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Volumn 11, Issue 4, 2011, Pages 278-288

Testicular germ cell tumours: Predisposition genes and the male germ cell niche

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; BLEOMYCIN; CHEMOKINE RECEPTOR CXCR4; CHORIONIC GONADOTROPIN; CISPLATIN; CYCLIN D2; ETOPOSIDE; FIBROBLAST GROWTH FACTOR RECEPTOR 3; IMATINIB; K RAS PROTEIN; LACTATE DEHYDROGENASE; PHOSPHATIDYLINOSITOL 3 KINASE; STEM CELL FACTOR; STROMAL CELL DERIVED FACTOR 1; SUNITINIB; TELOMERASE; TUMOR MARKER; VASCULOTROPIN;

EID: 79953034087     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc3021     Document Type: Review
Times cited : (78)

References (197)
  • 1
    • 14644396631 scopus 로고    scopus 로고
    • Testicular germ-cell tumours in a broader perspective
    • DOI 10.1038/nrc1568
    • Oosterhuis, J. W. & Looijenga, L. H. Testicular germ-cell tumours in a broader perspective. Nature Rev. Cancer 5, 210-222 (2005). (Pubitemid 40314952)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 210-222
    • Oosterhuis, J.W.1    Looijenga, L.H.J.2
  • 2
    • 33644648880 scopus 로고    scopus 로고
    • Testicular germ-cell cancer
    • DOI 10.1016/S0140-6736(06)68305-0, PII S0140673606683050
    • Horwich, A., Shipley, J. & Huddart, R. Testicular germ-cell cancer. Lancet 367, 754-765 (2006). (Pubitemid 43326294)
    • (2006) Lancet , vol.367 , Issue.9512 , pp. 754-765
    • Horwich, A.1    Shipley, J.2    Huddart, R.3
  • 3
    • 0020480783 scopus 로고
    • Specific chromosome change, i(12p), in testicular tumours?
    • Atkin, N. B. & Baker, M. C. Specific chromosome change, i(12p), in testicular tumours? Lancet 2, 1349 (1982).
    • (1982) Lancet , vol.2 , pp. 1349
    • Atkin, N.B.1    Baker, M.C.2
  • 4
    • 0020521395 scopus 로고
    • I(12p): Specific chromosomal marker in seminoma and malignant teratoma of the testis?
    • DOI 10.1016/0165-4608(83)90125-5
    • Atkin, N. B. & Baker, M. C. i(12p): specific chromosomal marker in seminoma and malignant teratoma of the testis? Cancer Genet. Cytogenet. 10, 199-204 (1983). (Pubitemid 13013934)
    • (1983) Cancer Genetics and Cytogenetics , vol.10 , Issue.2 , pp. 199-204
    • Atkin, N.B.1    Baker, M.C.2
  • 5
    • 0029931790 scopus 로고    scopus 로고
    • Reviews of chromosome studies in urological tumors. III. Cytogenetics and genes in testicular tumors
    • DOI 10.1016/S0022-5347(01)66124-X
    • Sandberg, A. A., Meloni, A. M. & Suijkerbuijk, R. F. Reviews of chromosome studies in urological tumors. III. Cytogenetics and genes in testicular tumors. J.-Urol. 155, 1531-1556 (1996). (Pubitemid 26126947)
    • (1996) Journal of Urology , vol.155 , Issue.5 , pp. 1531-1556
    • Sandberg, A.A.1    Meloni, A.M.2    Suijkerbuijk, R.F.3
  • 6
    • 0031877296 scopus 로고    scopus 로고
    • Triple-color FISH analysis of 12p amplification in testicular germ-cell tumors using 12p band-specific painting probes
    • DOI 10.1007/s001090050262
    • Henegariu, O., Vance, G. H., Heiber, D., Pera, M. & Heerema, N. A. Triple-color FISH analysis of 12p amplification in testicular germ-cell tumors using 12p band-specific painting probes. J.-Mol. Med. 76, 648-655 (1998). (Pubitemid 28361883)
    • (1998) Journal of Molecular Medicine , vol.76 , Issue.9 , pp. 648-655
    • Henegariu, O.1    Vance, G.H.2    Heiber, D.3    Pera, M.4    Heerema, N.A.5
  • 8
    • 0033819741 scopus 로고    scopus 로고
    • Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis
    • Roelofs, H. et-al. Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis. Am. J.-Pathol. 157, 1155-1166 (2000).
    • (2000) Am. J.-Pathol. , vol.157 , pp. 1155-1166
    • Roelofs, H.1
  • 9
    • 0031964896 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change
    • Summersgill, B. et-al. Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change. Br. J. Cancer 77, 305-313 (1998). (Pubitemid 28029548)
    • (1998) British Journal of Cancer , vol.77 , Issue.2 , pp. 305-313
    • Summersgill, B.1    Goker, H.2    Weber-Hall, S.3    Huddart, R.4    Horwich, A.5    Shipley, J.6
  • 12
    • 31544440121 scopus 로고    scopus 로고
    • Down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in-vivo differentiation of human male germ cell tumors
    • Korkola, J. E. et-al. Down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in-vivo differentiation of human male germ cell tumors. Cancer Res. 66, 820-827 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 820-827
    • Korkola, J.-E.1
  • 13
    • 26844475720 scopus 로고    scopus 로고
    • Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity
    • Giuliano, C. J. et-al. Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity. Biochim. Biophys. Acta 1731, 48-56 (2005).
    • (2005) Biochim. Biophys. Acta , vol.1731 , pp. 48-56
    • Giuliano, C.-J.1
  • 14
    • 0015499388 scopus 로고
    • Possible carcinoma-in-situ of the testis
    • Skakkebaek, N. E. Possible carcinoma-in-situ of the testis. Lancet 2, 516-517 (1972).
    • (1972) Lancet , vol.2 , pp. 516-517
    • Skakkebaek, N.E.1
  • 15
    • 0026920098 scopus 로고
    • A fetal testis with intratubular germ cell neoplasia (ITGCN)
    • Jacobsen, G. K. & Henriques, U. V. A fetal testis with intratubular germ cell neoplasia (ITGCN). Mod. Pathol. 5, 547-549 (1992).
    • (1992) Mod. Pathol. , vol.5 , pp. 547-549
    • Jacobsen, G.K.1    Henriques, U.V.2
  • 16
    • 0030071303 scopus 로고    scopus 로고
    • A fetus with Down syndrome and intratubular germ cell neoplasia
    • DOI 10.1080/107710496175921
    • Satge, D., Jacobsen, G. K., Cessot, F., Raffi, F. & Vekemans, M. A fetus with Down syndrome and intratubular germ cell neoplasia. Pediatr. Pathol. Lab. Med. 16, 107-112 (1996). (Pubitemid 26051406)
    • (1996) Pediatric Pathology and Laboratory Medicine , vol.16 , Issue.1 , pp. 107-112
    • Satge, D.1
  • 17
    • 0019501092 scopus 로고
    • Carcinoma in situ of testicular tissue adjacent to malignant germ-cell tumors: A study of 105 cases
    • DOI 10.1002/10 97-0142(1981 0601)47:11<266 0::AID-CNCR282 0471123>3.0.CO;2-6
    • Jacobsen, G. K., Henriksen, O. B. & von der Maase, H. Carcinoma in-situ of testicular tissue adjacent to malignant germ-cell tumors: a study of 105 cases. Cancer 47, 2660-2662 (1981). (Pubitemid 11113732)
    • (1981) Cancer , vol.47 , Issue.11 , pp. 2660-2662
    • Jacobsen, G.K.1    Henriksen, O.B.2    Von Der Maase, H.3
  • 18
    • 17144387569 scopus 로고    scopus 로고
    • Prevalence of testicular intraepithelial neoplasia in healthy males
    • DOI 10.1097/01.ju.0000154348.68575.95
    • Linke, J., Loy, V. & Dieckmann, K. P. Prevalence of testicular intraepithelial neoplasia in healthy males. J.-Urol. 173, 1577-1579 (2005). (Pubitemid 40524774)
    • (2005) Journal of Urology , vol.173 , Issue.5 , pp. 1577-1579
    • Linke, J.1    Loy, V.2    Dieckmann, K.-P.3
  • 19
    • 34547918833 scopus 로고    scopus 로고
    • Why human extragonadal germ cell tumours occur in the midline of the body: Old concepts, new perspectives
    • Oosterhuis, J. W., Stoop, H., Honecker, F. & Looijenga, L. H. Why human extragonadal germ cell tumours occur in the midline of the body: old concepts, new perspectives. Int. J.-Androl. 30, 256-264 (2007).
