Yeast go the whole HOG for the hyperosmotic response

Trends in Genetics

Volumn 18, Issue 8, 2002, Pages 405-412

  O'Rourke, Sean M ^b   Herskowitz, Ira ^b   O'Shea, Erin K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

ARTICLE; BIOSENSOR; CONTROLLED STUDY; GENE EXPRESSION; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STRESS; YEAST;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0036683337     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(02)02723-3     Document Type: Review

References (71)

1. Ecological significance of compatible solute accumulation by micro-organisms: From single cells to global climate
2. Physiology of osmotolerance in fungi
3. An osmosensing signal transduction pathway in yeast
4. Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
5. Pheromone response, mating and cell biology
6. Osmotic adaptation in yeast - Control of the yeast osmolyte system
7. Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation
8. Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
9. The evolution of the MAP kinase pathways: Coduplication of interacting proteins leads to new signaling cascades
10. P38 MAPK signalling cascades: Ancient roles and new functions
11. P38 MAP kinases: Beyond the stress response
12. The p38 signal transduction pathway: Activation and function
13. Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe
14. Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin β homologs NMD5 and XPO1
15. Stress-induced map kinase Hog1 is part of transcription activation complexes
16. The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene
17. Heat stress activates the yeast high-osmolarity glycerol mitogen-activated protein kinase pathway, and protein tyrosine phosphatases are essential under heat stress
18. Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway
19. The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae
20. Response of Saccharomyces cerevisiae to severe osmotic stress: Evidence for a novel activation mechanism of the HOG MAP kinase pathway
21. A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch
22. Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor
23. Histidine kinases and response regulator proteins in two-component signaling systems
24. Two-component signal transduction
25. Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 'two-component' osmosensor
26. Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator
27. Differential stabilities of phosphorylated response regulator domains reflect functional roles of the yeast osmoregulatory SLN1 and SSK1 proteins
28. Novel role for an HPt domain in stabilizing the phosphorylated state of a response regulator domain
29. The extracellular domain of the Saccharomyces cerevisiae Sln1p membrane osmolarity sensor is necessary for kinase activity
30. Intracellular glycerol levels modulate the activity of Sln1p, a Saccharomyces cerevisiae two-component regulator
31. The eukaryotic two-component histidine kinase Sln1p regulates OCH1 via the transcription factor, Skn7p
32. Candidate osmosensors from Candida utilis and Kluyveromyces lactis: Structural and functional homology to the Sho1p putative osmosensor from Saccharomyces cerevisiae
33. Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway
34. Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: Scaffold role of Pbs2p MAPKK
35. Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo
36. Mutations in the SAM domain of STE50 differentially influence the MAPK-mediated pathways for mating, filamentous growth and osmotolerance in Saccharomyces cerevisiae
37. Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases
38. Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae
39. The transcriptional response of yeast to saline stress
40. The transcriptional response of Saccharomyces cerevisiae to osmotic shock. Hot1p and Msn2p/Msn4p are required for the induction of subsets of high osmolarity glycerol pathway-dependent genes
41. Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress
42. The Sko1p repressor and Gcn4p activator antagonistically modulate stress-regulated transcription in Saccharomyces cerevisiae
43. Multiple levels of control regulate the yeast cAMP-response element-binding protein repressor Sko1p in response to stress
44. Repressors and upstream repressing sequences of the stress-regulated ENA1 gene in Saccharomyces cerevisiae: BZIP protein Sko1p confers HOG-dependent osmotic regulation
45. The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage
46. Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p
47. Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity
48. Rck2, a member of the calmodulin-protein kinase family, links protein synthesis to high osmolarity MAP kinase signaling in budding yeast
49. Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase Hog1
50. Transient inhibition of translation initiation by osmotic stress
51. Regulation of cell cycle progression by Swe1p and Hog1p following hypertonic stress
52. Polarized localization of yeast Pbs2 depends on osmostress, the membrane protein Sho1 and Cdc42
53. Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity
54. Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast
55. Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase
56. Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast
57. Increased dosage of the MSN1 gene restores invertase expression in yeast mutants defective in the SNF1 protein kinase
58. A two-component system that regulates an osmosensing MAP kinase cascade in yeast
59. Two protein-tyrosine phosphatases inactivate the osmotic stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1
60. Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1
61. MAP kinase pathways in the yeast Saccharomyces cerevisiae
62. Activation of the Saccharomyces cerevisiae filamentation/invasion pathway by osmotic stress in high-osmolarity glycogen pathway mutants
63. The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: Isolation of a FUS3 mutant that is insensitive to the repression mechanism
64. MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
65. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles
66. Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins
67. MAP kinase cascades: Scaffolding signal specificity
68. MAP kinase dynamics in response to pheromones in budding yeast
69. Defects in protein glycosylation cause SHO1-dependent activation of a STE12 signaling pathway in yeast
70. The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components