, Y., and Prives, C. (1999) EMBO J. 18, 1815-1823
45. Yamaizumi, M., Sugano, T., Asahina, H., Okada, Y., and Uchida, T. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 1476-1479
46. El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) Cell 75, 817-825
47. Dulic, V., Kaufmann, W. K., Wilson, S. J., Tlsty, T. D., Lees, E., Harper, J. W., Elledge, S. J., and Reed, S. L. (1994) Cell 76, 1013-1023
48. Bacus, S. S., Yarden, Y., Oren, M., Chin, D. M., Lyass, L., Zelnick, C. R., Kazarov, A., Toyofuku, W., Gray-Bablin, J., Beerli, R. R., Hynes, N. E., Nikiforov, M., Haffner, R., Gudkov, A., and Keyomarsi, K. (1996) Oncogene 12, 2535-2547
49. Fenteany, G., Standaert, R. F., Lane, W. S., Choi, S., Corey, E. J., and Schreiber, S. L. (1995) Science 268, 726-731
50. Ichijo, H. (1999) Oncogene 18, 6087-6093
51. Goedert, M., Cuenda, A., Craxton, M., Jakes, R., and Cohen, P. (1997) EMBO J. 16, 3563-3571
52. Kapoor, M., and Lozano, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2834-2837
53. Lu, H., Taya, Y., Ikeda, M., and Levine, A. J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6399-6402
54. Huang, C., Ma, W. Y., Maxiner, A., Sun, Y., and Dong, Z. (1999) J. Biol. Chem. 274, 12229-12235
55. Keller, D., Zeng, X., Li, X., Kapoor, M., Iordanov, M. S., Taya, Y., Lozano, G., Magun, B., and Lu, H. (1999) Biochem. Biophys. Res. Commun. 261, 464-471
56. Ashcroft, M., Taya, Y., and Vousden, K. H. (2000) Mol. Cell. Biol. 20, 3224-3233
57. Buschmann, T., Fuchs, S. Y., Lee, C. G., Pan, Z. Q., and Ronai, Z. (2000) Cell 101, 753-762