    • (2007) Int. J.-Androl. , vol.30 , pp. 256-264
    • Oosterhuis, J.W.1    Stoop, H.2    Honecker, F.3    Looijenga, L.-H.4
  • 20
    • 1842779079 scopus 로고    scopus 로고
    • Long-term sequelae after cancer therapy: Survivorship after treatment for testicular cancer
    • DOI 10.1080/02841860310023174
    • Fossa, S. D. Long-term sequelae after cancer therapy-survivorship after treatment for testicular cancer. Acta Oncol. 43, 134-141 (2004). (Pubitemid 38478899)
    • (2004) Acta Oncologica , vol.43 , Issue.2 , pp. 134-141
    • Fossa, S.D.1
  • 21
    • 0037504532 scopus 로고    scopus 로고
    • Cardiovascular disease as a long-term complication of treatment for testicular cancer
    • Huddart, R. A. et-al. Cardiovascular disease as a long-term complication of treatment for testicular cancer. J. Clin. Oncol. 21, 1513-1523 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1513-1523
    • Huddart, R.-A.1
  • 22
    • 17644431109 scopus 로고    scopus 로고
    • Cardiovascular morbidity in long-term survivors of metastatic testicular cancer
    • Meinardi, M. T. et-al. Cardiovascular morbidity in long-term survivors of metastatic testicular cancer. J. Clin. Oncol. 18, 1725-1732 (2000).
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1725-1732
    • Meinardi, M.-T.1
  • 23
    • 33644835617 scopus 로고    scopus 로고
    • Long-term risk of cardiovascular disease in 5-year survivors of testicular cancer
    • van den Belt-Dusebout, A. W. et-al. Long-term risk of cardiovascular disease in 5-year survivors of testicular cancer. J. Clin. Oncol. 24, 467-475 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , pp. 467-475
    • Van Den Belt-Dusebout, A.-W.1
  • 24
    • 25144512005 scopus 로고    scopus 로고
    • Second cancers among 40,576 testicular cancer patients: Focus on long-term survivors
    • Travis, L. B. et-al. Second cancers among 40,576 testicular cancer patients: focus on long-term survivors. J.-Natl Cancer Inst. 97, 1354-1365 (2005).
    • (2005) J.-Natl Cancer Inst. , vol.97 , pp. 1354-1365
    • Travis, L.-B.1
  • 25
    • 35348890176 scopus 로고    scopus 로고
    • Treatment-specific risks of second malignancies and cardiovascular disease in 5-year survivors of testicular cancer
    • van den Belt-Dusebout, A. W. et-al. Treatment-specific risks of second malignancies and cardiovascular disease in 5-year survivors of testicular cancer. J. Clin. Oncol. 25, 4370-4378 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4370-4378
    • Van Den Belt-Dusebout, A.-W.1
  • 26
    • 0028009086 scopus 로고
    • Testicular cancer in blacks. A multicenter experience
    • Moul, J. W. et-al. Testicular cancer in blacks. A multicenter experience. Cancer 73, 388-393 (1994).
    • (1994) Cancer , vol.73 , pp. 388-393
    • Moul, J.-W.1
  • 27
    • 0026585997 scopus 로고
    • Familial testicular cancer: A report of the UK family register, estimation of risk and an HLA class 1 sib-pair analysis
    • Forman, D. et-al. Familial testicular cancer: a report of the UK family register, estimation of risk and an HLA class 1 sib-pair analysis. Br. J. Cancer 65, 255-262 (1992).
    • (1992) Br. J. Cancer , vol.65 , pp. 255-262
    • Forman, D.1
  • 29
    • 0345256389 scopus 로고    scopus 로고
    • Familial risk of cancer: Data for clinical counseling and cancer genetics
    • DOI 10.1002/ijc.11478
    • Hemminki, K., Li, X. & Czene, K. Familial risk of cancer: data for clinical counseling and cancer genetics. Int. J. Cancer 108, 109-114 (2004). (Pubitemid 37444452)
    • (2004) International Journal of Cancer , vol.108 , Issue.1 , pp. 109-114
    • Hemminki, K.1    Li, X.2    Czene, K.3
  • 30
    • 0037052644 scopus 로고    scopus 로고
    • Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-Cancer Database
    • DOI 10.1002/ijc.10332
    • Czene, K., Lichtenstein, P. & Hemminki, K. Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family Cancer Database. Int. J. Cancer 99, 260-266 (2002). (Pubitemid 34309484)
    • (2002) International Journal of Cancer , vol.99 , Issue.2 , pp. 260-266
    • Czene, K.1    Lichtenstein, P.2    Hemminki, K.3
  • 31
    • 77951585057 scopus 로고    scopus 로고
    • Architecture of inherited susceptibility to common cancer
    • Fletcher, O. & Houlston, R. S. Architecture of inherited susceptibility to common cancer. Nature Rev. Cancer 10, 353-361 (2010).
    • (2010) Nature Rev. Cancer , vol.10 , pp. 353-361
    • Fletcher, O.1    Houlston, R.S.2
  • 32
    • 31544460668 scopus 로고    scopus 로고
    • Genome-wide linkage screen for testicular germ cell tumour susceptibility loci
    • Crockford, G. P. et-al. Genome-wide linkage screen for testicular germ cell tumour susceptibility loci. Hum. Mol. Genet. 15, 443-451 (2006).
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 443-451
    • Crockford, G.-P.1
  • 33
    • 38049068815 scopus 로고    scopus 로고
    • From gonocytes to testicular cancer: The role of impaired gonadal development
    • Rajpert-de Meyts, E. & Hoei-Hansen, C. E. From gonocytes to testicular cancer: the role of impaired gonadal development. Ann. N. Y.-Acad. Sci. 1120, 168-180 (2007).
    • (2007) Ann. N. Y.-Acad. Sci. , vol.1120 , pp. 168-180
    • Rajpert-De Meyts, E.1    Hoei-Hansen, C.-E.2
  • 34
    • 0042913352 scopus 로고    scopus 로고
    • Age at immigration and duration of stay in relation to risk for testicular cancer among Finnish immigrants in Sweden
    • Ekbom, A., Richiardi, L., Akre, O., Montgomery, S. M. & Sparen, P. Age at immigration and duration of stay in relation to risk for testicular cancer among Finnish immigrants in Sweden. J.-Natl Cancer Inst. 95, 1238-1240 (2003). (Pubitemid 37069554)
    • (2003) Journal of the National Cancer Institute , vol.95 , Issue.16 , pp. 1238-1240
    • Ekbom, A.1    Richiardi, L.2    Akre, O.3    Montgomery, S.M.4    Sparen, P.5
  • 36
    • 0035804636 scopus 로고    scopus 로고
    • Cancer risk in men exposed in-utero to diethylstilbestrol
    • Strohsnitter, W. C. et-al. Cancer risk in men exposed in-utero to diethylstilbestrol. J.-Natl Cancer Inst. 93, 545-551 (2001).
    • (2001) J.-Natl Cancer Inst. , vol.93 , pp. 545-551
    • Strohsnitter, W.-C.1
  • 38
    • 4344689831 scopus 로고    scopus 로고
    • Clinical epidemiology of testicular germ cell tumors
    • DOI 10.1007/s00345-004-0398-8
    • Dieckmann, K. P. & Pichlmeier, U. Clinical epidemiology of testicular germ cell tumors. World J.-Urol. 22, 2-14 (2004). (Pubitemid 41406567)
    • (2004) World Journal of Urology , vol.22 , Issue.1 , pp. 2-14
    • Dieckmann, K.-P.1    Pichlmeier, U.2
  • 39
    • 21244468377 scopus 로고    scopus 로고
    • Fertility patterns prior to testicular cancer diagnosis
    • DOI 10.1007/s10552-004-4024-2
    • Baker, J. A., Buck, G. M., Vena, J. E. & Moysich, K. B. Fertility patterns prior to testicular cancer diagnosis. Cancer Causes Control 16, 295-299 (2005). (Pubitemid 40897848)
    • (2005) Cancer Causes and Control , vol.16 , Issue.3 , pp. 295-299
    • Baker, J.A.1    Buck, G.M.2    Vena, J.E.3    Moysich, K.B.4
  • 40
    • 23444438375 scopus 로고    scopus 로고
    • Subfertility and the risk of testicular germ cell tumors (United States)
    • DOI 10.1007/s10552-005-0169-x
    • Doria-Rose, V. P., Biggs, M. L. & Weiss, N. S. Subfertility and the risk of testicular germ cell tumors (United States). Cancer Causes Control 16, 651-656 (2005). (Pubitemid 41110955)
    • (2005) Cancer Causes and Control , vol.16 , Issue.6 , pp. 651-656
    • Doria-Rose, V.P.1    Biggs, M.L.2    Weiss, N.S.3
  • 41
    • 70349973694 scopus 로고    scopus 로고
    • Male infertility: A risk factor for testicular cancer
    • Hotaling, J. M. & Walsh, T. J. Male infertility: a risk factor for testicular cancer. Nature Rev. Urol. 6, 550-556 (2009).
