Hypothermia causes a reversible, p53-mediated cell cycle arrest in cultured fibroblasts

Oncology Research

Volumn 10, Issue 11-12, 1998, Pages 605-610

  Matijasevic, Zdenka ^a   Snyder, John E ^a   Ludlum, David B ^b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Cell cycle arrest; Fibroblasts; Hypothermia; P53 protein

Indexed keywords

PROTEIN P53;

ANIMAL; ARTICLE; CELL CULTURE; CELL CYCLE; CYTOLOGY; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HYPOTHERMIA; METABOLISM; METHODOLOGY; MOUSE; PHYSIOLOGY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL CYCLE; CELLS, CULTURED; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; HYPOTHERMIA; MICE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0032250227     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Streffer, C.; van Beuningen, D. The biological basis for tumour therapy by hyperthermia and radiation. Recent Results Cancer Res. 104:24-70; 1987.
2. Engelhardt, R. Hyperthermia and drugs. Recent Results Cancer Res. 104:136-203; 1987.
3. ++ protect against irreversible damage during CNS ischemia. Stroke 15:695-698; 1984.
4. Dietrich, W. D.; Busto, R.; Alonso, O.; Globus, M. Y.-T.; Ginsberg, M. D. Intra-ischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats. J. Cereb. Blood Flow Metab. 13:541-549; 1993.
5. Kumar, K.; Wu, X.; Evans, A. T. Expression of c-fos and fos-B proteins following transient forebrain ischemia: Effect of hypothermia. Mol. Brain Res. 42:337-343; 1996.
6. Kamme, F.; Wieloch, T. Induction of junD mRNA after transient forebrain ischemia in the rat. Effects of hypothermia. Mol. Brain Res. 43:51-56; 1996.
7. Li, G. C.; Mivechi, N. F.; Weitzel, G. Heat shock proteins, thermotolerance, and their relevance to clinical hyperthermia. Int. J. Hyperthermia 11:459-488; 1995.
8. Mosser, D. D.; Caron, A. W.; Bourget, L.; Denis-Larose, C.; Massie, B. Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis. Mol. Cell. Biol. 17:5317-5327; 1997.
9. Gabai, V. L.; Meriin, A. B.; Mosser, D. D.; Caron, A. W.; Rits, S.; Shifrin, V. I.; Sherman, M. Y. Hsp70 prevents activation of stress kinases. J. Biol. Chem. 272:18033-18037; 1997.
10. Jones, P. G.; VanBogelen, R. A.; Neidhardt, F. C. Induction of proteins in response to low temperature in Escherichia coll. J. Bacteriol. 169:2092-2095; 1987.
11. Jones, P. G.; Mitta, M.; Kim, Y.; Jiang, W.; Inouye, M. Cold shock induces a major ribosomal-associated protein that unwinds double-stranded RNA in Escherichia coli. Proc. Natl. Acad. Sci. USA 93:76-80; 1996.
12. Jiang, W.; Hou, Y.; Inouye, M. CspA, the major cold-shock protein of Escherichia coli, is an RNA chaperone. J. Biol. Chem. 272:196-202; 1997.
13. Rao, P. N.; Engelberg, J. HeLa cells: Effects of temperature on the life cycle. Science 148:1092-1094; 1965.
14. Nishiyama, H.; Itoh, K.; Kaneko, Y.; Kishishita, M.; Yoshida, O.; Fujita, J. A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth. J. Cell Biol. 137:899-908; 1997.
15. Jones, S. N.; Sands, A. T.; Hancock, A. R.; Vogel, H.; Donehower, L. A.; Linke, S. P.; Wahl, G. M.; Bradley, A. The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2. Proc. Natl. Acad. Sci. USA 93:14106-14111; 1996.
16. Donehower, L. A.; Harvery, M.; Slagle, B. L.; McArthur, M. J.; Montgomery, C. A., Jr.; Butel, J. S.; Bradley, A. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215-221; 1992.
17. Hotz, M. A.; Gong, J.; Traganos, F.; Darzynkiewicz, Z. Flow cytometric detection of apoptosis: Comparison of the assays of in situ DNA degradation and chromatin changes. Cytometry 15:237-244; 1994.
18. El-Deiry, W. S.; Tokino, T.; Velculescu, V. E.; Levy, D. B.; Par-sons, R.; Trent, J. M.; Lin, D.; Mcrcer, W. E. Kinzler, K. W.; Vogelstein, B. WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825; 1993.
19. Dulic, V.; Kaufmann, W. K.; Wilson, S. J.; Tlsty, T. D.; Lees, E.; Harper, J. W.; Elledge, S. J.; Reed, S. I. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76:1013-1024; 1994.
20. Waldman, T.; Kinzler, K. W.; Vogelstein, B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55:5187-5190; 1995.
21. Matsumoto, H.; Shimura, M.; Omatsu, T.; Okaichi, K.; Majima, H.; Ohnishi, T. p53 proteins accumulated by heat stress associate with heat shock proteins HSP72/HSC73 in human glioblastoma cell lines. Cancer Lett. 87:39-46; 1994.
22. Ohnishi, T.; Wang, X.; Ohnishi, K.; Matsumoto, H.; Takahashi, A. p53-dependent induction of WAF1 by heat treatment in human glioblastoma cells. J. Biol. Chem. 271:14510-14513; 1996.
23. Nitta, M.; Okamura, H.; Aizawa, S.; Yamaizumi, M. Heat shock induces transient p53-depcndent cell cycle arrest at G1/S. Oncogene 15:561-568; 1997.
24. Ohnishi, T.; Wang, X.; Ohnishi, K.; Takahashi, A. p53-dependent induction of WAF1 by cold shock in human glioblastoma cells. Oncogcnc 16:1507-1511; 1998.
25. 1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol. Cell. Biol. 14:6264-6277; 1994.
26. Cross, S. M.; Sanchez, C. A.; Morgan, C. A.; Schimke, M. K.; Ramel, S.; Idzerda, R. L.; Raskind, W. H.; Reid, B. J. A p53-dependent mouse spindle checkpoint. Science 267:1353-1356; 1995.
27. Harvey, M.; Sands, A. T.; Weiss, R. S.; Hegi, M. E.; Wiseman, R. W.; Pantazis, P.; Giovanella, B. C.; Tainsky, M. A.; Bradley, A.; Donehower, L. A. In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice. Oncogene 8:2457-2467; 1993.