    • (2009) Nature Rev. Urol. , vol.6 , pp. 550-556
    • Hotaling, J.M.1    Walsh, T.-J.2
  • 43
    • 0035004535 scopus 로고    scopus 로고
    • Testicular dysgenesis syndrome: An increasingly common developmental disorder with environmental aspects
    • Skakkebaek, N. E., Rajpert-De Meyts, E. & Main, K. M. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum. Reprod. 16, 972-978 (2001). (Pubitemid 32451837)
    • (2001) Human Reproduction , vol.16 , Issue.5 , pp. 972-978
    • Skakkebaek, N.E.1    Rajpert-De Meyts, E.2    Main, K.M.3
  • 44
    • 68949198159 scopus 로고    scopus 로고
    • Does a testicular dysgenesis syndrome exist?
    • Akre, O. & Richiardi, L. Does a testicular dysgenesis syndrome exist? Hum. Reprod. 24, 2053-2060 (2009).
    • (2009) Hum. Reprod. , vol.24 , pp. 2053-2060
    • Akre, O.1    Richiardi, L.2
  • 45
    • 76349116679 scopus 로고    scopus 로고
    • Familial coaggregation of cryptorchidism, hypospadias, and testicular germ cell cancer: A nationwide cohort study
    • Schnack, T. H., Poulsen, G., Myrup, C., Wohlfahrt, J. & Melbye, M. Familial coaggregation of cryptorchidism, hypospadias, and testicular germ cell cancer: a nationwide cohort study. J. Natl Cancer Inst. 102, 187-192 (2010).
    • (2010) J. Natl Cancer Inst. , vol.102 , pp. 187-192
    • Schnack, T.H.1    Poulsen, G.2    Myrup, C.3    Wohlfahrt, J.4    Melbye, M.5
  • 46
    • 65249120242 scopus 로고    scopus 로고
    • A signaling principle for the specification of the germ cell lineage in mice
    • Ohinata, Y. et-al. A signaling principle for the specification of the germ cell lineage in mice. Cell 137, 571-584 (2009).
    • (2009) Cell , vol.137 , pp. 571-584
    • Ohinata, Y.1
  • 47
    • 0037130207 scopus 로고    scopus 로고
    • A molecular programme for the specification of germ cell fate in mice
    • DOI 10.1038/nature00927
    • Saitou, M., Barton, S. C. & Surani, M. A. A molecular programme for the specification of germ cell fate in mice. Nature 418, 293-300 (2002). (Pubitemid 34790674)
    • (2002) Nature , vol.418 , Issue.6895 , pp. 293-300
    • Saitou, M.1    Barton, S.C.2    Surani, M.A.3
  • 49
    • 34249883075 scopus 로고    scopus 로고
    • Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells
    • DOI 10.1016/j.ydbio.2007.03.031, PII S0012160607002321
    • Farini, D., La Sala, G., Tedesco, M. & De Felici, M. Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells. Dev. Biol. 306, 572-583 (2007). (Pubitemid 46873531)
    • (2007) Developmental Biology , vol.306 , Issue.2 , pp. 572-583
    • Farini, D.1    La Sala, G.2    Tedesco, M.3    De Felici, M.4
  • 52
    • 0036679127 scopus 로고    scopus 로고
    • Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer
    • De Miguel, M. P., Cheng, L., Holland, E. C., Federspiel, M. J. & Donovan, P. J. Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer. Proc. Natl Acad. Sci. USA 99, 10458-10463 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 10458-10463
    • De Miguel, M.P.1    Cheng, L.2    Holland, E.C.3    Federspiel, M.J.4    Donovan, P.-J.5
  • 53
    • 33846146040 scopus 로고    scopus 로고
    • Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
    • DOI 10.1242/dev.02688
    • Runyan, C. et-al. Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development 133, 4861-4869 (2006). (Pubitemid 46085052)
    • (2006) Development , vol.133 , Issue.24 , pp. 4861-4869
    • Runyan, C.1    Schaible, K.2    Molyneaux, K.3    Wang, Z.4    Levin, L.5    Wylie, C.6
  • 55
    • 38849094674 scopus 로고    scopus 로고
    • Clearing the path for germ cells
    • DOI 10.1016/j.cell.2008.01.023, PII S0092867408001232
    • Knaut, H. & Schier, A. F. Clearing the path for germ cells. Cell 132, 337-339 (2008). (Pubitemid 351200514)
    • (2008) Cell , vol.132 , Issue.3 , pp. 337-339
    • Knaut, H.1    Schier, A.F.2
  • 58
    • 34248206088 scopus 로고    scopus 로고
    • What is left behind-quality control in germ cell migration
    • Boldajipour, B. & Raz, E. What is left behind-quality control in germ cell migration. Sci. STKE 2007, pe16 (2007).
    • (2007) Sci. STKE
    • Boldajipour, B.1    Raz, E.2
  • 59
    • 14844291401 scopus 로고    scopus 로고
    • Epigenetics and the germline
    • DOI 10.1530/rep.1.00360
    • Allegrucci, C., Thurston, A., Lucas, E. & Young, L. Epigenetics and the germline. Reproduction 129, 137-149 (2005). (Pubitemid 40340102)
    • (2005) Reproduction , vol.129 , Issue.2 , pp. 137-149
    • Allegrucci, C.1    Thurston, A.2    Lucas, E.3    Young, L.4
  • 60
  • 62
    • 70349309500 scopus 로고    scopus 로고
    • Foetal germ cells: Striking the balance between pluripotency and differentiation
    • Western, P. Foetal germ cells: striking the balance between pluripotency and differentiation. Int. J.-Dev. Biol. 53, 393-409 (2009).
    • (2009) Int. J.-Dev. Biol. , vol.53 , pp. 393-409
    • Western, P.1
  • 63
    • 20444370252 scopus 로고    scopus 로고
    • Nanog expression in mouse germ cell development
    • DOI 10.1016/j.modgep.2005.03.001, PII S1567133X05000219
    • Yamaguchi, S., Kimura, H., Tada, M., Nakatsuji, N. & Tada, T. Nanog expression in mouse germ cell development. Gene Expr. Patterns 5, 639-646 (2005). (Pubitemid 40796609)
    • (2005) Gene Expression Patterns , vol.5 , Issue.5 , pp. 639-646
    • Yamaguchi, S.1    Kimura, H.2    Tada, M.3    Nakatsuji, N.4    Tada, T.5
  • 65
    • 0142106351 scopus 로고    scopus 로고
    • Novel functions and signalling pathways for GDNF
    • DOI 10.1242/jcs.00786
    • Sariola, H. & Saarma, M. Novel functions and signalling pathways for GDNF. J. Cell Sci. 116, 3855-3862 (2003). (Pubitemid 37279301)
    • (2003) Journal of Cell Science , vol.116 , Issue.19 , pp. 3855-3862
    • Sariola, H.1    Saarma, M.2
  • 66
    • 0344306704 scopus 로고    scopus 로고
    • v WIW mutant mouse testis
    • DOI 10.1095/biolreprod.103.019323
    • Ohta, H., Tohda, A. & Nishimune, Y. Proliferation and differentiation of spermatogonial stem cells in the w/wv mutant mouse testis. Biol. Reprod. 69, 1815-1821 (2003). (Pubitemid 37505324)
    • (2003) Biology of Reproduction , vol.69 , Issue.6 , pp. 1815-1821
    • Ohta, H.1    Tohda, A.2    Nishimune, Y.3
  • 67
    • 35548997413 scopus 로고    scopus 로고
    • New insights into male gametogenesis: What about the spermatogonial stem cell niche?
    • Dadoune, J. P. New insights into male gametogenesis: what about the spermatogonial stem cell niche? Folia Histochem. Cytobiol. 45, 141-147 (2007).
    • (2007) Folia Histochem Cytobiol. , vol.45 , pp. 141-147
    • Dadoune, J.P.1
  • 69
    • 2642522727 scopus 로고    scopus 로고
    • Plzf is required in adult male germ cells for stem cell self-renewal
    • Buaas, F. W. et-al. Plzf is required in adult male germ cells for stem cell self-renewal. Nature Genet. 36, 647-652 (2004).
    • (2004) Nature Genet. , vol.36 , pp. 647-652
    • Buaas, F.-W.1
  • 70
    • 2642550555 scopus 로고    scopus 로고
    • Essential role of Plzf in maintenance of spermatogonial stem cells
    • Costoya, J. A. et-al. Essential role of Plzf in maintenance of spermatogonial stem cells. Nature Genet. 36, 653-659 (2004).
    • (2004) Nature Genet. , vol.36 , pp. 653-659
    • Costoya, J.-A.1
  • 72
    • 77955813904 scopus 로고    scopus 로고
    • Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation
    • Payne, C. J. et-al. Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells 28, 1424-1434 (2010).
    • (2010) Stem Cells , vol.28 , pp. 1424-1434
    • Payne, C.J.1
  • 75
    • 0037089555 scopus 로고    scopus 로고
    • New insights into testicular germ cell tumorigenesis from gene expression profiling
    • Skotheim, R. I. et-al. New insights into testicular germ cell tumorigenesis from gene expression profiling. Cancer Res. 62, 2359-2364 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 2359-2364
    • Skotheim, R.-I.1
  • 76
    • 0345687164 scopus 로고    scopus 로고
    • Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors
    • Sperger, J. M. et-al. Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. Proc. Natl Acad. Sci. USA 100, 13350-13355 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 13350-13355
    • Sperger, J.-M.1
  • 78
    • 0034922103 scopus 로고    scopus 로고
    • Chromosomal imbalances associated with carcinoma in-situ and associated testicular germ cell tumours of adolescents and adults
    • Summersgill, B., Osin, P., Lu, Y. J., Huddart, R. & Shipley, J. Chromosomal imbalances associated with carcinoma in-situ and associated testicular germ cell tumours of adolescents and adults. Br. J. Cancer 85, 213-220 (2001).
    • (2001) Br. J. Cancer , vol.85 , pp. 213-220
    • Summersgill, B.1    Osin, P.2    Lu, Y.J.3    Huddart, R.4    Shipley, J.5
  • 79
    • 0348103716 scopus 로고    scopus 로고
    • Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells
    • Draper, J. S. et-al. Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nature Biotech. 22, 53-54 (2004).
    • (2004) Nature Biotech. , vol.22 , pp. 53-54
    • Draper, J.-S.1
  • 80
    • 19944391945 scopus 로고    scopus 로고
    • Diagnostic value of OCT3/4 for pre-invasive and invasive testicular germ cell tumours
    • de Jong, J. et-al. Diagnostic value of OCT3/4 for pre-invasive and invasive testicular germ cell tumours. J. Pathol. 206, 242-249 (2005).
    • (2005) J. Pathol. , vol.206 , pp. 242-249
    • De Jong, J.1
  • 81
    • 0037458114 scopus 로고    scopus 로고
    • Dedifferentiation of primary spermatocytes into germ cell tumors in C. elegans Lacking the pumilio-like protein PUF-8
    • DOI 10.1016/S0960-9822(03)00005-8, PII S0960982203000058
    • Subramaniam, K. & Seydoux, G. Dedifferentiation of primary spermatocytes into germ cell tumors in, C. elegans lacking the pumilio-like protein PUF-8. Curr. Biol. 13, 134-139 (2003). (Pubitemid 36154341)
    • (2003) Current Biology , vol.13 , Issue.2 , pp. 134-139
    • Subramaniam, K.1    Seydoux, G.2
  • 82
    • 33646336640 scopus 로고    scopus 로고
    • Pluripotency of spermatogonial stem cells from adult mouse testis
    • Guan, K. et-al. Pluripotency of spermatogonial stem cells from adult mouse testis. Nature 440, 1199-1203 (2006).
    • (2006) Nature , vol.440 , pp. 1199-1203
    • Guan, K.1
  • 83
    • 28144443108 scopus 로고    scopus 로고
    • The y deletion gr/gr and susceptibility to testicular germ cell tumor
    • Nathanson, K. L. et-al. The Y deletion gr/gr and susceptibility to testicular germ cell tumor. Am. J.-Hum. Genet. 77, 1034-1043 (2005).
    • (2005) Am. J.-Hum. Genet. , vol.77 , pp. 1034-1043
    • Nathanson, K.-L.1
  • 84
    • 67649867946 scopus 로고    scopus 로고
    • Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer
    • Kanetsky, P. A. et-al. Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nature Genet. 41, 811-815 (2009).
    • (2009) Nature Genet. , vol.41 , pp. 811-815
    • Kanetsky, P.-A.1
  • 85
    • 67649876131 scopus 로고    scopus 로고
    • A genome-wide association study of testicular germ cell tumor
    • Rapley, E. A. et-al. A genome-wide association study of testicular germ cell tumor. Nature Genet. 41, 807-810 (2009).
    • (2009) Nature Genet. , vol.41 , pp. 807-810
    • Rapley, E.-A.1
  • 86
    • 77954144031 scopus 로고    scopus 로고
    • Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer
    • Turnbull, C. et-al. Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer. Nature Genet. 42, 604-607 (2009).
    • (2009) Nature Genet. , vol.42 , pp. 604-607
    • Turnbull, C.1
  • 87
    • 0028828142 scopus 로고
    • Differential expression of the c-kit proto-oncogene in germ cell tumours
    • Izquierdo, M. A. et-al. Differential expression of the c-kit proto-oncogene in germ cell tumours. J. Pathol. 177, 253-258 (1995).
    • (1995) J. Pathol. , vol.177 , pp. 253-258
    • Izquierdo, M.-A.1
  • 89
    • 10744221713 scopus 로고    scopus 로고
    • Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ Cell tumors
    • Looijenga, L. H. et-al. Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ Cell tumors. Cancer Res. 63, 7674-7678 (2003).
    • (2003) Cancer Res. , vol.63 , pp. 7674-7678
    • Looijenga, L.-H.1
  • 91
    • 3042696867 scopus 로고    scopus 로고
    • Somatic mutations of KIT in familial testicular germ cell tumours
    • Rapley, E. A. et-al. Somatic mutations of KIT in familial testicular germ cell tumours. Br. J. Cancer 90, 2397-2401 (2004).
    • (2004) Br. J. Cancer , vol.90 , pp. 2397-2401
    • Rapley, E.-A.1
  • 92
    • 20944449595 scopus 로고    scopus 로고
    • C-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens
    • DOI 10.1002/cncr.21064
    • Willmore-Payne, C., Layfield, L. J. & Holden, J. A. c-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens. Cancer 105, 165-170 (2005). (Pubitemid 40868896)
    • (2005) Cancer , vol.105 , Issue.3 , pp. 165-170
    • Willmore-Payne, C.1    Layfield, L.J.2    Holden, J.A.3
  • 93
    • 34547912136 scopus 로고    scopus 로고
    • KIT and RAS signalling pathways in testicular germ cell tumours: New data and a review of the literature
    • Goddard, N. C. et-al. KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literature. Int. J. Androl. 30, 337-349 (2007).
    • (2007) Int. J. Androl. , vol.30 , pp. 337-349
    • Goddard, N.-C.1
  • 94
    • 25844507795 scopus 로고    scopus 로고
    • Signaling by Kit protein-tyrosine kinase - The stem cell factor receptor
    • DOI 10.1016/j.bbrc.2005.08.055, PII S0006291X05017596
    • Roskoski, R. Jr. Signaling by Kit protein-tyrosine kinase-the stem cell factor receptor. Biochem. Biophys. Res. Commun. 337, 1-13 (2005). (Pubitemid 41393751)
    • (2005) Biochemical and Biophysical Research Communications , vol.337 , Issue.1 , pp. 1-13
    • Roskoski Jr., R.1
  • 95
    • 48549093520 scopus 로고    scopus 로고
    • Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice
    • Heaney, J. D., Lam, M. Y., Michelson, M. V. & Nadeau, J. H. Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice. Cancer Res. 68, 5193-5197 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 5193-5197
    • Heaney, J.D.1    Lam, M.Y.2    Michelson, M.V.3    Nadeau, J.H.4
  • 96
    • 85078510385 scopus 로고    scopus 로고
    • Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1
    • Sasaki, A. et-al. Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1. Cell Cycle 2, 281-282 (2003).
    • (2003) Cell Cycle , vol.2 , pp. 281-282
    • Sasaki, A.1
  • 97
    • 0347256705 scopus 로고    scopus 로고
    • Response markers and the molecular mechanisms of action of Gleevec in gastrointestinal stromal tumors
    • Frolov, A. et-al. Response markers and the molecular mechanisms of action of Gleevec in gastrointestinal stromal tumors. Mol. Cancer Ther. 2, 699-709 (2003).
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 699-709
    • Frolov, A.1
  • 98
    • 18844451747 scopus 로고    scopus 로고
    • Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase
    • DOI 10.1042/BJ20041181
    • Tsumura, Y., Toshima, J., Leeksma, O. C., Ohashi, K. & Mizuno, K. Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase. Biochem. J. 387, 627-637 (2005). (Pubitemid 40685696)
    • (2005) Biochemical Journal , vol.387 , Issue.3 , pp. 627-637
    • Tsumura, Y.1    Toshima, J.2    Leeksma, O.C.3    Ohashi, K.4    Mizuno, K.5
  • 99
    • 0034463078 scopus 로고    scopus 로고
    • Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis
    • DOI 10.1210/me.14.5.682
    • Yan, W., Samson, M., Jegou, B. & Toppari, J. Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis. Mol. Endocrinol. 14, 682-699 (2000). (Pubitemid 32260512)
    • (2000) Molecular Endocrinology , vol.14 , Issue.5 , pp. 682-699
    • Yan, W.1    Samson, M.2    Jegou, B.3    Toppari, J.4
  • 100
    • 33644877081 scopus 로고    scopus 로고
    • Activating mutations and/or expression levels of tyrosine kinase receptors GRB7, RAS, and BRAF in testicular germ cell tumors
    • DOI 10.1593/neo.05514
    • McIntyre, A. et-al. Activating mutations and/or expression levels of tyrosine kinase receptors GRB7, RAS, and BRAF in testicular germ cell tumors. Neoplasia 7, 1047-1052 (2005). (Pubitemid 44430982)
    • (2005) Neoplasia , vol.7 , Issue.12 , pp. 1047-1052
    • McIntyre, A.1    Summersgill, B.2    Spendlove, H.E.3    Huddart, R.4    Houlston, R.5    Shipley, J.6
  • 101
    • 0028895535 scopus 로고
    • N- and KRAS mutations in primary testicular germ cell tumors: Incidence and possible biological implications
    • Olie, R. A. et-al. N- and KRAS mutations in primary testicular germ cell tumors: incidence and possible biological implications. Genes Chromosom. Cancer 12, 110-116 (1995).
    • (1995) Genes Chromosom. Cancer , vol.12 , pp. 110-116
    • Olie, R.-A.1
  • 103
    • 58449137403 scopus 로고    scopus 로고
    • Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents
    • Gilbert, D. C. et-al. Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents. J. Pathol. 217, 94-102 (2009).
    • (2009) J. Pathol. , vol.217 , pp. 94-102
    • Gilbert, D.-C.1
  • 105
    • 0042529190 scopus 로고    scopus 로고
    • Expression of HER-2/neu in testicular tumors
    • Mandoky, L., Geczi, L., Bodrogi, I., Toth, J. & Bak, M. Expression of HER-2/neu in testicular tumors. Anticancer Res. 23, 3447-3451 (2003). (Pubitemid 36975447)
    • (2003) Anticancer Research , vol.23 , Issue.4 , pp. 3447-3451
    • Mandoky, L.1    Geczi, L.2    Bodrogi, I.3    Toth, J.4    Bak, M.5
  • 106
    • 78650959224 scopus 로고    scopus 로고
    • Minimum regions of genomic imbalance in stage i testicular embryonal carcinoma and association of 22q loss with relapse
    • Gilbert, D. C. et-al. Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse. Genes Chromosom. Cancer 50, 186-195 (2011).
    • (2011) Genes Chromosom. Cancer , vol.50 , pp. 186-195
    • Gilbert, D.-C.1
  • 107
    • 1242340431 scopus 로고    scopus 로고
    • Oncogenic Ras and its role in tumor cell invasion and metastasis
    • DOI 10.1016/j.semcancer.2003.09.015
    • Campbell, P. M. & Der, C. J. Oncogenic Ras and its role in tumor cell invasion and metastasis. Semin. Cancer Biol. 14, 105-114 (2004). (Pubitemid 38234752)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.2 , pp. 105-114
    • Campbell, P.M.1    Der, C.J.2
  • 108
    • 1642553461 scopus 로고    scopus 로고
    • The dark side of Ras: Regulation of apoptosis
    • DOI 10.1038/sj.onc.1207111, Apoptosis - Part 2
    • Cox, A. D. & Der, C. J. The dark side of Ras: regulation of apoptosis. Oncogene 22, 8999-9006 (2003). (Pubitemid 38121700)
    • (2003) Oncogene , vol.22 , Issue.56 REV. ISSUE 8 , pp. 8999-9006
    • Cox, A.D.1    Der, C.J.2
  • 109
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • DOI 10.1038/nrc969
    • Downward, J. Targeting RAS signalling pathways in cancer therapy. Nature Rev. Cancer 3, 11-22 (2003). (Pubitemid 37328883)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.1 , pp. 11-22
    • Downward, J.1
  • 110
    • 0030884103 scopus 로고    scopus 로고
    • PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
    • Marte, B. M. & Downward, J. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem. Sci. 22, 355-358 (1997).
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 355-358
    • Marte, B.M.1    Downward, J.2
  • 111
    • 0346849702 scopus 로고    scopus 로고
    • Akt/PTEN signaling mediates estrogen-dependent proliferation of primordial germ cells in-vitro
    • Moe-Behrens, G. H. et-al. Akt/PTEN signaling mediates estrogen-dependent proliferation of primordial germ cells in-vitro. Mol. Endocrinol. 17, 2630-2638 (2003).
    • (2003) Mol. Endocrinol. , vol.17 , pp. 2630-2638
    • Moe-Behrens, G.-H.1
  • 113
    • 14444269482 scopus 로고    scopus 로고
    • MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines
    • Teng, D. H. et-al. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res. 57, 5221-5225 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 5221-5225
    • Teng, D.-H.1
  • 116
    • 65549094095 scopus 로고    scopus 로고
    • Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors
    • Honecker, F. et-al. Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors. J. Clin. Oncol. 27, 2129-2136 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2129-2136
    • Honecker, F.1
  • 117
    • 18544379954 scopus 로고    scopus 로고
    • Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells
    • DOI 10.1182/blood-2004-11-4349
    • Kortesidis, A. et-al. Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood 105, 3793-3801 (2005). (Pubitemid 40656121)
    • (2005) Blood , vol.105 , Issue.10 , pp. 3793-3801
    • Kortesidis, A.1    Zannettino, A.2    Isenmann, S.3    Shi, S.4    Lapidot, T.5    Gronthos, S.6
  • 118
    • 33846474121 scopus 로고    scopus 로고
    • G-protein-coupled receptors and cancer
    • DOI 10.1038/nrc2069, PII NRC2069
    • Dorsam, R. T. & Gutkind, J. S. G-protein-coupled receptors and cancer. Nature Rev. Cancer 7, 79-94 (2007). (Pubitemid 46164746)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.2 , pp. 79-94
    • Dorsam, R.T.1    Gutkind, J.S.2
  • 122
    • 28544440733 scopus 로고    scopus 로고
    • Differential expression of CXCR4 is associated with the metastatic potential of human non-small cell lung cancer cells
    • DOI 10.1158/1078-0432.CCR-05-0537
    • Su, L. et-al. Differential expression of CXCR4 is associated with the metastatic potential of human non-small cell lung cancer cells. Clin. Cancer Res. 11, 8273-8280 (2005). (Pubitemid 41746937)
    • (2005) Clinical Cancer Research , vol.11 , Issue.23 , pp. 8273-8280
    • Su, L.1    Zhang, J.2    Xu, H.3    Wang, Y.4    Chu, Y.5    Liu, R.6    Xiong, S.7
  • 125
    • 34547634399 scopus 로고    scopus 로고
    • CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models
    • DOI 10.1158/0008-5472.CAN-06-2263
    • Yoon, Y. et-al. CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models. Cancer Res. 67, 7518-7524 (2007). (Pubitemid 47206582)
    • (2007) Cancer Research , vol.67 , Issue.15 , pp. 7518-7524
    • Yoon, Y.1    Liang, Z.2    Zhang, X.3    Choe, M.4    Zhu, A.5    Cho, H.T.6    Shin, D.M.7    Goodman, M.M.8    Chen, Z.9    Shim, H.10
  • 126
    • 29344451650 scopus 로고    scopus 로고
    • CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: The role of bone microenvironment-associated CXCL12
    • DOI 10.1002/pros.20318
    • Chinni, S. R. et-al. CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment- associated CXCL12. Prostate 66, 32-48 (2006). (Pubitemid 43005947)
    • (2006) Prostate , vol.66 , Issue.1 , pp. 32-48
    • Chinni, S.R.1    Sivalogan, S.2    Dong, Z.3    Trindade Filho, J.C.4    Deng, X.5    Bonfil, R.D.6    Cher, M.L.7
  • 127
    • 33646598696 scopus 로고    scopus 로고
    • CXCR4 expression mediates glioma cell invasiveness
    • Ehtesham, M., Winston, J. A., Kabos, P. & Thompson, R. C. CXCR4 expression mediates glioma cell invasiveness. Oncogene 25, 2801-2806 (2006).
    • (2006) Oncogene , vol.25 , pp. 2801-2806
    • Ehtesham, M.1    Winston, J.A.2    Kabos, P.3    Thompson, R.C.4
  • 128
    • 0942301172 scopus 로고    scopus 로고
    • Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells
    • DOI 10.1038/sj.onc.1206910
    • Fernandis, A. Z., Prasad, A., Band, H., Klosel, R. & Ganju, R. K. Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells. Oncogene 23, 157-167 (2004). (Pubitemid 38142250)
    • (2004) Oncogene , vol.23 , Issue.1 , pp. 157-167
    • Fernandis, A.Z.1    Prasad, A.2    Band, H.3    Klosel, R.4    Ganju, R.K.5
  • 129
    • 24344436325 scopus 로고    scopus 로고
    • Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis
    • DOI 10.1016/j.cellsig.2005.03.022, PII S0898656805000677
    • Wang, J. et-al. Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis. Cell. Signal. 17, 1578-1592 (2005). (Pubitemid 41253997)
    • (2005) Cellular Signalling , vol.17 , Issue.12 , pp. 1578-1592
    • Wang, J.1    Wang, J.2    Sun, Y.3    Song, W.4    Nor, J.E.5    Wang, C.Y.6    Taichman, R.S.7
  • 131
    • 0142149043 scopus 로고    scopus 로고
    • Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus
    • Plotkin, J., Prockop, S. E., Lepique, A. & Petrie, H. T. Critical role for CXCR4 signaling in progenitor localization and T Cell differentiation in the postnatal thymus. J. Immunol. 171, 4521-4527 (2003). (Pubitemid 37310567)
    • (2003) Journal of Immunology , vol.171 , Issue.9 , pp. 4521-4527
    • Plotkin, J.1    Prockop, S.E.2    Lepique, A.3    Petrie, H.T.4
  • 132
    • 76149086153 scopus 로고    scopus 로고
    • Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4
    • Janas, M. L. et-al. Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4. J.-Exp. Med. 207, 247-261 (2010).
    • (2010) J.-Exp. Med. , vol.207 , pp. 247-261
    • Janas, M.-L.1
  • 133
    • 75649136915 scopus 로고    scopus 로고
    • CXCR4 acts as a costimulator during thymic β-selection
    • Trampont, P. C. et-al. CXCR4 acts as a costimulator during thymic β-selection. Nature Immunol. 11, 162-170 (2010).
    • (2010) Nature Immunol. , vol.11 , pp. 162-170
    • Trampont, P.-C.1
  • 134
    • 39849096261 scopus 로고    scopus 로고
    • Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells
    • DOI 10.1038/sj.onc.1210751, PII 1210751
    • Wendt, M. K., Cooper, A. N. & Dwinell, M. B. Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells. Oncogene 27, 1461-1471 (2008). (Pubitemid 351317456)
    • (2008) Oncogene , vol.27 , Issue.10 , pp. 1461-1471
    • Wendt, M.K.1    Cooper, A.N.2    Dwinell, M.B.3
  • 135
    • 33747371948 scopus 로고    scopus 로고
    • Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis
    • Wendt, M. K. et-al. Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. Oncogene 25, 4986-4997 (2006).
    • (2006) Oncogene , vol.25 , pp. 4986-4997
    • Wendt, M.K.1
  • 136
    • 34848905963 scopus 로고    scopus 로고
    • Polymorphism and circulating levels of the chemokine CXCL12 in colorectal cancer patients
    • Dimberg, J., Hugander, A., Lofgren, S. & Wagsater, D. Polymorphism and circulating levels of the chemokine CXCL12 in colorectal cancer patients. Int. J. Mol. Med. 19, 11-15 (2007).
    • (2007) Int. J. Mol. Med. , vol.19 , pp. 11-15
    • Dimberg, J.1    Hugander, A.2    Lofgren, S.3    Wagsater, D.4
  • 137
    • 38949136379 scopus 로고    scopus 로고
    • Plasma stromal cell - derived factor-1: Host derived marker predictive of distant metastasis in breast cancer
    • DOI 10.1158/1078-0432.CCR-07-1189
    • Hassan, S., Baccarelli, A., Salvucci, O. & Basik, M. Plasma stromal cell-derived factor-1: host derived marker predictive of distant metastasis in breast cancer. Clin. Cancer Res. 14, 446-454 (2008). (Pubitemid 351226112)
    • (2008) Clinical Cancer Research , vol.14 , Issue.2 , pp. 446-454
    • Hassan, S.1    Baccarelli, A.2    Salvucci, O.3    Basik, M.4
  • 138
    • 77958506768 scopus 로고    scopus 로고
    • CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through bim-mediated intrinsic apoptosis
    • Drury, L. J., Wendt, M. K. & Dwinell, M. B. CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through bim-mediated intrinsic apoptosis. PLoS ONE 5, e12895.
    • PLoS ONE , vol.5
    • Drury, L.J.1    Wendt, M.K.2    Dwinell, M.B.3
  • 139
    • 34248201052 scopus 로고    scopus 로고
    • The evolution of sex chromosomes and sex determination in vertebrates and the key role of DMRT1
    • DOI 10.1159/000096234
    • Ferguson-Smith, M. The evolution of sex chromosomes and sex determination in vertebrates and the key role of DMRT1. Sex. Dev. 1, 2-11 (2007). (Pubitemid 46709082)
    • (2007) Sexual Development , vol.1 , Issue.1 , pp. 2-11
    • Ferguson-Smith, M.1
  • 143
    • 70350379382 scopus 로고    scopus 로고
    • Characterization of deletions at 9p affecting the candidate regions for sex reversal and deletion 9p syndrome by MLPA
    • Barbaro, M. et-al. Characterization of deletions at 9p affecting the candidate regions for sex reversal and deletion 9p syndrome by MLPA. Eur. J. Hum. Genet. 17, 1439-1447 (2009).
    • (2009) Eur. J. Hum. Genet. , vol.17 , pp. 1439-1447
    • Barbaro, M.1
  • 145
    • 76049089134 scopus 로고    scopus 로고
    • The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency
    • Krentz, A. D. et-al. The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency. Proc. Natl Acad. Sci. USA 106, 22323-22328 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 22323-22328
    • Krentz, A.-D.1
  • 146
    • 0042386051 scopus 로고    scopus 로고
    • Telomere dysfunction and the initiation of genome instability
    • DOI 10.1038/nrc1142
    • Feldser, D. M., Hackett, J. A. & Greider, C. W. Telomere dysfunction and the initiation of genome instability. Nature Rev. Cancer 3, 623-627 (2003). (Pubitemid 37328834)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.8 , pp. 623-627
    • Feldser, D.M.1    Hackett, J.A.2    Greider, C.W.3
  • 147
    • 0035839132 scopus 로고    scopus 로고
    • Telomere dysfunction increases mutation rate and genomic instability
    • DOI 10.1016/S0092-8674(01)00457-3
    • Hackett, J. A., Feldser, D. M. & Greider, C. W. Telomere dysfunction increases mutation rate and genomic instability. Cell 106, 275-286 (2001). (Pubitemid 32772612)
    • (2001) Cell , vol.106 , Issue.3 , pp. 275-286
    • Hackett, J.A.1    Feldser, D.M.2    Greider, C.W.3
  • 149
    • 34249001353 scopus 로고    scopus 로고
    • Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis
    • DOI 10.1016/j.exphem.2007.03.009, PII S0301472X07001920
    • Widmann, T. A., Herrmann, M., Taha, N., Konig, J. & Pfreundschuh, M. Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis. Exp. Hematol. 35, 939-946 (2007). (Pubitemid 46802988)
    • (2007) Experimental Hematology , vol.35 , Issue.6 , pp. 939-946
    • Widmann, T.A.1    Herrmann, M.2    Taha, N.3    Konig, J.4    Pfreundschuh, M.5
  • 152
    • 40049087659 scopus 로고    scopus 로고
    • Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer
    • DOI 10.1016/j.cancergencyto.2007.12.004, PII S0165460807008096
    • Kang, J. U., Koo, S. H., Kwon, K. C., Park, J. W. & Kim, J. M. Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer. Cancer Genet. Cytogenet. 182, 1-11 (2008). (Pubitemid 351323956)
    • (2008) Cancer Genetics and Cytogenetics , vol.182 , Issue.1 , pp. 1-11
    • Kang, J.U.1    Koo, S.H.2    Kwon, K.C.3    Park, J.W.4    Kim, J.M.5
  • 153
    • 0037057508 scopus 로고    scopus 로고
    • Genetic alterations in cervical carcinomas: Frequent low-level amplifications of oncogenes are associated with human papillomavirus infection
    • Zhang, A. et-al. Genetic alterations in cervical carcinomas: frequent low-level amplifications of oncogenes are associated with human papillomavirus infection. Int. J. Cancer 101, 427-433 (2002).
    • (2002) Int. J. Cancer , vol.101 , pp. 427-433
    • Zhang, A.1
  • 154
    • 3042841178 scopus 로고    scopus 로고
    • The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase
    • Schrader, M. et-al. The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase. BMC Cancer 2, 32 (2002).
    • (2002) BMC Cancer , vol.2 , pp. 32
    • Schrader, M.1
  • 155
    • 0036731389 scopus 로고    scopus 로고
    • Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR
    • Schrader, M. et-al. Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR. Oncol. Rep. 9, 1097-1105 (2002).
    • (2002) Oncol. Rep. , vol.9 , pp. 1097-1105
    • Schrader, M.1
  • 156
    • 64149129167 scopus 로고    scopus 로고
    • MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity
    • Liu, L. et-al. MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity. J. Biol. Chem. 284, 5165-5174 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 5165-5174
    • Liu, L.1
  • 157
    • 79251600304 scopus 로고    scopus 로고
    • Polymorphic variation in the androgen receptor gene: Association with risk of testicular germ cell cancer and metastatic disease
    • Vastermark, K. et-al. Polymorphic variation in the androgen receptor gene: association with risk of testicular germ cell cancer and metastatic disease. Eur. J. Cancer 47, 413-419 (2010).
    • (2010) Eur. J. Cancer , vol.47 , pp. 413-419
    • Vastermark, K.1
  • 158
    • 33750063440 scopus 로고    scopus 로고
    • Male infertility and androgen receptor gene mutations: Clinical features and identification of seven novel mutations
    • DOI 10.1111/j.1365-2265.2006.02635.x
    • Ferlin, A. et-al. Male infertility and androgen receptor gene mutations: clinical features and identification of seven novel mutations. Clin. Endocrinol. 65, 606-610 (2006). (Pubitemid 44583820)
    • (2006) Clinical Endocrinology , vol.65 , Issue.5 , pp. 606-610
    • Ferlin, A.1    Vinanzi, C.2    Garolla, A.3    Selice, R.4    Zuccarello, D.5    Cazzadore, C.6    Foresta, C.7
  • 159
    • 0034803720 scopus 로고    scopus 로고
    • Screening for mutations of the androgen receptor gene in patients with isolated cryptorchidism
    • DOI 10.1016/S0015-0282(01)02016-7, PII S0015028201020167
    • Suzuki, Y. et-al. Screening for mutations of the androgen receptor gene in patients with isolated cryptorchidism. Fertil. Steril. 76, 834-836 (2001). (Pubitemid 32928416)
    • (2001) Fertility and Sterility , vol.76 , Issue.4 , pp. 834-836
    • Suzuki, Y.1    Sasagawa, I.2    Ashida, J.3    Nakada, T.4    Muroya, K.5    Ogata, T.6
  • 160
    • 0034889049 scopus 로고    scopus 로고
    • Mutation screening and CAG repeat length analysis of the androgen receptor gene in Klinefelter's syndrome patients with and without spermatogenesis
    • Suzuki, Y. et-al. Mutation screening and CAG repeat length analysis of the androgen receptor gene in Klinefelter's syndrome patients with and without spermatogenesis. Hum. Reprod. 16, 1653-1656 (2001). (Pubitemid 32761745)
    • (2001) Human Reproduction , vol.16 , Issue.8 , pp. 1653-1656
    • Suzuki, Y.1    Sasagawa, I.2    Tateno, T.3    Ashida, J.4    Nakada, T.5    Muroya, K.6    Ogata, T.7
  • 161
    • 0032323778 scopus 로고    scopus 로고
    • Androgen receptor gene alterations are not associated with isolated cryptorchidism
    • DOI 10.1016/S0022-5347(01)62823-4
    • Wiener, J. S., Marcelli, M., Gonzales, E. T., Jr, Roth,-D. R. & Lamb, D. J. Androgen receptor gene alterations are not associated with isolated cryptorchidism. J. Urol. 160, 863-865 (1998). (Pubitemid 29479545)
    • (1998) Journal of Urology , vol.160 , Issue.3 , pp. 863-865
    • Wiener, J.S.1    Marcelli, M.2    Gonzales Jr., E.T.3    Roth, D.R.4    Lamb, D.J.5
  • 162
    • 6344229471 scopus 로고    scopus 로고
    • Linkage between cryptorchidism, hypospadias, and GGN repeat length in the androgen receptor gene
    • Aschim, E. L. et-al. Linkage between cryptorchidism, hypospadias, and GGN repeat length in the androgen receptor gene. J. Clin. Endocrinol. Metab. 89, 5105-5109 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 5105-5109
    • Aschim, E.-L.1
  • 164
    • 33846024722 scopus 로고    scopus 로고
    • Association of long polyglycine tracts (GGN Repeats) in exon 1 of the androgen receptor gene with cryptorchidism and penile hypospadias in Iranian patients
    • DOI 10.2164/jandrol.106.000927
    • Radpour, R., Rezaee, M., Tavasoly, A., Solati, S. & Saleki, A. Association of long polyglycine tracts (GGN repeats) in exon 1 of the androgen receptor gene with cryptorchidism and penile hypospadias in Iranian patients. J. Androl. 28, 164-169 (2007). (Pubitemid 46048090)
    • (2007) Journal of Andrology , vol.28 , Issue.1 , pp. 164-169
    • Radpour, R.1    Rezaee, M.2    Tavasoly, A.3    Solati, S.4    Saleki, A.5
  • 165
    • 33745960757 scopus 로고    scopus 로고
    • The CAG repeat within the androgen receptor gene and its relationship to cryptorchidism
    • Silva-Ramos, M. et-al. The CAG repeat within the androgen receptor gene and its relationship to cryptorchidism. Int. Braz. J. Urol. 32, 330-335 (2006).
    • (2006) Int. Braz. J. Urol. , vol.32 , pp. 330-335
    • Silva-Ramos, M.1
  • 166
    • 0028033594 scopus 로고
    • The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function
    • Chamberlain, N. L., Driver, E. D. & Miesfeld, R. L. The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function. Nucleic Acids Res. 22, 3181-3186 (1994). (Pubitemid 24260654)
    • (1994) Nucleic Acids Research , vol.22 , Issue.15 , pp. 3181-3186
    • Chamberlain, N.L.1    Driver, E.D.2    Miesfeld, R.L.3
  • 167
    • 0029856398 scopus 로고    scopus 로고
    • Reduced androgen receptor gene expression with first exon CAG repeat expansion
    • DOI 10.1210/me.10.12.1527
    • Choong, C. S., Kemppainen, J. A., Zhou, Z. X. & Wilson, E. M. Reduced androgen receptor gene expression with first exon CAG repeat expansion. Mol. Endocrinol. 10, 1527-1535 (1996). (Pubitemid 26408742)
    • (1996) Molecular Endocrinology , vol.10 , Issue.12 , pp. 1527-1535
    • Choong, C.S.1    Kemppainen, J.A.2    Zhou, Z.-X.3    Wilson, E.M.4
  • 168
    • 0029129227 scopus 로고
    • Spinal and bulbar muscular atrophy: A trinucleotide-repeat expansion neurodegenerative disease
    • Brooks, B. P. & Fischbeck, K. H. Spinal and bulbar muscular atrophy: a trinucleotide-repeat expansion neurodegenerative disease. Trends Neurosci. 18, 459-461 (1995).
    • (1995) Trends Neurosci. , vol.18 , pp. 459-461
    • Brooks, B.P.1    Fischbeck, K.H.2
  • 169
    • 0028922314 scopus 로고
    • Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: Possible pathogenetic relevance for the (CAG)n-expanded neuronopathies
    • Kazemi-Esfarjani, P., Trifiro, M. A. & Pinsky, L. Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)n-expanded neuronopathies. Hum. Mol. Genet. 4, 523-527 (1995).
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 523-527
    • Kazemi-Esfarjani, P.1    Trifiro, M.A.2    Pinsky, L.3
  • 170
    • 0019468735 scopus 로고
    • Genetics of undescended testis
    • Czeizel, A., Erodi, E. & Toth, J. Genetics of undescended testis. J. Urol. 126, 528-529 (1981). (Pubitemid 11020110)
    • (1981) Journal of Urology , vol.126 , Issue.4 , pp. 528-529
    • Czeizel, A.1    Erodi, E.2    Toth, J.3
  • 171
    • 32544458807 scopus 로고    scopus 로고
    • Population-based investigation of familial undescended testis and its association with other urogenital anomalies
    • DOI 10.1016/j.jpurol.2005.04.005, PII S1477513105000951
    • Elert, A., Jahn, K., Heidenreich, A. & Hofmann, R. Population-based investigation of familial undescended testis and its association with other urogenital anomalies. J. Pediatr. Urol. 1, 403-407 (2005). (Pubitemid 43230264)
    • (2005) Journal of Pediatric Urology , vol.1 , Issue.6 , pp. 403-407
    • Elert, A.1    Jahn, K.2    Heidenreich, A.3    Hofmann, R.4
  • 173
    • 0037343516 scopus 로고    scopus 로고
    • INK4d, MAGE-A4 and other selected antigens provides new evidence for the premeiotic origin of spermatocytic seminoma
    • DOI 10.1046/j.1365-2559.2003.01587.x
    • Rajpert-De Meyts, E. et-al. The immunohistochemical expression pattern of Chk2, p53, p19INK4d, MAGE-A4 and other selected antigens provides new evidence for the premeiotic origin of spermatocytic seminoma. Histopathology 42, 217-226 (2003). (Pubitemid 36356853)
    • (2003) Histopathology , vol.42 , Issue.3 , pp. 217-226
    • Rajpert-De Meyts, E.1    Jacobsen, G.K.2    Bartkova, J.3    Aubry, F.4    Samson, M.5    Bartek, J.6    Skakkebaek, N.E.7
  • 174
    • 70350646899 scopus 로고    scopus 로고
    • Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors
    • Goriely, A. et-al. Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors. Nature Genet. 41, 1247-1252 (2009).
    • (2009) Nature Genet. , vol.41 , pp. 1247-1252
    • Goriely, A.1
  • 176
    • 25844442348 scopus 로고    scopus 로고
    • IGF2/H19 imprinting analysis of human germ cell tumors (GCTs) using the methylation-sensitive single-nucleotide primer extension method reflects the origin of GCTs in different stages of primordial germ cell development
    • DOI 10.1002/gcc.20237
    • Sievers, S. et-al. IGF2/H19 imprinting analysis of human germ cell tumors (GCTs) using the methylation-sensitive single-nucleotide primer extension method reflects the origin of GCTs in different stages of primordial germ cell development. Genes Chromosom. Cancer 44, 256-264 (2005). (Pubitemid 41397094)
    • (2005) Genes Chromosomes and Cancer , vol.44 , Issue.3 , pp. 256-264
    • Sievers, S.1    Alemazkour, K.2    Zahn, S.3    Perlman, E.J.4    Gillis, A.J.M.5    Looijenga, L.H.J.6    Gobel, U.7    Schneider, D.T.8
  • 177
    • 7244238096 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis of human spermatocytic seminomas
    • DOI 10.1002/path.1634
    • Verdorfer, I., Rogatsch, H., Tzankov, A., Steiner, H. & Mikuz, G. Molecular cytogenetic analysis of human spermatocytic seminomas. J. Pathol. 204, 277-281 (2004). (Pubitemid 39430086)
    • (2004) Journal of Pathology , vol.204 , Issue.3 , pp. 277-281
    • Verdorfer, I.1    Rogatsch, H.2    Tzankov, A.3    Steiner, H.4    Mikuz, G.5
  • 178
    • 31544473100 scopus 로고    scopus 로고
    • Genomic and expression profiling of human spermatocytic seminomas: Primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene
    • Looijenga, L. H. et-al. Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Res. 66, 290-302 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 290-302
    • Looijenga, L.-H.1
  • 179
    • 50249160667 scopus 로고    scopus 로고
    • Stem cell factor as a novel diagnostic marker for early malignant germ cells
    • Stoop, H. et-al. Stem cell factor as a novel diagnostic marker for early malignant germ cells. J. Pathol. 216, 43-54 (2008).
    • (2008) J. Pathol. , vol.216 , pp. 43-54
    • Stoop, H.1
  • 181
    • 0029866244 scopus 로고    scopus 로고
    • Short-course adjuvant chemotherapy in high-risk stage i nonseminomatous germ cell tumors of the testis: A Medical Research Council report
    • Cullen, M. H. et-al. Short-course adjuvant chemotherapy in high-risk stage I nonseminomatous germ cell tumors of the testis: a Medical Research Council report. J. Clin. Oncol. 14, 1106-1113 (1996).
    • (1996) J. Clin. Oncol. , vol.14 , pp. 1106-1113
    • Cullen, M.-H.1
  • 182
    • 33745075685 scopus 로고    scopus 로고
    • Treating stage i nonseminomatous germ cell tumours with a single cycle of chemotherapy
    • Gilbert, D. C. et-al. Treating stage I nonseminomatous germ cell tumours with a single cycle of chemotherapy. BJU Int. 98, 67-69 (2006).
    • (2006) BJU Int. , vol.98 , pp. 67-69
    • Gilbert, D.-C.1
  • 183
    • 36749062011 scopus 로고    scopus 로고
    • Long-term followup results of 1 cycle of adjuvant bleomycin, etoposide and cisplatin chemotherapy for high risk clinical stage i nonseminomatous germ cell tumors of the testis
    • Westermann, D. H. et-al. Long-term followup results of 1 cycle of adjuvant bleomycin, etoposide and cisplatin chemotherapy for high risk clinical stage I nonseminomatous germ cell tumors of the testis. J. Urol. 179, 163-166 (2008).
    • (2008) J. Urol. , vol.179 , pp. 163-166
    • Westermann, D.-H.1
  • 184
    • 0025152039 scopus 로고
    • Treatment of testicular cancer: A new and improved model
    • Einhorn, L. H. Treatment of testicular cancer: a new and improved model. J. Clin. Oncol. 8, 1777-1781 (1990).
    • (1990) J. Clin. Oncol. , vol.8 , pp. 1777-1781
    • Einhorn, L.-H.1
  • 185
    • 0033545701 scopus 로고    scopus 로고
    • Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours
    • DOI 10.1016/S0960-9822(99)80118-3
    • Koberle, B., Masters, J. R., Hartley, J. A. & Wood, R. D. Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours. Curr. Biol. 9, 273-276 (1999). (Pubitemid 29139312)
    • (1999) Current Biology , vol.9 , Issue.5 , pp. 273-276
    • Koberle, B.1    Masters, J.R.W.2    Hartley, J.A.3    Wood, R.D.4
  • 186
    • 0043240184 scopus 로고    scopus 로고
    • Curing metastatic cancer: Lessons from testicular germ-cell tumours
    • Masters, J. R. & Koberle, B. Curing metastatic cancer: lessons from testicular germ Cell tumours. Nature Rev. Cancer 3, 517-525 (2003). (Pubitemid 37328839)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.7 , pp. 517-525
    • Masters, J.R.W.1    Koberle, B.2
  • 187
    • 77956621875 scopus 로고    scopus 로고
    • Phase-II trial of sunitinib in patients with relapsed or refractory germ cell tumors
    • Feldman, D. R. et-al. Phase-II trial of sunitinib in patients with relapsed or refractory germ cell tumors. Invest. New Drugs 28, 523-528 (2010).
    • (2010) Invest. New Drugs , vol.28 , pp. 523-528
    • Feldman, D.-R.1
  • 188
    • 77953177417 scopus 로고    scopus 로고
    • The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers
    • Noel, E. E. et-al. The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers. Am. J. Pathol. 176, 2607-2615 (2010).
    • (2010) Am. J. Pathol. , vol.176 , pp. 2607-2615
    • Noel, E.-E.1
  • 189
    • 70449730662 scopus 로고    scopus 로고
    • Identification and validation of a gene expression signature that predicts outcome in adult men with germ cell tumors
    • Korkola, J. E. et-al. Identification and validation of a gene expression signature that predicts outcome in adult men with germ cell tumors. J. Clin. Oncol. 27, 5240-5247 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5240-5247
    • Korkola, J.-E.1
  • 190
    • 33646085352 scopus 로고    scopus 로고
    • Loss of Oct-3/4 expression in embryonal carcinoma cells is associated with induction of cisplatin resistance
    • Mueller, T. et-al. Loss of Oct-3/4 expression in embryonal carcinoma cells is associated with induction of cisplatin resistance. Tumour Biol. 27, 71-83 (2006).
    • (2006) Tumour Biol. , vol.27 , pp. 71-83
    • Mueller, T.1
  • 191
    • 73649099925 scopus 로고    scopus 로고
    • High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors
    • Beyrouthy, M. J. et-al. High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors. Cancer Res. 69, 9360-9366 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 9360-9366
    • Beyrouthy, M.-J.1
  • 192
    • 77957832584 scopus 로고    scopus 로고
    • Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer
    • Koster, R. et-al. Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer. J. Clin. Invest. 120, 3594-3605 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 3594-3605
    • Koster, R.1
  • 193
    • 3042850560 scopus 로고    scopus 로고
    • Waf1/Cip1 protein level sensitizes testicular germ cell tumor cells to Fas-mediated apoptosis
    • DOI 10.1038/sj.onc.1207617
    • Spierings, D. C. et-al. Low p21Waf1/Cip1 protein level sensitizes testicular germ cell tumor cells to Fas-mediated apoptosis. Oncogene 23, 4862-4872 (2004). (Pubitemid 38937046)
    • (2004) Oncogene , vol.23 , Issue.28 , pp. 4862-4872
    • Spierings, D.C.J.1    De Vries, E.G.E.2    Stel, A.J.3    Te Rietstap, N.4    Vellenga, E.5    De Long, S.6
  • 194
    • 34249315487 scopus 로고    scopus 로고
    • Morphogens morphostats, microarchitecture and malignancy
    • Potter, J. D. Morphogens, morphostats, microarchitecture and malignancy. Nature Rev. Cancer 7, 464-474 (2007).
    • (2007) Nature Rev. Cancer , vol.7 , pp. 464-474
    • Potter, J.D.1
  • 195
    • 0014758977 scopus 로고
    • The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos
    • Stevens, L. C. The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos. Dev. Biol. 21, 364-382 (1970).
    • (1970) Dev. Biol. , vol.21 , pp. 364-382
    • Stevens, L.-C.1
  • 196
    • 84965084971 scopus 로고
    • Teratocarcinogenic and tissue-forming potentials of the cell types comprising neoplastic embryoid bodies
    • Pierce, G. B. Jr, Dixon, F. J. Jr & Verney, E. L. Teratocarcinogenic and tissue-forming potentials of the cell types comprising neoplastic embryoid bodies. Lab. Invest. 9, 583-602 (1960).
    • (1960) Lab. Invest. , vol.9 , pp. 583-602
    • Pierce Jr., G.B.1    Dixon Jr., F.J.2    Verney, E.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.